Pregnancy-upregulated nonubiquitous calmodulin kinase induces ligand-independent EGFR degradation

American Journal of Physiology - Cell Physiology

Volumn 295, Issue 2, 2008, Pages

  Deb, Tushar B ^a   Coticchia, Christine M ^a   Barndt, Robert ^a   Zuo, Hong ^a   Dickson, Robert B ^a   Johnson, Michael D ^a  

^a GEORGETOWN UNIVERSITY   (United States)

Author keywords

Epidermal growth factor receptor

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; ISOENZYME; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; PREGNANCY UPREGULATED NONUBIQUITOUS CALMODULIN KINASE; PROTEIN KINASE (CALCIUM,CALMODULIN); PROTEIN KINASE (CALCIUM,CALMODULIN) I; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; 4 (3 CHLOROANILINO) 6,7 DIMETHOXYQUINAZOLINE; BAFILOMYCIN A1; BENZYLOXYCARBONYLLEUCYL LEUCYL LEUCINE ALDEHYDE; BENZYLOXYCARBONYLLEUCYL-LEUCYL-LEUCINE ALDEHYDE; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE I; EPIDERMAL GROWTH FACTOR; HYBRID PROTEIN; LEUPEPTIN; LIGAND; MACROLIDE; PHOSPHOPROTEIN; PNCK PROTEIN, HUMAN; PROTEASOME; PROTEIN KINASE INHIBITOR; PROTEINASE INHIBITOR; SIGNAL PEPTIDE; SIGNAL TRANSDUCING ADAPTOR PROTEIN; SRC HOMOLOGY 2 DOMAIN CONTAINING, TRANSFORMING PROTEIN 1; SRC HOMOLOGY 2 DOMAIN-CONTAINING, TRANSFORMING PROTEIN 1; TYRPHOSTIN;

ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CARCINOGENESIS; CELL STRAIN HEK293; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; PREGNANCY; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; UPREGULATION; CELL LINE; DRUG ANTAGONISM; DRUG EFFECT; EPITHELIUM CELL; GENE EXPRESSION; GENETIC TRANSFECTION; GENETICS; LYSOSOME; METABOLISM; PHOSPHORYLATION;

PROTEA;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 1; CELL LINE; DOWN-REGULATION; EPIDERMAL GROWTH FACTOR; EPITHELIAL CELLS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENE EXPRESSION; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LEUPEPTINS; LIGANDS; LYSOSOMES; MACROLIDES; PHOSPHOPROTEINS; PHOSPHORYLATION; PROTEASE INHIBITORS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN KINASE INHIBITORS; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECOMBINANT FUSION PROTEINS; RNA, SMALL INTERFERING; TRANSFECTION; TYRPHOSTINS;

EID: 55949104434     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00449.2007     Document Type: Article

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