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Volumn 194, Issue 4, 2008, Pages 283-291

Control of lipid oxidation during exercise: Role of energy state and mitochondrial factors

Author keywords

Carnitine; Lipid oxidation; Metabolic control; Mitochondria

Indexed keywords

ACYL COENZYME A; ADENOSINE TRIPHOSPHATE; CARBOHYDRATE; CARNITINE; CARNITINE PALMITOYLTRANSFERASE; COENZYME A; GLYCOGEN; LONG CHAIN FATTY ACID; OXYGEN;

EID: 55949097881     PISSN: 17481708     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1748-1716.2008.01879.x     Document Type: Review
Times cited : (24)

References (47)
  • 2
    • 0036142841 scopus 로고    scopus 로고
    • Determination of the exercise intensity that elicits maximal fat oxidation
    • Achten, J., Gleeson, M. Jeukendrup, A.E. 2002. Determination of the exercise intensity that elicits maximal fat oxidation. Med Sci Sports Exerc 34, 92 97.
    • (2002) Med Sci Sports Exerc , vol.34 , pp. 92-97
    • Achten, J.1    Gleeson, M.2    Jeukendrup, A.E.3
  • 3
    • 0014353859 scopus 로고
    • The energy charge of the adenylate pool as a regulatory parameter. Interaction with feedback modifiers
    • Atkinson, D.E. 1968. The energy charge of the adenylate pool as a regulatory parameter. Interaction with feedback modifiers. Biochemistry 7, 4030 4034.
    • (1968) Biochemistry , vol.7 , pp. 4030-4034
    • Atkinson, D.E.1
  • 4
    • 34447533581 scopus 로고    scopus 로고
    • Is membrane transport of FFA mediated by lipid, protein, or both? Mechanisms and regulation of protein-mediated cellular fatty acid uptake: Molecular, biochemical, and physiological evidence
    • Bonen, A., Chabowski, A., Luiken, J.J. Glatz, J.F. 2007. Is membrane transport of FFA mediated by lipid, protein, or both? Mechanisms and regulation of protein-mediated cellular fatty acid uptake: molecular, biochemical, and physiological evidence. Physiology (Bethesda) 22, 15 29.
    • (2007) Physiology (Bethesda) , vol.22 , pp. 15-29
    • Bonen, A.1    Chabowski, A.2    Luiken, J.J.3    Glatz, J.F.4
  • 5
    • 34047223522 scopus 로고    scopus 로고
    • Overexpression of carnitine palmitoyltransferase I in skeletal muscle in vivo increases fatty acid oxidation and reduces triacylglycerol esterification
    • Bruce, C.R., Brolin, C., Turner, N., Cleasby, M.E., van der Leij, F.R., Cooney, G.J. Kraegen, E.W. 2007. Overexpression of carnitine palmitoyltransferase I in skeletal muscle in vivo increases fatty acid oxidation and reduces triacylglycerol esterification. Am J Physiol Endocrinol Metab 292, E1231 E1237.
    • (2007) Am J Physiol Endocrinol Metab , vol.292
    • Bruce, C.R.1    Brolin, C.2    Turner, N.3    Cleasby, M.E.4    Van Der Leij, F.R.5    Cooney, G.J.6    Kraegen, E.W.7
  • 6
    • 4344595619 scopus 로고    scopus 로고
    • A novel function for fatty acid translocase (FAT)/CD36: Involvement in long chain fatty acid transfer into the mitochondria
    • Campbell, S.E., Tandon, N.N., Woldegiorgis, G., Luiken, J.J., Glatz, J.F. Bonen, A. 2004. A novel function for fatty acid translocase (FAT)/CD36: involvement in long chain fatty acid transfer into the mitochondria. J Biol Chem 279, 36235 36241.
    • (2004) J Biol Chem , vol.279 , pp. 36235-36241
    • Campbell, S.E.1    Tandon, N.N.2    Woldegiorgis, G.3    Luiken, J.J.4    Glatz, J.F.5    Bonen, A.6
  • 7
    • 84950387286 scopus 로고
    • Arbeitsfahigkeit und ernahrung. IV. Hypoglykemie, Arbeitsfahigkeit und Ermudung
    • Christensen, E.H. Hansen, O. 1939. Arbeitsfahigkeit und ernahrung. IV. Hypoglykemie, Arbeitsfahigkeit und Ermudung. Scand Archs Physiol 81, 160 181.
    • (1939) Scand Archs Physiol , vol.81 , pp. 160-181
    • Christensen, E.H.1    Hansen, O.2
  • 9
    • 0025836738 scopus 로고
    • Acetyl group accumulation and pyruvate dehydrogenase activity in human muscle during incremental exercise
    • Constantin-Teodosiu, D., Carlin, J.I., Cederblad, G., Harris, R.C. Hultman, E. 1991. Acetyl group accumulation and pyruvate dehydrogenase activity in human muscle during incremental exercise. Acta Physiol Scand 143, 367 372.
    • (1991) Acta Physiol Scand , vol.143 , pp. 367-372
    • Constantin-Teodosiu, D.1    Carlin, J.I.2    Cederblad, G.3    Harris, R.C.4    Hultman, E.5
  • 11
    • 0021891072 scopus 로고
    • Differences in metabolic potential of skeletal muscle fibres and their significance for metabolic control
    • Gollnick, P.D., Riedy, M., Quintinskie, J.J. Bertocci, L.A. 1985. Differences in metabolic potential of skeletal muscle fibres and their significance for metabolic control. J Exp Biol 115, 191 199.
    • (1985) J Exp Biol , vol.115 , pp. 191-199
    • Gollnick, P.D.1    Riedy, M.2    Quintinskie, J.J.3    Bertocci, L.A.4
  • 12
    • 0016888730 scopus 로고
    • Fatty acid activation: Specificity, localization, and function
    • In: R. Paoletti. D. Kritchevsky (. eds). pp. Academic Press, New York.
    • Groot, P., Scholte, H. Hulsmann, W. 1976. Fatty acid activation: specificity, localization, and function. In : R. Paoletti D. Kritchevsky (eds) Advances in Lipid Research, pp. 74 126. Academic Press, New York.
    • (1976) Advances in Lipid Research , pp. 74-126
    • Groot, P.1    Scholte, H.2    Hulsmann, W.3
  • 13
    • 0348062846 scopus 로고    scopus 로고
    • AMP-activated protein kinase: A key system mediating metabolic responses to exercise
    • Hardie, D.G. 2004. AMP-activated protein kinase: a key system mediating metabolic responses to exercise. Med Sci Sports Exerc 36, 28 34.
    • (2004) Med Sci Sports Exerc , vol.36 , pp. 28-34
    • Hardie, D.G.1
  • 14
    • 0023218338 scopus 로고
    • Acetylcarnitine formation during intense muscular contraction in humans
    • Harris, R.C., Foster, C.V. Hultman, E. 1987. Acetylcarnitine formation during intense muscular contraction in humans. J Appl Physiol 63, 440 442.
    • (1987) J Appl Physiol , vol.63 , pp. 440-442
    • Harris, R.C.1    Foster, C.V.2    Hultman, E.3
  • 16
    • 0017701734 scopus 로고
    • Training induced adaptation of skeletal muscle and metabolism during submaximal exercise
    • Henriksson, J. 1977. Training induced adaptation of skeletal muscle and metabolism during submaximal exercise. J Physiol 270, 661 675.
    • (1977) J Physiol , vol.270 , pp. 661-675
    • Henriksson, J.1
  • 17
    • 0021343295 scopus 로고
    • Adaptations of skeletal muscle to endurance exercise and their metabolic consequences
    • Holloszy, J.O. Coyle, E.F. 1984. Adaptations of skeletal muscle to endurance exercise and their metabolic consequences. J Appl Physiol 56, 831 838.
    • (1984) J Appl Physiol , vol.56 , pp. 831-838
    • Holloszy, J.O.1    Coyle, E.F.2
  • 18
    • 33645892283 scopus 로고    scopus 로고
    • Mitochondrial long chain fatty acid oxidation, fatty acid translocase/CD36 content and carnitine palmitoyltransferase I activity in human skeletal muscle during aerobic exercise
    • Holloway, G.P., Bezaire, V., Heigenhauser, G.J., Tandon, N.N., Glatz, J.F., Luiken, J.J., Bonen, A. Spriet, L.L. 2006. Mitochondrial long chain fatty acid oxidation, fatty acid translocase/CD36 content and carnitine palmitoyltransferase I activity in human skeletal muscle during aerobic exercise. J Physiol 571, 201 210.
    • (2006) J Physiol , vol.571 , pp. 201-210
    • Holloway, G.P.1    Bezaire, V.2    Heigenhauser, G.J.3    Tandon, N.N.4    Glatz, J.F.5    Luiken, J.J.6    Bonen, A.7    Spriet, L.L.8
  • 19
    • 0036291378 scopus 로고    scopus 로고
    • Regulation of fat metabolism in skeletal muscle
    • Jeukendrup, A.E. 2002. Regulation of fat metabolism in skeletal muscle. Ann N Y Acad Sci 967, 217 235.
    • (2002) Ann N Y Acad Sci , vol.967 , pp. 217-235
    • Jeukendrup, A.E.1
  • 20
    • 0036788293 scopus 로고    scopus 로고
    • Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes
    • Kelley, D.E., He, J., Menshikova, E.V. Ritov, V.B. 2002. Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes. Diabetes 51, 2944 2950.
    • (2002) Diabetes , vol.51 , pp. 2944-2950
    • Kelley, D.E.1    He, J.2    Menshikova, E.V.3    Ritov, V.B.4
  • 21
    • 33644846005 scopus 로고    scopus 로고
    • Skeletal muscle lipid metabolism in exercise and insulin resistance
    • Kiens, B. 2006. Skeletal muscle lipid metabolism in exercise and insulin resistance. Physiol Rev 86, 205 243.
    • (2006) Physiol Rev , vol.86 , pp. 205-243
    • Kiens, B.1
  • 22
    • 0039677490 scopus 로고    scopus 로고
    • Membrane associated fatty acid binding protein (FABPpm) in human skeletal muscle is increased by endurance training
    • Kiens, B., Kristiansen, S., Jensen, P., Richter, E.A. Turcotte, L.P. 1997. Membrane associated fatty acid binding protein (FABPpm) in human skeletal muscle is increased by endurance training. Biochem Biophys Res Commun 231, 463 465.
    • (1997) Biochem Biophys Res Commun , vol.231 , pp. 463-465
    • Kiens, B.1    Kristiansen, S.2    Jensen, P.3    Richter, E.A.4    Turcotte, L.P.5
  • 23
    • 0033036725 scopus 로고    scopus 로고
    • Muscular long-chain fatty acid content during graded exercise in humans
    • Kiens, B., Roemen, T.H. van der Vusse, G.J. 1999. Muscular long-chain fatty acid content during graded exercise in humans. Am J Physiol 276, E352 E357.
    • (1999) Am J Physiol , vol.276
    • Kiens, B.1    Roemen, T.H.2    Van Der Vusse, G.J.3
  • 24
    • 17644394969 scopus 로고    scopus 로고
    • Subsarcolemmal and intermyofibrillar mitochondria play distinct roles in regulating skeletal muscle fatty acid metabolism
    • Koves, T.R., Noland, R.C., Bates, A.L., Henes, S.T., Muoio, D.M. Cortright, R.N. 2005. Subsarcolemmal and intermyofibrillar mitochondria play distinct roles in regulating skeletal muscle fatty acid metabolism. Am J Physiol Cell Physiol 288, C1074 C1082.
    • (2005) Am J Physiol Cell Physiol , vol.288
    • Koves, T.R.1    Noland, R.C.2    Bates, A.L.3    Henes, S.T.4    Muoio, D.M.5    Cortright, R.N.6
  • 26
    • 0020624753 scopus 로고
    • Observations on the affinity for carnitine, and malonyl-CoA sensitivity, of carnitine palmitoyltransferase I in animal and human tissues. Demonstration of the presence of malonyl-CoA in non-hepatic tissues of the rat
    • McGarry, J.D., Mills, S.E., Long, C.S. Foster, D.W. 1983. Observations on the affinity for carnitine, and malonyl-CoA sensitivity, of carnitine palmitoyltransferase I in animal and human tissues. Demonstration of the presence of malonyl-CoA in non-hepatic tissues of the rat. Biochem J 214, 21 28.
    • (1983) Biochem J , vol.214 , pp. 21-28
    • McGarry, J.D.1    Mills, S.E.2    Long, C.S.3    Foster, D.W.4
  • 27
    • 0000129329 scopus 로고    scopus 로고
    • Cellular processes integrating the metabolic response to exercise
    • In: L.B. Rowell. J.T. Shepherd (. eds). pp. Oxford University Press, New York.
    • Meyer, R.A. Foley, J.M. 1996. Cellular processes integrating the metabolic response to exercise. In : L.B. Rowell J.T. Shepherd (eds) Handbook of Physiology, pp. 841 869. Oxford University Press, New York.
    • (1996) Handbook of Physiology , pp. 841-869
    • Meyer, R.A.1    Foley, J.M.2
  • 28
    • 27244455090 scopus 로고    scopus 로고
    • Mitochondrial efficiency in rat skeletal muscle: Influence of respiration rate, substrate and muscle type
    • Mogensen, M. Sahlin, K. 2005. Mitochondrial efficiency in rat skeletal muscle: influence of respiration rate, substrate and muscle type. Acta Physiol Scand 185, 229 236.
    • (2005) Acta Physiol Scand , vol.185 , pp. 229-236
    • Mogensen, M.1    Sahlin, K.2
  • 29
    • 0015158588 scopus 로고
    • Adaptation of muscle to exercise. Increase in levels of palmityl Coa synthetase, carnitine palmityltransferase, and palmityl Coa dehydrogenase, and in the capacity to oxidize fatty acids
    • Mole, P.A., Oscai, L.B. Holloszy, J.O. 1971. Adaptation of muscle to exercise. Increase in levels of palmityl Coa synthetase, carnitine palmityltransferase, and palmityl Coa dehydrogenase, and in the capacity to oxidize fatty acids. J Clin Invest 50, 2323 2330.
    • (1971) J Clin Invest , vol.50 , pp. 2323-2330
    • Mole, P.A.1    Oscai, L.B.2    Holloszy, J.O.3
  • 32
    • 33646270903 scopus 로고    scopus 로고
    • Whole-body fat oxidation determined by graded exercise and indirect calorimetry: A role for muscle oxidative capacity?
    • Nordby, P., Saltin, B. Helge, J.W. 2006. Whole-body fat oxidation determined by graded exercise and indirect calorimetry: a role for muscle oxidative capacity? Scand J Med Sci Sports 16, 209 214.
    • (2006) Scand J Med Sci Sports , vol.16 , pp. 209-214
    • Nordby, P.1    Saltin, B.2    Helge, J.W.3
  • 33
    • 0031833280 scopus 로고    scopus 로고
    • Skeletal muscle malonyl-CoA content at the onset of exercise at varying power outputs in humans
    • Odland, L.M., Howlett, R.A., Heigenhauser, G.J., Hultman, E. Spriet, L.L. 1998. Skeletal muscle malonyl-CoA content at the onset of exercise at varying power outputs in humans. Am J Physiol 274, E1080 E1085.
    • (1998) Am J Physiol , vol.274
    • Odland, L.M.1    Howlett, R.A.2    Heigenhauser, G.J.3    Hultman, E.4    Spriet, L.L.5
  • 34
    • 0033666003 scopus 로고    scopus 로고
    • Effects of high fat provision on muscle PDH activation and malonyl-CoA content in moderate exercise
    • Odland, L.M., Heigenhauser, G.J. Spriet, L.L. 2000. Effects of high fat provision on muscle PDH activation and malonyl-CoA content in moderate exercise. J Appl Physiol 89, 2352 2358.
    • (2000) J Appl Physiol , vol.89 , pp. 2352-2358
    • Odland, L.M.1    Heigenhauser, G.J.2    Spriet, L.L.3
  • 35
    • 0016438089 scopus 로고
    • Regulation of long chain fatty acid activation in heart muscle
    • Oram, J.F., Wenger, J.I. Neely, J.R. 1975. Regulation of long chain fatty acid activation in heart muscle. J Biol Chem 250, 73 78.
    • (1975) J Biol Chem , vol.250 , pp. 73-78
    • Oram, J.F.1    Wenger, J.I.2    Neely, J.R.3
  • 37
    • 0025237802 scopus 로고
    • Muscle carnitine metabolism during incremental dynamic exercise in humans
    • Sahlin, K. 1990. Muscle carnitine metabolism during incremental dynamic exercise in humans. Acta Physiol Scand 138, 259 262.
    • (1990) Acta Physiol Scand , vol.138 , pp. 259-262
    • Sahlin, K.1
  • 38
    • 0024332542 scopus 로고
    • Hypoxaemia increases the accumulation of inosine monophosphate (IMP) in human skeletal muscle during submaximal exercise
    • Sahlin, K. Katz, A. 1989. Hypoxaemia increases the accumulation of inosine monophosphate (IMP) in human skeletal muscle during submaximal exercise. Acta Physiol Scand 136, 199 203.
    • (1989) Acta Physiol Scand , vol.136 , pp. 199-203
    • Sahlin, K.1    Katz, A.2
  • 39
    • 0017042973 scopus 로고
    • Lactate content and pH in muscle obtained after dynamic exercise
    • Sahlin, K., Harris, R.C., Nylind, B. Hultman, E. 1976. Lactate content and pH in muscle obtained after dynamic exercise. Pflugers Arch 367, 143 149.
    • (1976) Pflugers Arch , vol.367 , pp. 143-149
    • Sahlin, K.1    Harris, R.C.2    Nylind, B.3    Hultman, E.4
  • 40
    • 0023278337 scopus 로고
    • Redox state and lactate accumulation in human skeletal muscle during dynamic exercise
    • Sahlin, K., Katz, A. Henriksson, J. 1987. Redox state and lactate accumulation in human skeletal muscle during dynamic exercise. Biochem J 245, 551 556.
    • (1987) Biochem J , vol.245 , pp. 551-556
    • Sahlin, K.1    Katz, A.2    Henriksson, J.3
  • 41
    • 33845972222 scopus 로고    scopus 로고
    • The potential for mitochondrial fat oxidation in human skeletal muscle influences whole body fat oxidation during low-intensity exercise
    • Sahlin, K., Mogensen, M., Bagger, M., Fernstrom, M. Pedersen, P.K. 2007. The potential for mitochondrial fat oxidation in human skeletal muscle influences whole body fat oxidation during low-intensity exercise. Am J Physiol Endocrinol Metab 292, E223 E230.
    • (2007) Am J Physiol Endocrinol Metab , vol.292
    • Sahlin, K.1    Mogensen, M.2    Bagger, M.3    Fernstrom, M.4    Pedersen, P.K.5
  • 42
    • 0030741642 scopus 로고    scopus 로고
    • Regulation of plasma fatty acid oxidation during low- and high-intensity exercise
    • Sidossis, L.S., Gastaldelli, A., Klein, S. Wolfe, R.R. 1997. Regulation of plasma fatty acid oxidation during low- and high-intensity exercise. Am J Physiol 272, E1065 E1070.
    • (1997) Am J Physiol , vol.272
    • Sidossis, L.S.1    Gastaldelli, A.2    Klein, S.3    Wolfe, R.R.4
  • 43
    • 0042661099 scopus 로고    scopus 로고
    • Regulatory mechanisms in the interaction between carbohydrate and lipid oxidation during exercise
    • Spriet, L.L. Watt, M.J. 2003. Regulatory mechanisms in the interaction between carbohydrate and lipid oxidation during exercise. Acta Physiol Scand 178, 443 452.
    • (2003) Acta Physiol Scand , vol.178 , pp. 443-452
    • Spriet, L.L.1    Watt, M.J.2
  • 46
    • 0026773244 scopus 로고
    • Increased plasma FFA uptake and oxidation during prolonged exercise in trained vs. untrained humans
    • Turcotte, L.P., Richter, E.A. Kiens, B. 1992. Increased plasma FFA uptake and oxidation during prolonged exercise in trained vs. untrained humans. Am J Physiol 262, E791 E799.
    • (1992) Am J Physiol , vol.262
    • Turcotte, L.P.1    Richter, E.A.2    Kiens, B.3


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