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Volumn 29, Issue , 2007, Pages 37-46

A new mechanism for aging: Chemical "age spots" in immortal DNA strands in distributed stem cells

Author keywords

Adult stem cells; Asymmetric self renewal; Co segregation; Distributed stem cells; Immortal DNA strands; Mitosis; Non random

Indexed keywords

ARTICLE; CANCER INCIDENCE; CELL AGING; CELL IMMORTALIZATION; CELL RENEWAL; CELLULAR DISTRIBUTION; CHEMICAL MODIFICATION; CHROMOSOME SEGREGATION; DECOMPOSITION; DNA STRAND; FIBROBLAST CULTURE; HUMAN; MAMMAL CELL; MITOSIS; MUTATION RATE; NONHUMAN; PHENOTYPE; PLANT ROOT; PREDICTION; PRIORITY JOURNAL; REJUVENATION; ROOT CELL; STEM CELL; TURNOVER TIME;

EID: 57049122758     PISSN: 08886008     EISSN: None     Source Type: Journal    
DOI: 10.3233/bd-2008-29105     Document Type: Article
Times cited : (15)

References (51)
  • 1
    • 34548841127 scopus 로고    scopus 로고
    • From stem to stem
    • A. Brunet and T. A. Rando, From stem to stem, Nature 449 (2007), 288-291.
    • (2007) Nature , vol.449 , pp. 288-291
    • Brunet, A.1    Rando, T.A.2
  • 2
    • 0026873214 scopus 로고
    • Stem cell regulation, tissue ontogeny, and oncogenic events
    • A.G. Knudson, Stem cell regulation, tissue ontogeny, and oncogenic events, Seminars in Cancer Biology 3 (1992), 99-106.
    • (1992) Seminars in Cancer Biology , vol.3 , pp. 99-106
    • Knudson, A.G.1
  • 3
    • 33751208596 scopus 로고    scopus 로고
    • The key role of adult stem cells: Therapeutic perspectives
    • A. Pessina and L. Gribaldo, The key role of adult stem cells: therapeutic perspectives, Current Medical Research Opinions 22 (2006), 2287-2300.
    • (2006) Current Medical Research Opinions , vol.22 , pp. 2287-2300
    • Pessina, A.1    Gribaldo, L.2
  • 7
    • 0036591968 scopus 로고    scopus 로고
    • Intestinal stem cells protect their genome by selective segregation of template DNA strands
    • C.S. Potten, G. Owen and D. Booth, Intestinal stem cells protect their genome by selective segregation of template DNA strands, Journal of Cell Science 115 (2002), 2381-2388.
    • (2002) Journal of Cell Science , vol.115 , pp. 2381-2388
    • Potten, C.S.1    Owen, G.2    Booth, D.3
  • 8
    • 0018034237 scopus 로고
    • The segregation of DNA in epithelial stem cells
    • C.S. Potten, W.J. Hume, P. Reid and J. Cairns, The segregation of DNA in epithelial stem cells, Cell 15 (1978), 899-906.
    • (1978) Cell , vol.15 , pp. 899-906
    • Potten, C.S.1    Hume, W.J.2    Reid, P.3    Cairns, J.4
  • 10
    • 34250007142 scopus 로고    scopus 로고
    • Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age
    • D.J. Rossi, D. Bryder, J. Seita, A. Nussenzweig, J. Hoeijmakers and I.L. Weissman, Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age, Nature 447 (2007), 725-730.
    • (2007) Nature , vol.447 , pp. 725-730
    • Rossi, D.J.1    Bryder, D.2    Seita, J.3    Nussenzweig, A.4    Hoeijmakers, J.5    Weissman, I.L.6
  • 11
    • 36249020339 scopus 로고    scopus 로고
    • Aging and the germ line: Where mortality and immortality meet
    • D.L. Jones, Aging and the germ line: Where mortality and immortality meet, Stem Cell Reviews 3 (2007), 192-200.
    • (2007) Stem Cell Reviews , vol.3 , pp. 192-200
    • Jones, D.L.1
  • 13
    • 13244287677 scopus 로고    scopus 로고
    • Mechanisms of hair graying: Incomplete melanocyte stem cell maintenance in the niche
    • E.K. Nishimura, S.R. Granter and D.E. Fisher, Mechanisms of hair graying: Incomplete melanocyte stem cell maintenance in the niche, Science 307 (2005), 720-724.
    • (2005) Science , vol.307 , pp. 720-724
    • Nishimura, E.K.1    Granter, S.R.2    Fisher, D.E.3
  • 14
    • 0030980593 scopus 로고    scopus 로고
    • Genetic control of cell division patterns in developing plants
    • E.M. Meyerowitz, Genetic control of cell division patterns in developing plants, Cell 88 (1997), 299-308.
    • (1997) Cell , vol.88 , pp. 299-308
    • Meyerowitz, E.M.1
  • 15
    • 0036007425 scopus 로고    scopus 로고
    • The intestinal epithelial stem cell
    • E. Marshman, C. Booth and C.S. Potten, The intestinal epithelial stem cell, Bioessays 24 (2002), 91-98.
    • (2002) Bioessays , vol.24 , pp. 91-98
    • Marshman, E.1    Booth, C.2    Potten, C.S.3
  • 16
    • 17044364797 scopus 로고    scopus 로고
    • Melanocyte stem cell maintenance and hair graying
    • E. Steingrimsson, N.G. Copeland and N.A. Jenkins, Melanocyte stem cell maintenance and hair graying, Cell 121 (2005) 9-12.
    • (2005) Cell , vol.121 , pp. 9-12
    • Steingrimsson, E.1    Copeland, N.G.2    Jenkins, N.A.3
  • 17
    • 37649028095 scopus 로고    scopus 로고
    • Evolutionary dynamics of adult stem cells: Comparison of random and immortal-strand segregation mechanisms
    • E. Tannenbaum, J.L. Sherley and E.I. Shakhnovich, Evolutionary dynamics of adult stem cells: Comparison of random and immortal-strand segregation mechanisms, Physical Review E 71 (2005), 041914-1-101914-9.
    • (2005) Physical Review E , vol.71
    • Tannenbaum, E.1    Sherley, J.L.2    Shakhnovich, E.I.3
  • 18
    • 14844343185 scopus 로고    scopus 로고
    • Label-retaining epithelial cells in mouse mammary gland divide asymmetrically and retain their template DNA strands
    • G. Smith, Label-retaining epithelial cells in mouse mammary gland divide asymmetrically and retain their template DNA strands, Development 132 (2005), 681-687.
    • (2005) Development , vol.132 , pp. 681-687
    • Smith, G.1
  • 23
    • 0016692602 scopus 로고
    • Mutation selection and the natural history of cancer
    • J. Cairns, Mutation selection and the natural history of cancer, Nature 255 (1975), 197-200.
    • (1975) Nature , vol.255 , pp. 197-200
    • Cairns, J.1
  • 25
    • 84967389310 scopus 로고    scopus 로고
    • Asymmetric self-renewal: The mark of the adult stem cell
    • N.A. Habib, M.Y. Gordon, N. Levicar, L. Jiao and G. Thomas-Black, eds, Imperial College Press, London
    • J.L. Sherley, Asymmetric self-renewal: The mark of the adult stem cell, in: Stem Cell Repair and Regeneration, N.A. Habib, M.Y. Gordon, N. Levicar, L. Jiao and G. Thomas-Black, eds, Imperial College Press, London, 2005, pp. 21-28.
    • (2005) Stem Cell Repair and Regeneration , pp. 21-28
    • Sherley, J.L.1
  • 26
    • 84986558327 scopus 로고    scopus 로고
    • Mechanisms of genetic fidelity in mammalian adult stem cells
    • C.S. Potten, R.B. Clarke, J. Wilson and A.G. Renehan, eds, Taylor Francis, New York
    • J.L. Sherley, Mechanisms of genetic fidelity in mammalian adult stem cells, in: Tissue Stem Cells, C.S. Potten, R.B. Clarke, J. Wilson and A.G. Renehan, eds, Taylor Francis, New York, 2006, pp. 37-54.
    • (2006) Tissue Stem Cells , pp. 37-54
    • Sherley, J.L.1
  • 27
    • 0028961442 scopus 로고
    • Expression of the wild-type p53 antioncogene induces guanine nucleotide-dependent stem cell division kinetics
    • J.L. Sherley, P.B. Stadler and D.R. Johnson, Expression of the wild-type p53 antioncogene induces guanine nucleotide-dependent stem cell division kinetics, Proceedings of the National Academy of Science USA 92 (1995), 136-140.
    • (1995) Proceedings of the National Academy of Science USA , vol.92 , pp. 136-140
    • Sherley, J.L.1    Stadler, P.B.2    Johnson, D.R.3
  • 28
    • 0036894521 scopus 로고    scopus 로고
    • Co-segregation of chromosomes containing immortal DNA strands in cells that cycle with asymmetric stem cell kinetics
    • J.R. Merok, J.A. Lansita, J.R. Tunstead and J.L. Sherley, Co-segregation of chromosomes containing immortal DNA strands in cells that cycle with asymmetric stem cell kinetics, Cancer Research 62 (2002), 6791-6795.
    • (2002) Cancer Research , vol.62 , pp. 6791-6795
    • Merok, J.R.1    Lansita, J.A.2    Tunstead, J.R.3    Sherley, J.L.4
  • 30
    • 33750390911 scopus 로고    scopus 로고
    • Alternative sources of adult stem cells: A possible solution to the embryonic stem cell debate
    • K.E. Moore, J.F. Mills and M.M. Thornton, Alternative sources of adult stem cells: A possible solution to the embryonic stem cell debate, Gender Medicine 3 (2007), 161-168.
    • (2007) Gender Medicine , vol.3 , pp. 161-168
    • Moore, K.E.1    Mills, J.F.2    Thornton, M.M.3
  • 31
    • 57049111424 scopus 로고
    • Nonrandom segregation of sister chromatids
    • H.J. Teas, ed, University of Kentucky Press, Lexington
    • K.G. Lark, Nonrandom segregation of sister chromatids, in: Genetics & Developmental Biology, H.J. Teas, ed., University of Kentucky Press, Lexington, 1969, pp. 8-24.
    • (1969) Genetics & Developmental Biology , pp. 8-24
    • Lark, K.G.1
  • 32
    • 0014106493 scopus 로고
    • Nonrandom segregation of sister chromatids in Vicia faba and Triticum boeoticum
    • K.G. Lark, Nonrandom segregation of sister chromatids in Vicia faba and Triticum boeoticum, Proceedings of the National Academy of Science USA 58 (1967), 352-359.
    • (1967) Proceedings of the National Academy of Science USA , vol.58 , pp. 352-359
    • Lark, K.G.1
  • 33
    • 0014004452 scopus 로고
    • Segregation of sister chromatids in mammalian cells
    • K.G. Lark, R.A. Consigli and H.C. Minocha, Segregation of sister chromatids in mammalian cells, Science 154 (1966), 1202-1205.
    • (1966) Science , vol.154 , pp. 1202-1205
    • Lark, K.G.1    Consigli, R.A.2    Minocha, H.C.3
  • 35
    • 36248979768 scopus 로고    scopus 로고
    • Aging, graying and loss of melanocyte stem cells
    • K.Y. Sarin and S.E. Artandi, Aging, graying and loss of melanocyte stem cells, Stem Cell Reviews 3 (2007), 212-217.
    • (2007) Stem Cell Reviews , vol.3 , pp. 212-217
    • Sarin, K.Y.1    Artandi, S.E.2
  • 36
    • 0025773554 scopus 로고
    • Mutator phenotype may be required for multistage carcinogenesis
    • L.A. Loeb, Mutator phenotype may be required for multistage carcinogenesis, Cancer Research 51 (1991), 3075-3079.
    • (1991) Cancer Research , vol.51 , pp. 3075-3079
    • Loeb, L.A.1
  • 39
    • 17144373352 scopus 로고    scopus 로고
    • Immortal DNA strand co-segregation requires p53/IMPDH-Dependent asymmetric self-renewal associated with adult stem cells
    • L. Rambhatla, S. Ram-Mohan, J.J. Cheng and J.L. Sherley, Immortal DNA strand co-segregation requires p53/IMPDH-Dependent asymmetric self-renewal associated with adult stem cells, Cancer Research 65 (2005), 3155-3161.
    • (2005) Cancer Research , vol.65 , pp. 3155-3161
    • Rambhatla, L.1    Ram-Mohan, S.2    Cheng, J.J.3    Sherley, J.L.4
  • 40
    • 34249056493 scopus 로고    scopus 로고
    • High incidence of non-random template strand segregation and asymmetric fate determination in dividing stem cell's and their progeny
    • M.J. Conboy, A.O. Karasov and T.A. Rando, High incidence of non-random template strand segregation and asymmetric fate determination in dividing stem cell's and their progeny, Public Library of Science Biology 5 (2007), 1120-1126.
    • (2007) Public Library of Science Biology , vol.5 , pp. 1120-1126
    • Conboy, M.J.1    Karasov, A.O.2    Rando, T.A.3
  • 41
    • 0003037004 scopus 로고    scopus 로고
    • Stem cells and cellular pedigrees - a conceptual introduction
    • C.S. Potten, ed, Academic Press, London
    • M. Loeffler and C.S. Potten, Stem cells and cellular pedigrees - a conceptual introduction, in: Stem Cells, C.S. Potten, ed., Academic Press, London, 1997, pp. 1-27.
    • (1997) Stem Cells , pp. 1-27
    • Loeffler, M.1    Potten, C.S.2
  • 42
    • 33644560281 scopus 로고    scopus 로고
    • Cancer stem cells: An old idea - a paradigm shift
    • M.S. Wicha, S. Liu and G. Dontu, Cancer stem cells: An old idea - a paradigm shift," Cancer Research 66 (2006), 1883-1890.
    • (2006) Cancer Research , vol.66 , pp. 1883-1890
    • Wicha, M.S.1    Liu, S.2    Dontu, G.3
  • 43
    • 0141740426 scopus 로고    scopus 로고
    • Focusing on foci: H2AX and the recruitment of DNA-damage response factors
    • O. Fernandez-Capitello, A. Celeste and A. Nussenzweig, Focusing on foci: H2AX and the recruitment of DNA-damage response factors, Cell Cycle 2 (2003), 426-427.
    • (2003) Cell Cycle , vol.2 , pp. 426-427
    • Fernandez-Capitello, O.1    Celeste, A.2    Nussenzweig, A.3
  • 46
    • 1542374198 scopus 로고    scopus 로고
    • Problems of somatic mutation and cancer
    • S.A. Frank and M.A. Nowak, Problems of somatic mutation and cancer, BioEssays 26 (2004), 291-299.
    • (2004) BioEssays , vol.26 , pp. 291-299
    • Frank, S.A.1    Nowak, M.A.2
  • 47
    • 33745614062 scopus 로고    scopus 로고
    • Stem cells, ageing and the quest for immortality
    • T.A. Rando, Stem cells, ageing and the quest for immortality, Nature 441 (2006), 1080-1086.
    • (2006) Nature , vol.441 , pp. 1080-1086
    • Rando, T.A.1
  • 48
    • 0027278557 scopus 로고
    • Instability and decay of the primary structure of DNA
    • T. Lindahl, Instability and decay of the primary structure of DNA, Nature 362 (1993), 709-715.
    • (1993) Nature , vol.362 , pp. 709-715
    • Lindahl, T.1
  • 51
    • 0037716639 scopus 로고    scopus 로고
    • Have environmental ramagens caused oncomutations in people?
    • W.G. Thilly, Have environmental ramagens caused oncomutations in people? Nature Genetics 34 (2003), 255-259.
    • (2003) Nature Genetics , vol.34 , pp. 255-259
    • Thilly, W.G.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.