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Volumn 40, Issue 8, 2008, Pages 584-593

High-density lipoprotein: A fall from grace?

Author keywords

Anacetrapib; Atherosclerosis; Atherothrombosis; CETP inhibition; Endothelium; HDL; Inflammation; LXR; PPAR; Torcetrapib

Indexed keywords

2 METHYLPROPANETHIOIC ACID S [2 [1 (2 ETHYLBUTYL)CYCLOHEXYLCARBOXAMIDO]PHENYL] ESTER; ANACETRAPIB; ANTISENSE OLIGONUCLEOTIDE; APL 180; APOLIPOPROTEIN AI MILANO; ATORVASTATIN; CHOLESTEROL ESTER TRANSFER PROTEIN; CHOLESTEROL ESTER TRANSFER PROTEIN INHIBITOR; HIGH DENSITY LIPOPROTEIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LIVER X RECEPTOR; LIVER X RECEPTOR AGONIST; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; RECOMBINANT APOLIPOPROTEIN AI MILANO PHOSPHOLIPID COMPLEX; RECOMBINANT PROTEIN; TORCETRAPIB; UNCLASSIFIED DRUG;

EID: 56749140708     PISSN: 07853890     EISSN: 16512219     Source Type: Journal    
DOI: 10.1080/07853890802082104     Document Type: Review
Times cited : (9)

References (68)
  • 1
    • 50449152044 scopus 로고    scopus 로고
    • Barr DP, Russ EM, Eder HA. Protein-lipid relationships in human plasma. II. In atherosclerosis and related conditions. Am J Med. 1951;11:480-93.
    • Barr DP, Russ EM, Eder HA. Protein-lipid relationships in human plasma. II. In atherosclerosis and related conditions. Am J Med. 1951;11:480-93.
  • 2
    • 0017384270 scopus 로고
    • High density lipoprotein as a protective factor against coronary heart disease. The Framingham Study
    • Gordon T, Castelli WP, Hjortland MC, Kannel WB, Dawber TR. High density lipoprotein as a protective factor against coronary heart disease. The Framingham Study. Am J Med. 1977;62:707-14.
    • (1977) Am J Med , vol.62 , pp. 707-714
    • Gordon, T.1    Castelli, W.P.2    Hjortland, M.C.3    Kannel, W.B.4    Dawber, T.R.5
  • 3
    • 0020595075 scopus 로고
    • High-density lipoproteins: Epidemiologic profile and risks of coronary artery disease
    • Kannel WB. High-density lipoproteins: epidemiologic profile and risks of coronary artery disease. Am J Cardiol. 1983;52:9B-12B.
    • (1983) Am J Cardiol , vol.52
    • Kannel, W.B.1
  • 4
    • 34748887666 scopus 로고    scopus 로고
    • HDL cholesterol, very low levels of LDL cholesterol, and cardiovascular events
    • Barter P, Gotto AM, LaRosa JC, Maroni J, Szarek M, Grundy SM, et al. HDL cholesterol, very low levels of LDL cholesterol, and cardiovascular events. N Engl J Med. 2007;357:1301-10.
    • (2007) N Engl J Med , vol.357 , pp. 1301-1310
    • Barter, P.1    Gotto, A.M.2    LaRosa, J.C.3    Maroni, J.4    Szarek, M.5    Grundy, S.M.6
  • 5
    • 4644356978 scopus 로고    scopus 로고
    • A novel apoA-I mutation (L178P) leads to endothelial dysfunction, increased arterial wall thickness, and premature coronary artery disease
    • Hovingh GK, Brownlie A, Bisoendial RJ, Dube MP, Levels JH, Petersen W, et al. A novel apoA-I mutation (L178P) leads to endothelial dysfunction, increased arterial wall thickness, and premature coronary artery disease. J Am Coll Cardiol. 2004;44:1429-35.
    • (2004) J Am Coll Cardiol , vol.44 , pp. 1429-1435
    • Hovingh, G.K.1    Brownlie, A.2    Bisoendial, R.J.3    Dube, M.P.4    Levels, J.H.5    Petersen, W.6
  • 6
    • 0034020289 scopus 로고    scopus 로고
    • Paraoxonase gene polymorphisms are associated with carotid arterial wall thickness in subjects with familial hypercholesterolemia
    • Leus FR, Wittekoek ME, Prins J, Kastelein JJ, Voorbij HA. Paraoxonase gene polymorphisms are associated with carotid arterial wall thickness in subjects with familial hypercholesterolemia. Atherosclerosis. 2000;149:371-7.
    • (2000) Atherosclerosis , vol.149 , pp. 371-377
    • Leus, F.R.1    Wittekoek, M.E.2    Prins, J.3    Kastelein, J.J.4    Voorbij, H.A.5
  • 10
    • 0037180771 scopus 로고    scopus 로고
    • Inflammation in atherosclerosis
    • Libby P. Inflammation in atherosclerosis. Nature. 2002;420:868-74.
    • (2002) Nature , vol.420 , pp. 868-874
    • Libby, P.1
  • 11
    • 16344390798 scopus 로고    scopus 로고
    • Reconstituted high-density lipoproteins inhibit the acute pro-oxidant and proinflammatory vascular changes induced by a periarterial collar in normocholesterolemic rabbits
    • Nicholls SJ, Dusting GJ, Cutri B, Bao S, Drummond GR, Rye KA, et al. Reconstituted high-density lipoproteins inhibit the acute pro-oxidant and proinflammatory vascular changes induced by a periarterial collar in normocholesterolemic rabbits. Circulation. 2005;111:1543-50.
    • (2005) Circulation , vol.111 , pp. 1543-1550
    • Nicholls, S.J.1    Dusting, G.J.2    Cutri, B.3    Bao, S.4    Drummond, G.R.5    Rye, K.A.6
  • 12
    • 0035871793 scopus 로고    scopus 로고
    • Apolipoprotein A-I inhibits the production of interleukin-1beta and tumor necrosis factor-alpha by blocking contact-mediated activation of monocytes by T lymphocytes
    • Hyka N, Dayer JM, Modoux C, Kohno T, Edwards CK 3rd, Roux-Lombard P, et al. Apolipoprotein A-I inhibits the production of interleukin-1beta and tumor necrosis factor-alpha by blocking contact-mediated activation of monocytes by T lymphocytes. Blood. 2001;97:2381-9.
    • (2001) Blood , vol.97 , pp. 2381-2389
    • Hyka, N.1    Dayer, J.M.2    Modoux, C.3    Kohno, T.4    Edwards 3rd, C.K.5    Roux-Lombard, P.6
  • 13
  • 14
    • 33644651160 scopus 로고    scopus 로고
    • Liver X receptors as integrators of metabolic and inflammatory signaling
    • Zelcer N, Tontonoz P. Liver X receptors as integrators of metabolic and inflammatory signaling. J Clin Invest. 2006;116:607-14.
    • (2006) J Clin Invest , vol.116 , pp. 607-614
    • Zelcer, N.1    Tontonoz, P.2
  • 18
    • 0025104275 scopus 로고
    • Increased high-density lipoprotein levels caused by a common cholesteryl-ester transfer protein gene mutation
    • Inazu A, Brown ML, Hesler CB, Agellon LB, Koizumi J, Takata K, et al. Increased high-density lipoprotein levels caused by a common cholesteryl-ester transfer protein gene mutation. N Engl J Med. 1990;323:1234-8.
    • (1990) N Engl J Med , vol.323 , pp. 1234-1238
    • Inazu, A.1    Brown, M.L.2    Hesler, C.B.3    Agellon, L.B.4    Koizumi, J.5    Takata, K.6
  • 19
    • 4544230882 scopus 로고    scopus 로고
    • Plasma levels of cholesteryl ester transfer protein and the risk of future coronary artery disease in apparently healthy men and women: The prospective EPIC (European Prospective Investigation into Cancer and nutrition)-Norfolk population study
    • Boekholdt SM, Kuivenhoven JA, Wareham NJ, Peters RJ, Jukema JW, Luben R, et al. Plasma levels of cholesteryl ester transfer protein and the risk of future coronary artery disease in apparently healthy men and women: the prospective EPIC (European Prospective Investigation into Cancer and nutrition)-Norfolk population study. Circulation. 2004;110:1418-23.
    • (2004) Circulation , vol.110 , pp. 1418-1423
    • Boekholdt, S.M.1    Kuivenhoven, J.A.2    Wareham, N.J.3    Peters, R.J.4    Jukema, J.W.5    Luben, R.6
  • 20
    • 0032917975 scopus 로고    scopus 로고
    • Increased atherosclerosis in ApoE and LDL receptor gene knock-out mice as a result of human cholesteryl ester transfer protein transgene expression
    • Plump AS, Masucci-Magoulas L, Bruce C, Bisgaier CL, Breslow JL, Tall AR. Increased atherosclerosis in ApoE and LDL receptor gene knock-out mice as a result of human cholesteryl ester transfer protein transgene expression. Arterioscler Thromb Vasc Biol. 1999;19:1105-10.
    • (1999) Arterioscler Thromb Vasc Biol , vol.19 , pp. 1105-1110
    • Plump, A.S.1    Masucci-Magoulas, L.2    Bruce, C.3    Bisgaier, C.L.4    Breslow, J.L.5    Tall, A.R.6
  • 22
    • 0032735679 scopus 로고    scopus 로고
    • Spontaneous combined hyperlipidemia, coronary heart disease and decreased survival in Dahl salt-sensitive hypertensive rats transgenic for human cholesteryl ester transfer protein
    • Herrera VL, Makrides SC, Xie HX, Adari H, Krauss RM, Ryan US, et al. Spontaneous combined hyperlipidemia, coronary heart disease and decreased survival in Dahl salt-sensitive hypertensive rats transgenic for human cholesteryl ester transfer protein. Nat Med. 1999;5:1383-9.
    • (1999) Nat Med , vol.5 , pp. 1383-1389
    • Herrera, V.L.1    Makrides, S.C.2    Xie, H.X.3    Adari, H.4    Krauss, R.M.5    Ryan, U.S.6
  • 23
    • 0028784246 scopus 로고
    • Decreased early atherosclerotic lesions in hypertriglyceridemic mice expressing cholesteryl ester transfer protein transgene
    • Hayek T, Masucci-Magoulas L, Jiang X, Walsh A, Rubin E, Breslow JL, et al. Decreased early atherosclerotic lesions in hypertriglyceridemic mice expressing cholesteryl ester transfer protein transgene. J Clin Invest. 1995;96:2071-4.
    • (1995) J Clin Invest , vol.96 , pp. 2071-2074
    • Hayek, T.1    Masucci-Magoulas, L.2    Jiang, X.3    Walsh, A.4    Rubin, E.5    Breslow, J.L.6
  • 24
    • 0034644214 scopus 로고    scopus 로고
    • A cholesteryl ester transfer protein inhibitor attenuates atherosclerosis in rabbits
    • Okamoto H, Yonemori F, Wakitani K, Minowa T, Maeda K, Shinkai H. A cholesteryl ester transfer protein inhibitor attenuates atherosclerosis in rabbits. Nature. 2000;406:203-7.
    • (2000) Nature , vol.406 , pp. 203-207
    • Okamoto, H.1    Yonemori, F.2    Wakitani, K.3    Minowa, T.4    Maeda, K.5    Shinkai, H.6
  • 26
    • 0032570684 scopus 로고    scopus 로고
    • Effect of antisense oligonucleotides against cholesteryl ester transfer protein on the development of atherosclerosis in cholesterol-fed rabbits
    • Sugano MN, Makino S, Sawada S, Otsuka M, Watanabe H, Okamoto M, et al. Effect of antisense oligonucleotides against cholesteryl ester transfer protein on the development of atherosclerosis in cholesterol-fed rabbits. J Biol Chem. 1998;273:5033-6.
    • (1998) J Biol Chem , vol.273 , pp. 5033-5036
    • Sugano, M.N.1    Makino, S.2    Sawada, S.3    Otsuka, M.4    Watanabe, H.5    Okamoto, M.6
  • 27
    • 0037035459 scopus 로고    scopus 로고
    • Efficacy and safety of a novel cholesteryl ester transfer protein inhibitor, JTT-705, in humans: A randomized phase II dose-response study
    • de Grooth GJ, Kuivenhoven JA, Stalenhoef AF, de Graaf J, Zwinderman AH, Posma JL, et al. Efficacy and safety of a novel cholesteryl ester transfer protein inhibitor, JTT-705, in humans: a randomized phase II dose-response study. Circulation. 2002;105:2159-65.
    • (2002) Circulation , vol.105 , pp. 2159-2165
    • de Grooth, G.J.1    Kuivenhoven, J.A.2    Stalenhoef, A.F.3    de Graaf, J.4    Zwinderman, A.H.5    Posma, J.L.6
  • 30
    • 34247351950 scopus 로고    scopus 로고
    • Designs of RADIANCE 1 and 2: Carotid ultrasound studies comparing the effects of torcetrapib/atorvastatin with atorvastatin alone on atherosclerosis
    • Kastelein JJ, van Leuven SI, Evans GW, Riley WA, Revkin JH, Shear CL, et al. Designs of RADIANCE 1 and 2: carotid ultrasound studies comparing the effects of torcetrapib/atorvastatin with atorvastatin alone on atherosclerosis. Curr Med Res Opin. 2007;23:885-94.
    • (2007) Curr Med Res Opin , vol.23 , pp. 885-894
    • Kastelein, J.J.1    van Leuven, S.I.2    Evans, G.W.3    Riley, W.A.4    Revkin, J.H.5    Shear, C.L.6
  • 32
    • 34447265547 scopus 로고    scopus 로고
    • Torcetrapib and carotid intima-media thickness in mixed dyslipidaemia (RADIANCE 2 study): A randomised, double-blind trial
    • Bots ML, Visseren FL, Evans GW, Riley WA, Revkin JH, Tegeler CH, et al. Torcetrapib and carotid intima-media thickness in mixed dyslipidaemia (RADIANCE 2 study): a randomised, double-blind trial. Lancet. 2007;370:153-60.
    • (2007) Lancet , vol.370 , pp. 153-160
    • Bots, M.L.1    Visseren, F.L.2    Evans, G.W.3    Riley, W.A.4    Revkin, J.H.5    Tegeler, C.H.6
  • 34
    • 33846424247 scopus 로고    scopus 로고
    • The failure of torcetrapib: Was it the molecule or the mechanism?
    • Tall AR, Yvan-Charvet L, Wang N. The failure of torcetrapib: was it the molecule or the mechanism? Arterioscler Thromb Vasc Biol. 2007;27:257-60.
    • (2007) Arterioscler Thromb Vasc Biol , vol.27 , pp. 257-260
    • Tall, A.R.1    Yvan-Charvet, L.2    Wang, N.3
  • 35
    • 36549078679 scopus 로고    scopus 로고
    • Effect of the cholesteryl ester transfer protein inhibitor, anacetrapib, on lipoproteins in patients with dyslipidaemia and on 24-h ambulatory blood pressure in healthy individuals: Two double-blind, randomised placebo-controlled phase I studies
    • Krishna R, Anderson MS, Bergman AJ, Jin B, Fallon M, Cote J, et al. Effect of the cholesteryl ester transfer protein inhibitor, anacetrapib, on lipoproteins in patients with dyslipidaemia and on 24-h ambulatory blood pressure in healthy individuals: two double-blind, randomised placebo-controlled phase I studies. Lancet. 2007;370:1907-14.
    • (2007) Lancet , vol.370 , pp. 1907-1914
    • Krishna, R.1    Anderson, M.S.2    Bergman, A.J.3    Jin, B.4    Fallon, M.5    Cote, J.6
  • 36
    • 54249168193 scopus 로고    scopus 로고
    • Torcetrapib-induced blood pressure elevation is independent of cholesteryl ester transfer protein inhibition and is accompanied by an increase in circulating aldosterone levels
    • Forrest MJ, Briscoe RJ, Ehrhart J, Hershey JC, Ma X, Peterson LB, et al. Torcetrapib-induced blood pressure elevation is independent of cholesteryl ester transfer protein inhibition and is accompanied by an increase in circulating aldosterone levels. Circ Res. 2007;101:1209.
    • (2007) Circ Res , vol.101 , pp. 1209
    • Forrest, M.J.1    Briscoe, R.J.2    Ehrhart, J.3    Hershey, J.C.4    Ma, X.5    Peterson, L.B.6
  • 37
    • 56849100669 scopus 로고    scopus 로고
    • Kastelein JJ. Presented at the conference of the American Heart Association. Proceeding of satalite symposia, Orlando, 3-7 November 2007.
    • Kastelein JJ. Presented at the conference of the American Heart Association. Proceeding of satalite symposia, Orlando, 3-7 November 2007.
  • 38
    • 56849131012 scopus 로고    scopus 로고
    • Nissen SE. Presented at the conference of the American Heart Association. Proceeding of satalite symposia, Orlando, 3-7 November 2007.
    • Nissen SE. Presented at the conference of the American Heart Association. Proceeding of satalite symposia, Orlando, 3-7 November 2007.
  • 39
    • 36349016109 scopus 로고    scopus 로고
    • Illuminating HDL - is it still a viable therapeutic target?
    • Rader DJ. Illuminating HDL - is it still a viable therapeutic target? N Engl J Med. 2007;357:2180-3.
    • (2007) N Engl J Med , vol.357 , pp. 2180-2183
    • Rader, D.J.1
  • 40
    • 0029801069 scopus 로고    scopus 로고
    • Production and characterization of a reconstituted high density lipoprotein for therapeutic applications
    • Lerch PG, Fortsch V, Hodler G, Bolli R. Production and characterization of a reconstituted high density lipoprotein for therapeutic applications. Vox Sang. 1996;71:155-64.
    • (1996) Vox Sang , vol.71 , pp. 155-164
    • Lerch, P.G.1    Fortsch, V.2    Hodler, G.3    Bolli, R.4
  • 42
    • 27644535714 scopus 로고    scopus 로고
    • Impact of short-term administration of high-density lipoproteins and atorvastatin on atherosclerosis in rabbits
    • Nicholls SJ, Cutri B, Worthley SG, Kee P, Rye KA, Bao S, et al. Impact of short-term administration of high-density lipoproteins and atorvastatin on atherosclerosis in rabbits. Arterioscler Thromb Vasc Biol. 2005;25:2416-21.
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 2416-2421
    • Nicholls, S.J.1    Cutri, B.2    Worthley, S.G.3    Kee, P.4    Rye, K.A.5    Bao, S.6
  • 43
    • 0038311032 scopus 로고    scopus 로고
    • Restoration of endothelial function by increasing high-density lipoprotein in subjects with isolated low high-density lipoprotein
    • Bisoendial RJ, Hovingh GK, Levels JH, Lerch PG, Andresen I, Hayden MR, et al. Restoration of endothelial function by increasing high-density lipoprotein in subjects with isolated low high-density lipoprotein. Circulation. 2003;107:2944-8.
    • (2003) Circulation , vol.107 , pp. 2944-2948
    • Bisoendial, R.J.1    Hovingh, G.K.2    Levels, J.H.3    Lerch, P.G.4    Andresen, I.5    Hayden, M.R.6
  • 44
    • 0037177140 scopus 로고    scopus 로고
    • High-density lipoprotein restores endothelial function in hypercholesterolemic men
    • Spieker LE, Sudano I, Hurlimann D, Lerch PG, Lang MG, Binggeli C, et al. High-density lipoprotein restores endothelial function in hypercholesterolemic men. Circulation. 2002;105:1399-402.
    • (2002) Circulation , vol.105 , pp. 1399-1402
    • Spieker, L.E.1    Sudano, I.2    Hurlimann, D.3    Lerch, P.G.4    Lang, M.G.5    Binggeli, C.6
  • 45
    • 34247397359 scopus 로고    scopus 로고
    • Effects of reconstituted high-density lipoprotein infusions on coronary atherosclerosis: A randomized controlled trial
    • Tardif JC, Gregoire J, L'Allier PL, Ibrahim R, Lespérance J, Heinonen TM, et al. Effects of reconstituted high-density lipoprotein infusions on coronary atherosclerosis: a randomized controlled trial. JAMA. 2007;297:1675-82.
    • (2007) JAMA , vol.297 , pp. 1675-1682
    • Tardif, J.C.1    Gregoire, J.2    L'Allier, P.L.3    Ibrahim, R.4    Lespérance, J.5    Heinonen, T.M.6
  • 46
    • 24944436388 scopus 로고    scopus 로고
    • Cysteine mutants of human apolipoprotein A-I: A study of secondary structural and functional properties
    • Zhu X, Wu G, Zeng W, Xue H, Chen B. Cysteine mutants of human apolipoprotein A-I: a study of secondary structural and functional properties. J Lipid Res. 2005;46:1303-11.
    • (2005) J Lipid Res , vol.46 , pp. 1303-1311
    • Zhu, X.1    Wu, G.2    Zeng, W.3    Xue, H.4    Chen, B.5
  • 47
    • 0019226420 scopus 로고    scopus 로고
    • Franceschini G, Sirtori CR, Capurso A, Weisgraber KH, Mahley RW. A-I Milano apoprotein: decreased high density lipoprotein cholesterol levels with significant lipoprotein modifications and without clinical atherosclerosis in an Italian family. J Clin Invest. 1980;66:892-900.
    • Franceschini G, Sirtori CR, Capurso A, Weisgraber KH, Mahley RW. A-I Milano apoprotein: decreased high density lipoprotein cholesterol levels with significant lipoprotein modifications and without clinical atherosclerosis in an Italian family. J Clin Invest. 1980;66:892-900.
  • 48
    • 29444447092 scopus 로고    scopus 로고
    • ApoA-I Milano/phospholipid complexes emerging pharmacological strategies and medications for the prevention of atherosclerotic plaque progression
    • Kaul S, Shah PK. ApoA-I Milano/phospholipid complexes emerging pharmacological strategies and medications for the prevention of atherosclerotic plaque progression. Curr Drug Targets Cardiovasc Haematol Disord. 2005;5:471-9.
    • (2005) Curr Drug Targets Cardiovasc Haematol Disord , vol.5 , pp. 471-479
    • Kaul, S.1    Shah, P.K.2
  • 49
    • 0032478183 scopus 로고    scopus 로고
    • Effects of recombinant apolipoprotein A-I(Milano) on aortic atherosclerosis in apolipoprotein E-deficient mice
    • Shah PK, Nilsson J, Kaul S, Fishbein MC, Ageland H, Hamsten A, et al. Effects of recombinant apolipoprotein A-I(Milano) on aortic atherosclerosis in apolipoprotein E-deficient mice. Circulation. 1998;97:780-5.
    • (1998) Circulation , vol.97 , pp. 780-785
    • Shah, P.K.1    Nilsson, J.2    Kaul, S.3    Fishbein, M.C.4    Ageland, H.5    Hamsten, A.6
  • 50
    • 35848948176 scopus 로고    scopus 로고
    • Normal vascular function despite low levels of high-density lipoprotein cholesterol in carriers of the apolipoprotein A-I(Milano) mutant
    • Gomaraschi M, Baldassarre D, Amato M, Eligini S, Conca P, Sirtori CR, et al. Normal vascular function despite low levels of high-density lipoprotein cholesterol in carriers of the apolipoprotein A-I(Milano) mutant. Circulation. 2007;116:2165-72.
    • (2007) Circulation , vol.116 , pp. 2165-2172
    • Gomaraschi, M.1    Baldassarre, D.2    Amato, M.3    Eligini, S.4    Conca, P.5    Sirtori, C.R.6
  • 51
    • 0035901577 scopus 로고    scopus 로고
    • Cardiovascular status of carriers of the apolipoprotein A-IMilano mutant: The Limone sul Garda Study
    • Sirtori CR, Calabresi L, Franceschini G, Baldassarre D, Amato M, Johansson J, et al. Cardiovascular status of carriers of the apolipoprotein A-IMilano mutant: the Limone sul Garda Study. Circulation. 2001;103:1949-54.
    • (2001) Circulation , vol.103 , pp. 1949-1954
    • Sirtori, C.R.1    Calabresi, L.2    Franceschini, G.3    Baldassarre, D.4    Amato, M.5    Johansson, J.6
  • 52
    • 0242577955 scopus 로고    scopus 로고
    • Effect of recombinant ApoA-I Milano on coronary atherosclerosis in patients with acute coronary syndromes: A randomized controlled trial
    • Nissen SE, Tsunoda T, Tuzcu EM, Schoenhagen P, Cooper CJ, Yasin M, et al. Effect of recombinant ApoA-I Milano on coronary atherosclerosis in patients with acute coronary syndromes: a randomized controlled trial. JAMA. 2003;290:2292-300.
    • (2003) JAMA , vol.290 , pp. 2292-2300
    • Nissen, S.E.1    Tsunoda, T.2    Tuzcu, E.M.3    Schoenhagen, P.4    Cooper, C.J.5    Yasin, M.6
  • 53
    • 33749118930 scopus 로고    scopus 로고
    • Bone marrow transplantation shows superior atheroprotective effects of gene therapy with apolipoprotein A-I Milano compared with wild-type apolipoprotein A-I in hyperlipidemic mice
    • Wang L, Sharifi BG, Pan T, Song L, Yukht A, Shah PK. Bone marrow transplantation shows superior atheroprotective effects of gene therapy with apolipoprotein A-I Milano compared with wild-type apolipoprotein A-I in hyperlipidemic mice. J Am Coll Cardiol. 2006;48:1459-68.
    • (2006) J Am Coll Cardiol , vol.48 , pp. 1459-1468
    • Wang, L.1    Sharifi, B.G.2    Pan, T.3    Song, L.4    Yukht, A.5    Shah, P.K.6
  • 54
    • 34249082855 scopus 로고    scopus 로고
    • Gene transfer of wild-type apoA-I and apoA-I Milano reduce atherosclerosis to a similar extent
    • Lebherz C, Sanmiguel J, Wilson JM, Rader DJ. Gene transfer of wild-type apoA-I and apoA-I Milano reduce atherosclerosis to a similar extent. Cardiovasc Diabetol. 2007;6:15.
    • (2007) Cardiovasc Diabetol , vol.6 , pp. 15
    • Lebherz, C.1    Sanmiguel, J.2    Wilson, J.M.3    Rader, D.J.4
  • 55
    • 27644454206 scopus 로고    scopus 로고
    • Apolipoprotein A-I and the molecular variant apoA-I(Milano): Evaluation of the antiatherogenic effects in knock-in mouse model
    • Parolini C, Chiesa G, Gong E, Caligari S, Cortese MM, Koga T, et al. Apolipoprotein A-I and the molecular variant apoA-I(Milano): evaluation of the antiatherogenic effects in knock-in mouse model. Atherosclerosis. 2005;183:222-9.
    • (2005) Atherosclerosis , vol.183 , pp. 222-229
    • Parolini, C.1    Chiesa, G.2    Gong, E.3    Caligari, S.4    Cortese, M.M.5    Koga, T.6
  • 56
    • 0022353001 scopus 로고
    • Studies of synthetic peptide analogs of amphipathic helix: Structure of complexes with dimyristoyl phosphatidylcholine
    • Anantharamaiah GM, Jones JL, Brouillette CG, Schmidt CF, Chung BH, Hughes TA, et al. Studies of synthetic peptide analogs of amphipathic helix: structure of complexes with dimyristoyl phosphatidylcholine. J Biol Chem. 1985;260:10248-55.
    • (1985) J Biol Chem , vol.260 , pp. 10248-10255
    • Anantharamaiah, G.M.1    Jones, J.L.2    Brouillette, C.G.3    Schmidt, C.F.4    Chung, B.H.5    Hughes, T.A.6
  • 58
    • 0037154287 scopus 로고    scopus 로고
    • Oral administration of an Apo A-I mimetic peptide synthesized from D-amino acids dramatically reduces atherosclerosis in mice independent of plasma cholesterol
    • Navab M, Anantharamaiah GM, Hama S, Garber DW, Chaddha M, Hough G, et al. Oral administration of an Apo A-I mimetic peptide synthesized from D-amino acids dramatically reduces atherosclerosis in mice independent of plasma cholesterol. Circulation. 2002;105:290-2.
    • (2002) Circulation , vol.105 , pp. 290-292
    • Navab, M.1    Anantharamaiah, G.M.2    Hama, S.3    Garber, D.W.4    Chaddha, M.5    Hough, G.6
  • 59
    • 56849091810 scopus 로고    scopus 로고
    • The ability of apolipoprotein A-I mimetic peptides to improve HDL anti-inflammatory properties is due to their remarkable binding affinities for oxidized lipids
    • van Lenten BJ, Wagner AC, Jung CL, Lehrer RI, Navab M, Fogelman AM. The ability of apolipoprotein A-I mimetic peptides to improve HDL anti-inflammatory properties is due to their remarkable binding affinities for oxidized lipids. Circulation. 2007;116:II-105.
    • (2007) Circulation , vol.116 , Issue.II-105
    • van Lenten, B.J.1    Wagner, A.C.2    Jung, C.L.3    Lehrer, R.I.4    Navab, M.5    Fogelman, A.M.6
  • 60
    • 34249106358 scopus 로고    scopus 로고
    • Oral Administration of the Apolipoprotein A-I Mimetic Peptide D-4F in Humans with CHD Improves HDL Anti-Inflammatory Function After a Single Dose
    • Bloedon LT, Dunbar RL, Duffy D, Pinell-Salles P, Navab M, Fogelman A, et al. Oral Administration of the Apolipoprotein A-I Mimetic Peptide D-4F in Humans with CHD Improves HDL Anti-Inflammatory Function After a Single Dose. Circulation. 2006:114:288.
    • (2006) Circulation , vol.114 , pp. 288
    • Bloedon, L.T.1    Dunbar, R.L.2    Duffy, D.3    Pinell-Salles, P.4    Navab, M.5    Fogelman, A.6
  • 61
    • 0141885327 scopus 로고    scopus 로고
    • Small, dense HDL particles exert potent protection of atherogenic LDL against oxidative stress
    • Kontush A, Chantepie S, Chapman MJ. Small, dense HDL particles exert potent protection of atherogenic LDL against oxidative stress. Arterioscler Thromb Vasc Biol. 2003;23:1881-8.
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 1881-1888
    • Kontush, A.1    Chantepie, S.2    Chapman, M.J.3
  • 62
    • 38749102779 scopus 로고    scopus 로고
    • High-density lipoprotein cholesterol, high-density lipoprotein particle size, and apolipoprotein A-I: Significance for cardiovascular risk: the IDEAL and EPIC-Norfolk studies
    • van der Steeg WA, Holme I, Boekholdt SM, Larsen ML, Lindahl C, Stroes ES, et al. High-density lipoprotein cholesterol, high-density lipoprotein particle size, and apolipoprotein A-I: significance for cardiovascular risk: the IDEAL and EPIC-Norfolk studies. J Am Coll Cardiol. 2008;51:634-42.
    • (2008) J Am Coll Cardiol , vol.51 , pp. 634-642
    • van der Steeg, W.A.1    Holme, I.2    Boekholdt, S.M.3    Larsen, M.L.4    Lindahl, C.5    Stroes, E.S.6
  • 66
    • 33746977703 scopus 로고    scopus 로고
    • Proinflammatory high-density lipoprotein as a biomarker for atherosclerosis in patients with systemic lupus erythematosus and rheumatoid arthritis
    • McMahon M, Grossman J, FitzGerald J, Dahlin-Lee E, Wallace DJ, Thong BY, et al. Proinflammatory high-density lipoprotein as a biomarker for atherosclerosis in patients with systemic lupus erythematosus and rheumatoid arthritis. Arthritis Rheum. 2006;54:2541-9.
    • (2006) Arthritis Rheum , vol.54 , pp. 2541-2549
    • McMahon, M.1    Grossman, J.2    FitzGerald, J.3    Dahlin-Lee, E.4    Wallace, D.J.5    Thong, B.Y.6
  • 68
    • 33847368173 scopus 로고    scopus 로고
    • Shotgun proteomics implicates protease inhibition and complement activation in the antiinflammatory properties of HDL
    • Vaisar T, Pennathur S, Green PS, Gharib SA, Hoofnagle AN, Cheung MC, et al. Shotgun proteomics implicates protease inhibition and complement activation in the antiinflammatory properties of HDL. J Clin Invest. 2007;117:746-56.
    • (2007) J Clin Invest , vol.117 , pp. 746-756
    • Vaisar, T.1    Pennathur, S.2    Green, P.S.3    Gharib, S.A.4    Hoofnagle, A.N.5    Cheung, M.C.6


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