Silica-induced TNF-α and TGF-β1 expression in RAW264.7 cells are dependent on Src-ERK/AP-1 pathways

Toxicology Mechanisms and Methods

Volumn 19, Issue 1, 2009, Pages 51-58

  Li, Xiang ^a   Hu, Yongbin ^a   Jin, Zhongyuan ^a   Jiang, Haiying ^a   Wen, Jifang ^a  

^a Central South University   (China)

Author keywords

Activator protein 1; Mitogen activated protein kinase; Silica; Src tyrosine kinases; Transforming growth factor 1; Tumor necrosis factor

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; 4 AMINO 7 TERT BUTYL 5 (4 METHYLPHENYL)PYRAZOLO[3,4 D]PYRIMIDINE; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1; INTERLEUKIN 6; INTERLEUKIN 8; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; MUTANT PROTEIN; NUCLEAR PROTEIN; PROTEIN TYROSINE KINASE; SILICON DIOXIDE; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR AP 1; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA; VASCULAR CELL ADHESION MOLECULE 1;

ARTICLE; BINDING AFFINITY; CELL CULTURE; CYTOKINE PRODUCTION; DNA BINDING; ENZYME LINKED IMMUNOSORBENT ASSAY; FIBROGENESIS; HUMAN; HUMAN CELL; MACROPHAGE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; UPREGULATION; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; CELL CULTURE TECHNIQUES; CELL LINE; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENVIRONMENTAL POLLUTANTS; ENZYME INHIBITORS; ENZYME-LINKED IMMUNOSORBENT ASSAY; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; MACROPHAGES, ALVEOLAR; MICE; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PEPTIDE FRAGMENTS; PHOSPHORYLATION; PLASMIDS; PROTEIN BINDING; PROTO-ONCOGENE PROTEINS C-JUN; SIGNAL TRANSDUCTION; SILICON DIOXIDE; SILICOSIS; SRC-FAMILY KINASES; TRANSCRIPTION FACTOR AP-1; TRANSFECTION; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR-ALPHA;

EID: 57149095928     PISSN: 15376516     EISSN: 15376524     Source Type: Journal    
DOI: 10.1080/15376510802354201     Document Type: Article

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