Synergistic effect of Kalpaamruthaa on antiarthritic and antiinflammatory properties - Its mechanism of action

Inflammation

Volumn 31, Issue 6, 2008, Pages 391-398

  Mythilypriya, Rajendran ^a   Shanthi, Palanivelu ^a   Sachdanandam, Panchanadam ^a  

^a UNIVERSITY OF MADRAS   (India)

Author keywords

Adjuvant induced arthritis; Emblica officinalis; Inflammation; Rheumatoid arthritis; Semecarpus anacardium nut

Indexed keywords

ANTIINFLAMMATORY AGENT; ANTIRHEUMATIC AGENT; ASCORBIC ACID; BRADYKININ; CYCLOOXYGENASE 2; DICLOFENAC; EMBLICA OFFICINALIS EXTRACT; FLAVANOID; FLAVONOID; HISTAMINE; KALPAAMRUTHAA; LEUKOTRIENE; NATURAL PRODUCT; OLIVE OIL; PROSTAGLANDIN; SEMECARPUS ANACARDIUM EXTRACT; SEROTONIN; TANNIN; UNCLASSIFIED DRUG;

ADJUVANT ARTHRITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; AYURVEDA; CHRONIC INFLAMMATION; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; DRUG FORMULATION; DRUG MECHANISM; DRUG POTENCY; DRUG POTENTIATION; EMBLICA OFFICINALIS; HONEY; MALE; NONHUMAN; PAW EDEMA; RAT; SEMECARPUS;

ANIMALS; ANTI-INFLAMMATORY AGENTS; ARTHRITIS, EXPERIMENTAL; CARRAGEENAN; COTTON FIBER; DICLOFENAC; DISEASE MODELS, ANIMAL; EDEMA; FREUND'S ADJUVANT; INFLAMMATION; MALE; MEDICINE, AYURVEDIC; NUTS; PLANT EXTRACTS; RATS; RATS, WISTAR; SEMECARPUS; TIME FACTORS;

PHYLLANTHUS EMBLICA; SEMECARPUS ANACARDIUM;

EID: 56649089683     PISSN: 03603997     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10753-008-9090-2     Document Type: Article

References (49)

1. D. A. Corley K. Kerlikowske R. Verma P. Buffler 2003 Protective association of aspirin/NSAIDs and esophageal cancer: a systematic review and meta-analysis Gastroenterology 124 47 56 doi:10.1053/gast.2003.50008
2. Khare, C. P. 2004. Encyclopedia of Indian medicinal plants. Springer, Berlin.
3. G. V. Sathyavathi D. N. Prasad P. K. Das H. D. Singh 1969 Antiinflammatory activity of Semecarpus anacardium Linn. A preliminary study Indian J. Physiol. Pharmacol. 13 37 43
4. V. R. Ramprasath P. Shanthi P. Sachdanandam 2004 Antiinflammatory effect of Semecarpus anacardium Linn. nut extract in acute and chronic inflammatory conditions Biol. Pharm. Bull. 27 2028 2031 doi:10.1248/bpb.27.2028
5. V. R. Ramprasath P. Shanthi P. Sachdanandam 2006 Immunomodulatory and antiinflammatory effects of Semecarpus anacardium Linn. nut milk extract in experimental inflammatory conditions Biol. Pharm. Bull. 29 693 700 doi:10.1248/bpb.29.693
6. K. Sairam C. V. Rao M. D. Babu K. V. Kumar V. K. Agrawal R. K. Goel 2002 Antiulcerogenic effect of methanolic extract of Emblica officinalis: an experimental study J. Ethnopharmacol. 82 1 9 doi:10.1016/S0378-8741(02)00041-7
7. L. Ganju D. Karan S. Chanda K. K. Srivastava R. C. Sawhney W. Selvamurthy 2003 Immunomodulatory effects of agents of plant origin Biomed. Pharmacother. 57 296 300 doi:10.1016/S0753-3322(03)00095-7
8. R. Mythilypriya P. Shanthi P. Sachdanandam 2007 Analgesic, antipyretic and ulcerogenic properties of an indigenous formulation-Kalpaamruthaa Phytother. Res. 21 574 578 doi:10.1002/ptr.2116
9. S. Arulkumaran V. R. Ramprasath P. Shanthi P. Sachdanandam 2006 Restorative effect of kalpaamruthaa, an indigenous preparation, on oxidative damage in mammary gland mitochondrial fraction in experimental mammary carcinoma Mol. Cell. Biochem. 291 77 82 doi:10.1007/s11010-006-9199-2
10. B. Premalatha 2000 Semecarpus anacardium Linn. nuts-a boon in alternative medicine Indian J. Exp. Biol. 38 1177 1182
11. C. Y. Jan U. Takahama M. Kimura 1991 Inhibition of photooxidation of alpha-tocopherol by quercetin in human blood cell membranes in the presence of hematoporphyrin as a photosensitizer Biochim. Biophys. Acta 1086 7 14
12. C. Kandaswami E. Perkins D. S. Soloniuk G. Drzewiecki Jr. E. Middleton 1993 Ascorbic acid-enhanced antiproliferative effect of flavonoids on squamous cell carcinoma in vitro Anticancer Drugs 4 91 96
13. S. T. Senthilmohan J. Zhang R. A. Stanley 2003 Effects of flavonoid extract Enzogenor® with vitamin C on protein oxidation and DNA damage in older human subjects Nutr. Res. 23 1199 1210 doi:10.1016/S0271-5317(03)00127-1
14. S. Ghosal V. K. Tripathy S. Chouhan 1996 Active constituents of Emblica officinalis: Part I-The chemistry and anti-oxidant effect of two new hydrolysable tannins, emblicanin A & B Indian J. Chem. B 35 941 948
15. A. Cherchi L. Spanedda C. Tuberoso P. Cabras 1994 Solid-phase extraction and high-performance liquid-chromatographic determination of organic-acids in honey J. Chromatogr. A 669 59 64 doi:10.1016/0021-9673(94)80336-6
16. Formulary of Siddha Medicine. 1972. Published by the Indian Medical Practitioners Co-operative Pharmacy and Stores Ltd. 2nd ed. Madras, India.
17. T. Vijayalakshmi V. Muthulakshmi P. Sachdanandam 1996 Effect of milk extract of Semecarpus anacardium nut on adjuvant arthritis-a dose dependent study in Wistar albino rats Gen. Pharmacol. 27 1223 1226 doi:10.1016/S0306- 3623(96)00042-0
18. R. Mythilypriya P. Shanthi P. Sachdanandam 2007 Oral acute and subacute toxicity studies with Kalpaamruthaa, a modified indigenous preparation, on rats J. Health Sci. 53 351 358 doi:10.1248/jhs.53.351
19. M. M. Campos J. B. Calixto 1995 Involvement of B1 and B2 receptors in bradykinin-induced rat paw oedema Br. J. Pharmacol. 114 1005 1013
20. C. A. Winter E. A. Risley G. W. Nuss 1962 Carrageenin-induced edema in hind paw of the rat as an assay for antiiflammatory drugs Proc. Soc. Exp. Biol. Med. 111 544 547
21. R. Meier W. Schuler P. Desaulles 1950 On the mechanism of cortisone inhibition of connective tissue proliferation Experimentia 6 469 471 doi:10.1007/BF02154110
22. B. B. Newbould 1963 Chemotherapy of arthritis induced in rats by mycobacterial adjuvant Br. J. Pharmacol. Chemother. 21 127 136
23. B. B. Newbould 1969 The pharmacology of fenclozic acid (2-(4-chlorophenyl)-thiazol-4-ylacetic acid; I.C.I. 54,450; 'Myalex'); a new compound with antiinflammatory, analgesic and antipyretic activity Br. J. Pharmacol. 35 487 497
24. E. J. Lewis J. Bishop S. J. Aspinall 1998 A simple inflammation model that distinguishes between the actions of anti-inflammatory and anti-rheumatic drugs Inflamm. Res. 47 26 35 doi:10.1007/s000110050250
25. S. Silbernagl F. Lang 2000 Atlas de Poche de Physiopathologie. Medicine-Sciences. 1st ed Flammation 2021 320 321
26. A. Ialenti A. Ianaro S. Moncada M. Di Rosa 1992 Modulation of acute inflammation by endogenous nitric oxide Eur. J. Pharmacol. 211 177 182 doi:10.1016/0014-2999(92)90526-A
27. S. K. Kulkarni A. K. Mehta J. Kunchandy 1986 Anti-inflammatory actions of clonidine, guanfacine and B-HT 920 against various inflammagen-induced acute paw oedema in rats Arch. Int. Pharmacodyn. Ther. 279 324 334
28. M. Muniappan T. Sundararaj 2003 Antiinflammatory and antiulcer activities of Bambusa arundinacea J. Ethnopharmacol. 88 161 167 doi:10.1016/S0378-8741(03) 00183-1
29. A. Ueno H. Naraba Y. Ikeda F. Ushikubi T. Murata S. Naramiya 2000 Intrinsic prostacyclin contributes to exudation induced by bradykinin or carrageenin: a study on the paw edema-induced in IP-receptor-deficient mice Life Sci. 66 PL155 160 doi:10.1016/S0024-3205(00)00420-3
30. C. Selvam S. M. Jachak 2004 A cyclooxygenase (COX) inhibitory biflavonoid from the seeds of Semecarpus anacardium J. Ethnopharmacol. 95 209 212 doi:10.1016/j.jep.2004.07.026
31. F. Nantel D. Denis R. Gordon A. Northey M. Cirino K. M. Metters 1999 Distribution and regulation of cyclooxygenase-2in carrageenan-induced inflammation Br. J. Pharmacol. 128 853 859 doi:10.1038/sj.bjp.0702866
32. S. Cuzzocrea A. P. Caputi B. Zingarelli 1998 Peroxynitrite-mediated DNA strand breakage activates poly (ADP-ribose) synthetase and causes cellular energy depletion in carrageenan-induced pleurisy Immunology 93 96 101 doi:10.1046/j.1365-2567.1998.00409.x
33. A. S. Kalgutkar Z. Zhao 2001 Discovery and design of selective cycloxygenase-2 inhibitors as non-ulcerogenic, anti-inflammatory drugs with potential utility as anti-cancer agents Curr. Drug Targets 2 79 106 doi:10.2174/1389450013348830
34. H. Nakagawa K. Sakata 1996 Partial purification and characterization of exudates gelatinase in the acute phase of carrageenan-induced inflammation in rats J. Biochem. 100 1499 1506
35. Tandon, H. 2005. Phytochemicals and cardiovascular health. Current R&D Highlights.
36. L. Giovannelli G. Testa C. De Filippo V. Cheynier M. N. Clifford P. Dolara 2000 Effect of complex polyphenols and tannins from red wine on DNA oxidative damage of rat colon mucosa in vivo Eur. J. Nutr. 39 207 212 doi:10.1007/s003940070013
37. A. A. Eldin M. A. Hamdy A. A. Shaheen T. K. Motawi H. M. Abd el Gawad 1992 Effect of vitamin C administration in modulating some biochemical changes in arthritic rats Pharmacol. Res. 26 357 366 doi:10.1016/1043-6618(92)90234-3
38. H. Hosseinzadeh M. Ramezani G. Salmani 2000 Antinociceptive, antiinflammatory and acute toxicity effects of Zataria multiflora Boiss extracts in mice and rats J. Ethnopharmacol. 73 379 385 doi:10.1016/S0378-8741(00)00238- 5
39. H. Suleyman L. O. Demirezer A. Kuruuzum Z. N. Banoglu F. Gocer G. Ozbakir 1999 Antiinflammatory effect of the aqueous extract from Rumex patientia L. roots J. Ethnopharmacol. 65 141 148 doi:10.1016/S0378-8741(98)00175-5
40. O. A. Olajide S. O. Awe J. M. Makinde A. I. Ekhelar A. Olusola O. Morebise 2000 Studies on the antiinflammatory, antipyretic and analgesic properties of Alstonia boonei stem bark J. Ethnopharmacol. 71 179 186 doi:10.1016/S0378-8741(99)00200-7
41. D. W. Gilroy A. Tomlinson D. A. Willoughby 1998 Differential effects of inhibition of isoforms of cyclooxygenase (COX-1, COX-2) in chronic inflammation Inflamm. Res. 47 79 85 doi:10.1007/s000110050285
42. P. S. Giffen J. Turton C. M. Andrews P. Barrett C. J. Clarke K. W. Fung 2003 Markers of experimental acute inflammation in the Wistar Han rat with particular reference to haptoglobin and C-reactive protein Arch. Toxicol. 77 392 402 doi:10.1007/s00204-003-0458-7
43. G. Kweifo-Okai C. A. Carroll 1993 Antiarthritic effect of lupeol acetate Phytother. Res. 7 213 215 doi:10.1002/ptr.2650070227
44. W. P. Arend J. M. Dayer 1990 Cytokines and cytokine inhibitors or antagonists in rheumatoid arthritis Arthritis Rheum. 33 305 315 doi:10.1002/art.1780330302
45. R. W. Kinne R. Brauer B. Stuhlmuller E. Palombo-Kinne G. R. Burmester 2000 Macrophages in rheumatoid arthritis Arthritis Res. 2 189 202 doi:10.1186/ar86
46. B. J. R. Whittle G. A. Higgs K. E. Eakins S. Moncada J. R. Vane 1980 Selective inhibition of prostaglandin production in inflammatory exudates and gastric mucosa Nature 284 271 273 doi:10.1038/284271a0
47. R. Isii K. Saito M. Horie T. Shibano S. Kitanaka F. Amano 1999 Inhibitory effects of hydrolyzable tannins from Melastoma dodecandrum Lour. on nitric oxide production by a murine macrophage-like cell line, RAW264.7, activated with lipopolysaccharide and interferon-gamma Biol. Pharm. Bull. 22 647 653
48. M. Z. Asmawi H. Kankaanranta E. Moilanen H. Vapaatalo 1993 Antiinflammatory activities of Emblica officinalis Gaertn leaf extracts J. Pharm. Pharmacol. 45 581 584
49. R. H. Davis K. Y. Rosenthal L. R. Cesario G. R. Rouw 1990 Vitamin C influence on localized adjuvant arthritis J. Am. Podiatr. Med. Assoc. 80 414 448