N-Pyridinyl-indole-3-(alkyl)carboxamides and derivatives as potential systemic and topical inflammation inhibitors

European Journal of Medicinal Chemistry

Volumn 36, Issue 6, 2001, Pages 545-553

  Duflos, Muriel ^a   Nourrisson, Marie Renée ^a   Brelet, Jacques ^a   Courant, Jacqueline ^a   LeBaut, Guillaume ^a   Grimaud, Nicole ^a   Petit, Jean Yves ^a  

^a UNIVERSITÉ DE NANTES   (France)

Author keywords

3 Indol(alkyl)carboxamides; Amino(methyl)pyridines (derivatives of); Systemic and topical inflammation inhibitors

Indexed keywords

1 [[5 BROMO 1 (4 FLUOROBENZYL)INDOL 3 YL]CARBONYL] 4 BENZYLPIPERAZINE; AMIDE; ANTIINFLAMMATORY AGENT; CARRAGEENAN; N (4 PYRIDINYL) (5 BROMO 1 METHYLINDOL 3 YL)CARBOXAMIDE; N (4,6 DIMETHYLPYRIDIN 2 YL) (5 BROMO 1 METHYLINDOL 3 YL)CARBOXAMIDE; N (4,6 DIMETHYLPYRIDIN 2 YL) [5 BROMO 1 (4 FLUOROBENZYL)INDOL 3 YL]CARBOXAMIDE; N (PYRIDIN 4 YL) (5 FLUOROINDOL 3 YL)PROPANAMIDE; N (PYRIDIN 4 YL) (INDOL 3 YL)ACETAMIDE; N (PYRIDIN 4 YL) (INDOL 3 YL)PROPANAMIDE; N (PYRIDIN 4 YL) [5 BROMO 1 (4 FLUOROBENZYL)INDOL 3 YL]CARBOXAMIDE; N [(PYRIDIN 3 YL)METHYL] [5 BROMO 1 (4 FLUOROBENZYL)INDOL 3 YL]CARBOXAMIDE; N PYRIDINYLINDOLE 3 CARBOXAMIDE DERIVATIVE; PHORBOL 13 ACETATE 12 MYRISTATE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL SWELLING; CHEMICAL REACTION; CONTROLLED STUDY; DRUG EFFICACY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; EAR; MALE; NONHUMAN; PAW EDEMA; RAT;

ADMINISTRATION, TOPICAL; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CARRAGEENAN; DRUG DESIGN; DRUG EVALUATION, PRECLINICAL; EAR, EXTERNAL; EDEMA; INDOLES; INFLAMMATION; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MICE; PYRIDINES; RATS; SPECTROPHOTOMETRY, INFRARED; STRUCTURE-ACTIVITY RELATIONSHIP; TETRADECANOYLPHORBOL ACETATE;

EID: 0035357540     PISSN: 02235234     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0223-5234(01)01242-9     Document Type: Article

References (31)