Structure of the ligand-binding domain of rat VDR in complex with the nonsecosteroidal vitamin D3 analogue YR301

Acta Crystallographica Section F: Structural Biology and Crystallization Communications

Volumn 64, Issue 11, 2008, Pages 970-973

  Kakuda, Shinji ^a   Okada, Kazuhisa ^a   Eguchi, Hiroshi ^a   Takenouchi, Kazuya ^a   Hakamata, Wataru ^b   Kurihara, Masaaki ^b   Takimoto Kamimura, Midori ^a  

^a Teijin Institute for Biomedical Research   (Japan)

^b NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

Author keywords

Nuclear receptors; Vitamin D receptors; Vitamin D3 analogues

Indexed keywords

BIPHENYL DERIVATIVE; CALCITRIOL RECEPTOR; DRUG DERIVATIVE; VITAMIN D; YR301;

ANIMAL; ARTICLE; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; GENETICS; METABOLISM; MOLECULAR GENETICS; PROTEIN BINDING; PROTEIN TERTIARY STRUCTURE; RAT; X RAY CRYSTALLOGRAPHY;

ANIMALS; BINDING SITES; BIPHENYL COMPOUNDS; CRYSTALLOGRAPHY, X-RAY; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RATS; RECEPTORS, CALCITRIOL; VITAMIN D;

RATTUS;

EID: 55949096169     PISSN: 17443091     EISSN: 17443091     Source Type: Journal    
DOI: 10.1107/S1744309108026754     Document Type: Article

References (15)

1. Bouillon, R., Okamura, W. H. & Norman, A. W. (1995). Endocr. Rev. 16, 200-257.
2. Collaborative Computational Project, Number 4 (1994). Acta Cryst. D50, 760-763.
3. Emsley, P. & Cowtan, K. (2004). Acta Cryst. D60, 2126-2132.
4. Hakamata, W., Sato, Y., Okuda, H., Honzawa, S., Saito, N., Kishimoto, S., Yamashita, A., Sugiura, T., Kittaka, A. & Kurihara, M. (2008). Bioorg. Med. Chem. Lett. 18, 120-123.
5. Hendy, G. N., Hruska, K. A., Mathew, S. & Goltzman, D. (2006). Kidney Int. 69, 218-223.
6. Kalkhoven, E., Valentine, J. E., Heery, D. M. & Parker, M. G. (1998). EMBO J. 17, 232-243.
7. Lieberherr, M. (1987). Biol. Chem. 262, 13168-13173.
8. Mangelsdorf, D. J., Thummel, C., Beato, M., Herrlich, P., Schütz, G., Umesono, K., Blumberg, B., Kastner, P., Mark, M., Chambon, P. & Evans, R. M. (1995). Cell, 83, 835-839.
9. Mizwicki, M. T. & Norman, A. W. (2003). J. Bone Miner. Res. 18, 795-806.
10. Murshudov, G. N., Vagin, A. A. & Dodson, E. J. (1997). Acta Cryst. D53, 240-255.
11. Otwinowski, Z. & Minor, W. (1997). Methods Enzymol. 276, 307-326.
12. Rachez, C., Lemon, B. D., Suldan, Z., Bromleigh, V. & Gamble, M. (1999). Nature (London), 398, 824-828.
13. Stein, M. S. & Wark, J. D. (2003). Expert Opin. Invest. Drugs. 12, 825-840.
14. Vagin, A. & Teplyakov, A. (1997). J. Appl. Cryst. 30, 1022-1025.
15. Vanhooke, J. L., Benning, M. M., Bauer, C. B., Pike, J. W. & DeLuca, H. F. (2004). Biochemistry, 43, 4101-4110.