In vitro and in vivo characterization of porous poly-L-lactic acid coatings for subcutaneously implanted glucose sensors

Journal of Biomedical Materials Research - Part A

Volumn 87, Issue 3, 2008, Pages 792-807

  Koschwanez, H E ^a   Yap, F Y ^a   Klitzman, B ^a,b   Reichert, W M ^a  

^a Duke University   (United States)

^b DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Glucose sensors; in vivo; PLLA; Porous; Subcutaneous

Indexed keywords

ACIDS; AMMONIUM COMPOUNDS; BODY FLUIDS; COATINGS; ENZYME SENSORS; GLUCOSE; LACTIC ACID; LEACHING; ORGANIC ACIDS; ORGANIC POLYMERS; POLYMER BLENDS; SENSORS;

AMMONIUM BICARBONATES; BENEFICIAL EFFECTS; COLLAGEN DEPOSITIONS; IN VITRO; IN VIVO; L-LACTIC ACIDS; LEACHING AGENTS; MECHANICAL STRESSES; PLLA; POROUS; POROUS COATINGS; POROUS POLIES; RESPONSE RATES; SENSOR ACCURACIES; SENSOR RESPONSES; SENSOR SURFACES; SUBCUTANEOUS;

GLUCOSE SENSORS;

AMMONIUM BICARBONATE; BICARBONATE; GLUCOSE; POLYLACTIC ACID; UNCLASSIFIED DRUG; AMMONIA; BIOMATERIAL; LACTIC ACID; POLYMER;

ACCURACY; ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOSENSOR; COLLAGEN SYNTHESIS; CONTROLLED STUDY; FIBROSIS; GLUCOSE TRANSDUCER; HISTOLOGY; IMPLANT; IN VITRO STUDY; IN VIVO STUDY; MATERIAL COATING; MICROVASCULATURE; NONHUMAN; RAT; SUBCUTANEOUS TISSUE; SURFACE PROPERTY; TISSUE REACTION; VASCULARIZATION; CYTOTOXICITY; DEGRADATION; DENSITY; HYDRATION; IMPLANTATION; MASS SPECTROMETRY; MECHANICAL STRESS; POROSITY; SCANNING ELECTRON MICROSCOPY; SENSOR; ANIMAL; CHEMISTRY; GENETIC PROCEDURES; GLUCOSE BLOOD LEVEL; INSTRUMENTATION; MALE; SPRAGUE DAWLEY RAT;

ANIMALS; BIOSENSING TECHNIQUES; BLOOD GLUCOSE; COATED MATERIALS, BIOCOMPATIBLE; LACTIC ACID; MALE; POLYMERS; POROSITY; RATS; RATS, SPRAGUE-DAWLEY; SURFACE PROPERTIES;

EID: 56349144842     PISSN: 15493296     EISSN: 15524965     Source Type: Journal    
DOI: 10.1002/jbm.a.31824     Document Type: Article

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