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Volumn 18, Issue 5, 2008, Pages 472-478

Timing cell-fate determination during asymmetric cell divisions

Author keywords

[No Author keywords available]

Indexed keywords

CELL COMMUNICATION; CELL CYCLE PROGRESSION; CELL DIFFERENTIATION; CELL DIVISION; CELL FATE; CELL ORGANELLE; CELL POLARITY; CELL PROLIFERATION; CELL RENEWAL; CELL STRUCTURE; CELL TYPE; CENTROSOME; DAUGHTER CELL; GLIA CELL; GOLGI COMPLEX; MEMBRANE RECONSTITUTION; MITOSIS; MOLECULAR BIOLOGY; NERVE CELL; NERVOUS SYSTEM DEVELOPMENT; NEUROBLAST; PERIPHERAL NERVOUS SYSTEM; PRIORITY JOURNAL; REVIEW; STEM CELL;

EID: 56249138246     PISSN: 09594388     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.conb.2008.10.005     Document Type: Review
Times cited : (20)

References (48)
  • 1
    • 0345362965 scopus 로고    scopus 로고
    • Revisiting the Drosophila microchaete lineage: a novel intrinsically asymmetric cell division generates a glial cell
    • Gho M., Bellaiche Y., and Schweisguth F. Revisiting the Drosophila microchaete lineage: a novel intrinsically asymmetric cell division generates a glial cell. Development 126 (1999) 3573-3584
    • (1999) Development , vol.126 , pp. 3573-3584
    • Gho, M.1    Bellaiche, Y.2    Schweisguth, F.3
  • 2
    • 0030579127 scopus 로고    scopus 로고
    • The embryonic central nervous system lineages of Drosophila melanogaster. I. Neuroblast lineages derived from the ventral half of the neuroectoderm
    • Bossing T., Udolph G., Doe C.Q., and Technau G.M. The embryonic central nervous system lineages of Drosophila melanogaster. I. Neuroblast lineages derived from the ventral half of the neuroectoderm. Dev Biol 179 (1996) 41-64
    • (1996) Dev Biol , vol.179 , pp. 41-64
    • Bossing, T.1    Udolph, G.2    Doe, C.Q.3    Technau, G.M.4
  • 3
    • 0032707248 scopus 로고    scopus 로고
    • Clonal analysis of Drosophila embryonic neuroblasts: neural cell types, axon projections and muscle targets
    • Schmid A., Chiba A., and Doe C.Q. Clonal analysis of Drosophila embryonic neuroblasts: neural cell types, axon projections and muscle targets. Development 126 (1999) 4653-4689
    • (1999) Development , vol.126 , pp. 4653-4689
    • Schmid, A.1    Chiba, A.2    Doe, C.Q.3
  • 4
    • 40549128664 scopus 로고    scopus 로고
    • Amplification of neural stem cell proliferation by intermediate progenitor cells in Drosophila brain development
    • Bello B.C., Izergina N., Caussinus E., and Reichert H. Amplification of neural stem cell proliferation by intermediate progenitor cells in Drosophila brain development. Neural Dev 3 (2008) 5
    • (2008) Neural Dev , vol.3 , pp. 5
    • Bello, B.C.1    Izergina, N.2    Caussinus, E.3    Reichert, H.4
  • 6
    • 42149188826 scopus 로고    scopus 로고
    • Distinct behaviors of neural stem and progenitor cells underlie cortical neurogenesis
    • •], this paper provides a detailed analysis of the division patterns of neural progenitor cells and the relationship between the orientation of the mitotic spindle and the fates of the two daughter cells during mammalian neurogenesis.
    • •], this paper provides a detailed analysis of the division patterns of neural progenitor cells and the relationship between the orientation of the mitotic spindle and the fates of the two daughter cells during mammalian neurogenesis.
    • (2008) J Comp Neurol , vol.508 , pp. 28-44
    • Noctor, S.C.1    Martinez-Cerdeno, V.2    Kriegstein, A.R.3
  • 7
    • 43949137061 scopus 로고    scopus 로고
    • Neural stem cells: balancing self-renewal with differentiation
    • Doe C.Q. Neural stem cells: balancing self-renewal with differentiation. Development 135 (2008) 1575-1587
    • (2008) Development , vol.135 , pp. 1575-1587
    • Doe, C.Q.1
  • 8
    • 39149130360 scopus 로고    scopus 로고
    • Mechanisms of asymmetric stem cell division
    • Knoblich J.A. Mechanisms of asymmetric stem cell division. Cell 132 (2008) 583-597
    • (2008) Cell , vol.132 , pp. 583-597
    • Knoblich, J.A.1
  • 9
    • 45049086846 scopus 로고    scopus 로고
    • Neurogenesis and asymmetric cell division
    • Zhong W., and Chia W. Neurogenesis and asymmetric cell division. Curr Opin Neurobiol 18 (2008) 4-11
    • (2008) Curr Opin Neurobiol , vol.18 , pp. 4-11
    • Zhong, W.1    Chia, W.2
  • 10
    • 0032516178 scopus 로고    scopus 로고
    • Frizzled signalling controls orientation of asymmetric sense organ precursor cell divisions in Drosophila
    • Gho M., and Schweisguth F. Frizzled signalling controls orientation of asymmetric sense organ precursor cell divisions in Drosophila. Nature 393 (1998) 178-181
    • (1998) Nature , vol.393 , pp. 178-181
    • Gho, M.1    Schweisguth, F.2
  • 11
    • 0035839053 scopus 로고    scopus 로고
    • The partner of inscuteable/discs-large complex is required to establish planar polarity during asymmetric cell division in Drosophila
    • Bellaiche Y., Radovic A., Woods D.F., Hough C.D., Parmentier M.L., O'Kane C.J., Bryant P.J., and Schweisguth F. The partner of inscuteable/discs-large complex is required to establish planar polarity during asymmetric cell division in Drosophila. Cell 106 (2001) 355-366
    • (2001) Cell , vol.106 , pp. 355-366
    • Bellaiche, Y.1    Radovic, A.2    Woods, D.F.3    Hough, C.D.4    Parmentier, M.L.5    O'Kane, C.J.6    Bryant, P.J.7    Schweisguth, F.8
  • 12
    • 0035913905 scopus 로고    scopus 로고
    • Heterotrimeric G proteins direct two modes of asymmetric cell division in the Drosophila nervous system
    • Schaefer M., Petronczki M., Dorner D., Forte M., and Knoblich J.A. Heterotrimeric G proteins direct two modes of asymmetric cell division in the Drosophila nervous system. Cell 107 (2001) 183-194
    • (2001) Cell , vol.107 , pp. 183-194
    • Schaefer, M.1    Petronczki, M.2    Dorner, D.3    Forte, M.4    Knoblich, J.A.5
  • 13
    • 0037428199 scopus 로고    scopus 로고
    • Apical complex genes control mitotic spindle geometry and relative size of daughter cells in Drosophila neuroblast and pI asymmetric divisions
    • Cai Y., Yu F., Lin S., Chia W., and Yang X. Apical complex genes control mitotic spindle geometry and relative size of daughter cells in Drosophila neuroblast and pI asymmetric divisions. Cell 112 (2003) 51-62
    • (2003) Cell , vol.112 , pp. 51-62
    • Cai, Y.1    Yu, F.2    Lin, S.3    Chia, W.4    Yang, X.5
  • 14
    • 2642620243 scopus 로고    scopus 로고
    • Binary sibling neuronal cell fate decisions in the Drosophila embryonic central nervous system are nonstochastic and require inscuteable-mediated asymmetry of ganglion mother cells
    • Buescher M., Yeo S.L., Udolph G., Zavortink M., Yang X., Tear G., and Chia W. Binary sibling neuronal cell fate decisions in the Drosophila embryonic central nervous system are nonstochastic and require inscuteable-mediated asymmetry of ganglion mother cells. Genes Dev 12 (1998) 1858-1870
    • (1998) Genes Dev , vol.12 , pp. 1858-1870
    • Buescher, M.1    Yeo, S.L.2    Udolph, G.3    Zavortink, M.4    Yang, X.5    Tear, G.6    Chia, W.7
  • 15
    • 0028802562 scopus 로고
    • Asymmetric localization of numb autonomously determines sibling neuron identity in the Drosophila CNS
    • Spana E.P., Kopczynski C., Goodman C.S., and Doe C.Q. Asymmetric localization of numb autonomously determines sibling neuron identity in the Drosophila CNS. Development 121 (1995) 3489-3494
    • (1995) Development , vol.121 , pp. 3489-3494
    • Spana, E.P.1    Kopczynski, C.2    Goodman, C.S.3    Doe, C.Q.4
  • 16
    • 0031473198 scopus 로고    scopus 로고
    • Segregation of myogenic lineages in Drosophila requires numb
    • Ruiz Gomez M., and Bate M. Segregation of myogenic lineages in Drosophila requires numb. Development 124 (1997) 4857-4866
    • (1997) Development , vol.124 , pp. 4857-4866
    • Ruiz Gomez, M.1    Bate, M.2
  • 17
    • 0033972640 scopus 로고    scopus 로고
    • Multiple signalling pathways establish cell fate and cell number in Drosophila malpighian tubules
    • Wan S., Cato A.M., and Skaer H. Multiple signalling pathways establish cell fate and cell number in Drosophila malpighian tubules. Dev Biol 217 (2000) 153-165
    • (2000) Dev Biol , vol.217 , pp. 153-165
    • Wan, S.1    Cato, A.M.2    Skaer, H.3
  • 18
    • 0030199973 scopus 로고    scopus 로고
    • Control of daughter cell fates during asymmetric division: interaction of Numb and Notch
    • Guo M., Jan L.Y., and Jan Y.N. Control of daughter cell fates during asymmetric division: interaction of Numb and Notch. Neuron 17 (1996) 27-41
    • (1996) Neuron , vol.17 , pp. 27-41
    • Guo, M.1    Jan, L.Y.2    Jan, Y.N.3
  • 19
    • 0030199995 scopus 로고    scopus 로고
    • Numb antagonizes Notch signaling to specify sibling neuron cell fates
    • Spana E.P., and Doe C.Q. Numb antagonizes Notch signaling to specify sibling neuron cell fates. Neuron 17 (1996) 21-26
    • (1996) Neuron , vol.17 , pp. 21-26
    • Spana, E.P.1    Doe, C.Q.2
  • 20
    • 0027947609 scopus 로고
    • Asymmetric distribution of numb protein during division of the sensory organ precursor cell confers distinct fates to daughter cells
    • Rhyu M.S., Jan L.Y., and Jan Y.N. Asymmetric distribution of numb protein during division of the sensory organ precursor cell confers distinct fates to daughter cells. Cell 76 (1994) 477-491
    • (1994) Cell , vol.76 , pp. 477-491
    • Rhyu, M.S.1    Jan, L.Y.2    Jan, Y.N.3
  • 23
    • 0030200217 scopus 로고    scopus 로고
    • Asymmetric localization of a mammalian numb homolog during mouse cortical neurogenesis
    • Zhong W., Feder J.N., Jiang M.M., Jan L.Y., and Jan Y.N. Asymmetric localization of a mammalian numb homolog during mouse cortical neurogenesis. Neuron 17 (1996) 43-53
    • (1996) Neuron , vol.17 , pp. 43-53
    • Zhong, W.1    Feder, J.N.2    Jiang, M.M.3    Jan, L.Y.4    Jan, Y.N.5
  • 24
    • 0031000210 scopus 로고    scopus 로고
    • Differential expression of mammalian Numb. Numblike and Notch1 suggests distinct roles during mouse cortical neurogenesis
    • Zhong W., Jiang M.M., Weinmaster G., Jan L.Y., and Jan Y.N. Differential expression of mammalian Numb. Numblike and Notch1 suggests distinct roles during mouse cortical neurogenesis. Development 124 (1997) 1887-1897
    • (1997) Development , vol.124 , pp. 1887-1897
    • Zhong, W.1    Jiang, M.M.2    Weinmaster, G.3    Jan, L.Y.4    Jan, Y.N.5
  • 25
    • 0037206889 scopus 로고    scopus 로고
    • Progenitor cell maintenance requires numb and numblike during mouse neurogenesis
    • Petersen P.H., Zou K., Hwang J.K., Jan Y.N., and Zhong W. Progenitor cell maintenance requires numb and numblike during mouse neurogenesis. Nature 419 (2002) 929-934
    • (2002) Nature , vol.419 , pp. 929-934
    • Petersen, P.H.1    Zou, K.2    Hwang, J.K.3    Jan, Y.N.4    Zhong, W.5
  • 26
    • 3342938070 scopus 로고    scopus 로고
    • Continuing role for mouse Numb and Numbl in maintaining progenitor cells during cortical neurogenesis
    • Petersen P.H., Zou K., Krauss S., and Zhong W. Continuing role for mouse Numb and Numbl in maintaining progenitor cells during cortical neurogenesis. Nat Neurosci 7 (2004) 803-811
    • (2004) Nat Neurosci , vol.7 , pp. 803-811
    • Petersen, P.H.1    Zou, K.2    Krauss, S.3    Zhong, W.4
  • 27
    • 11844271439 scopus 로고    scopus 로고
    • Targeted deletion of numb and numblike in sensory neurons reveals their essential functions in axon arborization
    • Huang E.J., Li H., Tang A.A., Wiggins A.K., Neve R.L., Zhong W., Jan L.Y., and Jan Y.N. Targeted deletion of numb and numblike in sensory neurons reveals their essential functions in axon arborization. Genes Dev 19 (2005) 138-151
    • (2005) Genes Dev , vol.19 , pp. 138-151
    • Huang, E.J.1    Li, H.2    Tang, A.A.3    Wiggins, A.K.4    Neve, R.L.5    Zhong, W.6    Jan, L.Y.7    Jan, Y.N.8
  • 28
    • 33947729578 scopus 로고    scopus 로고
    • The mammalian Golgi regulates numb signaling in asymmetric cell division by releasing ACBD3 during mitosis
    • This paper provides evidence for a novel mechanism in mammals that uses the process of Golgi fragmentation and reconstitution to precisely coordinate cell-cycle progression and cell-fate specification, thereby allowing a cell-fate determinant like Numb to play multiple roles during asymmetric cell divisions.
    • Zhou Y., Atkins J.B., Rompani S.B., Bancescu D.L., Petersen P.H., Tang H., Zou K., Stewart S.B., and Zhong W. The mammalian Golgi regulates numb signaling in asymmetric cell division by releasing ACBD3 during mitosis. Cell 129 (2007) 163-178. This paper provides evidence for a novel mechanism in mammals that uses the process of Golgi fragmentation and reconstitution to precisely coordinate cell-cycle progression and cell-fate specification, thereby allowing a cell-fate determinant like Numb to play multiple roles during asymmetric cell divisions.
    • (2007) Cell , vol.129 , pp. 163-178
    • Zhou, Y.1    Atkins, J.B.2    Rompani, S.B.3    Bancescu, D.L.4    Petersen, P.H.5    Tang, H.6    Zou, K.7    Stewart, S.B.8    Zhong, W.9
  • 30
    • 34548024889 scopus 로고    scopus 로고
    • Mitosis controls the Golgi and the Golgi controls mitosis
    • Colanzi A., and Corda D. Mitosis controls the Golgi and the Golgi controls mitosis. Curr Opin Cell Biol 19 (2007) 386-393
    • (2007) Curr Opin Cell Biol , vol.19 , pp. 386-393
    • Colanzi, A.1    Corda, D.2
  • 31
    • 0036441193 scopus 로고    scopus 로고
    • Golgi architecture and inheritance
    • Shorter J., and Warren G. Golgi architecture and inheritance. Annu Rev Cell Dev Biol 18 (2002) 379-420
    • (2002) Annu Rev Cell Dev Biol , vol.18 , pp. 379-420
    • Shorter, J.1    Warren, G.2
  • 32
    • 0037013167 scopus 로고    scopus 로고
    • Fragmentation and dispersal of the pericentriolar Golgi complex is required for entry into mitosis in mammalian cells
    • Sutterlin C., Hsu P., Mallabiabarrena A., and Malhotra V. Fragmentation and dispersal of the pericentriolar Golgi complex is required for entry into mitosis in mammalian cells. Cell 109 (2002) 359-369
    • (2002) Cell , vol.109 , pp. 359-369
    • Sutterlin, C.1    Hsu, P.2    Mallabiabarrena, A.3    Malhotra, V.4
  • 33
    • 0031460148 scopus 로고    scopus 로고
    • The mechanism of Golgi segregation during mitosis is cell type-specific
    • Stanley H., Botas J., and Malhotra V. The mechanism of Golgi segregation during mitosis is cell type-specific. Proc Natl Acad Sci U S A 94 (1997) 14467-14470
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 14467-14470
    • Stanley, H.1    Botas, J.2    Malhotra, V.3
  • 34
    • 33646027006 scopus 로고    scopus 로고
    • Asymmetric segregation of the tumor suppressor brat regulates self-renewal in Drosophila neural stem cells
    • Betschinger J., Mechtler K., and Knoblich J.A. Asymmetric segregation of the tumor suppressor brat regulates self-renewal in Drosophila neural stem cells. Cell 124 (2006) 1241-1253
    • (2006) Cell , vol.124 , pp. 1241-1253
    • Betschinger, J.1    Mechtler, K.2    Knoblich, J.A.3
  • 35
    • 33645525794 scopus 로고    scopus 로고
    • Brat is a Miranda cargo protein that promotes neuronal differentiation and inhibits neuroblast self-renewal
    • Lee C.Y., Wilkinson B.D., Siegrist S.E., Wharton R.P., and Doe C.Q. Brat is a Miranda cargo protein that promotes neuronal differentiation and inhibits neuroblast self-renewal. Dev Cell 10 (2006) 441-449
    • (2006) Dev Cell , vol.10 , pp. 441-449
    • Lee, C.Y.1    Wilkinson, B.D.2    Siegrist, S.E.3    Wharton, R.P.4    Doe, C.Q.5
  • 36
    • 0032538334 scopus 로고    scopus 로고
    • Partner of Numb colocalizes with Numb during mitosis and directs Numb asymmetric localization in Drosophila neural and muscle progenitors
    • Lu B., Rothenberg M., Jan L.Y., and Jan Y.N. Partner of Numb colocalizes with Numb during mitosis and directs Numb asymmetric localization in Drosophila neural and muscle progenitors. Cell 95 (1998) 225-235
    • (1998) Cell , vol.95 , pp. 225-235
    • Lu, B.1    Rothenberg, M.2    Jan, L.Y.3    Jan, Y.N.4
  • 37
    • 0031789943 scopus 로고    scopus 로고
    • Miranda localizes staufen and prospero asymmetrically in mitotic neuroblasts and epithelial cells in early Drosophila embryogenesis
    • Matsuzaki F., Ohshiro T., Ikeshima-Kataoka H., and Izumi H. Miranda localizes staufen and prospero asymmetrically in mitotic neuroblasts and epithelial cells in early Drosophila embryogenesis. Development 125 (1998) 4089-4098
    • (1998) Development , vol.125 , pp. 4089-4098
    • Matsuzaki, F.1    Ohshiro, T.2    Ikeshima-Kataoka, H.3    Izumi, H.4
  • 38
    • 0032525787 scopus 로고    scopus 로고
    • Miranda as a multidomain adapter linking apically localized Inscuteable and basally localized Staufen and Prospero during asymmetric cell division in Drosophila
    • Shen C.P., Knoblich J.A., Chan Y.M., Jiang M.M., Jan L.Y., and Jan Y.N. Miranda as a multidomain adapter linking apically localized Inscuteable and basally localized Staufen and Prospero during asymmetric cell division in Drosophila. Genes Dev 12 (1998) 1837-1846
    • (1998) Genes Dev , vol.12 , pp. 1837-1846
    • Shen, C.P.1    Knoblich, J.A.2    Chan, Y.M.3    Jiang, M.M.4    Jan, L.Y.5    Jan, Y.N.6
  • 39
    • 29244469948 scopus 로고    scopus 로고
    • Microtubule-induced Pins/Galphai cortical polarity in Drosophila neuroblasts
    • Siegrist S.E., and Doe C.Q. Microtubule-induced Pins/Galphai cortical polarity in Drosophila neuroblasts. Cell 123 (2005) 1323-1335
    • (2005) Cell , vol.123 , pp. 1323-1335
    • Siegrist, S.E.1    Doe, C.Q.2
  • 40
    • 0035931874 scopus 로고    scopus 로고
    • cdc2 links the Drosophila cell cycle and asymmetric division machineries
    • Tio M., Udolph G., Yang X., and Chia W. cdc2 links the Drosophila cell cycle and asymmetric division machineries. Nature 409 (2001) 1063-1067
    • (2001) Nature , vol.409 , pp. 1063-1067
    • Tio, M.1    Udolph, G.2    Yang, X.3    Chia, W.4
  • 41
    • 52949115363 scopus 로고    scopus 로고
    • Linking cell cycle to asymmetric division: Aurora-A phosphorylates the Par complex to regulate Numb localization
    • This paper shows that a phosphorylation cascade triggered by Aurora-A as cell cycle progresses is responsible for asymmetrically localizing Numb during asymmetric divisions by Drosophila neural precursor cells.
    • Wirtz-Peitz F., Nishimura T., and Knoblich J.A. Linking cell cycle to asymmetric division: Aurora-A phosphorylates the Par complex to regulate Numb localization. Cell 135 (2008) 161-173. This paper shows that a phosphorylation cascade triggered by Aurora-A as cell cycle progresses is responsible for asymmetrically localizing Numb during asymmetric divisions by Drosophila neural precursor cells.
    • (2008) Cell , vol.135 , pp. 161-173
    • Wirtz-Peitz, F.1    Nishimura, T.2    Knoblich, J.A.3
  • 42
    • 33746544622 scopus 로고    scopus 로고
    • Mitotic activation of the kinase Aurora-A requires its binding partner Bora
    • This paper provides evidence that Bora activates Aurora-A through direct binding and a Cdc2-dependent mechanism that relocates Bora from the nucleus to the cytoplasm at the onset of mitosis.
    • Hutterer A., Berdnik D., Wirtz-Peitz F., Zigman M., Schleiffer A., and Knoblich J.A. Mitotic activation of the kinase Aurora-A requires its binding partner Bora. Dev Cell 11 (2006) 147-157. This paper provides evidence that Bora activates Aurora-A through direct binding and a Cdc2-dependent mechanism that relocates Bora from the nucleus to the cytoplasm at the onset of mitosis.
    • (2006) Dev Cell , vol.11 , pp. 147-157
    • Hutterer, A.1    Berdnik, D.2    Wirtz-Peitz, F.3    Zigman, M.4    Schleiffer, A.5    Knoblich, J.A.6
  • 43
    • 34548486689 scopus 로고    scopus 로고
    • Polo inhibits progenitor self-renewal and regulates Numb asymmetry by phosphorylating Pon
    • This paper provides evidence that the cell-cycle regulator Polo kinase regulates asymmetric cell division by neuroblasts at least partly through phosphorylating Pon to affect the asymmetric localization and function of the cell-fate determinant Numb.
    • Wang H., Ouyang Y., Somers W.G., Chia W., and Lu B. Polo inhibits progenitor self-renewal and regulates Numb asymmetry by phosphorylating Pon. Nature 449 (2007) 96-100. This paper provides evidence that the cell-cycle regulator Polo kinase regulates asymmetric cell division by neuroblasts at least partly through phosphorylating Pon to affect the asymmetric localization and function of the cell-fate determinant Numb.
    • (2007) Nature , vol.449 , pp. 96-100
    • Wang, H.1    Ouyang, Y.2    Somers, W.G.3    Chia, W.4    Lu, B.5
  • 44
    • 33845704687 scopus 로고    scopus 로고
    • Aurora-A acts as a tumor suppressor and regulates self-renewal of Drosophila neuroblasts
    • Wang H., Somers G.W., Bashirullah A., Heberlein U., Yu F., and Chia W. Aurora-A acts as a tumor suppressor and regulates self-renewal of Drosophila neuroblasts. Genes Dev 20 (2006) 3453-3463
    • (2006) Genes Dev , vol.20 , pp. 3453-3463
    • Wang, H.1    Somers, G.W.2    Bashirullah, A.3    Heberlein, U.4    Yu, F.5    Chia, W.6
  • 45
    • 0030667028 scopus 로고    scopus 로고
    • The N terminus of the Drosophila Numb protein directs membrane association and actin-dependent asymmetric localization
    • Knoblich J.A., Jan L.Y., and Jan Y.N. The N terminus of the Drosophila Numb protein directs membrane association and actin-dependent asymmetric localization. Proc Natl Acad Sci U S A 94 (1997) 13005-13010
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 13005-13010
    • Knoblich, J.A.1    Jan, L.Y.2    Jan, Y.N.3
  • 46
    • 44649117902 scopus 로고    scopus 로고
    • Centrosome amplification can initiate tumorigenesis in flies
    • This paper provides evidence that centrosome amplification initiates tumorigenesis not by causing genome instability but through defects in asymmetric cell division.
    • Basto R., Brunk K., Vinadogrova T., Peel N., Franz A., Khodjakov A., and Raff J.W. Centrosome amplification can initiate tumorigenesis in flies. Cell 133 (2008) 1032-1042. This paper provides evidence that centrosome amplification initiates tumorigenesis not by causing genome instability but through defects in asymmetric cell division.
    • (2008) Cell , vol.133 , pp. 1032-1042
    • Basto, R.1    Brunk, K.2    Vinadogrova, T.3    Peel, N.4    Franz, A.5    Khodjakov, A.6    Raff, J.W.7
  • 47
    • 33846607211 scopus 로고    scopus 로고
    • Asymmetric inheritance of mother versus daughter centrosome in stem cell division
    • This paper provides evidence that Drosophila male GSCs nonrandomly segregate the mother and daughter centrosomes during self-renewing asymmetric cell divisions.
    • Yamashita Y.M., Mahowald A.P., Perlin J.R., and Fuller M.T. Asymmetric inheritance of mother versus daughter centrosome in stem cell division. Science 315 (2007) 518-521. This paper provides evidence that Drosophila male GSCs nonrandomly segregate the mother and daughter centrosomes during self-renewing asymmetric cell divisions.
    • (2007) Science , vol.315 , pp. 518-521
    • Yamashita, Y.M.1    Mahowald, A.P.2    Perlin, J.R.3    Fuller, M.T.4
  • 48
    • 38749152406 scopus 로고    scopus 로고
    • Asymmetric centrosome behavior and the mechanisms of stem cell division
    • Yamashita Y.M., and Fuller M.T. Asymmetric centrosome behavior and the mechanisms of stem cell division. J Cell Biol 180 (2008) 261-266
    • (2008) J Cell Biol , vol.180 , pp. 261-266
    • Yamashita, Y.M.1    Fuller, M.T.2


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