Increase in quantitative variation after exposure to environmental stresses and/or introduction of a major mutation: G x E interaction and epistasis or canalization?

Genetics

Volumn 180, Issue 1, 2008, Pages 687-695

  Zhang, Xu Sheng ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; ENVIRONMENTAL CHANGE; ENVIRONMENTAL EXPOSURE; ENVIRONMENTAL STRESS; EPISTASIS; FITNESS; GENE INTERACTION; GENE MUTATION; GENETIC VARIABILITY; GENOTYPE ENVIRONMENT INTERACTION; INDUCED MUTATION; PHENOTYPIC VARIATION; PLEIOTROPY; PRIORITY JOURNAL; QUANTITATIVE GENETICS; ALLELE; ANIMAL; BIOLOGICAL MODEL; ENVIRONMENT; GENETIC EPISTASIS; GENETIC SELECTION; GENOTYPE; HUMAN; MUTATION; NUCLEOTIDE SEQUENCE; POPULATION DENSITY; POPULATION GENETICS; QUANTITATIVE TRAIT LOCUS; STATISTICAL MODEL;

ALLELES; ANIMALS; DNA MUTATIONAL ANALYSIS; ENVIRONMENT; EPISTASIS, GENETIC; GENETICS, POPULATION; GENOTYPE; HUMANS; MODELS, GENETIC; MODELS, STATISTICAL; MUTATION; POPULATION DENSITY; QUANTITATIVE TRAIT LOCI; SELECTION (GENETICS); VARIATION (GENETICS);

EID: 56049126656     PISSN: 00166731     EISSN: 00166731     Source Type: Journal    
DOI: 10.1534/genetics.108.091611     Document Type: Article

References (41)

1. ALBERT, A. Y. K., S. SAWAY, T. H. VINES, A. K. KNECHT, C. T. MILLER et al., 2008 The genetics of adaptive shape shift in stickleback: pleiotropy and effect size. Evolution 762: 76-85.
2. BAER, C. F., 2008 Quantifying the de-canalizing effects of spontaneous mutations in rhabditid nematodes. Am. Nat. 172: 272-281.
3. BARTON, N. H., and P. D. KEIGHTLEY, 2002 Understanding quantitative genetic variation. Nat. Genet. 3: 11-21.
4. BARTON, N. H., and M. TURELLI, 1989 Evolutionary quantitative genetics: How little do we know? Annu. Rev. Genet. 23: 337-370.
5. CABALLERO, A., and P. D. KEIGHTLEY, 1994 A pleiotropic nonadditive model of variation in quantitative traits. Genetics 138: 883-900.
6. CHARLESWORTH, B., M. T. MORGAN and D. CHARLESWORTH, 1993 The effect of deleterious mutations on neutral molecular variation. Genetics 134: 1289-1303.
7. COOPER, T. F., E. A. OSTROWSKI and M. TRAVISANO, 2007 A negative relationship between mutation pleiotropy and fitness effect in yeast. Evolution 61: 1495-1499.
8. DE VISSER, J. A. G., J. HERMISSON, G. P. WAGNER, L. ANCEL MEYERS, H. BAGHERI- CHAICHIAN et al., 2003 Perspective: evolution and detection of genetic robustness. Evolution 57: 1959-1972.
9. GARCIA-DORADO, A., C. LOPEZ-FANJUL and A. CABALLERO, 1999 Properties of spontaneous mutations affecting quantitative traits. Genet. Res. 74: 341-350.
10. GAVRILETS, S., and A. HASTINGS, 1994 A quantitative-genetic model for selection on development noise. Evolution 48: 1478-1486.
11. GIBSON, G., and I. DWORKIN, 2004 Uncovering cryptic genetic variation. Nat. Rev. Genet. 5: 681-690.
12. GIBSON, G., and S. VAN HELDEN, 1997 Is function of the Drosophila homeotic gene Ultrabithorax canalized? Genetics 147: 1155-1168.
13. EYRE-WALKER, A., and P. D. KEIGHTLEY, 2007 The distribution of fitness effects of new mutations. Nat. Rev. Genet. 8: 610-618.
14. FALCONER, D. S., and T. F. C. MACKAY, 1996 Introduction to Quantitative Genetics, Ed. 4. Longman, Harlow, UK.
15. HANSEN, T. F., 2006 The evolution of genetic architecture. Annu. Rev. Ecol. Syst. 37: 123-157.
16. HERMISSON, J., and G. WAGNER, 2004 The population genetic theory of hidden variation and genetic robustness. Genetics 168: 2271-2284.
17. KEIGHTLEY, P. D., and W. G. HILL, 1990 Variation maintained in quantitative traits with mutation-selection balance: pleiotropic side-effects on fitness traits. Proc. R. Soc. Lond. Ser. B 242: 95-100.
18. KENNEY-HUNT, J. P., B. WANG, E. A. NORGARD, G. FAWCETT, D. FALK et al., 2008 Pleiotropic patterns of quantitative trait loci for 70 murine skeletal traits. Genetics 178: 2275-2288.
19. KIMURA, M., 1965 A stochastic model concerning the maintenance of genetic variability in quantitative characters. Proc. Natl. Acad. Sci. USA 54: 731-736.
20. KIMURA, M., 1969 The number of heterozygous nucleotide sites maintained in a finite population due to steady flux of mutations. Genetics 61: 893-903.
21. LYMAN, R. F., F. LAWRENCE, S. V. NUZHDIN and T. F. C. MACKAY, 1996 Effects of single P-element insertions on bristle number and viability in Drosophila melanogaster. Genetics 143: 277-293.
22. LYNCH, M., and W. G. HILL, 1986 Phenotypic evolution by neutral mutation. Evolution 40: 915-935.
23. LYNCH, M., and B. WALSH, 1998 Genetics and Analysis of Quantitative Traits. Sinauer, Sunderland, MA.
24. LYNCH, M., J. BLANCHARD, D. HOULE, T. KIBOTA, S. SCHULTZ et al., 1999 Perspective: spontaneous deleterious mutation. Evolution 53: 645-663.
25. MACKAY, T. F. C., 2004 The genetic architecture of quantitative trait - lessons from Drosophila. Curr. Opin. Genet. Dev. 14: 253-257.
26. MACKAY, T. F. C., and R. F. LYMAN, 2005 Drosophila bristles and the nature of quantitative genetic variation. Philos. Trans. R. Soc. B Biol. Sci. 360: 1513-1527.
27. MACKAY, T. F. C., R. F. LYMAN and M. S. JACKSON, 1992 Effects of Pelement insertions on quantitative traits in Drosophila melanogaster. Genetics 130: 315-332.
28. MULDER, H. A., P. BIJMA and W. G. HILL, 2007 Prediction of breeding values and selection responses with genetic heterogeneity of environmental variance. Genetics 175: 1895-1910.
29. OSTROWSKI, E. A., D. E. ROZEN and R. E. LENSKI, 2005 Pleiotropic effects of beneficial mutations in Escherichia coli. Evolution 59: 2343-2352.
30. RENDEL, J. M., 1967 Canalization and Gene Control. Logos Press, New York.
31. SCHARLOO, W., 1991 Canalization: genetic and developmental aspects. Annu. Rev. Ecol. Syst. 22: 65-93.
32. TANAKA, Y., 1996 The genetic variance maintained by pleiotropic mutation. Theor. Popul. Biol. 49: 211-231.
33. TURELLI, M., 1984 Heritable genetic variation via mutation-selection balance: Lerch's zeta meets the abdominal bristle. Theo. Popul. Biol. 25: 138-193.
34. WADDINGTON, C. H., 1957 The Strategy of the Genes. Macmillan, New York.
35. WAGNER, P. G., J. P. KENNEY-HUNT, M. PAVLICEV, J. R. PECK, D. WAXMAN et al., 2008 Pleiotropic scaling of gene effects and the 'cost of complexity'. Nature 452: 470-473.
36. WEBER, K. E., and L. T. DIGGINS, 1990 Increased selection response quantitative in large populations. II. Selection for ethanol vapor resistance in Drosophila melanogaster at two population sizes. Genetics 125: 585-597.
37. WHITLOCK, M. C., and K. FOWLER, 1999 The changes in genetic and environmental variance with inbreeding in Drosophila melanogaster. Genetics 152: 345-353.
38. ZHANG, X.-S., and W. G. HILL, 2002 Joint effect of pleiotropic selection and real stabilizing selection on the maintenance of quantitative genetic variation at mutation-selection balance. Genetics 162: 459-471.
39. ZHANG, X.-S., and W. G. HILL, 2005 Evolution of the environmental component of the phenotypic variance: stabilizing selection in changing environments and the homogeneity cost. Evolution 59: 1237-1244.
40. ZHANG, X.-S., and W. G. HILL, 2008 Mutation-selection balance for environmental variance. Am. Nat. 171: 394-399.
41. ZHANG, X.-S., J. WANG and W. G. HILL, 2004 Influence of dominance, leptokurtosis and pleiotropy of deleterious mutations on quantitative genetic variance at mutation-selection balance. Genetics 166: 597-610.