Substitution of HIV type 1 Nef with HTLV-1 p12

AIDS Research and Human Retroviruses

Volumn 20, Issue 9, 2004, Pages 938-943

  Tsukahara, Tomonori ^a,b   Ratner, Lee ^a,c  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b SHINSHU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c WASHINGTON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NEF PROTEIN; PROTEIN P12; UNCLASSIFIED DRUG; VIRUS PROTEIN;

ARTICLE; CELL DIVISION; CELL IMMORTALIZATION; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN T CELL LEUKEMIA VIRUS 1; LYMPHOCYTE; MACROPHAGE; NONHUMAN; OPEN READING FRAME; PRIORITY JOURNAL; PROTEIN EXPRESSION; RETROVIRUS; VIRUS INFECTIVITY; VIRUS PATHOGENESIS; VIRUS REPLICATION;

CELLS, CULTURED; GENE PRODUCTS, NEF; HELA CELLS; HIV-1; HUMANS; MACROPHAGES; ONCOGENE PROTEINS, VIRAL; RECEPTORS, CCR5; RECOMBINANT PROTEINS; TRANSCRIPTION FACTORS; VIRUS REPLICATION;

EID: 5644303001     PISSN: 08892229     EISSN: None     Source Type: Journal    
DOI: 10.1089/aid.2004.20.938     Document Type: Article

References (37)

1. Hinuma Y, Nagata K, Hanaoka M, Nakai M, Matsumoto T, Kinoshita KI, Shirakawa S, and Miyoshi I: Adult T-cell leukemia: Antigen in an ATL cell line and detection of antibodies to the antigen in human sera. Proc Natl Acad Sci USA 1981;78:6476-6480.
2. Poiesz BJ, Ruscetti FW, Gazdar AF, Bunn PA, Minna JD, and Gallo RC: Detection and isolation of type C retrovirus particles from fresh and cultured lymphocytes of a patient with cutaneous T-cell lymphoma. Proc Natl Acad Sci USA 1980;77:7415-7419.
3. Yoshida M: Multiple viral strategies of HTLV-1 for dysregulation of cell growth control. Annu Rev Immunol 2001;19:475-496.
4. Albrecht B and Lairmore MD: Critical role of human T-lymphotropic virus type 1 accessory proteins in viral replication and pathogenesis. Microbiol Mol Biol Rev 2002;66:396-406.
5. Albrecht B, D'Souza CD, Ding W, Tridandapani S, Coggeshall KM, and Lairmore MD: Activation of nuclear factor of activated T cells by human T-lymphotropic virus type 1 accessory protein p12(I). J Virol 2002;76:3493-3501.
6. Ding W, Albrecht B, Kelley RE, Muthusamy N, Kim SJ, Altschuld RA, and Lairmore MD: Human T-cell lymphotropic virus type 1 p12(I) expression increases cytoplasmic calcium to enhance the activation of nuclear factor of activated T cells. J Virol 2002;76: 10374-10382.
7. Nicot C, Mulloy JC, Ferrari MG, Johnson JM, Fu K, Fukumoto R, Trovato R, Fullen J, Leonard WJ, and Franchini G: HTLV-1 p12(I) protein enhances STAT5 activation and decreases the interleukin-2 requirement for proliferation of primary human peripheral blood mononuclear cells. Blood 2001;98:823-829.
8. Robek MD, Wong FH, and Ratner L: Human T-cell leukemia virus type 1 pX-I and pX-II open reading frames are dispensable for the immortalization of primary lymphocytes. J Virol 1998;72:4458-4462.
9. Albrecht B, Collins ND, Burniston MT, Nisbet JW, Ratner L, Green PL, and Lairmore MD: Human T-lymphotropic virus type 1 open reading frame I p12(I) is required for efficient viral infectivity in primary lymphocytes. J Virol 2000;74:9828-9835.
10. Collins ND, Newbound GC, Albrecht B, Beard JL, Ratner L, and Lairmore MD: Selective ablation of human T-cell lymphotropic virus type 1 p12I reduces viral infectivity in vivo. Blood 1998;91:4701-4707.
11. Fackler OT and Baur AS: Live and let die: Nef functions beyond HIV replication. Immunity 2002;16:493-497.
12. Geyer M, Fackler OT, and Peterlin BM: Structure-function relationships in HIV-1 Nef. EMBO Rep 2001;2:580-585.
13. Arold S, Franken P, Strub MP, Hoh F, Benichou S, Benarous R, and Dumas C: The crystal structure of HIV-1 Nef protein bound to the Fyn kinase SH3 domain suggests a role for this complex in altered T cell receptor signaling. Structure 1997;5:1361-1372.
14. Grzesiek S, Bax A, Clore GM, Gronenborn AM, Hu JS, Kaufman J, Palmer I, Stahl SJ, and Wingfield PT: The solution structure of HIV-1 Nef reveals an unexpected fold and permits delineation of the binding surface for the SH3 domain of Hck tyrosine protein kinase. Nat Struct Biol 1996;3:340:345.
15. Manninen A, Renkema GH, and Saksela K: Synergistic activation of NFAT by HIV-1 nef and the Ras/MAPK pathway. J Biol Chem 2000;275:1651-1657.
16. Kestler HW, Ringler DJ, Mori K, Panicali DL, Sehgal PK, Daniel MD, and Desrosiers RC: Importance of the nef gene for maintenance of high virus loads and for development of AIDS. Cell 1991;65:651-662.
17. Spina CA, Kwoh TJ, Chowers MY, Guatelli JC, and Richman DD: The importance of nef in the induction of human immunodeficiency virus type 1 replication from primary quiescent CD4 lymphocytes. J Exp Med 1994;179:115-123.
18. Niederman TM, Thielan BJ, and Ratner L: Human immunodeficiency virus type 1 negative factor is a transcriptional silencer. Proc Natl Acad Sci USA 1989;86:1128-1132.
19. Bryant M and Ratner L: Myristoylation-dependent replication and assembly of human immunodeficiency virus 1. Proc Natl Acad Sci USA 1990;87:523-527.
20. Tsukahara T, Wielgosz MM, and Ratner L: Characterization of envelope glycoprotein mutants for human T-cell leukemia virus type 1 infectivity and immortalization. J Virol 2001;75:9553-9559.
21. Tsukahara T, Kannagi M, Ohashi T, Kato H, Arai M, Nunez G, Iwanaga Y, Yamamoto N, Ohtani K, Nakamura M, and Fujii M: Induction of Bcl-x(L) expression by human T-cell leukemia virus type 1 Tax through NF-kappaB in apoptosis-resistant T-cell transfectants with Tax. J Virol 1999;73:7981-7987.
22. Pirounaki M, Heyden NA, Arens M, and Ratner L: Rapid phenotype drug susceptibility assay for HIV-1 with a CCR5 expressing indicator cell line. J Virol Methods 2000;85:151-161.
23. Westervelt P, Gendelman HE, and Ratner L: Identification of a determinant within the human immunodeficiency virus 1 surface envelope glycoprotein critical for productive infection of primary monocytes. Proc Natl Acad Sci USA 1991;88:3097-3101.
24. Huang Y, Zhang L, and Ho DD: Biological characterization of nef in long-term survivors of human immunodeficiency virus type 1 infection. J Virol 1995;69:8142-8146.
25. Miller MD, Warmerdam MT, Gaston I, Greene WC, and Feinberg MB: The human immunodeficiency virus-1 nef gene product: a positive factor for viral infection and replication in primary lymphocytes and macrophages. J Exp Med 1994;179:101-113.
26. Papkalla A, Munch J, Otto C, and Kirchhoff F: Nef enhances human immunodeficiency virus type 1 infectivity and replication independently of viral coreceptor tropism. J Virol 2002;76: 8455-8459.
27. Schaeffer E, Geleziunas R, and Greene WC: Human immunodeficiency virus type 1 Nef functions at the level of virus entry by enhancing cytoplasmic delivery of virions. J Virol 2001;75:2993-3000.
28. Aiken C and Trono D: Nef stimulates human immunodeficiency virus type 1 proviral DNA synthesis. J Virol 1995;69:5048-5056.
29. Chowers MY, Pandori MW, Spina CA, Richman DD, and Guatelli JC: The growth advantage conferred by HIV-1 nef is determined at the level of viral DNA formation and is independent of CD4 downregulation. Virology 1995;212:451-457.
30. Wiskerchen M and Cheng-Mayer C: HIV-1 Nef association with cellular serine kinase correlates with enhanced virion infectivity and efficient proviral DNA synthesis. Virology 1996;224:292-301.
31. Schrager JA and Marsh JW: HIV-1 Nef increases T cell activation in a stimulus-dependent manner. Proc Natl Acad Sci USA 1999; 96:8167-8172.
32. Schibeci SD, Clegg AO, Biti RA, Sagawa K, Stewart GJ, and Williamson P: HIV-Nef enhances interleukin-2 production and phosphatidylinositol 3-kinase activity in a human T cell line. AIDS 2000;14:1701-1707.
33. Geleziunas R, Xu W, Takeda K, Ichigo H, and Green WC: HIV-1 Nef inhibits ASK1-dependent death signaling providing a potential mechanism for protecting the infected host cell. Nature 2001;410:834-838.
34. Xu XN, Laffert B, Screaton GR, Kraft M, Wolf D, Kolanus W, Mongkolsapay J, McMichael AJ, and Baur AS: Induction of Fas ligand expression by HIV involves the interaction of Nef with the T cell receptor zeta chain. J Exp Med 1999;189:1489-1496.
35. Schattner EJ: Apoptosis in lymphocytic leukemias and lymphomas. Cancer Invest 2002;20:737-748.
36. Ding W, Albrecht B, Luo R, Zhang W, Stanley JR, Newbound GC, and Lairmore MD: Endoplasmic reticulum and cis-Golgi localization of human T-lymphotropic virus type 1 p12(I): Association with calreticulin and calnexin. J Virol 2001;75:7672-7682.
37. Alexander M, Bar YC, Ravichandran KS, Hammarskjald ML, and Rekash DL: Human immunodeficiency virus type 1 nef associates with lipid rafts to downmodulate cell surface CD4 and class I major histocompatibility complex expression and to increase viral infectivity. J Virol 2004;78:1685-1696.