Increased ErbB-2 tyrosine kinase activity, MAPK phosphorylation, and cell proliferation in the prostate cancer cell line LNCaP following treatment by select pesticides

Toxicological Sciences

Volumn 60, Issue 1, 2001, Pages 38-43

  Tessier, Daniel M ^a,b   Matsumura, Fumio ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

ErbB 2 neu HER 2; LNCaP; Mitogen activated protein kinase (MAPK); Pesticides; Prostate cancer; Tyrosine kinases

Indexed keywords

1,1,1 TRICHLORO 2 (2 CHLOROPHENYL) 2 (4 CHLOROPHENYL)ETHANE; ANDROGEN; ANDROGEN RECEPTOR; BETA HEXACHLOROCYCLOHEXANE; CHLOROTHALONIL; FUNGICIDE; HEPTACHLOR EPOXIDE; MITOGEN ACTIVATED PROTEIN KINASE; ORGANOCHLORINE INSECTICIDE; PERMETHRIN; PESTICIDE; PROTEIN TYROSINE KINASE; PYRETHROID; TYROSINE KINASE RECEPTOR;

ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CELL PROLIFERATION; CELL TYPE; COLON CANCER; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; GENE AMPLIFICATION; GENE OVEREXPRESSION; HORMONAL CARCINOGENESIS; HUMAN; HUMAN CELL; MITOSIS; ONCOGENE NEU; PROGNOSIS; PROSTATE CANCER; SIGNAL TRANSDUCTION;

ADENOCARCINOMA; ANDROGEN ANTAGONISTS; CELL DIVISION; DICHLORODIPHENYL DICHLOROETHYLENE; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; INSECTICIDES; MALE; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; PROSTATIC NEOPLASMS; RECEPTOR, ERBB-2; TUMOR CELLS, CULTURED;

EID: 0035091395     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1093/toxsci/60.1.38     Document Type: Article

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