Individual binding pockets of importin-β for FG-nucleoporins have different binding properties and different sensitivities to RanGTP

Proceedings of the National Academy of Sciences of the United States of America

Volumn 105, Issue 42, 2008, Pages 16101-16106

  Otsuka, Shotaro ^a   Iwasaka, Shizuka ^a   Yoneda, Yoshihiro ^b   Takeyasu, Kunio ^a   Yoshimura, Shige H ^a,c  

^a KYOTO UNIVERSITY   (Japan)

^b OSAKA UNIVERSITY   (Japan)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

Nuclear import; Nuclear pore complex; Nuclear transport; Scanning probe microscopy; Single molecule force measurement

Indexed keywords

KARYOPHERIN BETA; NUCLEOPORIN; RAN PROTEIN;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; ATOMIC FORCE MICROSCOPY; CONFORMATIONAL TRANSITION; MUTANT; NONHUMAN; OOCYTE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN MOTIF; XENOPUS;

ANIMALS; BETA KARYOPHERINS; BINDING SITES; FEMALE; GLYCINE; HUMANS; MICE; MICROSCOPY, ATOMIC FORCE; MODELS, MOLECULAR; MUTATION; NUCLEAR PORE COMPLEX PROTEINS; OOCYTES; PHENYLALANINE; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RAN GTP-BINDING PROTEIN; SUBSTRATE SPECIFICITY; XENOPUS LAEVIS;

EID: 55849144420     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0802647105     Document Type: Article

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