β-C-Glycosiduronic acids and β-C-glycosyl compounds: New PTP1B inhibitors

Bioorganic and Medicinal Chemistry Letters

Volumn 18, Issue 24, 2008, Pages 6348-6351

  Lin, Li ^a,b   Shen, Qiang ^c   Chen, Guo Rong ^b   Xie, Juan ^a  

^a UNIVERSITÉ PARIS SACLAY   (France)

^b EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^c SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

C Glycosyl compounds; Diabetes; Inhibitor; Protein tyrosine phosphatase 1B; Quinone; Uronic acid

Indexed keywords

PROTEIN TYROSINE PHOSPHATASE 1B INHIBITOR; QUINONE DERIVATIVE; URONIC ACID;

ARTICLE; DIABETES MELLITUS; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; IC 50; STRUCTURE ACTIVITY RELATION;

CARBOHYDRATES; CHEMISTRY, PHARMACEUTICAL; DIABETES MELLITUS; DRUG DESIGN; ENZYME INHIBITORS; GLYCOSIDES; HUMANS; INHIBITORY CONCENTRATION 50; MODELS, CHEMICAL; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 1; QUINONES; STRUCTURE-ACTIVITY RELATIONSHIP; URONIC ACIDS;

EID: 56549087210     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2008.10.091     Document Type: Article

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