Conserved main-chain peptide distortions: A proposed role for Ile203 in catalysis by dihydrodipicolinate synthase

Protein Science

Volumn 17, Issue 12, 2008, Pages 2080-2090

  Dobson, Renwick C J ^a,b   Griffin, Michael D W ^a,b   Devenish, Sean R A ^c   Pearce, F Grant ^c   Hutton, Craig A ^a,b   Gerrard, Juliet A ^c   Jameson, Geoffrey B ^d   Perugini, Matthew A ^a,b  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c UNIVERSITY OF CANTERBURY   (New Zealand)

^d MASSEY UNIVERSITY   (New Zealand)

Author keywords

Conserved peptide distortion; Dihydrodipicolinate synthase; Lysine biosynthesis; X ray crystallography

Indexed keywords

BETA HYDROXYPYRUVATE; CARBONYL DERIVATIVE; DIAMINOPIMELIC ACID; DIHYDRODIPICOLINATE SYNTHASE; HYDROXYL GROUP; ISOLEUCINE; LYSINE; PYRUVIC ACID; SYNTHETASE; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME STRUCTURE; ENZYME SUBSTRATE; ESCHERICHIA COLI; HYDROGEN BOND; MASS SPECTROMETRY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SEGREGATION DISTORTION;

BIOCATALYSIS; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; ESCHERICHIA COLI; HYDRO-LYASES; ISOLEUCINE; KINETICS; LYSINE; MODELS, MOLECULAR; PEPTIDES; PROTEIN CONFORMATION; PYRUVATES; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; STRUCTURE-ACTIVITY RELATIONSHIP; THERMOTOGA MARITIMA;

ESCHERICHIA COLI;

EID: 56749132990     PISSN: 09618368     EISSN: 1469896X     Source Type: Journal    
DOI: 10.1110/ps.037440.108     Document Type: Article

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