Chemical mutagenesis of dengue virus type 4 yields mutant viruses which are temperature sensitive in vero cells or human liver cells and attenuated in mice

Journal of Virology

Volumn 75, Issue 20, 2001, Pages 9731-9740

  Blaney J E , Jr ^a   Johnson, D H ^a   Firestone, C Y ^a   Hanson, C T ^a   Murphy, B R ^a   Whitehead, S S ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3' UNTRANSLATED REGION; ANIMAL CELL; ARTICLE; CHEMICAL MUTAGENESIS; DENGUE VIRUS; GENE DELETION; GENE STRUCTURE; HUMAN; HUMAN CELL; LIVER CELL; MOUSE; NONHUMAN; NUCLEIC ACID BASE SUBSTITUTION; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; TEMPERATURE SENSITIVE MUTANT; VERO CELL; VIROGENESIS; VIRUS GENOME; VIRUS MUTANT; VIRUS PATHOGENESIS; VIRUS RECOMBINANT; VIRUS REPLICATION;

3' UNTRANSLATED REGIONS; 5' UNTRANSLATED REGIONS; ANIMALS; ANIMALS, SUCKLING; BRAIN; CELL LINE; CERCOPITHECUS AETHIOPS; CLONING, MOLECULAR; DENGUE; DENGUE VIRUS; FLUOROURACIL; GENES, VIRAL; GENOME, VIRAL; HUMANS; MICE; MOLECULAR SEQUENCE DATA; MUTAGENS; RECOMBINATION, GENETIC; RNA HELICASES; SERINE ENDOPEPTIDASES; TEMPERATURE; VACCINES, ATTENUATED; VERO CELLS; VIRAL NONSTRUCTURAL PROTEINS; VIRAL VACCINES; VIRUS REPLICATION;

EID: 0034801795     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.75.20.9731-9740.2001     Document Type: Article

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