Identification of the transcription initiation site reveals a novel transcript structure for Plasmodium falciparum maebl

Experimental Parasitology

Volumn 121, Issue 1, 2009, Pages 110-114

  Balu, Bharath ^a   Blair, Peter L ^b   Adams, John H ^a  

^a NATIONAL SCHOOL OF PUBLIC HEALTH   (United States)

^b EARLHAM COLLEGE   (United States)

Author keywords

Bicistronic mRNA; Gene regulation; maebl; Malaria; Plasmodium falciparum; Promoter

Indexed keywords

PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE;

5' UNTRANSLATED REGION; ARTICLE; ERYTHROCYTE; GENE CONTROL; LIFE CYCLE; MAEBL GENE; NONHUMAN; NORTHERN BLOTTING; OPEN READING FRAME; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; PROMOTER REGION; PROTOZOAL GENETICS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSCRIPTION INITIATION;

ANIMALS; BLOTTING, NORTHERN; CLONING, MOLECULAR; DNA PRIMERS; DNA, PROTOZOAN; ERYTHROCYTES; HUMANS; PLASMODIUM FALCIPARUM; POLYMERASE CHAIN REACTION; PROMOTER REGIONS, GENETIC; PROTOZOAN PROTEINS; RANDOM AMPLIFIED POLYMORPHIC DNA TECHNIQUE; RECEPTORS, CELL SURFACE; RNA, PROTOZOAN; TRANSCRIPTION, GENETIC;

EUKARYOTA; PLASMODIUM (APICOMPLEXA); PLASMODIUM FALCIPARUM;

EID: 57049180712     PISSN: 00144894     EISSN: 10902449     Source Type: Journal    
DOI: 10.1016/j.exppara.2008.10.003     Document Type: Article

References (24)

1. Balu B., and Adams J.H. Fluorescent chloramphenicol as a substitute for radioactive [14C]-chloramphenicol for CAT reporter assays in Plasmodium falciparum. Molecular and Biochemical Parasitology 126 (2003) 285-286
2. Balu B., Shoue D.A., Fraser Jr. M.J., and Adams J.H. High-efficiency transformation of Plasmodium falciparum by the lepidopteran transposable element piggyBac. Proceedings of the National Academy of Sciences of the United States of America 102 (2005) 16391-16396
3. Blair P.L., Witney A., Haynes J.D., Moch J.K., Carucci D.J., and Adams J.H. Transcripts of developmentally regulated Plasmodium falciparum genes quantified by real-time RT-PCR. Nucleic Acids Research 30 (2002) 2224-2231
4. Bozdech, Z., Llinas, M., Pulliam, B. L., Wong, E. D., Zhu, J., DeRisi, J. L., 2003. The transcriptome of the intraerythrocytic developmental cycle of Plasmodium falciparum. PLoS Biology 1 (1), e5, doi:10.1371/journal.pbio.0000005.
5. Crabb B.S., and Cowman A.F. Characterization of promoters and stable transfection by homologous and nonhomologous recombination in Plasmodium falciparum. Proceedings of the National Academy of Sciences of the United States of America 93 (1996) 7289-7294
6. De Silva E.K., Gehrke A.R., Olszewski K., Leon I., Chahal J.S., Bulyk M.L., and Llinas M. Specific DNA-binding by apicomplexan AP2 transcription factors. Proceedings of the National Academy of Sciences of the United States of America 105 (2008) 8393-8398
7. Hori R., and Firtel R.A. Identification and characterization of multiple A/T-rich cis-acting elements that control expression from Dictyostelium actin promoters: the Dictyostelium actin upstream activating sequence confers growth phase expression and has enhancer-like properties. Nucleic Acids Research 22 (1994) 5099-5111
8. Horrocks P., Dechering K., and Lanzer M. Control of gene expression in Plasmodium falciparum. Molecular and Biochemical Parasitology 95b (1998) 171-181
9. Kappe S.H., Noe A.R., Fraser T.S., Blair P.L., and Adams J.H. A family of chimeric erythrocyte binding proteins of malaria parasites. Proceedings of the National Academy of Sciences of the United States of America 95 (1998) 1230-1235
10. Kissinger J.C., Brunk B.P., Crabtree J., Fraunholz M.J., Gajria B., Milgram A.J., Pearson D.S., Schug J., Bahl A., Diskin S.J., Ginsburg H., Grant G.R., Gupta D., Labo P., Li L., Mailman M.D., McWeeney S.K., Whetzel P., Stoeckert C.J., and Roos D.S. The Plasmodium genome database. Nature 419 (2002) 490-492
11. Kozak M. Effects of intercistronic length on the efficiency of reinitiation by eucaryotic ribosomes. Molecular and Cellular Biology 7 (1987) 3438-3445
12. Le Roch K.G., Zhou Y., Blair P.L., Grainger M., Moch J.K., Haynes J.D., De La Vega P., Holder A.A., Batalov S., Carucci D.J., and Winzeler E.A. Discovery of gene function by expression profiling of the malaria parasite life cycle. Science 301 (2003) 1503-1508
13. Militello K.T., Dodge M., Bethke L., and Wirth D.F. Identification of regulatory elements in the Plasmodium falciparum genome. Molecular and Biochemical Parasitology 134 (2004) 75-88
14. Myrick A., Munasinghe A., Patankar S., and Wirth D.F. Mapping of the Plasmodium falciparum multidrug resistance gene 5′-upstream region, and evidence of induction of transcript levels by antimalarial drugs in chloroquine sensitive parasites. Molecular Microbiology 49 (2003) 671-683
15. Porter M.E. The DNA polymerase delta promoter from Plasmodium falciparum contains an unusually long 5′ untranslated region and intrinsic DNA curvature. Molecular and Biochemical Parasitology 114 (2001) 249-255
16. Saenz F.E., Balu B., Smith J., Mendonca S.R., and Adams J.H. The transmembrane isoform of Plasmodium falciparum MAEBL is essential for the invasion of Anopheles salivary glands. PLoS ONE 3 (2008) e2287
17. Singh N., Preiser P., Renia L., Balu B., Barnwell J., Blair P., Jarra W., Voza T., Landau I., and Adams J.H. Conservation and developmental control of alternative splicing in maebl among malaria parasites. Journal of Molecular Biology 343 (2004) 589-599
18. Stallings R.L. Distribution of trinucleotide microsatellites in different categories of mammalian genomic sequence: implications for human genetic diseases. Genomics 21 (1994) 116-121
19. Struhl K. Naturally occurring poly(dA-dT) sequences are upstream promoter elements for constitutive transcription in yeast. Proceedings of the National Academy of Sciences of the United States of America 82 (1985) 8419-8423
20. Trotta E., Del Grosso N., Erba M., and Paci M. The ATT strand of AAT.ATT trinucleotide repeats adopts stable hairpin structures induced by minor groove binding ligands. Biochemistry 39 (2000) 6799-6808
21. Winter E., and Varshavsky A. A DNA binding protein that recognizes oligo(dA).oligo(dT) tracts. EMBO Journal 8 (1989) 1867-1877
22. Wu J., Sieglaff D.H., Gervin J., and Xie X.S. Discovering regulatory motifs in the Plasmodium genome using comparative genomics. Bioinformatics (2008)
23. Wu Y., Sifri C.D., Lei H.H., Su X.Z., and Wellems T.E. Transfection of Plasmodium falciparum within human red blood cells. Proceedings of the National Academy of Sciences of the United States of America 92 (1995) 973-977
24. Young J.A., Johnson J.R., Benner C., Yan S.F., Chen K., Le Roch K.G., Zhou Y., and Winzeler E.A. In silico discovery of transcription regulatory elements in Plasmodium falciparum. BMC Genomics 9 (2008) 70