A simple inflammation model that distinguishes between the actions of anti-inflammatory and anti-rheumatic drugs

Inflammation Research

Volumn 47, Issue 1, 1998, Pages 26-35

  Lewis, E J ^a   Bishop, J ^a   Aspinall, S J ^a  

^a ROCHE PRODUCTS LTD   (United Kingdom)

Author keywords

Acute phase protein; Anti inflammatory drugs; Anti rheumatic drugs; Cytokine; Rat

Indexed keywords

ACUTE PHASE PROTEIN; ADJUVANT; ALBUMIN; ANTIINFLAMMATORY AGENT; ANTIRHEUMATIC AGENT; CERULOPLASMIN; CYTOKINE; DEXAMETHASONE; GOLD SALT; HAPTOGLOBIN; IMMUNOMODULATING AGENT; NONSTEROID ANTIINFLAMMATORY AGENT; STEROID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD LEVEL; CENTRIFUGAL ANALYZER; CONTROLLED STUDY; DOSE RESPONSE; FEMALE; INFLAMMATION; NONHUMAN; PAW EDEMA; RAT; SPECTROPHOTOMETRY;

ACUTE-PHASE PROTEINS; ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTIRHEUMATIC AGENTS; ARTHRITIS, EXPERIMENTAL; CERULOPLASMIN; DISEASE MODELS, ANIMAL; FEMALE; HAPTOGLOBINS; INFLAMMATION; MYCOBACTERIUM TUBERCULOSIS; ORGANOGOLD COMPOUNDS; OROSOMUCOID; PREDNISOLONE; RATS; TRIAMCINOLONE;

EID: 0031964474     PISSN: 10233830     EISSN: None     Source Type: Journal    
DOI: 10.1007/s000110050250     Document Type: Article

References (41)

1. Tugwell P, Boers M. OMERACT conference on outcome measures in rheumatoid arthritis clinical trials. J Rheumatol 1993;20:590.
2. Dixon JS. Biochemical and clinical changes in rheumatoid arthritis: Their relation to the action of anti-rheumatoid drugs. Semin Arthritis Rheum 1982;12:191-207.
3. Forster PJG, Grindulis KA, Neumann V, Hubball S, McConkey B. High-dose intravenous methylprednisolone in rheumatoid arthritis. Ann Rheum Dis 1982;41:444-6.
4. McConkey B, Crockson RA, Crockson AP, Wilkinson AR. The effects of some anti-inflammatory drugs on the acute-phase proteins in rheumatoid arthritis. Q J Med 1973;42:785-91.
5. McConkey B, Davies P, Crockson RA, Crockson AP, Butler M, Constable TJ, et al. Effects of gold, dapsone, and prednisolone on serum C-reactive protein and haptoglobin and the erythrocyte sedimentation rate in rheumatoid arthritis. Ann Rheum Dis 1979;38:141-4.
6. Luukkainen R, Kajander A, Isomaki H. Effect of gold on progression of erosions in rheumatoid arthritis. Scand J Rheumatol 1977;6:189-92.
7. Dixon JS, Pickup ME, Lowe JR, Hallett C, Lee MR, Wright V. Discriminatory indices of response of patients with rheumatoid arthritis treated with D-penicillamine. Ann Rheum Dis 1980;39:301-11.
8. Walz DT, DiMartino MJ, Misher A. Adjuvant-induced arthritis in rats II. Drug effects on physiologic, biochemical and immunologic parameters. J Pharmacol Exp Ther 1971;178:223-31.
9. Cannon GW, Smith CB, Cole BC, Ward JR. Effects of weekly and daily pretreatment with gold sodium thiomalate on adjuvant induced arhritis. J Rheumatol 1987;14:202-8.
10. Dunn CJ, Prouteau M, Delahaye M. Purcell T, Branceni D. Prolonged treatment with D-penicillamine: Effects on adjuvant arthritis in the rat. Agents Actions 1984;14:269-73.
11. Aylward M, Maddock J, Wheeldon R, Parker RJ. A study of the influence of various antirheumatic drug regimens on serum acute-phase proteins, plasma tryplophan, and erythrocyte sedimentation rate in rheumatoid arthritis. Rheumatol Rehabil 1975;14:101-14.
12. McConkey B, Crockson RA, Crockson AP. The assessment of rheumatoid arthritis - a study based on measurement of serum acute-phase reactants. Q J Med 1972;41:115-25.
13. Billingham MEJ, Davies GE. Experimental models of arthritis in animals as screening tests for drugs to treat arthritis in man. In: Vane JR, Ferreira SH, editors. Anti-inflammatory Drugs. Handb Exp Pharm 50/II. Berlin: Springer-Verlag, 1979:108-44.
14. Lewis EJ, Bishop J, Cashin CH. Automated quantification of rat plasma acute phase reactants in experimental inflammation. J Pharmacol Methods 1989;21:183-94.
15. Lewis EJ, Sedgwick AD, Hanahoe THP. In vivo changes in plasma acute phase protein levels in the rat induced by slow release of IL-1, IL-6 and TNF. Med Inflam 1992;1:39-44.
16. Newbould BB. Chemotherapy of arthritis induced in rats by Mycobacterial adjuvant. Brit J Pharmacol 1963;21:127-36.
17. Sternberg M, Peyroux J, Engler R, Grochulski A, Leseget C, Lagrue G, et al. Orosomucoid, seromucoid and haptoglobin in serum during adjuvant arthritis in the rat. Experientia 1974;30:193-5.
18. Owen JA, Better FC, Hoban J. A simple method for determination of serum haptoglobins. J Clin Pathol 1960;13:163-4.
19. Sunderman FW Jr, Nomoto S. Measurement of human serum ceruloplasmin by its p-phenylenediamine oxidase activity. Clin Chem 1970;16:903-10.
20. Dow D, Pinto PV. Determination of serum albumin on the SMA-12/30 (hospital model) using bromo-cresol green. Clin Chem 1969;15:1006-8.
21. Mallya RK, de Beer FC, Berry H, Hamilton ED, Mace BE, Pepys MB. Correlation of clinical parameters of disease activity in rheumatoid arthritis with serum concentration of C-reactive protein and erythrocyte sedimentation rate. J Rheumatol 1982;9:224-8.
22. Eastgate JA, Symons JA, Wood NC, Grinlinton FM, di Giovine FS, Duff GW. Correlation of plasma interleukin-1 levels with disease activity in rheumatoid arthritis. Lancet 1988;2:706-9.
23. Burger W, Schade R, Hirschelman R. The rat c-reactive protein - isolation and response to experimental inflammation and tissue damage. Agents Actions 1987;21:93-7.
24. Myers MA, Fleck A. Observations on the delay in onset of the acute phase protein response. Br J Exp Pathol 1988; 69: 169-76.
25. Koj A. Acute phase reactants. In: Allison AC, editor. Structure and Function of Plasma Proteins. London: Plenum Press, 1975: 73-131.
26. Weimer HE, Wood FD, Pearson CM. Serum protein alterations in adjuvant-induced arthritis. Can J Biochem 1968;46:743-8.
27. Milanino R, Moretti U, Concari E, Marrella M, Velo GP. Copper and zinc status in adjuvant-arthritic rat: Studies on blood, liver, kidneys, spleen and inflamed paws. Agents Actions 1988;24:365-76.
28. Weimer HE, Humelbaugh C. Effects of periodic challenge on the response of AP-globulin and other acute phase reactants of rat serum to tissue injury. Can J Biochem 1967;45:241-7.
29. Arend WP, Dayer JM. Cytokines and cytokine inhibitors or antagonists in rheumatoid arthritis. Arthritis Rheum 1990;33: 305-15.
30. Whicher JT, Thompson D, Billingham MEJ, Kitchen EA. Acute phase proteins. In: Pharmacological Methods in the Control of Inflammation. New York: A.R. Liss, 1989:101-28.
31. Baumann H, Gauldie J. The acute phase response. Immunol Today 1994;15:74-80.
32. Marinkovic S, Jahreis GP, Wong GG, Baumann H. IL-6 modulates the synthesis of a specific set of acute phase plasma proteins in vivo. J Biol Chem 1989;142:808-12.
33. Geiger T, Andus T, Klapproth J, Hirano T, Kishimoto T, Heinrich PC. Induction of rat acute-phase proteins by interleukin-6 in vivo. Eur J Immunol 1988;18:717-21.
34. Shalaby MR, Waage A, Aarden L, Espevik T. Endotoxin, tumor necrosis factor-a and interleukin 1 induce interleukin 6 production in vivo. Clin Immunol Immunopathol 1989;53:488-98.
35. Andersson U, Sander B, Anderson J, Moller G. Concomitant production of different lymphokines in activated T cells. Eur J Immunol 1988;18:2081-4.
36. Kampschmidt RF, Jones T. Rate of clearance of interleukin-1 from the blood of normal and nephrectomised rats. Proc Soc Exp Biol Med 1985;180:170-3.
37. Ramadori G, Van Damme J, Rieder H, Meyer zum Buschenfelde KH. Interleukin 6, the third mediator of acute-phase reaction, modulates hepatic protein synthesis in human and mouse. Comparison with interleukin 1 beta and tumor necrosis factor-alpha. Eur J Immunol 1988;18:1259-64.
38. Marinkovic S, Jehreis GP, Wong GG, Baumann H. IL-6 modulates the synthesis of a specific set of acute plasma proteins in vivo. J Immunol 1989;142:808-12.
39. Nijsten MW, de Groot ER, ten Dius HJ, Klasen HZ, Hack CE, Aardeu LA, et al. Serum levels of interleukin-6 and acute phase proteins [letter]. Lancet 1987;2:921.
40. Houssiau FA, Devogelaer JP, Van Damme J, Deuxchaisnes CN, Van Snick J. Interleukin-6 in synovial fluid and serum of patients with rheumatoid arthritis and other inflammatory arthritides, Arthritis Rheum 1988;31:784-8.
41. Westacott CI, Whicher JT, Barnes IC, Thompson D, Swan AJ, Dieppe PA. Synovial fluid concentration of five different cytokines in rheumatic diseases. Ann Rheum Dis 1990;49:676-81.