Simvastatin inducing PC3 prostate cancer cell necrosis mediated by calcineurin and mitochondrial dysfunction

Journal of Bioenergetics and Biomembranes

Volumn 40, Issue 4, 2008, Pages 307-314

  Oliveira, Kívia A P ^a   Zecchin, Karina G ^a   Alberici, Luciane C ^a   Castilho, Roger F ^a   Vercesi, Aníbal E ^a  

^a UNIVERSITY OF CAMPINAS   (Brazil)

Author keywords

Apoptosis; Cell death; Intracellular calcium homeostasis; Mitochondrial permeability transition; Statin

Indexed keywords

BONGKREKIC ACID; CALCINEURIN; CYCLOSPORIN A; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; MEVALONIC ACID; SIMVASTATIN; TACROLIMUS;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL DEATH; CELL PROLIFERATION; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DRUG ANTAGONISM; DRUG EFFECT; DRUG INHIBITION; DRUG SENSITIVITY; ENZYME INHIBITION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; PROSTATE CANCER;

APOPTOSIS; CALCINEURIN; CELL LINE, TUMOR; CELL PROLIFERATION; HUMANS; MALE; MITOCHONDRIA; MITOCHONDRIAL MEMBRANE TRANSPORT PROTEINS; PROSTATIC NEOPLASMS; SIMVASTATIN;

EID: 56349138037     PISSN: 0145479X     EISSN: 15736881     Source Type: Journal    
DOI: 10.1007/s10863-008-9155-9     Document Type: Article

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