African HIV/AIDS trials are more likely to report adequate allocation concealment and random generation than North American trials

PLoS ONE

Volumn 3, Issue 10, 2008, Pages

  Siegfried, Nandi ^a,b,d   Clarke, Michael ^a,b   Volmink, Jimmy ^c,d   van der Merwe, Lize ^d,e  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UK COCHRANE CENTRE   (United Kingdom)

^c UNIVERSITY OF STELLENBOSCH   (South Africa)

^d SOUTH AFRICAN MEDICAL RESEARCH COUNCIL   (South Africa)

^e UNIVERSITY OF THE WESTERN CAPE   (South Africa)

Author keywords

[No Author keywords available]

Indexed keywords

ACQUIRED IMMUNE DEFICIENCY SYNDROME; AFRICA; ARTICLE; BIOINFORMATICS; CLINICAL TRIAL; DATA EXTRACTION; GEOGRAPHIC DISTRIBUTION; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS; INTERMETHOD COMPARISON; MEDICAL RESEARCH; MEDLINE; METHODOLOGY; NORTH AMERICA; QUALITY CONTROL; RESOURCE ALLOCATION; CLINICAL PROTOCOL; COMPARATIVE STUDY; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; RANDOMIZED CONTROLLED TRIAL; REGRESSION ANALYSIS; STANDARD; TREATMENT OUTCOME;

ACQUIRED IMMUNODEFICIENCY SYNDROME; AFRICA; CLINICAL PROTOCOLS; HIV INFECTIONS; NORTH AMERICA; RANDOMIZED CONTROLLED TRIALS AS TOPIC; REGRESSION ANALYSIS; TREATMENT OUTCOME;

EID: 55849085415     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0003491     Document Type: Article

References (36)

1. Schulz KF (1995) Unbiased research and the human spirit: the challenges of randomized controlled trials. CMAJ 153: 783-786.
2. Kjaergard LL, Nikolova D, Gluud C (1999) Randomized clinical trials in HEPATOLOGY: predictors of quality. Hepatology 30: 1134-1138.
3. Kjaergard LL, Gluud C (2002) Funding, disease area, and internal validity of hepatobiliary randomized clinical trials. American Journal of Gastroenterology 97: 2708-2713.
4. Chan A-W, Altman DG (2005) Identifying outcome reporting bias in randomised trials on PubMed: review of publications ad survey of authors. BMJ 330: 753-756.
5. Ruiz-Canela M, de Irala-Estevez J, Martinez-Gonzalez MA, Gomez-Gracia E, Fernandez-Crehuet J (2001) Methodological quality and reporting of ethical requirements in clinical trials. Journal of Medical Ethics 27: 172-176.
6. Boutron I, Tubach F, Giraudeau B, Ravaud P (2003) Methodological differences in clinical trials evaluating nonpharmacoogical and pharmacological treatments of hip and knee osteoarthritis. JAMA 290: 1062-1070.
7. Gluud LL, Sorensen TI, Gotzsche PC, Gluud C (2005) The journal impact factor as a predictor of trial quality and outcomes: cohort study of hepatobiliary randomized clinical trials. American Journal of Gastroenterology 100: 2431-2435.
8. Balasubramanian SP, Wiener M, Alshameeri Z, Tiruvoipati R, Elbourne D, et al. (2006) Standards of reporting of randomized controlled trials in general surgery: can we do better? Annals of Surgery 244: 663-667.
9. Edejer TT (1999) North-South research partnerships: the ethics of carrying out research in developing countries. BMJ 319: 438-441.
10. Anonymous (2000) Editorial: enabling research in developing countries. Lancet 356: 1043.
11. Gonzalez-Block MA (2004) Health policy and systems research agendas in developing countries. Health Research Policy and Systems 2: 6.
12. Lurie P, Wolfe SM (1997) Unethical trials of interventions to reduce perinatal transmission of the human immunodeficiency virus in developing countries. New England Journal of Medicine 337: 853-856.
13. Ballantyne A (2005) HIV International clinical research: exploitation and risk. Bioethics 19: 476-491.
14. Committee on reviewing the HIVNET 012 Perinatal HIV Prevention Study Board on Population Health and Public Health Practice Institute of Medicine of the National Academies (2005) Review of the HIVNET 012 Perinatal HIV Prevention Study. Washington, D.C.: The National Academies Press.
15. Siegfried N, Clarke M, Volmink J (2005) Randomised controlled trials in Africa of HIV and AIDS: descriptive study and spatial distribution. BMJ 331: 742.
16. Encyclopaedia Britannica (2007) North America. Encyclopaedia Britannica Online.
17. Jüni P, Altman DG, Egger M (2001) Assessing the quality of randomised controlled trials. In: Egger M, Davey-Smith G, Altman DG, eds. Systematic reviews in health care: meta-analysis in context. London: BMJ Publishing Group. pp 87-108.
18. Hosmer D, Lemeshow S (2000) Applied logistic regression. New York: John Wiley & Sons, Ltd.
19. Moher D, Schulz KF, Altman DG (2001) The CONSORT Statement: revised recommendations for improving the quality of reports of parallel-group randomized trials. Lancet 357: 1191-1194.
20. Egger M, Jüni P, Bartlett C (2001) Value of flow diagrams in reports of randomized controlled trials. JAMA 285: 1996-1999.
21. Altman D (1991) Practical statistics for medical research. London: Chapman and Hall.
22. Altman DG, Schulz KF, Moher D, Egger M, Davidoff F, et al. (2001) The revised CONSORT statement for reporting randomized trials: explanation and elaboration. Annals of Internal Medicine 134: 663-694.
23. Groopman JE, Gottlieb MS, Goodman J, Mitsuyasu RT, Conant MA, et al. (1984) Recombinant alpha-2 interferon therapy for Kaposi's sarcoma associated with the acquired immunodeficiency syndrome. Annals of Internal Medicine 100: 671-676.
24. Crumley ET, Wiebe N, Cramer K, Klassen TP, Hartling L (2005) Which resources should be used to identify RCT/CCTs for systematic reviews: a systematic review. BMC Medical Research Methodology 5: 24.
25. Edwards P, Clarke M, DiGuiseppi C, Pratap S, Roberts I, et al. (2002) Identification of randomized controlled trials in systematic reviews: accuracy and reliability of screening records. Statistics in Medicine 21: 1635-1640.
26. Royston P, Altman D, Sauerbrei W (2006) Dichotomizing continuous predictors in multiple regression: a bad idea. Statistics in Medicine 25: 127-141.
27. Schulz KF, Chalmers I, Hayes RJ, Altman DG (1995) Empirical evidence of bias. Dimensions of methodological quality associated with estimates of treatment effects in controlled trials. JAMA 273: 408-412.
28. Schulz KF, Altman DG, Moher D (2002) Allocation concealment in clinical trials. JAMA 288: 2406-2407.
29. Soares HP, Daniels S, Kumar A, Clarke M, Scott C, et al. (2004) Bad reporting does not mean bad methods for randomised trials: observational study of randomised controlled trials performed by the Radiation Therapy Oncology Group. BMJ 328: 22-24.
30. Seglen PO (1997) Why the impact factor of journals should not be used for evaluating research. BMJ 314.
31. Ha TC, Tan SB, Soo KC (2006) The journal impact factor: too much of an impact? Annals of the Academy of Medicine, Singapore 35: 911-916.
32. United States National Library of Medicine National Institutes of Health (2007) Abridged Index Medicus (AIM) Journal Titles. Available from: http://www.nlm.nih.gov/bsd/aim.html [Accessed 12 January 2007].
33. Cohen J (2000) Balancing the collaboration equation. Science 288: 2155-2159.
34. Horton R (2000) North and South: bridging the information gap. Lancet 355: 2231-2236.
35. Yousefi-Nooraie R, Shakiba B, Mortaz-Hejri S (2006) Country development and manuscript selection bias: a review of published studies. BMC Medical Research Methodology 6: 37.
36. Sim I, Chan AW, Gulmezoglu AM, Evans T, Pang T (2006) Clinical trial registration: transparency is the watchword. Lancet 367: 1631-1633.