Homologous desensitization of the D1(A) dopamine receptor: Efficacy in causing desensitization dissociates from both receptor occupancy and functional potency

Journal of Pharmacology and Experimental Therapeutics

Volumn 286, Issue 1, 1998, Pages 345-353

  Lewis, Mechelle M ^a   Watts, Val J ^a,c   Lawler, Cindy P ^a   Nichols, David E ^b   Mailman, Richard B ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b PURDUE UNIVERSITY   (United States)

^c OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 AMINOMETHYL 5,6 DIHYDROXY 3 PHENYLISOCHROMAN; 2,3,4,5 TETRAHYDRO 7,8 DIHYDROXY 1 PHENYL 1H 3 BENZAZEPINE; 3 (1 ADAMANTYL) 1 AMINOMETHYL 3,4 DIHYDRO 5,6 DIHYDROXY 1H 2 BENZOPYRAN; 3 ALLYL 6 CHLORO 2,3,4,5 TETRAHYDRO 7,8 DIHYDROXY 1 PHENYL 1H 3 BENZAZEPINE; 8 CHLORO 2,3,4,5 TETRAHYDRO 3 METHYL 5 PHENYL 1H 3 BENZAZEPIN 7 OL HYDROGEN MALEATE; DIHYDREXIDINE; DOPAMINE 1 RECEPTOR; DOPAMINE 1 RECEPTOR BLOCKING AGENT; DOPAMINE 1 RECEPTOR STIMULATING AGENT; PERGOLIDE; RECEPTOR SUBTYPE; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; DOPAMINE; DOPAMINE D1A RECEPTOR; DOPAMINE RECEPTOR STIMULATING AGENT;

ANIMAL CELL; ARTICLE; DESENSITIZATION; DRUG EFFICACY; DRUG POTENCY; MONKEY; NONHUMAN; PRIORITY JOURNAL; RECEPTOR BINDING; RECEPTOR DENSITY; ADDICTION; ANIMAL; BIOSYNTHESIS; DOSE RESPONSE; MACACA; METABOLISM; PHYSIOLOGY;

(R)-2,3,4,5-TETRAHYDRO-8-CHLORO-3-METHYL-5-PHENYL-1H-3-BENZAZEPIN-7-OL; ANIMALS; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DOPAMINE; DOPAMINE AGONISTS; DOSE-RESPONSE RELATIONSHIP, DRUG; MACACA MULATTA; RECEPTORS, DOPAMINE D1; SUBSTANCE-RELATED DISORDERS;

EID: 0031597626     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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