-
1
-
-
33745906528
-
Retinoblastoma tumor suppressor: Where cancer meets the cell cycle
-
Knudsen, E.S. and Knudsen, K.E. Retinoblastoma tumor suppressor: where cancer meets the cell cycle. Exp Biol Med (Maywood) 2006, 231(7): 1271-81.
-
(2006)
Exp Biol Med (Maywood)
, vol.231
, Issue.7
, pp. 1271-1281
-
-
Knudsen, E.S.1
Knudsen, K.E.2
-
2
-
-
0031724929
-
Raf-1 physically interacts with Rb and regulates its function: A link between mitogenic signaling and cell cycle regulation
-
Wang, S., Ghosh, R.N. and Chellappan, S.P. Raf-1 physically interacts with Rb and regulates its function: a link between mitogenic signaling and cell cycle regulation. Mol Cell Biol 1998, 18(12): 7487-98.
-
(1998)
Mol Cell Biol
, vol.18
, Issue.12
, pp. 7487-7498
-
-
Wang, S.1
Ghosh, R.N.2
Chellappan, S.P.3
-
3
-
-
33746672599
-
Nicotine induces cell proliferation by beta-arrestin-mediated activation of Src and Rb-Raf-1 pathways
-
Dasgupta, P., Rastogi, S., Pillai, S., Ordonez-Ercan, D., Morris, M., Haura, E. and Chellappan S. Nicotine induces cell proliferation by beta-arrestin-mediated activation of Src and Rb-Raf-1 pathways. J Clin Invest 2006, 116(8): 2208-2217.
-
(2006)
J Clin Invest
, vol.116
, Issue.8
, pp. 2208-2217
-
-
Dasgupta, P.1
Rastogi, S.2
Pillai, S.3
Ordonez-Ercan, D.4
Morris, M.5
Haura, E.6
Chellappan, S.7
-
4
-
-
0028967830
-
Cyclin D1 oncoprotein aberrantly accumulates in malignancies of diverse histogenesis
-
Bartkova, J., Lukas, J., Strauss, M. and Bartek, J. Cyclin D1 oncoprotein aberrantly accumulates in malignancies of diverse histogenesis. Oncogene 1995, 10(4): 775-8.
-
(1995)
Oncogene
, vol.10
, Issue.4
, pp. 775-778
-
-
Bartkova, J.1
Lukas, J.2
Strauss, M.3
Bartek, J.4
-
5
-
-
0030064902
-
Cyclin D1 gene amplification in human laryngeal squamous cell carcinomas: Prognostic significance and clinical implications
-
Bellacosa, A., Almadori, G., Cavallo, S. et al. Cyclin D1 gene amplification in human laryngeal squamous cell carcinomas: prognostic significance and clinical implications. Clin Cancer Res 1996, 2(1): 175-80.
-
(1996)
Clin Cancer Res
, vol.2
, Issue.1
, pp. 175-180
-
-
Bellacosa, A.1
Almadori, G.2
Cavallo, S.3
-
6
-
-
0028331092
-
Amplification and overexpression of cyclin D1 in breast cancer detected by immunohistochemical staining
-
Gillett, C., Fantl, V., Smith, R. et al. Amplification and overexpression of cyclin D1 in breast cancer detected by immunohistochemical staining. Cancer Res 1994, 54(7): 1812-7.
-
(1994)
Cancer Res
, vol.54
, Issue.7
, pp. 1812-1817
-
-
Gillett, C.1
Fantl, V.2
Smith, R.3
-
7
-
-
0031049383
-
Amplification and expression of the cyclin D1 gene in anal and esophageal squamous cell carcinomas
-
Sheyn, I., Noffsinger, A.E., Heffelfinger, S., Davis, B., Miller, M.A. and Fenoglio-Preiser, C.M. Amplification and expression of the cyclin D1 gene in anal and esophageal squamous cell carcinomas. Hum Pathol 1997, 28(3): 270-6.
-
(1997)
Hum Pathol
, vol.28
, Issue.3
, pp. 270-276
-
-
Sheyn, I.1
Noffsinger, A.E.2
Heffelfinger, S.3
Davis, B.4
Miller, M.A.5
Fenoglio-Preiser, C.M.6
-
8
-
-
9444248167
-
Clinicopathologic study of PRAD1/cyclin D1 overexpressing lymphoma with special reference to mantle cell lymphoma. A distinct molecular pathologic entity
-
Yatabe, Y., Nakamura, S., Seto, M. et al. Clinicopathologic study of PRAD1/cyclin D1 overexpressing lymphoma with special reference to mantle cell lymphoma. A distinct molecular pathologic entity. Am J Surg Pathol 1996, 20(9): 1110-22.
-
(1996)
Am J Surg Pathol
, vol.20
, Issue.9
, pp. 1110-1122
-
-
Yatabe, Y.1
Nakamura, S.2
Seto, M.3
-
9
-
-
0028865984
-
Immunohistochemical detection of the cyclin-dependent kinase inhibitor 2/multiple tumor suppressor gene 1 (CDKN2/MTS1) product p161NK4A in archival human solid tumors: Correlation with retinoblastoma protein expression
-
Geradts, J., Kratzke, R.A., Niehans, G.A. and Lincoln, C.E. Immunohistochemical detection of the cyclin-dependent kinase inhibitor 2/multiple tumor suppressor gene 1 (CDKN2/MTS1) product p161NK4A in archival human solid tumors: correlation with retinoblastoma protein expression. Cancer Res 1995, 55 (24): 6006-11.
-
(1995)
Cancer Res
, vol.55
, Issue.24
, pp. 6006-6011
-
-
Geradts, J.1
Kratzke, R.A.2
Niehans, G.A.3
Lincoln, C.E.4
-
10
-
-
0029665043
-
Rb and p16INK4a expression in resected non-small cell lung tumors
-
Kratzke, R.A., Greatens, T.M., Rubins, J.B., Maddaus, M.A., Niewoehner, D.E., Niehans, G.A. and Geradts, J. Rb and p16INK4a expression in resected non-small cell lung tumors. Cancer Res 1996, 56(15): 3415-20.
-
(1996)
Cancer Res
, vol.56
, Issue.15
, pp. 3415-3420
-
-
Kratzke, R.A.1
Greatens, T.M.2
Rubins, J.B.3
Maddaus, M.A.4
Niewoehner, D.E.5
Niehans, G.A.6
Geradts, J.7
-
11
-
-
0028172926
-
Absence of p16INK4 protein is restricted to the subset of lung cancer lines that retains wildtype RB
-
Ottetson, G.A., Kratzke, R.A., Coxon, A., Kim, Y.W. and Kaye, F.J. Absence of p16INK4 protein is restricted to the subset of lung cancer lines that retains wildtype RB. Oncogene 1994, 9(11): 3375-8.
-
(1994)
Oncogene
, vol.9
, Issue.11
, pp. 3375-3378
-
-
Ottetson, G.A.1
Kratzke, R.A.2
Coxon, A.3
Kim, Y.W.4
Kaye, F.J.5
-
12
-
-
0029971843
-
Inversely correlated expression of p16 and Rb protein in non-small cell lung cancers: An immunohistochemical study
-
Sakaguchi, M., Fujii, Y., Hirabayashi, H. et al. Inversely correlated expression of p16 and Rb protein in non-small cell lung cancers: an immunohistochemical study. Int J Cancer 1996, 65(4): 442-5.
-
(1996)
Int J Cancer
, vol.65
, Issue.4
, pp. 442-445
-
-
Sakaguchi, M.1
Fujii, Y.2
Hirabayashi, H.3
-
13
-
-
0028961521
-
Reciprocal Rb inactivation and p16INK4 expression in primary lung cancers and cell lines
-
Shapiro, G.I., Edwards, C.D., Kobzik, L., Godleski, J., Richards, W., Sugarbaker, D.J. and Rollins, B.J. Reciprocal Rb inactivation and p16INK4 expression in primary lung cancers and cell lines. Cancer Res 1995, 55(3): 505-9.
-
(1995)
Cancer Res
, vol.55
, Issue.3
, pp. 505-509
-
-
Shapiro, G.I.1
Edwards, C.D.2
Kobzik, L.3
Godleski, J.4
Richards, W.5
Sugarbaker, D.J.6
Rollins, B.J.7
-
14
-
-
0024535228
-
The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product
-
Dyson, N., Howley, P.M., Münger, K. and Harlow, E. The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product. Science 1989, 243(4893): 934-7.
-
(1989)
Science
, vol.243
, Issue.4893
, pp. 934-937
-
-
Dyson, N.1
Howley, P.M.2
Münger, K.3
Harlow, E.4
-
15
-
-
0024809865
-
Complex formation of human papillomavirus E7 proteins with the retinoblastoma tumor suppressor gene product
-
Münger, K., Werness, B.A., Dyson, N., Phelps, W.C., Harlow, E. and Howley, P.M. Complex formation of human papillomavirus E7 proteins with the retinoblastoma tumor suppressor gene product. EMBO J 1989, 8(13): 4099-105.
-
(1989)
EMBO J
, vol.8
, Issue.13
, pp. 4099-4105
-
-
Münger, K.1
Werness, B.A.2
Dyson, N.3
Phelps, W.C.4
Harlow, E.5
Howley, P.M.6
-
16
-
-
0031178212
-
Cell-cycle regulation via phosphorylation of RB protein by cyclin-dependent kinase]
-
Kitagawa, M., Taya, Y. [Cell-cycle regulation via phosphorylation of RB protein by cyclin-dependent kinase]. Tanpakushitsu Kakusan Koso 1997, 42(10 Suppl): 1594-602.
-
(1997)
Tanpakushitsu Kakusan Koso
, vol.42
, Issue.10 SUPPL.
, pp. 1594-1602
-
-
Kitagawa, M.1
Taya, Y.2
-
17
-
-
0031016121
-
RB kinases and RB-binding proteins: New points of view
-
Taya Y. RB kinases and RB-binding proteins: new points of view. Trends Biochem Sci 1997, 22(1): 14-7.
-
(1997)
Trends Biochem Sci
, vol.22
, Issue.1
, pp. 14-17
-
-
Taya, Y.1
-
18
-
-
0036901897
-
Loss of Rb overrides the requirement for ERK activity for cell proliferation
-
D'Abaco, G.M., Hooper, S., Paterson, H. and Marshall, C.J. Loss of Rb overrides the requirement for ERK activity for cell proliferation. J Cell Sci 2002, 115(Pt 23): 4607-16.
-
(2002)
J Cell Sci
, vol.115
, Issue.PART 23
, pp. 4607-4616
-
-
D'Abaco, G.M.1
Hooper, S.2
Paterson, H.3
Marshall, C.J.4
-
19
-
-
2642536973
-
Mitogen-induced rapid phosphorylation of serine 795 of the retinoblastoma gene product in vascular smooth muscle cells involves ERK activation
-
Garnovskaya, M.N., Mukhin, Y.V., Vlasova, T.M., Grewal, J.S., Ullian, M.E., Tholanikunnel, B.G. and Raymond, J.R. Mitogen-induced rapid phosphorylation of serine 795 of the retinoblastoma gene product in vascular smooth muscle cells involves ERK activation. J Biol Chem 2004, 279(23): 24899-905.
-
(2004)
J Biol Chem
, vol.279
, Issue.23
, pp. 24899-24905
-
-
Garnovskaya, M.N.1
Mukhin, Y.V.2
Vlasova, T.M.3
Grewal, J.S.4
Ullian, M.E.5
Tholanikunnel, B.G.6
Raymond, J.R.7
-
20
-
-
0031127304
-
Cell cycle: Routine role for Ras
-
Downward J. Cell cycle: routine role for Ras. Curr Biol 1997, 7(4): R258-60.
-
(1997)
Curr Biol
, vol.7
, Issue.4
-
-
Downward, J.1
-
21
-
-
6344245673
-
Disruption of the Rb-Raf-1 interaction inhibits tumor growth and angiogenesis
-
Dasgupta, P., Sun, J., Wang, S. et al. Disruption of the Rb-Raf-1 interaction inhibits tumor growth and angiogenesis. Mol Cell Biol 2004, 24(21): 9527-41.
-
(2004)
Mol Cell Biol
, vol.24
, Issue.21
, pp. 9527-9541
-
-
Dasgupta, P.1
Sun, J.2
Wang, S.3
-
22
-
-
0038124364
-
Targeted delivery of mutant Raf kincise to neovessels causes tumor regression
-
Hood, J.D. and Cheresh, D.A. Targeted delivery of mutant Raf kincise to neovessels causes tumor regression. Cold Spring Harb Symp Quant Biol 2002, 67: 285-91.
-
(2002)
Cold Spring Harb Symp Quant Biol
, vol.67
, pp. 285-291
-
-
Hood, J.D.1
Cheresh, D.A.2
-
23
-
-
33750681312
-
The ABCs of targeting Raf: Novel approaches to cancer therapy
-
Kinkade, R., Dasgupta, P. and Chellappan, S. The ABCs of targeting Raf: Novel approaches to cancer therapy. Curr Cancer Ther Rev 2006, 2(4): 305-14.
-
(2006)
Curr Cancer Ther Rev
, vol.2
, Issue.4
, pp. 305-314
-
-
Kinkade, R.1
Dasgupta, P.2
Chellappan, S.3
-
24
-
-
33749238553
-
Discovery and development of sorafenib: A multikinase inhibitor for treating cancer
-
Wilhelm, S., Carter, C., Lynch, M. et al. Discovery and development of sorafenib: a multikinase inhibitor for treating cancer. Nat Rev Drug Discov 2006 5(10): 835-44.
-
(2006)
Nat Rev Drug Discov
, vol.5
, Issue.10
, pp. 835-844
-
-
Wilhelm, S.1
Carter, C.2
Lynch, M.3
-
25
-
-
4944249117
-
BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis
-
Wilhelm, S.M., Carter, C., Tang, L. et al. BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis. Cancer Res 2004, 64(19): 7099-109.
-
(2004)
Cancer Res
, vol.64
, Issue.19
, pp. 7099-7109
-
-
Wilhelm, S.M.1
Carter, C.2
Tang, L.3
-
26
-
-
0032054248
-
Therapeutic intervention and signaling
-
Heimbrook, D.C. and Oliff, A. Therapeutic intervention and signaling. Curr Opin Cell Biol 1998, 10(2): 284-8.
-
(1998)
Curr Opin Cell Biol
, vol.10
, Issue.2
, pp. 284-288
-
-
Heimbrook, D.C.1
Oliff, A.2
-
27
-
-
34247612847
-
Targeting cell cycle kinases for cancer therapy
-
de Cárcer, G., de Castro, I.P. and Malumbres, M. Targeting cell cycle kinases for cancer therapy. Curr Med Chem 2007, 14(9): 969-85.
-
(2007)
Curr Med Chem
, vol.14
, Issue.9
, pp. 969-985
-
-
de Cárcer, G.1
de Castro, I.P.2
Malumbres, M.3
-
28
-
-
37549036250
-
CDK inhibitors in cancer therapy: What is next?
-
Malumbres, M., Pevarello, P., Barbacid, M. and Bischoff, J.R. CDK inhibitors in cancer therapy: what is next? Trends Pharmacol Sci 2008, 29(1): 16-21.
-
(2008)
Trends Pharmacol Sci
, vol.29
, Issue.1
, pp. 16-21
-
-
Malumbres, M.1
Pevarello, P.2
Barbacid, M.3
Bischoff, J.R.4
-
29
-
-
0142116249
-
Cdk2 knockout mice are viable
-
Berthet, C., Aleem, E., Coppola, V., Tessarollo, L. and Kaldis, P. Cdk2 knockout mice are viable. Curr Biol 2003, 13(20): 1775-85.
-
(2003)
Curr Biol
, vol.13
, Issue.20
, pp. 1775-1785
-
-
Berthet, C.1
Aleem, E.2
Coppola, V.3
Tessarollo, L.4
Kaldis, P.5
-
30
-
-
4444247138
-
Mammalian cells cycle without the D-type cyclin-dependent kinases Cdk4 and Cdk6
-
Malumbres, M., Sotillo, R., Santamaría, D. et al. Mammalian cells cycle without the D-type cyclin-dependent kinases Cdk4 and Cdk6. Cell 2004, 118(4): 493-504.
-
(2004)
Cell
, vol.118
, Issue.4
, pp. 493-504
-
-
Malumbres, M.1
Sotillo, R.2
Santamaría, D.3
-
31
-
-
45549105690
-
A small molecule disruptor of Rb/Raf-1 interaction inhibits cell proliferation, angiogenesis, and growth of human tumor xenografts in nude mice
-
Kinkade, R., Dasgupta, P., Carie, A. et al. A small molecule disruptor of Rb/Raf-1 interaction inhibits cell proliferation, angiogenesis, and growth of human tumor xenografts in nude mice. Cancer Res 2008, 68(10): 3810-8.
-
(2008)
Cancer Res
, vol.68
, Issue.10
, pp. 3810-3818
-
-
Kinkade, R.1
Dasgupta, P.2
Carie, A.3
|