High expression of human nonmetastatic clone 23 type 1 in cancer of uterine cervix and its association with poor cell differentiation and worse overall survival

Journal of Surgical Oncology

Volumn 98, Issue 6, 2008, Pages 448-456

  Hsu, Chien Gang ^a,b   Lin, Long Yau ^a,c   Ko, Jiunn Liang ^a   Yang, Shun Fa ^a   Chang, Han ^a   Lin, Ching Yi ^c   Tsai, Hsiu Ting ^a   Chen, Shiuan Chih ^a,c   Chen, Shu Chen ^d   Wang, Po Hui ^a,c  

^a CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^b Da Chien General Hospital   (Taiwan)

^c CHUNG SHAN MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^d CENTRAL TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Taiwan)

Author keywords

Cancer of uterine cervix; Cell differentiation; Human nonmetastatic clone 23 type 1; Overall survival; Real time polymerase chain reaction; Tissue microarray

Indexed keywords

MESSENGER RNA;

ARTICLE; CANCER INVASION; CANCER PATIENT; CANCER RECURRENCE; CANCER STAGING; CANCER SURVIVAL; CANCER TISSUE; CELL DIFFERENTIATION; CLINICAL ARTICLE; CONTROLLED STUDY; GENE; GENE EXPRESSION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LYMPH NODE METASTASIS; NONMETASTATIC CLONE 23 TYPE 1 GENE; OVERALL SURVIVAL; PRIORITY JOURNAL; TISSUE MICROARRAY; TUMOR VOLUME; UTERINE CERVIX CANCER;

CELL DIFFERENTIATION; FEMALE; FOLLOW-UP STUDIES; HUMANS; IMMUNOHISTOCHEMISTRY; LYMPHATIC METASTASIS; NEOPLASM INVASIVENESS; NEOPLASM RECURRENCE, LOCAL; NM23 NUCLEOSIDE DIPHOSPHATE KINASES; POLYMERASE CHAIN REACTION; RNA, MESSENGER; UTERINE CERVICAL NEOPLASMS;

EID: 55749115078     PISSN: 00224790     EISSN: 10969098     Source Type: Journal    
DOI: 10.1002/jso.21127     Document Type: Article

References (46)

1. Steeg PS, Bevilacqua G, Kopper L, et al.: Evidence for a novel gene associated with low tumor metastatic potential. J Natl Cancer Inst 1988;80:200-204.
2. Rosengard AM, Krutzsch HC, Shearn A, et al.: Reduced Nm23/ Awd protein in tumour metastasis and aberrant Drosophila development. Nature 1989;342:177-180.
3. Wallet V, Mutzel R, Troll H, et al.: Dictyostelium nucleoside diphosphate kinase highly homologous to Nm23 and Awd proteins involved in mammalian tumor metastasis and Drosophila development. J Natl Cancer Inst 1990;82:1199-1202.
4. Kimura N, Shimada N, Nomura K, et al.: Isolation and characterization of a cDNA clone encoding rat nucleoside diphosphate kinase. J Biol Chem 1990;265:15744-15749.
5. Lacombe ML, Milon L, Munier A, et al.: The human Nm23/ nucleoside diphosphate kinases. J Bioenerg Biomembr 2000;32:247-258.
6. Ouatas T, Salerno M, Palmieri D, et al.: Basic and translational advances in cancer metastasis: Nm23. J Bioenerg Biomembr 2003;35:73-79.
7. Postel EH: NM23-NDP kinase. Int J Biochem Cell Biol 1998;30:1291-1295.
8. Crawford RM, Treharne KJ, Best OG, et al.: A novel physical and functional association between nucleoside diphosphate kinase A and AMP-activated protein kinase alpha1 in liver and lung. Biochem J 2005;392:201-209.
9. Sirotkovic-Skerlev M, Krizanac S, Kapitanovic S, et al.: Expression of c-myc, erbB-2, p53 and nm23-H1 gene product in benign and malignant breast lesions: Coexpression and correlation with clinicopathologic parameters. Exp Mol Pathol 2005;79:42-50.
10. Muller W, Schneiders A, Hommel G, et al.: Expression of nm23 in gastric carcinoma: Association with tumor progression and poor prognosis. Cancer 1998;83:2481-2487.
11. Lee CS, Pirdas A, Lee MW: Immunohistochemical demonstration of the nm23-H1 gene product in human malignant melanoma and Spitz nevi. Pathology 1996;28:220-224.
12. Kapitanovic S, Cacev T, Berkovic M, et al.: nm23-H1 expression and loss of heterozygosity in colon adenocarcinoma. J Clin Pathol 2004;57:1312-1318.
13. Leone A, Seeger RC, Hong CM, et al.: Evidence for nm23 RNA overexpression, DNA amplification and mutation in aggressive childhood neuroblastomas. Oncogene 1993;8:855-865.
14. Oda Y, Naka T, Takeshita M, et al.: Comparison of histological changes and changes in nm23 and c-MET expression between primary and metastatic sites in osteosarcoma: A clinicopathologic and immunohistochemical study. Hum Pathol 2000;31:709-716.
15. Tas F, Tuzlali S, Aydiner A, et al.: Prognostic role of nm23 gene expression in patients with ovarian cancer. Am J Clin Oncol 2002;25:164-167.
16. Tomic S, Ilic Forko J, Babic D, et al.: c-erbB-2, p53, and nm23 proteins as prognostic factors in patients with epithelial ovarian carcinoma. Croat Med J 2003;44:429-434.
17. Wang PH, Chang H, Ko JL, et al.: Nm23-H1 immunohistochemical expression in multisteps of cervical carcinogenesis. Int J Gynecol Cancer 2003;13:325-330.
18. Wang PH, Ko JL, Chang H, et al.: Clinical significance of high nm23-H1 expression in intraepithelial neoplasia and early-stage squamous cell carcinoma of the uterine cervix. Gynecol Obstet Invest 2003;55:14-19.
19. Chen HY, Hsu CT, Lin WC, et al.: Prognostic value of nm23 expression in stage IB1 cervical carcinoma. Jpn J Clin Oncol 2001;31:327-332.
20. Mandai M, Konishi I, Koshiyama M, et al.: Altered expression of nm23-H1 and c-erbB-2 proteins have prognostic significance in adenocarcinoma but not in squamous cell carcinoma of the uterine cervix. Cancer 1995;75:2523-2529.
21. Olaussen KA, Dunant A, Fouret P, et al.: DNA repair by ERCC1 in non-small-cell lung cancer and cisplatin-based adjuvant chemotherapy. N Engl J Med 2006;355:983-991.
22. Al-Haddad S, Zhang Z, Leygue E, et al.: Psoriasin (S100A7) expression and invasive breast cancer. Am J Pathol 1999;155:2057-2066.
23. Handra-Luca A, Bilal H, Bertrand JC, et al.: Extra-cellular signal-regulated ERK-1/ERK-2 pathway activation in human salivary gland mucoepidermoid carcinoma: Association to aggressive tumor behavior and tumor cell proliferation. Am J Pathol 2003;163:957-967.
24. Chang H, Su JM, Huang CC, et al.: Using a combination of cytochrome P450 1B1 and beta-catenin for early diagnosis and prevention of colorectal cancer. Cancer Detect Prev 2005;29:562-569.
25. Wang PH, Chang H, Ko JL, et al.: Nm23-H1 immunohistochemical expression in multisteps of cervical carcinogenesis. Int J Gynecol Cancer 2003;13:325-330.
26. Postel EH: Multiple biochemical activities of NM23/NDP kinase in gene regulation. J Bioenerg Biomembr 2003;35:31-40.
27. Malins DC, Polissar NL, Schaefer S, et al.: A unified theory of carcinogenesis based on order-disorder transitions in DNA structure as studied in the human ovary and breast. Proc Natl Acad Sci 1998;95:7637-7642.
28. Malins DC, Polissar NL, Gunselman SJ: Progression of human breast cancers to the metastatic state is linked to hydroxyl radical-induced DNA damage. Proc Natl Acad Sci 1996;93:2557-2563.
29. Zhang L, Zhou W, Velculescu VE, et al.: Gene expression profiles in normal and cancer cells. Science 1997;276:1268-1272.
30. Lombardi D, Lacombe ML, Paggi MG: nm23: Unraveling its biological function in cell differentiation. J Cell Physiol 2000;182:144-149.
31. Pinon VP, Millot G, Munier A, et al.: Cytoskeletal association of the A and B nucleoside diphosphate kinases of interphasic but not mitotic human carcinoma cell lines: Specific nuclear localization of the B subunit. Exp Cell Res 1999;246:355-367.
32. Yamashiro S, Urano T, Shiku H, et al.: Alteration of nm23 gene expression during the induced differentiation of human leukemia cell lines. Oncogene 1994;9:2461-2468.
33. Sager R: Expression genetics in cancer: Shifting the focus from DNA to RNA. Proc Natl Acad Sci 1997;94:952-955.
34. Valentijn LJ, Koppen A, van Asperen R, et al.: Inhibition of a new differentiation pathway in neuroblastoma by copy number defects of N-myc, Cdc42, and nm23 genes. Cancer Res 2005;65:3136-3145.
35. Marone M, Scambia G, Ferrandina G, et al.: Nm23 expression in endometrial and cervical cancer: Inverse correlation with lymph node involvement and myometrial invasion. Br J Cancer 1996;74:1063-1068.
36. Reymond A, Volorio S, Merla G, et al.: Evidence for interaction between human PRUNE and nm23-H1 NDPKinase. Oncogene 1999;18:7244-7252.
37. Forus A, D'Angelo A, Henriksen J, et al.: Amplification and overexpression of PRUNE in human sarcomas and breast carcinomas-a possible mechanism for altering the nm23-H1 activity. Oncogene 2001;20:6881-6890.
38. D'Angelo A, Garzia L, Andre A, et al.: Prune cAMP phosphodiesterase binds nm23-H1 and promotes cancer metastasis. Cancer Cell 2004;5:137-149.
39. Zollo M, Andre A, Cossu A, et al.: Overexpression of h-prune in breast cancer is correlated with advanced disease status. Clin Cancer Res 2005;11:199-205.
40. Marino N, Zollo M: Understanding h-prune biology in the fight against cancer. Clin Exp Metastasis 2007;24:637-645.
41. Fan Z, Beresford PJ, Oh DY, et al.: Tumor suppressor NM23-H1 is a granzyme A-activated DNase during CTL-mediated apoptosis, and the nucleosome assembly protein SET is its inhibitor. Cell 2003;112:659-672.
42. Habets GG, Scholtes EH, Zuydgeest D, et al.: Identification of an invasion-inducing gene, Tiam-1, that encodes a protein with homology to GDP-GTP exchangers for Rho-like proteins. Cell 1994;77:537-549.
43. Otsuki Y, Tanaka M, Yoshii S, et al.: Tumor metastasis suppressor nm23H1 regulates Rac1 GTPase by interaction with Tiam1. Proc Natl Acad Sci 2001;98:4385-4390.
44. Valentijn LJ, Koster J, Versteeg R: Read-through transcript from NM23-H1 into the neighboring NM23-H2 gene encodes a novel protein NM23-LV. Genomics 2006;87:483-489.
45. Ni X, Gu S, Dai J, et al.: Isolation and characterization of a novel human NM23-H1B gene, a different transcript ofNM23-H1. J Hum Genet 2003;48:96-100.
46. Kristensen GB, Holm R, Abeler VM, et al.: Evaluation of the prognostic significance of nm23/NDP kinase protein expression in cervical carcinoma: An immunohistochemical study. Gynecol Oncol 1996;61:378-383.