Dopamine D5 receptors: A challenge to medicinal chemists

Mini-Reviews in Medicinal Chemistry

Volumn 8, Issue 10, 2008, Pages 976-995

  Giorgioni, Gian ^a   Piergentili, A ^a   Ruggieri, S ^a   Quaglia, W ^a  

^a UNIVERSITY OF CAMERINO   (Italy)

Author keywords

D1 subtype; D5 subtype; Dopamine receptor ligands; Pharmacophore; Structure activity relationship (SAR)

Indexed keywords

1 AMINOMETHYL 5,6 DIHYDROXY 3 PHENYLISOCHROMAN; 2 DIMETHYLAMINO 6,7 DIHYDROXYTETRALIN; 2,3,4,5 TETRAHYDRO 7,8 DIHYDROXY 1 PHENYL 1H 3 BENZAZEPINE; 4,5,5A,6,7,11B HEXAHYDRO 9,10 DIHYDROXY 2 PROPYL 3 THIA 5 AZACYCLOPENT 1 ENA[C]PHENANTHRENE; 4,6,6A,7,8,12B HEXAHYDRO 7 METHYLINDOLO[4,3 AB]PHENANTHRIDINE; 8 CHLORO 2,3,4,5 TETRAHYDRO 3 METHYL 5 PHENYL 1H 3 BENZAZEPIN 7 OL HYDROGEN MALEATE; A 69930; APOMORPHINE; BENZAZEPINE DERIVATIVE; BROMOCRIPTINE; CABERGOLINE; CHLORPROMAZINE; CLOZAPINE; DIHYDREXIDINE; DOPAMINE 5 RECEPTOR; DOPAMINE RECEPTOR BLOCKING AGENT; DOPAMINE RECEPTOR STIMULATING AGENT; ECOPIPAM; FLUPENTIXOL; FLUPHENAZINE; HALOPERIDOL; ISOCHROMAN DERIVATIVE; ISOQUINOLINE DERIVATIVE; KETANSERIN; LISURIDE; NORADRENALIN; PERGOLIDE; SPIPERONE; SULPIRIDE; THIORIDAZINE; UNCLASSIFIED DRUG; UNINDEXED DRUG; LIGAND;

BINDING AFFINITY; BINDING COMPETITION; CHEMICAL MODIFICATION; DRUG BINDING SITE; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG TARGETING; HUMAN; LIGAND BINDING; NONHUMAN; PHARMACOPHORE; RECEPTOR AFFINITY; REVIEW; STRUCTURE ACTIVITY RELATION; ANIMAL; CELL STRAIN COS1; CERCOPITHECUS; DOSE RESPONSE; DRUG ANTAGONISM; DRUG DESIGN; DRUG POTENTIATION;

(R)-2,3,4,5-TETRAHYDRO-8-CHLORO-3-METHYL-5-PHENYL-1H-3-BENZAZEPIN-7-OL; ANIMALS; APOMORPHINE; CERCOPITHECUS AETHIOPS; COS CELLS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DESIGN; HUMANS; LIGANDS; RECEPTORS, DOPAMINE D5; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 56049118478     PISSN: 13895575     EISSN: None     Source Type: Journal    
DOI: 10.2174/138955708785740661     Document Type: Review

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