Roles of adenine anchoring and ion pairing at the coenzyme B 12-binding site in diol dehydratase catalysis

FEBS Journal

Volumn 275, Issue 24, 2008, Pages 6204-6216

  Ogura, Ken Ichi ^a   Kunita, Shin Ichi ^a   Mori, Koichi ^a   Tobimatsu, Takamasa ^a   Toraya, Tetsuo ^a  

^a OKAYAMA UNIVERSITY   (Japan)

Author keywords

Adenine anchoring; Adenosylcobalamin; Coenzyme B12; Diol dehydratase; Ion pairing

Indexed keywords

5' DEOXYADENOSINE; ADENINE; APOENZYME; CARBON; COBALAMIN; COBALT; COBAMAMIDE; DIOL DEHYDRATASE; HOLOENZYME; HYDROLYASE; LYSINE; OXYGEN; SERINE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BINDING SITE; CATALYSIS; CHEMICAL BOND; ENZYME ACTIVATION; ENZYME BINDING; ENZYME INACTIVATION; MOLECULAR DYNAMICS; MUTANT; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; SURFACE CHARGE; WILD TYPE;

ADENINE; AMINO ACID SUBSTITUTION; BINDING SITES; CATALYSIS; COBAMIDES; HYDROGEN BONDING; KINETICS; LYSINE; MODELS, MOLECULAR; PROPANEDIOL DEHYDRATASE; PROTEIN CONFORMATION; RECOMBINANT PROTEINS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SERINE; SUBSTRATE SPECIFICITY; VITAMIN B 12;

EID: 56849117882     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2008.06745.x     Document Type: Article

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