Association of CD4 enhancer gene polymorphisms with rheumatoid arthritis and systemic lupus erythematosus in Taiwan

Journal of Rheumatology

Volumn 35, Issue 11, 2008, Pages 2113-2118

  Lo, Sui Foon ^a,b   Wan, Lei ^a,b,c   Lin, Hsiu Chen ^d   Huang, Chung Ming ^a,b   Tsai, Fuu Jen ^a,b,c  

^a CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^b CHINA MEDICAL UNIVERSITY   (Taiwan)

^c ASIA UNIVERSITY   (Taiwan)

^d Department of Medical Laboratory Science and Biotechnology   (Taiwan)

Author keywords

CD4 enhancer; Polymorphism; Rheumatoid arthritis; Systemic lupus erythematosus

Indexed keywords

CD4 ANTIGEN;

ARTICLE; CONTROLLED STUDY; DNA POLYMORPHISM; ENHANCER REGION; GENE FREQUENCY; GENETIC ASSOCIATION; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; RHEUMATOID ARTHRITIS; SYSTEMIC LUPUS ERYTHEMATOSUS; TAIWAN;

ANTIGENS, CD4; ARTHRITIS, RHEUMATOID; ENHANCER ELEMENTS, GENETIC; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; LUPUS ERYTHEMATOSUS, SYSTEMIC; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; RISK FACTORS; SEVERITY OF ILLNESS INDEX; TAIWAN;

EID: 56449089311     PISSN: 0315162X     EISSN: None     Source Type: Journal    
DOI: 10.3899/jrheum.070993     Document Type: Article

References (40)

1. Feldmann M, Brennan FM, Maini RN. Rheumatoid arthritis. Cell 1996;85:307-10.
2. Weyand CM, Klimiuk PA, Goronzy JJ. Heterogeneity of rheumatoid arthritis: from phenotypes to genotypes. Springer Semin Immunopathol 1998;20:5-22.
3. Autoimmunity and autoimmune disease. In: Roitt I, Brostoff J, Male D, editors. Immunology. 6th ed. Edinburgh: Mosby; 2001:401-15.
4. Ehrenstein MR, Evans JG, Singh A, et al. Compromised function of regulatory T cells in rheumatoid arthritis and reversal by anti-TNF therapy. J Exp Med 2004;200:277-85.
5. Crispin JC, Kyttaris VC, Juang YT, Tsokos GC. How signaling and gene transcription aberrations dictate the systemic lupus erythematosus T cell phenotype. Trends Immunol 2008;29:110-5.
6. Rahman A, Isenberg DA. Systemic lupus erythematosus. N Engl J Med 2008;358:929-39.
7. van Roon JAG, Bijlsma JWJ, Lafeber FPJG. Diversity of regulatory T cells to control arthritis. Best Pract Res Clin Rheumatol 2006;20:897-913.
8. Kamradt T, Mitchison NA. Tolerance and autoimmunity. N Engl J Med 2001;344:655-64.
9. Krummel MF, Davis MM. Dynamics of the immunological synapse: finding, establishing and solidifying a connection. Curr Opin Immunol 2002;14:66-74.
10. Wang JH, Meijers R, Xiong Y, et al. Crystal structure of the human CD4 N-terminal two-domain fragment complexed to a class II MHC molecule. Proc Natl Acad Sci USA 2001;98:10799-804.
11. Palacios EH, Weiss A. Function of the Src-family kinases, Lck and Fyn, in T-cell development and activation. Oncogene 2004;23:7990-8000.
12. Irvine DJ, Purbhoo MA, Krogsgaard M, Davis MM. Direct observation of ligand recognition by T cells. Nature 2002;419:845-9.
13. Ansari-Lari MA, Muzny DM, Lu J, et al. A gene-rich cluster between the CD4 and triosephosphate isomerase genes at human chromosome 12p13. Genome Res 1996;6:314-26.
14. Ellmeier W, Sawada S, Littman DR. The regulation of CD4 and CD8 coreceptor gene expression during T cell development. Annu Rev Immunol 1999;17:523-54.
15. Siu G, Wurster AL, Lipsick JS, Hedrick SM. Expression of the CD4 gene requires a Myb transcription factor. Mol Cell Biol 1992;12:1592-604.
16. Jiang H, Peterlin BM. Differential chromatin looping regulates CD4 expression in immature thymocytes. Mol Cell Biol 2008;28:907-12.
17. Yu M, Wan M, Zhang J, Wu J, Khatri R, Chi T. Nucleoprotein structure of the CD4 locus: implications for the mechanisms underlying CD4 regulation during T cell development. Proc Natl Acad Sci USA 2008;105:3873-8.
18. van Zeben D, Hazes JM, Zwinderman AH, et al. Association of HLA-DR4 with a more progressive disease course in patients with rheumatoid arthritis. Results of a follow up study. Arthritis Rheum 1991;34:822-30.
19. Wagner U, Kaltenhauser S, Sauer H, et al. HLA markers and prediction of clinical course and outcome in rheumatoid arthritis. Arthritis Rheum 1997;40:341-51.
20. Graham RR, Ortmann WA, Langefeld CD, et al. Visualizing human leukocyte antigen class II risk haplotypes in human systemic lupus erythematosus. Am J Hum Genet 2002;71:543-53.
21. Fernando MMA, Stevens CR, Sabeti PC, et al. Identification of two independent risk factors for lupus within the MHC in United Kingdom families. PLoS Genet 2007;3:e192.
22. Arnett FC, Edworthy SM, Bloch DA, et al. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 1988;31:315-24.
23. Tan EM, Cohen AS, Fries JF, et al. The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum 1982;25:1271-7.
24. Hochberg MC. Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus [letter]. Arthritis Rheum 1997;40:1725.
25. Yen JH, Chen JR, Tsai WJ, Tsai JJ, Liu HW. HLA-DRB1 genotyping in patients with rheumatoid arthritis in Taiwan. J Rheumatol 1995;22:1450-4.
26. Weyand CM, Goronzy JJ. T-cell responses in rheumatoid arthritis: systemic abnormalities - local disease. Curr Opin Rheumatol 1999;11:210-7.
27. Mottonen M, Heikkinen J, Mustonen L, Isomaki P, Luukkainen R, Lassila O. CD4+ CD25+ T cells with the phenotypic and functional characteristics of regulatory T cells are enriched in the synovial fluid of patients with rheumatoid arthritis. Clin Exp Immunol 2005;140:360-7.
28. Jiao Z, Wang W, Jia R, et al. Accumulation of FoxP3-expressing CD4+CD25+ T cells with distinct chemokine receptors in synovial fluid of patients with active rheumatoid arthritis. Scand J Rheumatol 2007;36:428-33.
29. Liu MF, Wang CR, Fung LL, Wu CR. Decreased CD4+CD25+ T cells in peripheral blood of patients with systemic lupus erythematosus. Scand J Immunol 2004;59:198-202.
30. Alvarado-Sanchez B, Hernandez-Castro B, Portales-Perez D, et al. Regulatory T cells in patients with systemic lupus erythematosus. J Autoimmun 2006;27:110-8.
31. Valencia X, Yarboro C, Illei G, Lipsky PE. Deficient CD4+CD25high T regulatory cell function in patients with active systemic lupus erythematosus. J Immunol 2007;178:2579-88.
32. Vargas-Rojas MI, Crispin JC, Richaud-Patin Y, Alcocer-Varela J. Quantitative and qualitative normal regulatory T cells are not capable of inducing suppression in SLE patients due to T-cell resistance. Lupus 2008;17:289-94.
33. Feito MJ, Ballester S, Diez-Orejas R, et al. CD4 dependence of activation threshold and TCR signaling in mouse T lymphocytes. Scand J Immunol 1997;45:166-74.
34. Ghabanbasani MZ, Buyse I, Legius E, et al. Possible association of CD3 and CD4 polymorphisms with insulin-dependent diabetes mellitus (IDDM). Clin Exp Immunol 1994;97:517-21.
35. Zamani MG, DeHert M, Spaepen M, et al.Study of the possible association of HLA class II, CD4, and CD3 polymorphisms with schizophrenia. Am J Med Genet 1994;54:372-7.
36. Promotors and enhancers. In: Lewin B, editor. Genes VIII. New York: Pearson Prentice Hall; 2004:597-630.
37. Mueller-Storm HP, Sogo JM, Schaffner W. An enhancer stimulates transcription in trans when attached to the promoter via a protein bridge. Cell 1989;58:767-77.
38. Herendeen DR, Kassavetis GA, Geiduschek EP. A transcriptional enhancer whose function imposes a requirement that proteins track along DNA. Science 1992;256:1298-303.
39. Blackwood EM, Kadonaga JT. Going the distance: a current view of enhancer action. Science 1998;281:61-3.
40. Petrascheck M, Escher D, Mahmoudi T, Verrijzer CP, Schaffner W, Barberis A. DNA looping induced by a transcriptional enhancer in vivo. Nucl Acids Res 2005;33:3743-50.