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Volumn 36, Issue 1, 2004, Pages 28-34

AMP-Activated Protein Kinase: A Key System Mediating Metabolic Responses to Exercise

Author keywords

ATP depletion; Diabetes; Energy sensing; Fatty acid oxidation; Glucose uptake; Metformin

Indexed keywords

ADENOSINE PHOSPHATE; FATTY ACID; GLUCOSE; GLYCOGEN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; PROTEIN KINASE;

EID: 0348062846     PISSN: 01959131     EISSN: None     Source Type: Journal    
DOI: 10.1249/01.MSS.0000106171.38299.64     Document Type: Conference Paper
Times cited : (137)

References (60)
  • 2
    • 0035970805 scopus 로고    scopus 로고
    • Continuous fatty acid oxidation and reduced fat storage in mice lacking acetyl-CoA carboxylase 2
    • ABU-ELHEIGA, L., M. M. MATZUK, K. A. ABO-HASHEMA, and S. J. WAKIL. Continuous fatty acid oxidation and reduced fat storage in mice lacking acetyl-CoA carboxylase 2. Science 291:2613-2616, 2001.
    • (2001) Science , vol.291 , pp. 2613-2616
    • Abu-Elheiga, L.1    Matzuk, M.M.2    Abo-Hashema, K.A.3    Wakil, S.J.4
  • 3
    • 0036084141 scopus 로고    scopus 로고
    • Effect of fiber type and nutritional state on AICAR- and contraction-stimulated glucose transport in rat muscle
    • AI, H., J. IHLEMANN, Y. HELLSTEN, et al. Effect of fiber type and nutritional state on AICAR- and contraction-stimulated glucose transport in rat muscle. Am. J. Physiol. 282:E1291-E1300, 2002.
    • (2002) Am. J. Physiol. , vol.282
    • Ai, H.1    Ihlemann, J.2    Hellsten, Y.3
  • 4
    • 0035029874 scopus 로고    scopus 로고
    • Effect of 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside infusion on in vivo glucose and lipid metabolism in lean and obese Zucker rats
    • BERGERON, R., S. F. PREVIS, G. W. CLINE, et al. Effect of 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside infusion on in vivo glucose and lipid metabolism in lean and obese Zucker rats. Diabetes 50:1076-1082, 2001.
    • (2001) Diabetes , vol.50 , pp. 1076-1082
    • Bergeron, R.1    Previs, S.F.2    Cline, G.W.3
  • 5
    • 0036307179 scopus 로고    scopus 로고
    • Long-term A1CAR administration reduces metabolic disturbances and lowers blood pressure in rats displaying features of the insulin resistance syndrome
    • BUHL, E. S., N. JESSEN, R. POLD, et al. Long-term A1CAR administration reduces metabolic disturbances and lowers blood pressure in rats displaying features of the insulin resistance syndrome. Diabetes 51:2199-2206, 2002.
    • (2002) Diabetes , vol.51 , pp. 2199-2206
    • Buhl, E.S.1    Jessen, N.2    Pold, R.3
  • 6
    • 0035155821 scopus 로고    scopus 로고
    • Chronic treatment with 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside increases insulin-stimulated glucose uptake and GLUT4 translocation in rat skeletal muscles in a fiber type-specific manner
    • BUHL, E. S., N. JESSEN, O. SCHMITZ, et al. Chronic treatment with 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside increases insulin-stimulated glucose uptake and GLUT4 translocation in rat skeletal muscles in a fiber type-specific manner. Diabetes 50:12-17, 2001.
    • (2001) Diabetes , vol.50 , pp. 12-17
    • Buhl, E.S.1    Jessen, N.2    Schmitz, O.3
  • 7
    • 0028310837 scopus 로고
    • Mammalian AMP-activated protein kinase is homologous to yeast and plant protein kinases involved in the regulation of carbon metabolism
    • CARLING, D., K. AGUAN, A. WOODS, et al. Mammalian AMP-activated protein kinase is homologous to yeast and plant protein kinases involved in the regulation of carbon metabolism. J. Biol. Chem. 269:11442-11448, 1994.
    • (1994) J. Biol. Chem. , vol.269 , pp. 11442-11448
    • Carling, D.1    Aguan, K.2    Woods, A.3
  • 8
    • 0024335432 scopus 로고
    • The substrate and sequence specificity of the AMP-activated protein kinase: Phosphorylation of glycogen synthase and phosphorylase kinase
    • CARLING, D., and D. G. HARDIE. The substrate and sequence specificity of the AMP-activated protein kinase: phosphorylation of glycogen synthase and phosphorylase kinase. Biochim. Biophys. Acta 1012:81-86, 1989.
    • (1989) Biochim. Biophys. Acta , vol.1012 , pp. 81-86
    • Carling, D.1    Hardie, D.G.2
  • 9
    • 0023642627 scopus 로고
    • A common bicyclic protein kinase cascade inactivates the regulatory enzymes of fatty acid and cholesterol biosynthesis
    • CARLING, D., V. A. ZAMMIT, and D. G. HARDIE. A common bicyclic protein kinase cascade inactivates the regulatory enzymes of fatty acid and cholesterol biosynthesis. FEBS Lett. 223:217-222, 1987.
    • (1987) FEBS Lett. , vol.223 , pp. 217-222
    • Carling, D.1    Zammit, V.A.2    Hardie, D.G.3
  • 10
    • 0033016641 scopus 로고    scopus 로고
    • Liver AMP-activated protein kinase and acetyl-CoA carboxylase during and after exercise
    • CARLSON, C. L., and W. W. WINDER. Liver AMP-activated protein kinase and acetyl-CoA carboxylase during and after exercise. J. Appl. Physiol. 86:669-674, 1999.
    • (1999) J. Appl. Physiol. , vol.86 , pp. 669-674
    • Carlson, C.L.1    Winder, W.W.2
  • 11
    • 0022534202 scopus 로고
    • A yeast gene that is essential for release from glucose repression encodes a protein kinase
    • CELENZA, J. L., and M. CARLSON. A yeast gene that is essential for release from glucose repression encodes a protein kinase. Science 233:1175-1180, 1986.
    • (1986) Science , vol.233 , pp. 1175-1180
    • Celenza, J.L.1    Carlson, M.2
  • 12
    • 0033667964 scopus 로고    scopus 로고
    • AMPK signaling in contracting human skeletal muscle: Acetyl-CoA carboxylase and NO synthase phosphorylation
    • CHEN, Z. P., G. K. MCCONELL, B. J. MICHELL, R. J. SNOW, B. J. CANNY, and B. E. KEMP. AMPK signaling in contracting human skeletal muscle: acetyl-CoA carboxylase and NO synthase phosphorylation. Am. J. Physiol. 279:E1202-E1206, 2000.
    • (2000) Am. J. Physiol. , vol.279
    • Chen, Z.P.1    Mcconell, G.K.2    Michell, B.J.3    Snow, R.J.4    Canny, B.J.5    Kemp, B.E.6
  • 13
    • 0034654362 scopus 로고    scopus 로고
    • Characterization of AMP-activated protein kinase g sub-unit isoforms and their role in AMP binding
    • CHEUNG, P. C. F., I. P. SALT, S. P. DAVIES, D. G. HARDIE, and D. CARLING. Characterization of AMP-activated protein kinase g sub-unit isoforms and their role in AMP binding. Biochem. J. 346: 659-669, 2000.
    • (2000) Biochem. J. , vol.346 , pp. 659-669
    • Cheung, P.C.F.1    Salt, I.P.2    Davies, S.P.3    Hardie, D.G.4    Carling, D.5
  • 14
    • 85047689953 scopus 로고
    • 5-Aminoimidazole-4-carboxamide ribonucleoside: A specific method for activating AMP-activated protein kinase in intact cells?
    • CORTON, J. M., J. G. GILLESPIE, S. A. HAWLEY, and D. G. HARDIE. 5-Aminoimidazole-4-carboxamide ribonucleoside: a specific method for activating AMP-activated protein kinase in intact cells? Eur. J. Biochem. 229:558-565, 1995.
    • (1995) Eur. J. Biochem. , vol.229 , pp. 558-565
    • Corton, J.M.1    Gillespie, J.G.2    Hawley, S.A.3    Hardie, D.G.4
  • 15
    • 0024839973 scopus 로고
    • Tissue distribution of the AMP-activated protein kinase, and lack of activation by cyclic AMP-dependent protein kinase, studied using a specific and sensitive peptide assay
    • DAVIES, S. P., D. CARLING, and D. G. HARDIE. Tissue distribution of the AMP-activated protein kinase, and lack of activation by cyclic AMP-dependent protein kinase, studied using a specific and sensitive peptide assay. Eur. J. Biochem. 186:123-128, 1989.
    • (1989) Eur. J. Biochem. , vol.186 , pp. 123-128
    • Davies, S.P.1    Carling, D.2    Hardie, D.G.3
  • 16
    • 0028068882 scopus 로고
    • Purification of the AMP-activated protein kinase on ATP-g-Sepharose and analysis of its subunit structure
    • DAVIES, S. P., S. A. HAWLEY, A. WOODS, D. CARLING, T. A. J. HAYSTEAD, and D. G. HARDIE. Purification of the AMP-activated protein kinase on ATP-g-Sepharose and analysis of its subunit structure. Eur. J. Biochem. 223:351-357, 1994.
    • (1994) Eur. J. Biochem. , vol.223 , pp. 351-357
    • Davies, S.P.1    Hawley, S.A.2    Woods, A.3    Carling, D.4    Haystead, T.A.J.5    Hardie, D.G.6
  • 17
    • 0033855904 scopus 로고    scopus 로고
    • Exercise diminishes the activity of acetyl-CoA carboxylase in human muscle
    • DEAN, D., J. R. DAUGAARD, M. E. YOUNG, et al. Exercise diminishes the activity of acetyl-CoA carboxylase in human muscle. Diabetes 49:1295-1300, 2000.
    • (2000) Diabetes , vol.49 , pp. 1295-1300
    • Dean, D.1    Daugaard, J.R.2    Young, M.E.3
  • 18
    • 0036298152 scopus 로고    scopus 로고
    • Effects of endurance training on activity and expression of AMP-activated protein kinase isoforms in rat muscles
    • DURANTE, P. E., K. J. MUSTARD, S. H. PARK, W. W. WINDER, and D. G. HARDIE. Effects of endurance training on activity and expression of AMP-activated protein kinase isoforms in rat muscles. Am. J. Physiol. 283:E178-E186, 2002.
    • (2002) Am. J. Physiol. , vol.283
    • Durante, P.E.1    Mustard, K.J.2    Park, S.H.3    Winder, W.W.4    Hardie, D.G.5
  • 19
    • 0024327694 scopus 로고
    • Synergistic phosphorylation of rabbit muscle glycogen synthase by cyclic AMP-dependent protein kinase and casein kinase I. Implications for hormonal regulation of glycogen synthase
    • FLOTOW, H., and P. J. ROACH. Synergistic phosphorylation of rabbit muscle glycogen synthase by cyclic AMP-dependent protein kinase and casein kinase I. Implications for hormonal regulation of glycogen synthase. J. Biol. Chem. 264:9126-9128, 1989.
    • (1989) J. Biol. Chem. , vol.264 , pp. 9126-9128
    • Flotow, H.1    Roach, P.J.2
  • 20
    • 0000368683 scopus 로고    scopus 로고
    • Exercise induces isoform-specific increase in 5′AMP-activated protein kinase activity in human skeletal muscle
    • FUJII, N., T. HAYASHI, M. F. HIRSHMAN, et al. Exercise induces isoform-specific increase in 5′AMP-activated protein kinase activity in human skeletal muscle. Biochem. Biophys. Res. Commun. 273:1150-1155, 2000.
    • (2000) Biochem. Biophys. Res. Commun. , vol.273 , pp. 1150-1155
    • Fujii, N.1    Hayashi, T.2    Hirshman, M.F.3
  • 21
    • 0035580981 scopus 로고    scopus 로고
    • Malonyl-COA decarboxylase is not a substrate of AMP-activated protein kinase in rat fast-twitch skeletal muscle or an islet cell line
    • HABINOWSKI, S. A., M. HIRSHMAN, K. SAKAMOTO, et al. Malonyl-COA decarboxylase is not a substrate of AMP-activated protein kinase in rat fast-twitch skeletal muscle or an islet cell line. Arch. Biochem. Biophys. 396:71-79, 2001.
    • (2001) Arch. Biochem. Biophys. , vol.396 , pp. 71-79
    • Habinowski, S.A.1    Hirshman, M.2    Sakamoto, K.3
  • 22
    • 0035542970 scopus 로고    scopus 로고
    • AMP-activated protein kinase: The energy charge hypothesis revisited
    • HARDIE, D. G., and S. A. HAWLEY. AMP-activated protein kinase: the energy charge hypothesis revisited. BioEssays 23:1112-1119, 2001.
    • (2001) BioEssays , vol.23 , pp. 1112-1119
    • Hardie, D.G.1    Hawley, S.A.2
  • 23
    • 0033560109 scopus 로고    scopus 로고
    • AMP-activated protein kinase: An ultrasensitive system for monitoring cellular energy charge
    • HARDIE, D. G., I. P. SALT, S. A. HAWLEY, and S. P. DAVIES. AMP-activated protein kinase: an ultrasensitive system for monitoring cellular energy charge. Biochem. J. 338:717-722, 1999.
    • (1999) Biochem. J. , vol.338 , pp. 717-722
    • Hardie, D.G.1    Salt, I.P.2    Hawley, S.A.3    Davies, S.P.4
  • 24
    • 0031849916 scopus 로고    scopus 로고
    • Evidence for 5′ AMP-activated protein kinase mediation of the effect of muscle contraction on glucose transport
    • HAYASHI, T., M. F. HIRSHMAN, E. J. KURTH, W. W. WINDER, and L. J. GOODYEAR. Evidence for 5′ AMP-activated protein kinase mediation of the effect of muscle contraction on glucose transport. Diabetes 47:1369-1373, 1998.
    • (1998) Diabetes , vol.47 , pp. 1369-1373
    • Hayashi, T.1    Hirshman, M.F.2    Kurth, E.J.3    Winder, W.W.4    Goodyear, L.J.5
  • 25
    • 0029005507 scopus 로고
    • Inhibition of fatty acid and cholesterol synthesis by stimulation of AMP-activated protein kinase
    • HENIN, N., M. F. VINCENT, H. E. GRUBER, and G. VAN DEN BERGHE. Inhibition of fatty acid and cholesterol synthesis by stimulation of AMP-activated protein kinase. FASEB J. 9:541-546, 1995.
    • (1995) FASEB J. , vol.9 , pp. 541-546
    • Henin, N.1    Vincent, M.F.2    Gruber, H.E.3    Van Den Berghe, G.4
  • 26
    • 0021343295 scopus 로고
    • Adaptations of skeletal muscle to endurance exercise and their metabolic consequences
    • HOLLOSZY, J. O., and E. F. COYLE. Adaptations of skeletal muscle to endurance exercise and their metabolic consequences. J. Appl. Physiol. 56:831-838, 1984.
    • (1984) J. Appl. Physiol. , vol.56 , pp. 831-838
    • Holloszy, J.O.1    Coyle, E.F.2
  • 27
    • 0032704115 scopus 로고    scopus 로고
    • Chronic activation of 5′-AMP-activated protein kinase increases GLUT-4, hexokinase, and glycogen in muscle
    • HOLMES, B. F., E. J. KURTH-KRACZEK, and W. W. WINDER. Chronic activation of 5′-AMP-activated protein kinase increases GLUT-4, hexokinase, and glycogen in muscle. J. Appl. Physiol. 87:1990-1995, 1999.
    • (1999) J. Appl. Physiol. , vol.87 , pp. 1990-1995
    • Holmes, B.F.1    Kurth-Kraczek, E.J.2    Winder, W.W.3
  • 28
    • 0038814313 scopus 로고    scopus 로고
    • A novel domain in AMP-activated protein kinase causes glycogen storage bodies similar to those seen in hereditary cardiac arrhythmias
    • HUDSON, E. R., D. A. PAN, J. JAMES, et al. A novel domain in AMP-activated protein kinase causes glycogen storage bodies similar to those seen in hereditary cardiac arrhythmias. Curr. Biol. 13:861-866, 2003.
    • (2003) Curr. Biol. , vol.13 , pp. 861-866
    • Hudson, E.R.1    Pan, D.A.2    James, J.3
  • 29
    • 0030901556 scopus 로고    scopus 로고
    • Electrical stimulation inactivates muscle acetyl-CoA carboxylase and increases AMP-activated protein kinase activity
    • HUTBER, C. A., D. G. HARDIE, and W. W. WINDER. Electrical stimulation inactivates muscle acetyl-CoA carboxylase and increases AMP-activated protein kinase activity. Am. J. Physiol. 272:E262-E266, 1997.
    • (1997) Am. J. Physiol. , vol.272
    • Hutber, C.A.1    Hardie, D.G.2    Winder, W.W.3
  • 30
    • 0034675354 scopus 로고    scopus 로고
    • AMP-activated protein kinase is activated by the stimulations of G(q)-coupled receptors
    • KISHI, K., T. YUASA, A. MINAMI, et al. AMP-activated protein kinase is activated by the stimulations of G(q)-coupled receptors. Biochem. Biophys. Res. Commun. 276:16-22, 2000.
    • (2000) Biochem. Biophys. Res. Commun. , vol.276 , pp. 16-22
    • Kishi, K.1    Yuasa, T.2    Minami, A.3
  • 31
    • 0032765396 scopus 로고    scopus 로고
    • 5′ AMP-activated protein kinase activation causes GLUT 4 translocation in skeletal muscle
    • KURTH-KRACZEK, E. J., M. F. HIRSHMAN, L. J. GOODYEAR, and W. W. WINDER. 5′ AMP-activated protein kinase activation causes GLUT4 translocation in skeletal muscle. Diabetes 48:1667-1671, 1999.
    • (1999) Diabetes , vol.48 , pp. 1667-1671
    • Kurth-Kraczek, E.J.1    Hirshman, M.F.2    Goodyear, L.J.3    Winder, W.W.4
  • 32
    • 0035406121 scopus 로고    scopus 로고
    • Hepatocyte nuclear factor-4a involved in type 1 maturity-onset diabetes of the young is a novel target of AMP-activated protein kinase
    • LECLERC, I., C. LENZNER, L. GOURDON, S. VAULONT, A. KAHN, and B. VIOLLET. Hepatocyte nuclear factor-4a involved in type 1 maturity-onset diabetes of the young is a novel target of AMP-activated protein kinase. Diabetes 50:1515-1521, 2001.
    • (2001) Diabetes , vol.50 , pp. 1515-1521
    • Leclerc, I.1    Lenzner, C.2    Gourdon, L.3    Vaulont, S.4    Kahn, A.5    Viollet, B.6
  • 33
    • 0037383091 scopus 로고    scopus 로고
    • 5-Aminoimidazole-4-carboxamide 1-beta-D-ribofuranoside (AICAR) stimulates myocardial glycogenolysis by allosteric mechanisms
    • LONGNUS, S. L., R. B. WAMBOLT, H. L. PARSONS, R. W. BROWNSEY, and M. F. ALLARD. 5-Aminoimidazole-4-carboxamide 1-beta-D-ribofuranoside (AICAR) stimulates myocardial glycogenolysis by allosteric mechanisms. Am. J. Physiol. 284:R936-R944, 2003.
    • (2003) Am. J. Physiol. , vol.284
    • Longnus, S.L.1    Wambolt, R.B.2    Parsons, H.L.3    Brownsey, R.W.4    Allard, M.F.5
  • 34
    • 0031043030 scopus 로고    scopus 로고
    • The mitochondrial carnitine palmitoyltransferase system: From concept to molecular analysis
    • MCGARRY, J. D., and N. F. BROWN. The mitochondrial carnitine palmitoyltransferase system: from concept to molecular analysis. Eur. J. Biochem. 244:1-14, 1997.
    • (1997) Eur. J. Biochem. , vol.244 , pp. 1-14
    • Mcgarry, J.D.1    Brown, N.F.2
  • 36
    • 0031425839 scopus 로고    scopus 로고
    • AICAR decreases malonyl-CoA and increases fatty acid oxidation in skeletal muscle of the rat
    • MERRILL, G. M., E. KURTH, D. G. HARDIE, and W. W. WINDER. AICAR decreases malonyl-CoA and increases fatty acid oxidation in skeletal muscle of the rat. Am. J. Physiol. 273:E1107-E1112, 1997.
    • (1997) Am. J. Physiol. , vol.273
    • Merrill, G.M.1    Kurth, E.2    Hardie, D.G.3    Winder, W.W.4
  • 37
    • 0035947235 scopus 로고    scopus 로고
    • A role for AMP-activated protein kinase in contraction- and hypoxia-regulated glucose transport in skeletal muscle
    • MU, J., J. T. BROZINICK, O. VALLADARES, M. BUCAN, and M. J. BIRNBAUM. A role for AMP-activated protein kinase in contraction- and hypoxia-regulated glucose transport in skeletal muscle. Mol. Cell 7:1085-1094, 2001.
    • (2001) Mol. Cell , vol.7 , pp. 1085-1094
    • Mu, J.1    Brozinick, J.T.2    Valladares, O.3    Bucan, M.4    Birnbaum, M.J.5
  • 38
    • 0037311651 scopus 로고    scopus 로고
    • 5′-AMP-activated protein kinase activity and subunit expression in exercise-trained human skeletal muscle
    • NIELSEN, J. N., K. J. MUSTARD, D. A. GRAHAM, et al. 5′ -AMP-activated protein kinase activity and subunit expression in exercise-trained human skeletal muscle. J. Appl. Physiol. 94:631-641, 2003.
    • (2003) J. Appl. Physiol. , vol.94 , pp. 631-641
    • Nielsen, J.N.1    Mustard, K.J.2    Graham, D.A.3
  • 39
    • 0037096151 scopus 로고    scopus 로고
    • Role of 5′-AMP activated protein kinase in exercise regulation of glucose utilization and glycogen synthase activity in skeletal muscle from patients with McArdle's disease
    • NIELSEN, J. N., J. F. P. WOJTASZEWSKI, R. G. HALLER, et al. Role of 5′-AMP activated protein kinase in exercise regulation of glucose utilization and glycogen synthase activity in skeletal muscle from patients with McArdle's disease. J. Physiol. 541:979-989, 2002.
    • (2002) J. Physiol. , vol.541 , pp. 979-989
    • Nielsen, J.N.1    Wojtaszewski, J.F.P.2    Haller, R.G.3
  • 40
    • 0037031840 scopus 로고    scopus 로고
    • Coordinate regulation of malonyl-CoA decarboxylase, sn-glycerol-3-phosphate acyltransferase, and acetyl-CoA carboxylase by AMP-activated protein kinase in rat tissues in response to exercise
    • PARK, H., V. K. KAUSHIK, S. CONSTANT, et al. Coordinate regulation of malonyl-CoA decarboxylase, sn-glycerol-3-phosphate acyltransferase, and acetyl-CoA carboxylase by AMP-activated protein kinase in rat tissues in response to exercise. J. Biol. Chem. 277:32571-32577, 2002.
    • (2002) J. Biol. Chem. , vol.277 , pp. 32571-32577
    • Park, H.1    Kaushik, V.K.2    Constant, S.3
  • 41
    • 0037799908 scopus 로고    scopus 로고
    • AMPK b-subunit targets metabolic stress-sensing to glycogen
    • POLEKHINA, G., A. GUPTA, B. J. MICHELL, et al. AMPK b-subunit targets metabolic stress-sensing to glycogen. Curr. Biol. 13:867-871, 2003.
    • (2003) Curr. Biol. , vol.13 , pp. 867-871
    • Polekhina, G.1    Gupta, A.2    Michell, B.J.3
  • 42
    • 0032536774 scopus 로고    scopus 로고
    • Dual regulation of the AMP-activated protein kinase provides a novel mechanism for the control of creatine kinase in skeletal muscle
    • PONTICOS, M., Q. L. LU, J. E. MORGAN, D. G. HARDIE, T. A. PARTRIDGE, and D. CARLING. Dual regulation of the AMP-activated protein kinase provides a novel mechanism for the control of creatine kinase in skeletal muscle. EMBO J. 17:1688-1699, 1998.
    • (1998) EMBO J. , vol.17 , pp. 1688-1699
    • Ponticos, M.1    Lu, Q.L.2    Morgan, J.E.3    Hardie, D.G.4    Partridge, T.A.5    Carling, D.6
  • 43
    • 0031769058 scopus 로고    scopus 로고
    • Postexercise recovery of skeletal muscle malonyl-CoA, acetyl-CoA carboxylase, and AMP-activated protein kinase
    • RASMUSSEN, B. B., C. R. HANCOCK, and W. W. WINDER. Postexercise recovery of skeletal muscle malonyl-CoA, acetyl-CoA carboxylase, and AMP-activated protein kinase. J. Appl. Physiol. 85:1629-1634, 1998.
    • (1998) J. Appl. Physiol. , vol.85 , pp. 1629-1634
    • Rasmussen, B.B.1    Hancock, C.R.2    Winder, W.W.3
  • 44
    • 0030863587 scopus 로고    scopus 로고
    • Effect of exercise intensity on skeletal muscle malonyl-CoA and acetyl-CoA carboxylase
    • RASMUSSEN, B. B., and W. W. WINDER. Effect of exercise intensity on skeletal muscle malonyl-CoA and acetyl-CoA carboxylase. J. Appl. Physiol. 83:1104-1109, 1997.
    • (1997) J. Appl. Physiol. , vol.83 , pp. 1104-1109
    • Rasmussen, B.B.1    Winder, W.W.2
  • 45
    • 0035449518 scopus 로고    scopus 로고
    • Glucose exercise and insulin: Emerging concepts
    • RICHTER, E. A., W. DERAVE, and J. F. WOJTASZEWSKI. Glucose, exercise and insulin: emerging concepts. J. Physiol. 535:313-322, 2001.
    • (2001) J. Physiol. , vol.535 , pp. 313-322
    • Richter, E.A.1    Derave, W.2    Wojtaszewski, J.F.3
  • 46
    • 0034637538 scopus 로고    scopus 로고
    • Activation of malonyl-CoA decarboxylase in rat skeletal muscle by contraction and the AMP-activated protein kinase activator 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside
    • SAHA, A. K., A. J. SCHWARSIN, R. RODUIT, et al. Activation of malonyl-CoA decarboxylase in rat skeletal muscle by contraction and the AMP-activated protein kinase activator 5-aminoimidazole-4-carboxamide-1-beta -D-ribofuranoside [In Process Citation]. J. Biol. Chem. 275:24279-24283, 2000.
    • (2000) J. Biol. Chem. , vol.275 , pp. 24279-24283
    • Saha, A.K.1    Schwarsin, A.J.2    Roduit, R.3
  • 47
    • 0023896220 scopus 로고
    • The low activity of acetyl-CoA carboxylase in basal and glucagon-stimulated hepatocytes is due to phosphorylation by the AMP-activated protein kinase and not cyclic AMP-dependent protein kinase
    • SIM, A. T. R., and D. G. HARDIE. The low activity of acetyl-CoA carboxylase in basal and glucagon-stimulated hepatocytes is due to phosphorylation by the AMP-activated protein kinase and not cyclic AMP-dependent protein kinase. FEBS Lett. 233:294-298, 1988.
    • (1988) FEBS Lett. , vol.233 , pp. 294-298
    • Sim, A.T.R.1    Hardie, D.G.2
  • 48
    • 0036088360 scopus 로고    scopus 로고
    • Progressive increase in human skeletal muscle AMPK a2 activity and ACC phosphorylation during exercise
    • STEPHENS, T. J., Z. P. CHEN, B. J. CANNY, B. J. MICHELL, B. E. KEMP, and G. K. MCCONELL. Progressive increase in human skeletal muscle AMPK a2 activity and ACC phosphorylation during exercise. Am. J. Physiol. 282:E688-E694, 2002.
    • (2002) Am. J. Physiol. , vol.282
    • Stephens, T.J.1    Chen, Z.P.2    Canny, B.J.3    Michell, B.J.4    Kemp, B.E.5    Mcconell, G.K.6
  • 49
    • 0031009673 scopus 로고    scopus 로고
    • Contraction-induced changes in acetyl-CoA carboxylase and 5′-AMP-activated kinase in skeletal muscle
    • VAVVAS, D., A. APAZIDIS, A. K. SAHA, et al. Contraction-induced changes in acetyl-CoA carboxylase and 5′-AMP-activated kinase in skeletal muscle. J. Biol. Chem. 272:13255-13261, 1997.
    • (1997) J. Biol. Chem. , vol.272 , pp. 13255-13261
    • Vavvas, D.1    Apazidis, A.2    Saha, A.K.3
  • 50
    • 0032792665 scopus 로고    scopus 로고
    • The AMP-activated protein kinase, a metabolic master switch: Possible roles in Type 2 diabetes
    • WINDER, W. W., and D. G. HARDIE. The AMP-activated protein kinase, a metabolic master switch: possible roles in Type 2 diabetes. Am. J. Physiol. 277:E1-E10, 1999.
    • (1999) Am. J. Physiol. , vol.277
    • Winder, W.W.1    Hardie, D.G.2
  • 51
    • 0029978799 scopus 로고    scopus 로고
    • Inactivation of acetyl-CoA carboxylase and activation of AMP-activated protein kinase in muscle during exercise
    • WINDER, W. W., and D. G. HARDIE. Inactivation of acetyl-CoA carboxylase and activation of AMP-activated protein kinase in muscle during exercise. Am. J. Physiol. 270:E299-E304, 1996.
    • (1996) Am. J. Physiol. , vol.270
    • Winder, W.W.1    Hardie, D.G.2
  • 52
    • 0033949848 scopus 로고    scopus 로고
    • Activation of AMP-activated protein kinase increases mitochondrial enzymes in skeletal muscle
    • WINDER, W. W., B. F. HOLMES, D. S. RUBINK, E. B. JENSEN, M. CHEN, and J. O. HOLLOSZY. Activation of AMP-activated protein kinase increases mitochondrial enzymes in skeletal muscle. J. Appl. Physiol. 88:2219-2226, 2000.
    • (2000) J. Appl. Physiol. , vol.88 , pp. 2219-2226
    • Winder, W.W.1    Holmes, B.F.2    Rubink, D.S.3    Jensen, E.B.4    Chen, M.5    Holloszy, J.O.6
  • 53
    • 15444339308 scopus 로고    scopus 로고
    • Phosphorylation of rat muscle acetyl-CoA carboxylase by AMP-activated protein kinase and cAMP-dependent protein kinase
    • WINDER, W. W., H. A. WILSON, D. G. HARDIE, et al. Phosphorylation of rat muscle acetyl-CoA carboxylase by AMP-activated protein kinase and cAMP-dependent protein kinase. J. Appl. Physiol. 82:219-225, 1997.
    • (1997) J. Appl. Physiol. , vol.82 , pp. 219-225
    • Winder, W.W.1    Wilson, H.A.2    Hardie, D.G.3
  • 54
    • 0037375970 scopus 로고    scopus 로고
    • Regulation of 5′AMP-activated protein kinase activity and substrate utilization in exercising human skeletal muscle
    • WOJTASZEWSKI, J. F., C. MACDONALD, J. N. NIELSEN, et al. Regulation of 5′AMP-activated protein kinase activity and substrate utilization in exercising human skeletal muscle. Am. J. Physiol. Endocrinol. Metab. 284:E813-E822, 2003.
    • (2003) Am. J. Physiol. Endocrinol. Metab. , vol.284
    • Wojtaszewski, J.F.1    Macdonald, C.2    Nielsen, J.N.3
  • 55
    • 0034306362 scopus 로고    scopus 로고
    • Isoform-specific and exercise intensity-dependent activation of 5′-AMP-activated protein kinase in human skeletal muscle
    • WOJTASZEWSKI, J. F., P. NIELSEN, B. F. HANSEN, E. A. RICHTER, and B. KIENS. Isoform-specific and exercise intensity-dependent activation of 5′-AMP-activated protein kinase in human skeletal muscle. J. Physiol. 528:221-226, 2000.
    • (2000) J. Physiol. , vol.528 , pp. 221-226
    • Wojtaszewski, J.F.1    Nielsen, P.2    Hansen, B.F.3    Richter, E.A.4    Kiens, B.5
  • 56
    • 0036064261 scopus 로고    scopus 로고
    • Glycogen-dependent effects of AICA riboside on AMP-activated protein kinase and glycogen synthase activities in rat skeletal muscle
    • WOJTASZEWSKI, J. F. P., S. B. JØRGENSEN, Y. HELLSTEN, D. G. HARDIE, and E. A. RICHTER. Glycogen-dependent effects of AICA riboside on AMP-activated protein kinase and glycogen synthase activities in rat skeletal muscle. Diabetes 51:284-292, 2002.
    • (2002) Diabetes , vol.51 , pp. 284-292
    • Wojtaszewski, J.F.P.1    JØrgensen, S.B.2    Hellsten, Y.3    Hardie, D.G.4    Richter, E.A.5
  • 57
    • 0035914324 scopus 로고    scopus 로고
    • Regulation of transcription by AMP-activated Protein Kinase. Phosphorylation of p300 blocks its interaction with nuclear receptors
    • YANG, W., Y. H. HONG, X. Q. SHEN, C. FRANKOWSKI, H. S. CAMP, and T. LEFF. Regulation of transcription by AMP-activated Protein Kinase. Phosphorylation of p300 blocks its interaction with nuclear receptors. J. Biol. Chem. 276:38341-38344, 2001.
    • (2001) J. Biol. Chem. , vol.276 , pp. 38341-38344
    • Yang, W.1    Hong, Y.H.2    Shen, X.Q.3    Frankowski, C.4    Camp, H.S.5    Leff, T.6
  • 58
    • 0034863102 scopus 로고    scopus 로고
    • Regulation of muscle GLUT-4 transcription by AMP-activated protein kinase
    • ZHENG, D., P. S. MACLEAN, S. C. POHNERT, et al. Regulation of muscle GLUT-4 transcription by AMP-activated protein kinase. J. Appl. Physiol. 91:1073-1083, 2001.
    • (2001) J. Appl. Physiol. , vol.91 , pp. 1073-1083
    • Zheng, D.1    Maclean, P.S.2    Pohnert, S.C.3
  • 59
    • 0034773404 scopus 로고    scopus 로고
    • Role of AMP-activated protein kinase in mechanism of metformin action
    • ZHOU, G., R. MYERS, Y. LI, et al. Role of AMP-activated protein kinase in mechanism of metformin action. J. Clin. Invest. 108: 1167-1174, 2001.
    • (2001) J. Clin. Invest. , vol.108 , pp. 1167-1174
    • Zhou, G.1    Myers, R.2    Li, Y.3
  • 60
    • 0037058977 scopus 로고    scopus 로고
    • AMP kinase is required for mitochondrial biogenesis in skeletal muscle in response to chronic energy deprivation
    • ZONG, H., J. M. REN, L. H. YOUNG, et al. AMP kinase is required for mitochondrial biogenesis in skeletal muscle in response to chronic energy deprivation. Proc. Natl. Acad. Sci. USA 99:15983-15987, 2002.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 15983-15987
    • Zong, H.1    Ren, J.M.2    Young, L.H.3


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