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Volumn 86, Issue 13, 2008, Pages 3018-3027

Protective effects of erythropoietin on tau phosphorylation induced by β-amyloid

Author keywords

amyloid peptide; Alzheimer's disease; Erythropoietin; Tau phosphorylation

Indexed keywords

AMYLOID BETA PROTEIN; ERYTHROPOIETIN; GLYCOGEN SYNTHASE KINASE 3BETA; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; TAU PROTEIN;

EID: 57049090468     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.21745     Document Type: Article
Times cited : (53)

References (81)
  • 1
    • 0032859938 scopus 로고    scopus 로고
    • Inhibition of tau phosphorylating protein kinase cdk5 prevents beta-amyloid-induced neuronal death
    • Alvarez A, Toro R, Caceres A, Maccioni RB. 1999. Inhibition of tau phosphorylating protein kinase cdk5 prevents beta-amyloid-induced neuronal death. FEBS Lett 459:421-426.
    • (1999) FEBS Lett , vol.459 , pp. 421-426
    • Alvarez, A.1    Toro, R.2    Caceres, A.3    Maccioni, R.B.4
  • 2
    • 0036276050 scopus 로고    scopus 로고
    • Regulation of tau phosphorylation and protection against beta-amyloid-induced neurodegeneration by lithium. Possible implications for Alzheimer's disease
    • Alvarez G, Munoz-Montano JR, Satrustegui J, Avila J, Bogonez E, Diaz-Nido J. 2002. Regulation of tau phosphorylation and protection against beta-amyloid-induced neurodegeneration by lithium. Possible implications for Alzheimer's disease. Bipolar Disord 4:153-165.
    • (2002) Bipolar Disord , vol.4 , pp. 153-165
    • Alvarez, G.1    Munoz-Montano, J.R.2    Satrustegui, J.3    Avila, J.4    Bogonez, E.5    Diaz-Nido, J.6
  • 3
    • 0033151527 scopus 로고    scopus 로고
    • Protein kinase B (c-Akt), phosphatidylinositol 3-kinase, and STAT5 are activated by erythropoietin (EPO) in HCD57 erythroid cells but are constitutively active in an EPO-independent, apoptosis-resistant subclone (HCD57-SREI cells)
    • Bao H, Jacobs-Helber SM, Lawson AE, Penta K, Wickrema A, Sawyer ST. 1999. Protein kinase B (c-Akt), phosphatidylinositol 3-kinase, and STAT5 are activated by erythropoietin (EPO) in HCD57 erythroid cells but are constitutively active in an EPO-independent, apoptosis-resistant subclone (HCD57-SREI cells). Blood 93:3757-3773.
    • (1999) Blood , vol.93 , pp. 3757-3773
    • Bao, H.1    Jacobs-Helber, S.M.2    Lawson, A.E.3    Penta, K.4    Wickrema, A.5    Sawyer, S.T.6
  • 4
    • 0028233494 scopus 로고
    • Hydrogen peroxide mediates amyloid beta protein toxicity
    • Behl C, Davis JB, Lesley R, Schubert D. 1994. Hydrogen peroxide mediates amyloid beta protein toxicity. Cell 77:817-827.
    • (1994) Cell , vol.77 , pp. 817-827
    • Behl, C.1    Davis, J.B.2    Lesley, R.3    Schubert, D.4
  • 8
    • 0028986916 scopus 로고
    • Beta-amyloid fibrils induce tau phosphorylation and loss of microtubule binding
    • Busciglio J, Lorenzo A, Yeh J, Yankner BA. 1995. Beta-amyloid fibrils induce tau phosphorylation and loss of microtubule binding. Neuron 14:879-888.
    • (1995) Neuron , vol.14 , pp. 879-888
    • Busciglio, J.1    Lorenzo, A.2    Yeh, J.3    Yankner, B.A.4
  • 10
    • 29044433048 scopus 로고    scopus 로고
    • Erythropoietin requires NF-kappaB and its nuclear translocation to prevent early and late apoptotic neuronal injury during beta-amyloid toxicity
    • Chong ZZ, Li F, Maiese K. 2005a. Erythropoietin requires NF-kappaB and its nuclear translocation to prevent early and late apoptotic neuronal injury during beta-amyloid toxicity. Curr Neurovasc Res 2:387-399.
    • (2005) Curr Neurovasc Res , vol.2 , pp. 387-399
    • Chong, Z.Z.1    Li, F.2    Maiese, K.3
  • 11
    • 20444399515 scopus 로고    scopus 로고
    • Stress in the brain: Novel cellular mechanisms of injury linked to Alzheimer's disease
    • Chong ZZ, Li F, Maiese K. 2005b. Stress in the brain: novel cellular mechanisms of injury linked to Alzheimer's disease. Brain Res Brain Res Rev 49:1-21.
    • (2005) Brain Res Brain Res Rev , vol.49 , pp. 1-21
    • Chong, Z.Z.1    Li, F.2    Maiese, K.3
  • 12
    • 3242733091 scopus 로고    scopus 로고
    • Age-related changes in erythropoietin immunoreactivity in the cerebral cortex and hippocampus of rats
    • Chung YH, Kim SI, Joo KM, Kim YS, Lee WB, Yun KW, Cha CI. 2004. Age-related changes in erythropoietin immunoreactivity in the cerebral cortex and hippocampus of rats. Brain Res 1018:141-146.
    • (2004) Brain Res , vol.1018 , pp. 141-146
    • Chung, Y.H.1    Kim, S.I.2    Joo, K.M.3    Kim, Y.S.4    Lee, W.B.5    Yun, K.W.6    Cha, C.I.7
  • 13
    • 0029856247 scopus 로고    scopus 로고
    • Early events in erythropoietin-induced signaling
    • Damen JE, Krystal G. 1996. Early events in erythropoietin-induced signaling. Exp Hematol 24:1455-1459.
    • (1996) Exp Hematol , vol.24 , pp. 1455-1459
    • Damen, J.E.1    Krystal, G.2
  • 14
    • 0028785893 scopus 로고
    • Tyrosine 343 in the erythropoietin receptor positively regulates erythropoietin-induced cell proliferation and Stat5 activation
    • Damen JE, Wakao H, Miyajima A, Krosl J, Humphries RK, Cutler RL, Krystal G. 1995. Tyrosine 343 in the erythropoietin receptor positively regulates erythropoietin-induced cell proliferation and Stat5 activation. EMBO J 14:5557-5568.
    • (1995) EMBO J , vol.14 , pp. 5557-5568
    • Damen, J.E.1    Wakao, H.2    Miyajima, A.3    Krosl, J.4    Humphries, R.K.5    Cutler, R.L.6    Krystal, G.7
  • 16
    • 0035833541 scopus 로고    scopus 로고
    • Erythropoietin-mediated neuroprotection involves cross-talk between Jak2 and NF-kappaB signalling cascades
    • Digicaylioglu M, Lipton SA. 2001. Erythropoietin-mediated neuroprotection involves cross-talk between Jak2 and NF-kappaB signalling cascades. Nature 412:641-647.
    • (2001) Nature , vol.412 , pp. 641-647
    • Digicaylioglu, M.1    Lipton, S.A.2
  • 21
    • 0032733910 scopus 로고    scopus 로고
    • Free PKC catalytic subunits (PKM) phosphorylate tau via a pathway distinct from that utilized by intact PKC
    • Ekinci FJ, Shea TB. 1999. Free PKC catalytic subunits (PKM) phosphorylate tau via a pathway distinct from that utilized by intact PKC. Brain Res 850:207-216.
    • (1999) Brain Res , vol.850 , pp. 207-216
    • Ekinci, F.J.1    Shea, T.B.2
  • 22
    • 18744385488 scopus 로고    scopus 로고
    • In vivo activation and nuclear translocation of phosphorylated glycogen synthase kinase-3beta in neuronal apoptosis: Links to tau phosphorylation
    • Elyaman W, Terro F, Wong NS, Hugon J. 2002a. In vivo activation and nuclear translocation of phosphorylated glycogen synthase kinase-3beta in neuronal apoptosis: links to tau phosphorylation. Eur J Neurosci 15:651-660.
    • (2002) Eur J Neurosci , vol.15 , pp. 651-660
    • Elyaman, W.1    Terro, F.2    Wong, N.S.3    Hugon, J.4
  • 23
    • 0036312496 scopus 로고    scopus 로고
    • Involvement of glycogen synthase kinase-3beta and tau phosphorylation in neuronal Golgi disassembly
    • Elyaman W, Yardin C, Hugon J. 2002b. Involvement of glycogen synthase kinase-3beta and tau phosphorylation in neuronal Golgi disassembly. J Neurochem 81:870-880.
    • (2002) J Neurochem , vol.81 , pp. 870-880
    • Elyaman, W.1    Yardin, C.2    Hugon, J.3
  • 24
    • 0141960033 scopus 로고    scopus 로고
    • Beta-amyloid induces paired helical filament-like tau filaments in tissue culture
    • Ferrari A, Hoerndli F, Baechi T, Nitsch RM, Gotz J. 2003. Beta-amyloid induces paired helical filament-like tau filaments in tissue culture. J Biol Chem 278:40162-40168.
    • (2003) J Biol Chem , vol.278 , pp. 40162-40168
    • Ferrari, A.1    Hoerndli, F.2    Baechi, T.3    Nitsch, R.M.4    Gotz, J.5
  • 25
    • 33244474404 scopus 로고    scopus 로고
    • Erythropoietin decreases cytotoxicity and nitric oxide formation induced by inflammatory stimuli in rat oligodendrocytes
    • Genc K, Genc S, Baskin H, Semin I. 2006. Erythropoietin decreases cytotoxicity and nitric oxide formation induced by inflammatory stimuli in rat oligodendrocytes. Physiol Res Acad Sci Bohemoslovaca 55:33-38.
    • (2006) Physiol Res Acad Sci Bohemoslovaca , vol.55 , pp. 33-38
    • Genc, K.1    Genc, S.2    Baskin, H.3    Semin, I.4
  • 27
    • 0026487365 scopus 로고
    • Glycogen synthase kinase-3 induces Alzheimer's disease-like phosphorylation of tau: Generation of paired helical filament epitopes and neuronal localisation of the kinase
    • Hanger DP, Hughes K, Woodgett JR, Brion JP, Anderton BH. 1992. Glycogen synthase kinase-3 induces Alzheimer's disease-like phosphorylation of tau: generation of paired helical filament epitopes and neuronal localisation of the kinase. Neurosci Lett 147:58-62.
    • (1992) Neurosci Lett , vol.147 , pp. 58-62
    • Hanger, D.P.1    Hughes, K.2    Woodgett, J.R.3    Brion, J.P.4    Anderton, B.H.5
  • 28
    • 0343570105 scopus 로고    scopus 로고
    • Modulation of beta-amyloid precursor protein processing and tau phosphorylation by acetylcholine receptors
    • Hellstrom-Lindahl E. 2000. Modulation of beta-amyloid precursor protein processing and tau phosphorylation by acetylcholine receptors. Eur J Pharmacol 393:255-263.
    • (2000) Eur J Pharmacol , vol.393 , pp. 255-263
    • Hellstrom-Lindahl, E.1
  • 29
    • 0042425738 scopus 로고    scopus 로고
    • Co-localization of glycogen synthase kinase-3 with neuro.brillary tangles and granulovacuolar degeneration in transgenic mice
    • Ishizawa T, Sahara N, Ishiguro K, Kersh J, McGowan E, Lewis J, Hutton M, Dickson DW, Yen SH. 2003. Co-localization of glycogen synthase kinase-3 with neuro.brillary tangles and granulovacuolar degeneration in transgenic mice. Am J Pathol 163:1057-1067.
    • (2003) Am J Pathol , vol.163 , pp. 1057-1067
    • Ishizawa, T.1    Sahara, N.2    Ishiguro, K.3    Kersh, J.4    McGowan, E.5    Lewis, J.6    Hutton, M.7    Dickson, D.W.8    Yen, S.H.9
  • 31
    • 0034153934 scopus 로고    scopus 로고
    • Alzheimer's disease: Basic aspects]
    • Iwatsubo T. 2000. [Alzheimer's disease: basic aspects]. Nippon Ronen Igakkai Zasshi 37:207-211.
    • (2000) Nippon Ronen Igakkai Zasshi , vol.37 , pp. 207-211
    • Iwatsubo, T.1
  • 32
    • 2942623972 scopus 로고    scopus 로고
    • The retinoic acid and brain-derived neurotrophic factor differentiated SH-SY5Y cell line as a model for Alzheimer's disease-like tau phosphorylation
    • Jamsa A, Hasslund K, Cowburn RF, Backstrom A, Vasange M. 2004. The retinoic acid and brain-derived neurotrophic factor differentiated SH-SY5Y cell line as a model for Alzheimer's disease-like tau phosphorylation. Biochem Biophys Res Commun 319:993-1000.
    • (2004) Biochem Biophys Res Commun , vol.319 , pp. 993-1000
    • Jamsa, A.1    Hasslund, K.2    Cowburn, R.F.3    Backstrom, A.4    Vasange, M.5
  • 33
    • 0030966371 scopus 로고    scopus 로고
    • Mitogenic signaling and inhibition of apoptosis via the erythropoietin receptor Box-1 domain
    • Joneja B, Wojchowski DM. 1997. Mitogenic signaling and inhibition of apoptosis via the erythropoietin receptor Box-1 domain. J Biol Chem 272:11176-11184.
    • (1997) J Biol Chem , vol.272 , pp. 11176-11184
    • Joneja, B.1    Wojchowski, D.M.2
  • 34
    • 0031893945 scopus 로고    scopus 로고
    • Erythropoietin and erythropoietin receptor in the developing human central nervous system
    • Juul SE, Anderson DK, Li Y, Christensen RD. 1998. Erythropoietin and erythropoietin receptor in the developing human central nervous system. Pediatr Res 43:40-49.
    • (1998) Pediatr Res , vol.43 , pp. 40-49
    • Juul, S.E.1    Anderson, D.K.2    Li, Y.3    Christensen, R.D.4
  • 35
    • 0027232014 scopus 로고
    • Trophic effect of erythropoietin and other hematopoietic factors on central cholinergic neurons in vitro and in vivo
    • Konishi Y, Chui DH, Hirose H, Kunishita T, Tabira T. 1993. Trophic effect of erythropoietin and other hematopoietic factors on central cholinergic neurons in vitro and in vivo. Brain Res 609:29-35.
    • (1993) Brain Res , vol.609 , pp. 29-35
    • Konishi, Y.1    Chui, D.H.2    Hirose, H.3    Kunishita, T.4    Tabira, T.5
  • 37
    • 33745677648 scopus 로고    scopus 로고
    • Comparative study of endoplasmic reticulum stress-induced neuronal death in rat cultured hippocampal and cerebellar granule neurons
    • Kosuge Y, Sakikubo T, Ishige K, Ito Y. 2006. Comparative study of endoplasmic reticulum stress-induced neuronal death in rat cultured hippocampal and cerebellar granule neurons. Neurochem Int 49:285-293.
    • (2006) Neurochem Int , vol.49 , pp. 285-293
    • Kosuge, Y.1    Sakikubo, T.2    Ishige, K.3    Ito, Y.4
  • 38
    • 0037109201 scopus 로고    scopus 로고
    • Amyloid beta-peptide alters the distribution of early endosomes and inhibits phosphorylation of Akt in the presence of 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT)
    • Kubo T, Nishimura S, Oda T. 2002. Amyloid beta-peptide alters the distribution of early endosomes and inhibits phosphorylation of Akt in the presence of 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT). Brain Res 106:94-100.
    • (2002) Brain Res , vol.106 , pp. 94-100
    • Kubo, T.1    Nishimura, S.2    Oda, T.3
  • 39
    • 0342646961 scopus 로고    scopus 로고
    • Recombinant erythropoietin in urine
    • Lasne F, de Ceaurriz J. 2000. Recombinant erythropoietin in urine. Nature 405:635.
    • (2000) Nature , vol.405 , pp. 635
    • Lasne, F.1    de Ceaurriz, J.2
  • 43
    • 0942265972 scopus 로고    scopus 로고
    • Amyloid-beta-induced toxicity of primary neurons is dependent upon differentiation-associated increases in tau and cyclin-dependent kinase 5 expression
    • Liu T, Perry G, Chan HW, Verdile G, Martins RN, Smith MA, Atwood CS. 2004. Amyloid-beta-induced toxicity of primary neurons is dependent upon differentiation-associated increases in tau and cyclin-dependent kinase 5 expression. J Neurochem 88:554-563.
    • (2004) J Neurochem , vol.88 , pp. 554-563
    • Liu, T.1    Perry, G.2    Chan, H.W.3    Verdile, G.4    Martins, R.N.5    Smith, M.A.6    Atwood, C.S.7
  • 44
    • 12844250694 scopus 로고    scopus 로고
    • Induction of hyperphosphorylated tau in primary rat cortical neuron cultures mediated by oxidative stress and glycogen synthase kinase-3
    • discussion 673-681
    • Lovell MA, Xiong S, Xie C, Davies P, Markesbery WR. 2004. Induction of hyperphosphorylated tau in primary rat cortical neuron cultures mediated by oxidative stress and glycogen synthase kinase-3. J Alzheimers Dis 6:659-671; discussion 673-681.
    • (2004) J Alzheimers Dis , vol.6 , pp. 659-671
    • Lovell, M.A.1    Xiong, S.2    Xie, C.3    Davies, P.4    Markesbery, W.R.5
  • 49
    • 0026091735 scopus 로고
    • Induction of tyrosine phosphorylation by the erythropoietin receptor correlates with mitogenesis
    • Miura O, D'Andrea A, Kabat D, Ihle JN. 1991. Induction of tyrosine phosphorylation by the erythropoietin receptor correlates with mitogenesis. Mol Cell Biol 11:4895-4902.
    • (1991) Mol Cell Biol , vol.11 , pp. 4895-4902
    • Miura, O.1    D'Andrea, A.2    Kabat, D.3    Ihle, J.N.4
  • 50
    • 0026181931 scopus 로고
    • Neuro.brillary tangles, dystrophic neurites (curly fibers), and abnormal phosphorylation of tau
    • Mori H, Ihara Y. 1991. Neuro.brillary tangles, dystrophic neurites (curly fibers), and abnormal phosphorylation of tau. Brain Pathol 1:273-277.
    • (1991) Brain Pathol , vol.1 , pp. 273-277
    • Mori, H.1    Ihara, Y.2
  • 51
    • 17544392900 scopus 로고
    • Phosphorylation of tau by glycogen synthase kinase-3 beta in vitro produces species with similar electrophoretic and immunogenic properties to PHF-tau from Alzheimer's disease brain
    • Mulot SF, Hughes K, Woodgett JR, Anderton BH, Hanger DP. 1995. Phosphorylation of tau by glycogen synthase kinase-3 beta in vitro produces species with similar electrophoretic and immunogenic properties to PHF-tau from Alzheimer's disease brain. Biochem Soc Trans 23:45S.
    • (1995) Biochem Soc Trans , vol.23
    • Mulot, S.F.1    Hughes, K.2    Woodgett, J.R.3    Anderton, B.H.4    Hanger, D.P.5
  • 53
    • 0028981219 scopus 로고
    • Structure-activity analyses of beta-amyloid peptides: Contributions of the beta 25-35 region to aggregation and neurotoxicity
    • Pike CJ, Walencewicz-Wasserman AJ, Kosmoski J, Cribbs DH, Glabe CG, Cotman CW. 1995. Structure-activity analyses of beta-amyloid peptides: contributions of the beta 25-35 region to aggregation and neurotoxicity. J Neurochem 64:253-265.
    • (1995) J Neurochem , vol.64 , pp. 253-265
    • Pike, C.J.1    Walencewicz-Wasserman, A.J.2    Kosmoski, J.3    Cribbs, D.H.4    Glabe, C.G.5    Cotman, C.W.6
  • 54
    • 33644974691 scopus 로고    scopus 로고
    • Effect of erythropoietin on staurosporine-induced apoptosis and differentiation of SH-SY5Y neuroblastoma cells
    • Pregi N, Vittori D, Perez G, Leiros CP, Nesse A. 2006. Effect of erythropoietin on staurosporine-induced apoptosis and differentiation of SH-SY5Y neuroblastoma cells. Biochim Biophys Acta 1763:238-246.
    • (2006) Biochim Biophys Acta , vol.1763 , pp. 238-246
    • Pregi, N.1    Vittori, D.2    Perez, G.3    Leiros, C.P.4    Nesse, A.5
  • 55
    • 0033548048 scopus 로고    scopus 로고
    • Erythropoietin receptor activation by a ligand-induced conformation change
    • Remy I, Wilson IA, Michnick SW. 1999. Erythropoietin receptor activation by a ligand-induced conformation change. Science 283:990-993.
    • (1999) Science , vol.283 , pp. 990-993
    • Remy, I.1    Wilson, I.A.2    Michnick, S.W.3
  • 56
    • 0037155824 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3 couples AKT-dependent signaling to the regulation of p21Cip1 degradation
    • Rossig L, Badorff C, Holzmann Y, Zeiher AM, Dimmeler S. 2002. Glycogen synthase kinase-3 couples AKT-dependent signaling to the regulation of p21Cip1 degradation. J Biol Chem 277:9684-9689.
    • (2002) J Biol Chem , vol.277 , pp. 9684-9689
    • Rossig, L.1    Badorff, C.2    Holzmann, Y.3    Zeiher, A.M.4    Dimmeler, S.5
  • 59
    • 0242656408 scopus 로고    scopus 로고
    • Akt/GSK3beta serine/threonine kinases: Evidence for a signalling pathway mediated by familial Alzheimer's disease mutations
    • Ryder J, Su Y, Ni B. 2004. Akt/GSK3beta serine/threonine kinases: evidence for a signalling pathway mediated by familial Alzheimer's disease mutations. Cell Signalling 16:187-200.
    • (2004) Cell Signalling , vol.16 , pp. 187-200
    • Ryder, J.1    Su, Y.2    Ni, B.3
  • 60
    • 0034680872 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase plays an essential role in the erythropoietin-dependent proliferation of CTLL-2 cells
    • Sakamoto H, Kitamura T, Yoshimura A. 2000. Mitogen-activated protein kinase plays an essential role in the erythropoietin-dependent proliferation of CTLL-2 cells. J Biol Chem 275:35857-35862.
    • (2000) J Biol Chem , vol.275 , pp. 35857-35862
    • Sakamoto, H.1    Kitamura, T.2    Yoshimura, A.3
  • 62
    • 0034284026 scopus 로고    scopus 로고
    • Erythropoietin protects cultured cortical neurons, but not astroglia, from hypoxia and AMPA toxicity
    • Sinor AD, Greenberg DA. 2000. Erythropoietin protects cultured cortical neurons, but not astroglia, from hypoxia and AMPA toxicity. Neurosci Lett 290:213-215.
    • (2000) Neurosci Lett , vol.290 , pp. 213-215
    • Sinor, A.D.1    Greenberg, D.A.2
  • 66
    • 0032529283 scopus 로고    scopus 로고
    • Synergistic activation of MAP kinase (ERK1/2) by erythropoietin and stem cell factor is essential for expanded erythropoiesis
    • Sui X, Krantz SB, You M, Zhao Z. 1998. Synergistic activation of MAP kinase (ERK1/2) by erythropoietin and stem cell factor is essential for expanded erythropoiesis. Blood 92:1142-1149.
    • (1998) Blood , vol.92 , pp. 1142-1149
    • Sui, X.1    Krantz, S.B.2    You, M.3    Zhao, Z.4
  • 67
    • 0033890345 scopus 로고    scopus 로고
    • Stem cell factor and erythropoietin inhibit apoptosis of human erythroid progenitor cells through different signalling pathways
    • Sui X, Krantz SB, Zhao ZJ. 2000. Stem cell factor and erythropoietin inhibit apoptosis of human erythroid progenitor cells through different signalling pathways. Br J Haematol 110:63-70.
    • (2000) Br J Haematol , vol.110 , pp. 63-70
    • Sui, X.1    Krantz, S.B.2    Zhao, Z.J.3
  • 68
    • 30044451865 scopus 로고    scopus 로고
    • Vascular endothelial growth factor-B (VEGFB) stimulates neurogenesis: Evidence from knockout mice and growth factor administration
    • Sun Y, Jin K, Childs JT, Xie L, Mao XO, Greenberg DA. 2006. Vascular endothelial growth factor-B (VEGFB) stimulates neurogenesis: evidence from knockout mice and growth factor administration. Dev Biol 289:329-335.
    • (2006) Dev Biol , vol.289 , pp. 329-335
    • Sun, Y.1    Jin, K.2    Childs, J.T.3    Xie, L.4    Mao, X.O.5    Greenberg, D.A.6
  • 70
    • 0030044463 scopus 로고    scopus 로고
    • Exposure of rat hippocampal neurons to amyloid beta peptide 25-35 induces the inactivation of phosphatidyl inositol-3 kinase and the activation of tau protein kinase I/glycogen synthase kinase-3 beta
    • Takashima A, Noguchi K, Michel G, Mercken M, Hoshi M, Ishiguro K, Imahori K. 1996. Exposure of rat hippocampal neurons to amyloid beta peptide 25-35 induces the inactivation of phosphatidyl inositol-3 kinase and the activation of tau protein kinase I/glycogen synthase kinase-3 beta. Neurosc Lett 203:33-36.
    • (1996) Neurosc Lett , vol.203 , pp. 33-36
    • Takashima, A.1    Noguchi, K.2    Michel, G.3    Mercken, M.4    Hoshi, M.5    Ishiguro, K.6    Imahori, K.7
  • 71
    • 0031695652 scopus 로고    scopus 로고
    • Activation of tau protein kinase I/ glycogen synthase kinase-3beta by amyloid beta peptide 25-35 enhances phosphorylation of tau in hippocampal neurons
    • Takashima A, Honda T, Yasutake K, Michel G, Murayama O, Murayama M, Ishiguro K, Yamaguchi H. 1998. Activation of tau protein kinase I/ glycogen synthase kinase-3beta by amyloid beta peptide 25-35 enhances phosphorylation of tau in hippocampal neurons. Neurosci Res 31:317-323.
    • (1998) Neurosci Res , vol.31 , pp. 317-323
    • Takashima, A.1    Honda, T.2    Yasutake, K.3    Michel, G.4    Murayama, O.5    Murayama, M.6    Ishiguro, K.7    Yamaguchi, H.8
  • 73
    • 11244276997 scopus 로고    scopus 로고
    • VEGF overexpression induces post-ischaemic neuroprotection, but facilitates haemodynamic steal phenomena
    • Wang Y, Kilic E, Kilic U, Weber B, Bassetti CL, Marti HH, Hermann DM. 2005. VEGF overexpression induces post-ischaemic neuroprotection, but facilitates haemodynamic steal phenomena. Brain 128:52-63.
    • (2005) Brain , vol.128 , pp. 52-63
    • Wang, Y.1    Kilic, E.2    Kilic, U.3    Weber, B.4    Bassetti, C.L.5    Marti, H.H.6    Hermann, D.M.7
  • 75
    • 33746456956 scopus 로고    scopus 로고
    • Effects of endogenous beta-amyloid overproduction on tau phosphorylation in cell culture
    • Wang ZF, Li HL, Li XC, Zhang Q, Tian Q, Wang Q, Xu H, Wang JZ. 2006. Effects of endogenous beta-amyloid overproduction on tau phosphorylation in cell culture. J Neurochem 98:1167-1175.
    • (2006) J Neurochem , vol.98 , pp. 1167-1175
    • Wang, Z.F.1    Li, H.L.2    Li, X.C.3    Zhang, Q.4    Tian, Q.5    Wang, Q.6    Xu, H.7    Wang, J.Z.8
  • 77
    • 33845291088 scopus 로고    scopus 로고
    • Mitogen activated protein kinase and protein kinase C activation mediate promotion of sAPPalpha secretion by deprenyl
    • Yang HQ, Ba MW, Ren RJ, Zhang YH, Ma JF, Pan J, Lu GQ, Chen SD. 2007. Mitogen activated protein kinase and protein kinase C activation mediate promotion of sAPPalpha secretion by deprenyl. Neurochem Int 50:74-82.
    • (2007) Neurochem Int , vol.50 , pp. 74-82
    • Yang, H.Q.1    Ba, M.W.2    Ren, R.J.3    Zhang, Y.H.4    Ma, J.F.5    Pan, J.6    Lu, G.Q.7    Chen, S.D.8
  • 78
    • 0024990330 scopus 로고
    • Neurotrophic and neurotoxic effects of amyloid beta protein: Reversal by tachykinin neuropeptides
    • Yankner BA, Duffy LK, Kirschner DA. 1990. Neurotrophic and neurotoxic effects of amyloid beta protein: reversal by tachykinin neuropeptides. Science 250:279-282.
    • (1990) Science , vol.250 , pp. 279-282
    • Yankner, B.A.1    Duffy, L.K.2    Kirschner, D.A.3
  • 79
    • 34250828995 scopus 로고    scopus 로고
    • Erythropoietin promotes survival of primary human endothelial cells through PI3K-dependent, NF-kappaB-independent upregulation of Bcl-xL
    • Zhande R, Karsan A. 2007. Erythropoietin promotes survival of primary human endothelial cells through PI3K-dependent, NF-kappaB-independent upregulation of Bcl-xL. Am J Physiol Heart Circ Physiol 292:H2467-H2474.
    • (2007) Am J Physiol Heart Circ Physiol , vol.292
    • Zhande, R.1    Karsan, A.2
  • 80
    • 0037110601 scopus 로고    scopus 로고
    • Amyloid beta peptide induces tau phosphorylation and loss of cholinergic neurons in rat primary septal cultures
    • Zheng WH, Bastianetto S, Mennicken F, Ma W, Kar S. 2002. Amyloid beta peptide induces tau phosphorylation and loss of cholinergic neurons in rat primary septal cultures. Neuroscience 115:201-211.
    • (2002) Neuroscience , vol.115 , pp. 201-211
    • Zheng, W.H.1    Bastianetto, S.2    Mennicken, F.3    Ma, W.4    Kar, S.5
  • 81
    • 0036770144 scopus 로고    scopus 로고
    • The role of mitogen-activated protein kinase pathways in Alzheimer's disease
    • Zhu X, Lee HG, Raina AK, Perry G, Smith MA. 2002. The role of mitogen-activated protein kinase pathways in Alzheimer's disease. Neurosignals 11:270-281.
    • (2002) Neurosignals , vol.11 , pp. 270-281
    • Zhu, X.1    Lee, H.G.2    Raina, A.K.3    Perry, G.4    Smith, M.A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.