Disorder in the nuclear pore complex: The FG repeat regions of nucleoporins are natively unfolded

Proceedings of the National Academy of Sciences of the United States of America

Volumn 100, Issue 5, 2003, Pages 2450-2455

  Denning, Daniel P ^a   Patel, Samir S ^a   Uversky, Vladimir ^b,c   Fink, Anthony L ^b   Rexach, Michael ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c INSTITUTE FOR BIOLOGICAL INSTRUMENTATION   (Russian Federation)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCINE; KARYOPHERIN; NUCLEOPORIN; PHENYLALANINE;

AMINO ACID SEQUENCE; ARTICLE; CELL NUCLEUS MEMBRANE; EUKARYOTIC CELL; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; NUCLEAR PORE COMPLEX; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FAMILY; PROTEIN FOLDING; PROTEIN TRANSPORT; SACCHAROMYCES CEREVISIAE;

ACTIVE TRANSPORT, CELL NUCLEUS; AMINO ACIDS; BIOPHYSICS; BLOTTING, WESTERN; CELL NUCLEUS; CHROMATOGRAPHY, GEL; CIRCULAR DICHROISM; ENDOPEPTIDASE K; ENDOPEPTIDASES; GLYCINE; NUCLEAR PORE; PHENYLALANINE; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY; RECOMBINANT PROTEINS; SACCHAROMYCES CEREVISIAE; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; SUCROSE; TIME FACTORS;

EUKARYOTA; SACCHAROMYCES CEREVISIAE;

EID: 0037418190     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0437902100     Document Type: Article

References (37)

1. Rout, M. & Aitchison, J. (2001) J. Biol. Chem. 276, 16593-16596.
2. Yang, Q., Rout, M. P. & Akey, C. W. (1998) Mol. Cell 1, 223-234.
3. Rexach, M. & Blobel, G. (1995) Cell 83, 683-692.
4. Allen, N., Huang, L., Burlingame, A. & Rexach, M. (2001) J. Biol. Chem. 276, 29268-29274.
5. Gorlich, D. & Kutay, U. (1999) Annu. Rev. Cell. Dev. Biol. 15, 607-660.
6. Buss, F., Kent, H., Stewart, M., Bailer, S. M. & Hanover, J. A. (1994) J. Cell Sci. 107, 631-638.
7. Ribbeck, K. & Gorlich, D. (2001) EMBO J. 20, 1320-1330.
8. Macara, I. G. (2001) Microbiol. Mol. Biol. Rev. 65, 570-594.
9. Bayliss, R., Kent, H. M., Corbett, A. H. & Stewart, M. (2000) J. Struct. Biol. 131, 240-247.
10. Denning, D. P., Uversky, V., Patel, S. S., Fink, A. L. & Rexach, M. (2002) J. Biol. Chem. 277, 33447-33455.
11. Uversky, V. N., Gillespie, J. R. & Fink, A. L. (2000) Proteins Struct. Funct. Genet. 41, 415-427.
12. Dunker, A. K., Lawson, J. D., Brown, C. J., Williams, R. M., Romero, P., Oh, J. S., Oldfield, C. J., Campen, A. M., Ratliff, C. M., Hipps, K. W., et al. (2001) J. Mol. Graphics Modeling 19, 26-59.
13. Denning, D., Mykytka, B., Allen, N., Huang, L., Burlingame, A. & Rexach, M. (2001) J. Cell Biol. 154, 937-950.
14. Siegel, L. M. & Monty, K. J. (1966) Biochim. Biophys. Acta 112, 346-362.
15. McEwen, C. R. (1967) Anal. Biochem. 20, 114-149.
16. Aris, J. P. & Blobel, G. (1991) Methods Enzymol. 194, 735-749.
17. Uversky, V. N. (2002) Protein Sci. 11, 739-756.
18. Rout, M. P. & Wente, S. R. (1994) Trends Cell Biol. 4, 357-365.
19. Dingwall, C., Kandels-Lewis, S. & Seraphin, B. (1995) Proc. Natl. Acad. Sci. USA 92, 7525-7529.
20. Taura, T., Krebber, H. & Silver, P. A. (1998) Proc. Natl. Acad. Sci. USA 95, 7427-7432.
21. Bailer, S. M., Balduf, C. & Hurt, E. (2001) Mol. Cell. Biol. 21, 7944-7955.
22. Del Priore, V., Heath, C., Snay, C., MacMillan, A., Gorsch, L., Dagher, S. & Cole, C. (1997) J. Cell Sci. 110, 2987-2999.
23. Schlaich, N. L., Haner, M., Lustig, A., Aebi, U. & Hurt, E. C. (1997) Mol. Biol. Cell 8, 33-46.
24. Huang, L., Baldwin, M. A., Maltby, D. A., Medzihradszky, K. F., Baker, P. R., Allen, N., Rexach, M., Edmondson, R. D., Campbell, J., Juhasz, P., et al. (2002) Mol. Cell. Proteomics 1, 434-450.
25. Allen, N. P., Patel, S. S., Lutzmann, M., Hurt, E., Huang, L., Burlingame, A. & Rexach, M. (2002) Mol. Cell. Proteomics, 1, 930-946.
26. Uversky, V. N. (2002) Eur. J. Biochem. 269, 1-10.
27. Cohen, C. & Parry, D. A. D. (1990) Proteins Struct. Funct. Genet. 7, 1-15.
28. Conti, E., Uy, M., Leighton, L., Blobel, G. & Kuriyan, J. (1998) Cell 94, 193-204.
29. Cingolani, G., Petosa, C., Weis, K. & Muller, C. W. (1999) Nature 399, 221-229.
30. Rout, M. P., Aitchison, J. D., Suprapto, A., Hjertaas, K. Zhao, Y. & Chait, B. T. (2000) J. Cell Biol. 148, 635-651.
31. Hood, J. K., Casolari, J. M. & Silver, P. A. (2000) J. Cell Sci. 113, 1471-1480.
32. Solsbacher, J., Maurer, P., Vogel, F. & Schlenstedt, G. (2000) Mol. Cell. Biol. 20, 8468-8479.
33. Belgareh, N., Snay-Hodge, C., Pasteau, F., Dagher, S., Cole, C. N. & Doye, V. (1998) Mol. Biol. Cell 9, 3475-3492.
34. Dyson, H. J. & Wright, P. E. (2002) Curr. Opin. Struct. Biol. 12, 54-60.
35. Gilchrist, D., Mykytka, B. & Rexach, M. (2002) J. Biol. Chem. 277, 18161-18172.
36. Bayliss, R., Littlewood, T. & Stewart, M. (2000) Cell 102, 99-108.
37. Guan, T., Muller, S., Klier, G., Pante, N., Blevitt, J. M., Haner, M., Paschal, B., Aebi, U. & Gerace, L. (1995) Mol. Biol. Cell 6, 1591-1603.