The Protective Effect of CAPE on Hepatic Ischemia/Reperfusion Injury in Rats

Journal of Surgical Research

Volumn 150, Issue 2, 2008, Pages 271-277

  Saavedra Lopes, Milena ^a   Ramalho, Fernando S ^a   Ramalho, Leandra N Z ^a   Andrade Silva, Alessandra ^a   Martinelli, Ana L C ^a   Jordão Jr , Alceu A ^a   Castro e Silva, Orlando ^a   Zucoloto, Sérgio ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

CAPE; I R injury; liver; NF B

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CAFFEIC ACID PHENETHYL ESTER; GLUTATHIONE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; TRANSCRIPTION FACTOR RELA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; LIPID PEROXIDATION; LIVER ISCHEMIA; LIVER PROTECTION; MALE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; PROPHYLAXIS; RAT; REPERFUSION INJURY; TISSUE INJURY;

ALANINE TRANSAMINASE; ANIMALS; APOPTOSIS; ASPARTATE AMINOTRANSFERASES; CAFFEIC ACIDS; GLUTATHIONE; LIPID PEROXIDATION; LIVER; MALE; NEUTROPHILS; NF-KAPPA B; PHENYLETHYL ALCOHOL; RATS; RATS, WISTAR; REPERFUSION INJURY;

EID: 56449085517     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2008.01.039     Document Type: Article

References (36)

1. Serracino-Inglott F., Habib N.A., and Mathie R.T. Hepatic ischemia-reperfusion injury. Am J Surg 181 (2001) 160
2. Casillas-Ramírez A., Mosbah I.B., Ramalho F., et al. Past and future approaches to ischemia-reperfusion lesion with liver transplantation. Life Sci 79 (2006) 1881
3. Jaeschke H. Molecular mechanisms of hepatic ischemia-reperfusion injury and preconditioning. Am J Physiol Gastrointest Liver Physiol 284 (2003) G15
4. Fan C., Zwacka R.M., and Engelhardt J.F. Therapeutic approaches for ischemia/reperfusion injury in the liver. J Mol Med 77 (1999) 577
5. Karin M., and Ben-Neriah Y. Phosphorylation meets ubiquitination: The control of NF-κB activity. Annu Rev Immunol 18 (2000) 621
6. Havsteen B.H. The biochemistry and medical significance of the flavonoids. Pharmacol Ther 96 (2002) 67
7. Gomez-Caravaca A.M., Gomez-Romero M., Arraez-Roman D., et al. Advances in the analysis of phenolic compounds in products derived from bees. J Pharm Biomed Anal 41 (2006) 1220
8. Russo A., Longo R., and Vanella A. Antioxidant activity of propolis: Role of caffeic acid phenethyl ester and galangin. Fitoterapia 73 Suppl 1 (2002) S21
9. Gokalp O., Uz E., Cicek E., et al. Ameliorating role of caffeic acid phenethyl ester (CAPE) against isoniazid-induced oxidative damage in red blood cells. Mol Cell Biochem 290 (2006) 55
10. Michaluart P., Masferrer J.L., Carothers A.M., et al. Inhibitory effects of caffeic acid phenethyl ester on the activity and expression of cyclooxygenase-2 in human oral epithelial cells and in a rat model of inflammation. Cancer Res 59 (1999) 2347
11. Natarajan K., Singh S., Burke Jr. T.R., et al. Caffeic acid phenethyl ester is a potent and specific inhibitor of activation of nuclear transcription factor NFκB. Proc Natl Acad Sci USA 93 (1996) 9090
12. Márquez N., Sancho R., Macho A., et al. Caffeic acid phenethyl ester inhibits T-cell activation by targenting both nuclear factor of activated T-cells and NFκB trancription factors. J Pharmacol Experim Therap 308 (2004) 993
13. Irmak M.K., Koltuksuz U., Kutlu N.O., et al. The effect of caffeic acid phenethyl ester on ischemia-reperfusion injury in comparison with alpha-tocopherol in rat kidneys. Urol Res 29 (2001) 190
14. Ozyurt H., Irmak M.K., Akyol O., et al. Caffeic acid phenethyl ester changes the indices of oxidative stress in serum of rats with renal ischemia-reperfusion injury. Cell Biochem Funct 19 (2001) 259
15. Uz E., Sogut S., Sahin S., et al. The protective role of caffeic acid phenethyl ester (CAPE) on testicular tissue after testicular torsion and detorsion. World J Urol 20 (2002) 264
16. Ilhan A., Koltuksuz U., Ozen S., et al. The effects of caffeic acid phenethyl ester (CAPE) on spinal cord ischemia/reperfusion injury in rabbits. Eur J Cardiothorac Surg 16 (1999) 458
17. Koltuksuz U., Ozen S., Uz E., et al. Caffeic acid phenethyl ester prevents intestinal reperfusion injury in rats. J Pediatr Surg 34 (1999) 1458
18. Khan M., Elango C., Ansari M.A., et al. Caffeic acid phenethyl ester reduces neurovascular inflammation and protects rat brain following transient focal cerebral ischemia. J Neurochem 102 (2007) 365
19. Selzner M., Rüdiger H.A., Sindram D., et al. Mechanisms of ischemic injury are different in the steatotic and normal rat liver. Hepatology 32 (2000) 1280
20. Brigelius R., Muckel C., Akerboom T.P., et al. Identification and quantitation of glutathione in hepatic protein mixed disulfides and its relationship to glutathione disulfide. Biochem Pharmacol 32 (1983) 2529
21. Serafin A., Rosello-Catafau J., Prats N., et al. Ischemic preconditioning increases the tolerance of fatty liver to hepatic ischemia-reperfusion injury in the rat. Am J Pathol 161 (2002) 587
22. Moloney W.C., McPherson K., and Fliegelman L. Esterase activity in leukocytes demonstrated by the use of naphthol AS-D chloroacetate substrate. J Histochem Cytochem 8 (1960) 200
23. Suetsugu Y., Iimuro T., Uehara T., et al. Nuclear factor κB inactivation in the rat liver ameliorates short term total warm ischaemia/reperfusion injury. Gut 54 (2005) 835
24. Yilmaz H.R., Sogut S., Ozyurt B., et al. The activities of liver adenosine deaminase, xanthine oxidase, catalase, superoxide dismutase enzymes and the levels of malondialdehyde and nitric oxide after cisplatin toxicity in rats: Protective effect of caffeic acid phenethyl ester. Toxicol Ind Health 21 (2005) 67
25. Iraz M., Ozerol E., Gulec M., et al. Protective effect of caffeic acid phenethyl ester (CAPE) administration on cisplatin-induced oxidative damage to liver in rat. Cell Biochem Funct 24 (2006) 357
26. Pekmez H., Kus I., Colakoglu N., et al. The protective effects of caffeic acid phenethyl ester (CAPE) against liver damage induced by cigarette smoke inhalation in rats. Cell Biochem Funct 25 (2007) 395
27. Ates B., Dogru M.I., Gul M., et al. Protective role of caffeic acid phenethyl ester in the liver of rats exposed to cold stress. Fundam Clin Pharmacol 20 (2006) 283
28. Mohamadin A.M., Hammad L.N., El-Bab M.F., et al. Attenuation of oxidative stress in plasma and tissues of rats with experimentally induced hyperthyroidism by caffeic acid phenylethyl ester. Basic Clin Pharmacol Toxicol 100 (2007) 84
29. Yilmaz H.R., Uz E., Yucel N., et al. Protective effect of caffeic acid phenethyl ester (CAPE) on lipid peroxidation and antioxidant enzymes in diabetic rat liver. J Biochem Mol Toxicol 18 (2004) 234
30. Sud'ina G.F., Mirzoeva O.K., Pushkareva M.A., et al. Caffeic acid phenethyl ester as a lipoxygenase inhibitor with antioxidant properties. FEBS Lett 329 (1993) 21
31. Bowie A., and O'Neill L.A. Oxidative stress and nuclear factor-kappaB activation: A reassessment of the evidence in the light of recent discoveries. Biochem Pharmacol 59 (2000) 13
32. Abdel-Latif M.M., Windle H.J., Homasany B.S., et al. Caffeic acid phenethyl ester modulates Helicobacter pylori-induced nuclear factor-kappa B and activator protein-1 expression in gastric epithelial cells. Br J Pharmacol 146 (2005) 1139
33. Yoshidome H., Kato A., Edwards M.J., et al. Interleukin-10 suppresses hepatic ischemia/reperfusion injury in mice: Implications of a central role for nuclear factor kappa B. Hepatology 30 (1999) 203
34. Gu X.P., Qiu Y.D., Xu F.T., et al. In vivo suppressive effect of nuclear factor-kappaB inhibitor on neutrophilic inflammation of grafts after orthotopic liver transplantation in rats. World J Gastroenterol 10 (2004) 3654
35. Xu M.Q., Shuai X.R., Yan M.L., et al. Nuclear factor-kappaB decoy oligodeoxynucleotides attenuates ischemia/reperfusion injury in rat liver graft. World J Gastroenterol 11 (2005) 6960
36. Tsuchihashi S., Tamaki T., Tanaka M., et al. Pyrrolidine dithiocarbamate provides protection against hypothermic preservation and transplantation injury in the rat liver: The role of heme oxygenase-1. Surgery 133 (2003) 556