-
2
-
-
33846706434
-
The apical conjugate efflux pump ABCC2 (MRP2)
-
Nies A.T., and Keppler D. The apical conjugate efflux pump ABCC2 (MRP2). Pflugers Arch. 453 (2007) 643-659
-
(2007)
Pflugers Arch.
, vol.453
, pp. 643-659
-
-
Nies, A.T.1
Keppler, D.2
-
3
-
-
7544237299
-
The ABC transporters MDR1 and MRP2: multiple functions in disposition of xenobiotics and drug resistance
-
Hoffmann U., and Kroemer H.K. The ABC transporters MDR1 and MRP2: multiple functions in disposition of xenobiotics and drug resistance. Drug Metab. Rev. 36 (2004) 669-701
-
(2004)
Drug Metab. Rev.
, vol.36
, pp. 669-701
-
-
Hoffmann, U.1
Kroemer, H.K.2
-
4
-
-
0033745088
-
Hepatic secretion of conjugated drugs and endogenous substances
-
Keppler D., and Konig J. Hepatic secretion of conjugated drugs and endogenous substances. Semin. Liver Dis. 20 (2000) 265-272
-
(2000)
Semin. Liver Dis.
, vol.20
, pp. 265-272
-
-
Keppler, D.1
Konig, J.2
-
5
-
-
0037131880
-
Single nucleotide polymorphisms in multidrug resistance associated protein 2 (MRP2/ABCC2): its impact on drug disposition
-
Suzuki H., and Sugiyama Y. Single nucleotide polymorphisms in multidrug resistance associated protein 2 (MRP2/ABCC2): its impact on drug disposition. Adv. Drug Deliv. Rev. 54 (2002) 1311-1331
-
(2002)
Adv. Drug Deliv. Rev.
, vol.54
, pp. 1311-1331
-
-
Suzuki, H.1
Sugiyama, Y.2
-
6
-
-
0033008056
-
Enrichment of canalicular membrane with cholesterol and sphingomyelin prevents bile salt-induced hepatic damage
-
Amigo L., Mendoza H., Zanlungo S., Miquel J.F., Rigotti A., Gonzalez S., and Nervi F. Enrichment of canalicular membrane with cholesterol and sphingomyelin prevents bile salt-induced hepatic damage. J. Lipid Res. 40 (1999) 533-542
-
(1999)
J. Lipid Res.
, vol.40
, pp. 533-542
-
-
Amigo, L.1
Mendoza, H.2
Zanlungo, S.3
Miquel, J.F.4
Rigotti, A.5
Gonzalez, S.6
Nervi, F.7
-
7
-
-
33644503593
-
Isolation and characterization of lipid microdomains from apical and basolateral plasma membranes of rat hepatocytes
-
Mazzone A., Tietz P., Jefferson J., Pagano R., and LaRusso N.F. Isolation and characterization of lipid microdomains from apical and basolateral plasma membranes of rat hepatocytes. Hepatology 43 (2006) 287-296
-
(2006)
Hepatology
, vol.43
, pp. 287-296
-
-
Mazzone, A.1
Tietz, P.2
Jefferson, J.3
Pagano, R.4
LaRusso, N.F.5
-
8
-
-
33644859036
-
Hepatocanalicular transport defects: pathophysiologic mechanisms of rare diseases
-
Oude Elferink R.P., Paulusma C.C., and Groen A.K. Hepatocanalicular transport defects: pathophysiologic mechanisms of rare diseases. Gastroenterology 130 (2006) 908-925
-
(2006)
Gastroenterology
, vol.130
, pp. 908-925
-
-
Oude Elferink, R.P.1
Paulusma, C.C.2
Groen, A.K.3
-
9
-
-
0037323554
-
Raft-mediated trafficking of apical resident proteins occurs in both direct and transcytotic pathways in polarized hepatic cells: role of distinct lipid microdomains
-
Slimane T.A., Trugnan G., van IJzendoorn S., and Hoekstra D. Raft-mediated trafficking of apical resident proteins occurs in both direct and transcytotic pathways in polarized hepatic cells: role of distinct lipid microdomains. Mol. Biol. Cell 14 (2003) 611-624
-
(2003)
Mol. Biol. Cell
, vol.14
, pp. 611-624
-
-
Slimane, T.A.1
Trugnan, G.2
van IJzendoorn, S.3
Hoekstra, D.4
-
10
-
-
24744447260
-
Membrane microdomains in hepatocytes: potential target areas for proteins involved in canalicular bile secretion
-
Tietz P., Jefferson J., Pagano R., and Larusso N.F. Membrane microdomains in hepatocytes: potential target areas for proteins involved in canalicular bile secretion. J. Lipid Res. 46 (2005) 1426-1432
-
(2005)
J. Lipid Res.
, vol.46
, pp. 1426-1432
-
-
Tietz, P.1
Jefferson, J.2
Pagano, R.3
Larusso, N.F.4
-
11
-
-
27444434573
-
Drug resistance-associated changes in sphingolipids and ABC transporters occur in different regions of membrane domains
-
Hinrichs J.W., Klappe K., van Riezen M., and Kok J.W. Drug resistance-associated changes in sphingolipids and ABC transporters occur in different regions of membrane domains. J. Lipid Res. 46 (2005) 2367-2376
-
(2005)
J. Lipid Res.
, vol.46
, pp. 2367-2376
-
-
Hinrichs, J.W.1
Klappe, K.2
van Riezen, M.3
Kok, J.W.4
-
12
-
-
33744512299
-
Cholesterol and the interaction of proteins with membrane domains
-
Epand R.M. Cholesterol and the interaction of proteins with membrane domains. Prog. Lipid Res. 45 (2006) 279-294
-
(2006)
Prog. Lipid Res.
, vol.45
, pp. 279-294
-
-
Epand, R.M.1
-
13
-
-
0018161396
-
Procedure for determination of free and total cholesterol in micro- or nanogram amounts suitable for studies with cultured cells
-
Gamble W., Vaughan M., Kruth H.S., and Avigan J. Procedure for determination of free and total cholesterol in micro- or nanogram amounts suitable for studies with cultured cells. J. Lipid Res. 19 (1978) 1068-1070
-
(1978)
J. Lipid Res.
, vol.19
, pp. 1068-1070
-
-
Gamble, W.1
Vaughan, M.2
Kruth, H.S.3
Avigan, J.4
-
14
-
-
0037124051
-
Lipoplex-mediated transfection of mammalian cells occurs through the cholesterol-dependent clathrin-mediated pathway of endocytosis
-
Zuhorn I.S., Kalicharan R., and Hoekstra D. Lipoplex-mediated transfection of mammalian cells occurs through the cholesterol-dependent clathrin-mediated pathway of endocytosis. J. Biol. Chem. 277 (2002) 18021-18028
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 18021-18028
-
-
Zuhorn, I.S.1
Kalicharan, R.2
Hoekstra, D.3
-
15
-
-
34250333029
-
Cell polarity development and protein trafficking in hepatocytes lacking E-cadherin/beta-catenin-based adherens junctions
-
Théard D., Steiner M., Kalicharan D., Hoekstra D., and van IJzendoorn S. Cell polarity development and protein trafficking in hepatocytes lacking E-cadherin/beta-catenin-based adherens junctions. Mol. Biol. Cell 18 (2006) 2313-2321
-
(2006)
Mol. Biol. Cell
, vol.18
, pp. 2313-2321
-
-
Théard, D.1
Steiner, M.2
Kalicharan, D.3
Hoekstra, D.4
van IJzendoorn, S.5
-
16
-
-
0035038177
-
Tauroursodeoxycholic acid inserts the apical conjugate export pump, Mrp2, into canalicular membranes and stimulates organic anion secretion by protein kinase C-dependent mechanisms in cholestatic rat liver
-
Beuers U., Bilzer M., Chittattu A., Kullak-Ublick G.A., Keppler D., Paumgartner G., and Dombrowski F. Tauroursodeoxycholic acid inserts the apical conjugate export pump, Mrp2, into canalicular membranes and stimulates organic anion secretion by protein kinase C-dependent mechanisms in cholestatic rat liver. Hepatology 33 (2001) 1206-1216
-
(2001)
Hepatology
, vol.33
, pp. 1206-1216
-
-
Beuers, U.1
Bilzer, M.2
Chittattu, A.3
Kullak-Ublick, G.A.4
Keppler, D.5
Paumgartner, G.6
Dombrowski, F.7
-
17
-
-
0038381474
-
Taurolithocholic acid exerts cholestatic effects via phosphatidylinositol 3-kinase-dependent mechanisms in perfused rat livers and rat hepatocyte couplets
-
Beuers U., Denk G.U., Soroka C.J., Wimmer R., Rust C., Paumgartner G., and Boyer J.L. Taurolithocholic acid exerts cholestatic effects via phosphatidylinositol 3-kinase-dependent mechanisms in perfused rat livers and rat hepatocyte couplets. J. Biol. Chem. 278 (2003) 17810-17818
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 17810-17818
-
-
Beuers, U.1
Denk, G.U.2
Soroka, C.J.3
Wimmer, R.4
Rust, C.5
Paumgartner, G.6
Boyer, J.L.7
-
18
-
-
30944462200
-
Tauroursodeoxycholic acid inserts the bile salt export pump into canalicular membranes of cholestatic rat liver
-
Dombrowski F., Stieger B., and Beuers U. Tauroursodeoxycholic acid inserts the bile salt export pump into canalicular membranes of cholestatic rat liver. Lab. Invest. 86 (2006) 166-174
-
(2006)
Lab. Invest.
, vol.86
, pp. 166-174
-
-
Dombrowski, F.1
Stieger, B.2
Beuers, U.3
-
19
-
-
0037607657
-
The role of surfactants in the reversal of active transport mediated by multidrug resistance proteins
-
Bogman K., Erne-Brand F., Alsenz J., and Drewe J. The role of surfactants in the reversal of active transport mediated by multidrug resistance proteins. J. Pharm. Sci. 92 (2003) 1250-1261
-
(2003)
J. Pharm. Sci.
, vol.92
, pp. 1250-1261
-
-
Bogman, K.1
Erne-Brand, F.2
Alsenz, J.3
Drewe, J.4
-
20
-
-
0037432169
-
Involvement of cholesterol in the inhibitory effect of dimethyl-beta-cyclodextrin on P-glycoprotein and MRP2 function in Caco-2 cells
-
Yunomae K., Arima H., Hirayama F., and Uekama K. Involvement of cholesterol in the inhibitory effect of dimethyl-beta-cyclodextrin on P-glycoprotein and MRP2 function in Caco-2 cells. FEBS Lett. 536 (2003) 225-231
-
(2003)
FEBS Lett.
, vol.536
, pp. 225-231
-
-
Yunomae, K.1
Arima, H.2
Hirayama, F.3
Uekama, K.4
-
21
-
-
33846557371
-
Modulation of drug-stimulated ATPase activity of human MDR1/P-glycoprotein by cholesterol
-
Kimura Y., Kioka N., Kato H., Matsuo M., and Ueda K. Modulation of drug-stimulated ATPase activity of human MDR1/P-glycoprotein by cholesterol. Biochem. J. 401 (2007) 597-605
-
(2007)
Biochem. J.
, vol.401
, pp. 597-605
-
-
Kimura, Y.1
Kioka, N.2
Kato, H.3
Matsuo, M.4
Ueda, K.5
-
22
-
-
38349112838
-
Cholesterol fill-in model: mechanism for substrate recognition by ABC proteins
-
Kimura Y., Kodan A., Matsuo M., and Ueda K. Cholesterol fill-in model: mechanism for substrate recognition by ABC proteins. J. Bioenerg. Biomembr. 39 (2007) 447-452
-
(2007)
J. Bioenerg. Biomembr.
, vol.39
, pp. 447-452
-
-
Kimura, Y.1
Kodan, A.2
Matsuo, M.3
Ueda, K.4
-
23
-
-
0038480045
-
Structure-activity relationship: analyses of p-glycoprotein substrates and inhibitors
-
Wang R.B., Kuo C.L., Lien L.L., and Lien E.J. Structure-activity relationship: analyses of p-glycoprotein substrates and inhibitors. J. Clin. Pharm. Ther. 28 (2003) 203-228
-
(2003)
J. Clin. Pharm. Ther.
, vol.28
, pp. 203-228
-
-
Wang, R.B.1
Kuo, C.L.2
Lien, L.L.3
Lien, E.J.4
-
24
-
-
0030971840
-
Structure of the multidrug resistance P-glycoprotein to 2.5 nm resolution determined by electron microscopy and image analysis
-
Rosenberg M.F., Callaghan R., Ford R.C., and Higgins C.F. Structure of the multidrug resistance P-glycoprotein to 2.5 nm resolution determined by electron microscopy and image analysis. J. Biol. Chem. 272 (1997) 10685-10694
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 10685-10694
-
-
Rosenberg, M.F.1
Callaghan, R.2
Ford, R.C.3
Higgins, C.F.4
-
25
-
-
17544368685
-
Multidrug resistance proteins: role of P-glycoprotein, MRP1, MRP2, and BCRP (ABCG2) in tissue defense
-
Leslie E.M., Deeley R.G., and Cole S.P. Multidrug resistance proteins: role of P-glycoprotein, MRP1, MRP2, and BCRP (ABCG2) in tissue defense. Toxicol. Appl. Pharmacol. 204 (2005) 216-237
-
(2005)
Toxicol. Appl. Pharmacol.
, vol.204
, pp. 216-237
-
-
Leslie, E.M.1
Deeley, R.G.2
Cole, S.P.3
-
26
-
-
0035028211
-
Charged amino acids in the transmembrane domains are involved in the determination of the substrate specificity of rat Mrp2
-
Ito K., Suzuki H., and Sugiyama Y. Charged amino acids in the transmembrane domains are involved in the determination of the substrate specificity of rat Mrp2. Mol. Pharmacol. 59 (2001) 1077-1085
-
(2001)
Mol. Pharmacol.
, vol.59
, pp. 1077-1085
-
-
Ito, K.1
Suzuki, H.2
Sugiyama, Y.3
-
27
-
-
0034786153
-
Single amino acid substitution of rat MRP2 results in acquired transport activity for taurocholate
-
Ito K., Suzuki H., and Sugiyama Y. Single amino acid substitution of rat MRP2 results in acquired transport activity for taurocholate. Am. J. Physiol. Gastrointest. Liver Physiol. 281 (2001) G1034-1043
-
(2001)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.281
-
-
Ito, K.1
Suzuki, H.2
Sugiyama, Y.3
-
28
-
-
0034671544
-
Identification of basic residues involved in drug export function of human multidrug resistance-associated protein 2
-
Ryu S., Kawabe T., Nada S., and Yamaguchi A. Identification of basic residues involved in drug export function of human multidrug resistance-associated protein 2. J. Biol. Chem. 275 (2000) 39617-39624
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 39617-39624
-
-
Ryu, S.1
Kawabe, T.2
Nada, S.3
Yamaguchi, A.4
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