Synthesis and cytotoxic activities of 1-benzylidine substituted β-carboline derivatives

Bioorganic and Medicinal Chemistry Letters

Volumn 18, Issue 24, 2008, Pages 6558-6561

  Cao, Rihui ^a   Yi, Wei ^a   Wu, Qifeng ^a   Guan, Xiangdong ^a   Feng, Manxiu ^a   Ma, Chunming ^a   Chen, Zhiyong ^a   Song, Huacan ^a   Peng, Wenlie ^a  

^a SUN YAT SEN UNIVERSITY   (China)

Author keywords

Carbolines; Cytotoxic activities; Harmine; Structure activity relationships

Indexed keywords

1 BENZYLIDINE BETA CARBOLINIUM BROMATE DERIVATIVE; 1 BENZYLIDINE DERIVATIVE; BENZYLIDENE DERIVATIVE; BETA CARBOLINE DERIVATIVE; CYTOTOXIC AGENT; UNCLASSIFIED DRUG;

ARTICLE; BENZYLATION; CELL STRAIN HEPG2; DRUG CYTOTOXICITY; DRUG POTENCY; DRUG SYNTHESIS; HELA CELL; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTINEOPLASTIC AGENTS; CARBOLINES; CELL LINE, TUMOR; CHEMISTRY, PHARMACEUTICAL; DRUG DESIGN; DRUG SCREENING ASSAYS, ANTITUMOR; HARMINE; HELA CELLS; HUMANS; INHIBITORY CONCENTRATION 50; IONS; MODELS, CHEMICAL; MOLECULAR STRUCTURE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 56249113377     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2008.10.043     Document Type: Article

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