The effects of agouti-related protein gene transfer in vivo by electroporation in mice

Neuroscience Letters

Volumn 370, Issue 2-3, 2004, Pages 108-113

  Xiang, Lan ^a   Murai, Atsushi ^a   Muramatsu, Tatsuo ^a  

^a NAGOYA UNIVERSITY   (Japan)

Author keywords

Agouti related protein; Body weight; Food intake; In vivo electroporation

Indexed keywords

AGOUTI RELATED PROTEIN; COMPLEMENTARY DNA; MESSENGER RNA;

ARTICLE; BODY WEIGHT; CONCENTRATION RESPONSE; CONTROLLED STUDY; ELECTROPORATION; FOOD INTAKE; GENE TRANSFER; GENETIC CODE; HYPOTHALAMUS; IN VIVO STUDY; LIVESTOCK; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SKELETAL MUSCLE;

ANIMALS; BLOTTING, WESTERN; BODY WEIGHT; EATING; ELECTROPORATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; GENE TRANSFER TECHNIQUES; GREEN FLUORESCENT PROTEINS; HUMANS; HYPOTHALAMUS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MICE; MICE, INBRED ICR; MUSCLES; NEUROPEPTIDE Y; ORGAN SIZE; PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TIME FACTORS;

EID: 5644251894     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2004.08.010     Document Type: Article

References (23)

1. K. Baran, E. Preston, D. Wilks, G.J. Cooney, E.W. Kraegen, and A. Sainsbury Chronic central melanocortin-4 receptor antagonism and central neuopeptide-Y infusion in rat produce increased adiposity by divergent pathways Diabetes 51 2002 152 158
2. C. Broberger, C. Johanson, M. Schalling, and T. Hokfelt The neuropeptide Y/agouti-related protein (AGRP) brain circuitry in normal, anorectic, and monosodium glutamate-treated mice Proc. Natl. Acad. Sci. U.S.A. 95 1998 15043 15048
3. W. Fan, B.A. Boston, R.A. Kesterson, V.J. Hruby, and R.D. Cone Role of melanocortinergic neurons in feeding and the agouti obesity syndrome Nature 385 1997 165 168
4. T.M. Fong, C. Mao, T. Mac Neil, R. Kalyani, T. Smith, D. Weinberg, M.R. Tota, and L.H.T. Vande Ploeg ART as an antagonism of MC-3 and MC-4 receptor Biochem. Biophys. Res. Commun. 200 1997 1214 1220
5. M. Graham, U. Shutter, I. Sargsi, and K.L. Stark Overexpression of AGRP leads to obesity in transgenic mice Nat. Genet. 17 1997 273 274
6. C. Grunfeid, C. Zhao, J. Fuller, A. Pollock, A. Moser, J. Friedman, and K.R. Feingold Endotoxin and cytokines induce expression of leptin, the ob gene product, in hamsters J. Clin. Invest. 97 1996 2152 2157
7. M.M. Hagan, P.A. Rushing, L.M. Pritchard, M.W. Schwartz, A.M. Strack, L.H. van der Ploeg, S.C. Woods, and R.L. Seeley Long-term orexigenic effects of Agrp-(83-132) involve mechanisms other than melanocortin receptor blockade Am. J. Physiol. 279 2001 R47 R52
8. C. Hasskell-Luevano, S. Lim, W. Yuan, R. Cone, and V.J. Hruby Structure activity studies of the melanocortin antagonist SHU9119 modified at the 6, 7, 8, 9 position Peptides 21 2000 49 57
9. C. Hasskell-Luevano, and E.K. Monck Agouti-related protein function as an inverse agonist at a constitutively active brain melanocortin-4 receptor Regul. Pept. 99 2001 1 7
10. D. Huszar, C.A. Lynch, V. Fairchild-Huntress, J.H. Dunmore, F.J. Smith, and R.A. Kesterson Targeted disruption of the melanocortin-4 receptor results in obesity in mice Cell 88 1997 131 141
11. A.J. Kastin, V. Akerstrom, and L. Hackler Agouti-related protein (83-132) aggregates and crosses the blood-brain barrier slowly Metabolism 49 2000 1444 1448
12. A. Katsuki, Y. Sumida, E.C. Gabazza, S. Murashima, T. Tanaka, M. Furuta, R. Araki-Sasaki, Y. Hori, K. Nakatani, Y. Yano, and Y. Adachi Plasma levels of agouti-related protein are increased in obese men J. Clin. Endocrinol. Metab. 86 2001 1921 1924
13. D. Lu, D. Willard, I.R. Patel, S. Kadwell, L. Oveeton, and T. Kost Agouti protein is an antagonist of the melanocyte-stimulating-hormone receptor Nature 371 1994 799 802
14. M.M. Ollmann, B.D. Wilson, Y.-K. Yang, J.A. Kern, Y. Chen, I. Gantz, and G. Barsh Antagonism of central melanocortin receptors in vitro and in vivo by agouti-related protein Science 278 1997 135 138
15. J.M. Quillan, W. Sadee, E.T. Wei, C.C. Jimenez, L. Ji, and J.K. Chang Chemical synthesis of an active agouti related protein fragment, JKC-358: a potent inhibitor of the melanocortin receptor FEBS Lett. 428 1998 59 62
16. P. Sarraf, R.C. Frederich, E.M. Turner, G. Ma, N.T. Jaskowiak, D.J. Rivet III, J.S. Flier, B.B. Lowell, D.L. Fraker, and H.R. Alexander Multiple cytokines and acute inflammation raise mouse leptin levels: potential role in inflammatory anorexia J. Exp. Med. 185 1997 171 175
17. C.P. Shen, K.K. Wu, L.P. Shearman, R. Camacho, M.R. Tota, T.M. Fong, and L.H. Van der Ploeg Plasma agouti-related protein level: a possible correlation with fasted and fed states in humans and rats J. Neuroendocrinol. 14 2002 607 610
18. J.R. Shutter, M. Graham, A.C. Kinsey, S. Scully, and K.L. Stark Hypothalamic expression of ART, a novel gene related to agouti, is up-regulated in obese and diabetic mutant mice Gene Dev. 11 1997 593 602
19. C.J. Small, M.S. Kim, S.A. Stanley, J.R.D. Mitchell, K. Murphy, D.G.A. Morgan, M.A. Ghatei, and S.R. Bloom Effects of chronic central nervous system administration of agouti related protein in pair-fed animals Diabetes 50 2001 248 252
20. S. Takeuchi, K. Teshigawara, and S. Takahashi Widespread expression of agouti-related protein (AGRP) in the chicken: a possible involvement of AGRP in regulating peripheral melanocortin systems in the chicken Biochim. Biophys. Acta. 1496 2000 261 269
21. L. Xiang, A. Murai, K. Sugahara, A. Yasui, and T. Muramatsu Effects of leptin gene expression in mice in vivo by electroporation and hydrodynamics-based gene delivery Biochem. Biophys. Res. Commun. 307 2003 440 445
22. Y.-K. Yang, D.A. Thompson, C.J. Dickinson, G.S. Wilken, G.S. Barsh, and S.B.H. Kent Characterization of agouti related protein binding to melanocortin receptors Mol. Endocrinol. 13 1999 148 155
23. H. Zheng, M.M. Corkem, S.M. Crousillac, L.M. Patterson, C.B. Phifer, and H.R. Berthoud Neurochemical phenotype of hypothalamic neurons showing Fos expression 23 h after intracranial AgRP Am. J. Physiol. 282 2002 R1773 R1781