Mutagenesis of the murine cytomegalovirus M56 terminase gene

Journal of General Virology

Volumn 89, Issue 11, 2008, Pages 2864-2868

  Wang, Jian Ben ^a   McVoy, Michael A ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE; EPITOPE; PROTEIN M56; PROTEIN M56A; UNCLASSIFIED DRUG; VIRUS ENZYME;

AMINO TERMINAL SEQUENCE; ARTICLE; BACTERIAL ARTIFICIAL CHROMOSOME; CONTROLLED STUDY; CYTOMEGALOVIRUS; ENZYME ACTIVITY; FRAMESHIFT MUTATION; GENE DELETION; GENE LOCUS; GENE TARGETING; MOLECULAR CLONING; MOUSE; MUTAGENESIS; NONHUMAN; OPEN READING FRAME; PRIORITY JOURNAL; VIRUS REPLICATION; VIRUS VIABILITY; WILD TYPE;

BASE SEQUENCE; CHROMOSOMES, ARTIFICIAL, BACTERIAL; CYTOMEGALOVIRUS; DNA PRIMERS; DNA, VIRAL; ENDODEOXYRIBONUCLEASES; GENOME, VIRAL; MOLECULAR SEQUENCE DATA; MUTAGENESIS; VIRAL PROTEINS;

BACTERIA (MICROORGANISMS); MAIZE CHLOROTIC MOTTLE VIRUS; MIRIDAE; MURID HERPESVIRUS 1;

EID: 56349111498     PISSN: 00221317     EISSN: None     Source Type: Journal    
DOI: 10.1099/vir.0.2008/003137-0     Document Type: Article

References (26)

1. Black L. W. (1989). DNA packaging in dsDNA bacteriophages. Annu Rev Microbiol 43, 267-292.
2. Brown, J. C., McVoy, M. A. & Homa, F. L. (2002). Packaging DNA into herpesvirus capsids. In Structure-Function Relationships of Human Pathogenic Viruses, pp. 111-154. Edited by A. Holzenburg & E. Bogner. New York: Kluwer Academic/Plenum Publishers.
3. Catalano, C. E (2000). The terminase enzyme from bacteriophage lambda: a DNA-packaging machine. Cell Mol Life Sci 57, 128-148.
4. Cui, X., McGregor, A., Schleiss, M. R. & McVoy, M. A. (2008). Cloning the complete guinea pig cytomegalovirus genome as an infectious bacterial artificial chromosome with excisable origin of replication. J Virol Methods 149, 231-239.
5. Davison, A. J. (1992). Channel catfish virus: a new type of herpesvirus. Virology 186, 9-14.
6. Feiss, M. & Catalano, C. E. (2005). Bacteriophage lambda terminase and the mechanisms of viral DNA packaging. In Viral Genome Packaging Machines: Genetics, Structure and Mechanism, pp. 5-39. Edited by C. E. Catalano. Austin, TX: Landes Biosciences.
7. Hahn, G., Jarosch, M., Wang, J. B., Berbes, C. & McVoy, M. A. (2003). Tn7-mediated introduction of DNA sequences into bacmid-doned cytomegalovirus genomes for rapid recombinant virus construction. J Virol Methods 107, 185-194.
8. Hwang, J. S. & Bogner, E. (2002). ATPase activity of the terminase subunit pUL56 of human cytomegalovirus. J Biol Chem 277, 6943-6948.
9. Hwang, J. S., Kregler, O., Schilf, R., Bannert, N., Drach, J. C., Townsend, L. B. & Bogner, E. (2007). Identification of acetylated, tetrahalogenated benzimidazole D-ribonucleosides with enhanced activity against human cytomegalovirus. J Virol 81, 11604-11611.
10. Krosky, P. M., Ptak, R. G., Underwood, M. R., Biron, K. K., Townsend, L. B. & Drach, J. C. (2000). Differences in DNA packaging genes and sensitivity to benzimidazole ribonucleosides between human cytomegalovirus strains AD 169 and Towne. Antivir Chem Chemother 11, 349-352.
11. Luckow, V. A., Lee, S. C., Barry, G. F. & Olins, P. O. (1993). Efficient generation of infectious recombinant baculoviruses by site-specific transposon-mediated insertion of foreign genes into a baculovirus genome propagated in Escherichia coli. J Virol 67, 4566-4579.
12. McGeoch, D. J., Rixon, F. J. & Davison, A. J. (2006). Topics in herpesvirus genomics and evolution. Virus Res 117, 90-104.
13. McVoy, M. A., Nixon, D. E., Adler, S. P. & Mocarski, E. S. (1998). Sequences within the herpesvirus-conserved pac1 and pac2 motifs are required for cleavage and packaging of the murine cytomegalovirus genome. J Virol 72, 48-56.
14. Mitchell, M. S., Matsuzaki, S., Imai, S. & Rao, V. B. (2002). Sequence analysis of bacteriophage T4 DNA packaging/terminase genes 16 and 17 reveals a common ATPase center in the large subunit of viral terminases. Nucleic Acids Res 30, 4009-4021.
15. Przech, A. J., Yu, D. & Weller, S. K. (2003). Point mutations in exon I of the herpes simplex virus putative terminase subunit, UL15, indicate that the most conserved residues are essential for cleavage and packaging. J Virol 77, 9613-9621.
16. Rao, V. B. & Black, L. W. (2005). DNA Packaging in Bacteriophage T4. In Viral Genome Packaging Machines: Genetics, Structure, and Mechanism, pp. 40-58. Edited by C. E. Catalano. Austin, TX: Landes Biosciences.
17. Reefschlaeger, J., Bender, W., Hallenberger, S., Weber, O., Eckenberg, P., Goldmann, S., Haerter, M., Buerger, I., Trappe, J. & other authors (2001). Novel non-nucleoside inhibitors of cytomegaloviruses (BAY 38-4766): in vitro and in vivo antiviral activity and mechanism of action. J Antimicrob Chemother 48, 757-767.
18. Scholz, B., Rechter, S., Drach, J. C., Townsend, L. B. & Bogner, E. (2003). Identification of the ATP-binding site in the terminase subunit pUL56 of human cytomegalovirus. Nucleic Acids Res 31, 1426-1433.
19. Underwood, M. R., Harvey, R. J., Stanat, S. C., Hemphill, M. L., Miller, T., Drach, J. C., Townsend, L. B. & Biron, K. K. (1998). Inhibition of human cytomegalovirus DNA maturation by a benzimidazole ribonucleoside is mediated through the UL89 gene product. J Virol 72, 717-725.
20. Underwood, M. R., Ferris, R. G., Selleseth, D. W., Davis, M. G., Drach, J. C., Townsend, L. B., Biron, K. K. & Boyd, F. L. (2004). Mechanism of action of the ribopyranoside benzimidazole GW275175X against human cytomegalovirus. Antimicrob Agents Chemother 48, 1647-1651.
21. van Zeijl, M., Fairhurst, J., Jones, T. R., Vernon, S. K., Morin, J., LaRocque, J., Feld, B., O'Hara, B., Bloom, J. D. & Johann, S. V. (2000). Novel class of thiourea compounds that inhibit herpes simplex virus type 1 DNA cleavage and encapsidation: resistance maps to the UL6 gene. J Virol 74, 9054-9061.
22. Varnum, S. M., Streblow, D. N., Monroe, M. E., Smith, P., Auberry, K. J., Pasa-Tolic, L., Wang, D., Camp, D. G., II, Rodiand, K. & other authors (2004). Identification of proteins in human cytomegalovirus (HCMV) particles: the HCMV proteome. J Virol 78, 10960-10966.
23. Walker, J. E., Saraste, M., Runswick M. J. & Gay, N. J. (1982). Distantly related sequences in the α- and β-subunits of ATP synthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold. EMBO J 1, 945-951.
24. Wang, J. B., Nixon, D. E. & McVoy, M. A. (2008). Definition of the minimal cis-acting sequences necessary for genome maturation of the herpesvirus murine cytomegalovirus. J Virol 82, 2394-2404.
25. Yu, D. & Weller, S. K. (1998). Genetic analysis of the UL15 gene locus for the putative terminase of herpes simplex virus type 1. Virology 243, 32-44.
26. Yu, D., Ellis, H. M., Lee, E. C., Jenkins, N. A., Copeland, N. G. & Court, D. L. (2000). An efficient recombination system for chromosome engineering in Escherichia coli. Proc Natl Acad Sci U S A 97, 5978-5983.