메뉴 건너뛰기




Volumn 87, Issue 4, 2006, Pages 483-489

Read-through transcript from NM23-H1 into the neighboring NM23-H2 gene encodes a novel protein, NM23-LV

Author keywords

Alternative splicing; Neuroblastoma; NM23; NM23 LV; Read through transcript

Indexed keywords

MESSENGER RNA; NUCLEOSIDE DIPHOSPHATE KINASE; NUCLEOSIDE DIPHOSPHATE KINASE A; PROTEIN NM23; PROTEIN NM23 LV; TUMOR MARKER; UNCLASSIFIED DRUG;

EID: 33645081771     PISSN: 08887543     EISSN: 10898646     Source Type: Journal    
DOI: 10.1016/j.ygeno.2005.11.004     Document Type: Article
Times cited : (24)

References (42)
  • 2
    • 0023937268 scopus 로고
    • Evidence for a novel gene associated with low tumor metastatic potential
    • P.S. Steeg Evidence for a novel gene associated with low tumor metastatic potential J. Natl. Cancer Inst. 80 1988 200 204
    • (1988) J. Natl. Cancer Inst. , vol.80 , pp. 200-204
    • Steeg, P.S.1
  • 3
    • 0026457964 scopus 로고
    • Levels of nm23 messenger RNA in metastatic malignant melanomas: Inverse correlation to disease progression
    • V.A. Florenes Levels of nm23 messenger RNA in metastatic malignant melanomas: inverse correlation to disease progression Cancer Res. 52 1992 6088 6091
    • (1992) Cancer Res. , vol.52 , pp. 6088-6091
    • Florenes, V.A.1
  • 4
    • 0026428162 scopus 로고
    • Expression of the antimetastatic gene nm23 in human breast cancer: An association with good prognosis
    • C. Hennessy Expression of the antimetastatic gene nm23 in human breast cancer: an association with good prognosis J. Natl. Cancer Inst. 83 1991 281 285
    • (1991) J. Natl. Cancer Inst. , vol.83 , pp. 281-285
    • Hennessy, C.1
  • 5
    • 0036908850 scopus 로고    scopus 로고
    • Clinical significance of nm23 expression and chromosome 17 numerical aberrations in primary gastric cancer
    • R. Terada Clinical significance of nm23 expression and chromosome 17 numerical aberrations in primary gastric cancer Med. Oncol. 19 2002 239 248
    • (2002) Med. Oncol. , vol.19 , pp. 239-248
    • Terada, R.1
  • 6
    • 0025753514 scopus 로고
    • Reduced tumor incidence, metastatic potential, and cytokine responsiveness of nm23-transfected melanoma cells
    • A. Leone Reduced tumor incidence, metastatic potential, and cytokine responsiveness of nm23-transfected melanoma cells Cell 65 1991 25 35
    • (1991) Cell , vol.65 , pp. 25-35
    • Leone, A.1
  • 7
    • 0027304816 scopus 로고
    • Transfection of human nm23-H1 into the human MDA-MB-435 breast carcinoma cell line: Effects on tumor metastatic potential, colonization and enzymatic activity
    • A. Leone, U. Flatow, K. VanHoutte, and P.S. Steeg Transfection of human nm23-H1 into the human MDA-MB-435 breast carcinoma cell line: effects on tumor metastatic potential, colonization and enzymatic activity Oncogene 8 1993 2325 2333
    • (1993) Oncogene , vol.8 , pp. 2325-2333
    • Leone, A.1    Flatow, U.2    Vanhoutte, K.3    Steeg, P.S.4
  • 8
    • 0032887607 scopus 로고    scopus 로고
    • Inhibitory activity of nm23-H1 on invasion and colonization of human prostate carcinoma cells is not mediated by its NDP kinase activity
    • H.Y. Lee, and H. Lee Inhibitory activity of nm23-H1 on invasion and colonization of human prostate carcinoma cells is not mediated by its NDP kinase activity Cancer Lett. 145 1999 93 99
    • (1999) Cancer Lett. , vol.145 , pp. 93-99
    • Lee, H.Y.1    Lee, H.2
  • 9
    • 0027465480 scopus 로고
    • Evidence for nm23 RNA overexpression, DNA amplification and mutation in aggressive childhood neuroblastomas
    • A. Leone Evidence for nm23 RNA overexpression, DNA amplification and mutation in aggressive childhood neuroblastomas Oncogene 8 1993 855 865
    • (1993) Oncogene , vol.8 , pp. 855-865
    • Leone, A.1
  • 10
    • 0027501430 scopus 로고
    • High levels of nm23-H1 and nm23-H2 messenger RNA in human squamous-cell lung carcinoma are associated with poor differentiation and advanced tumor stages
    • M. Engel High levels of nm23-H1 and nm23-H2 messenger RNA in human squamous-cell lung carcinoma are associated with poor differentiation and advanced tumor stages Int. J. Cancer 55 1993 375 379
    • (1993) Int. J. Cancer , vol.55 , pp. 375-379
    • Engel, M.1
  • 11
    • 0027169499 scopus 로고
    • High levels of Nm23 gene expression in advanced stage of thyroid carcinomas
    • M. Zou, Y. Shi, S. Al-Sedairy, and N.R. Farid High levels of Nm23 gene expression in advanced stage of thyroid carcinomas Br. J. Cancer 68 1993 385 388
    • (1993) Br. J. Cancer , vol.68 , pp. 385-388
    • Zou, M.1    Shi, Y.2    Al-Sedairy, S.3    Farid, N.R.4
  • 12
    • 85047695614 scopus 로고    scopus 로고
    • The N-myc and c-myc downstream pathways include the chromosome 17q genes nm23-H1 and nm23-H2
    • M.B. Godfried The N-myc and c-myc downstream pathways include the chromosome 17q genes nm23-H1 and nm23-H2 Oncogene 21 2002 2097 2101
    • (2002) Oncogene , vol.21 , pp. 2097-2101
    • Godfried, M.B.1
  • 13
    • 0031409099 scopus 로고    scopus 로고
    • Gain of chromosome arm 17q predicts unfavourable outcome in neuroblastoma patients
    • M. Lastowska Gain of chromosome arm 17q predicts unfavourable outcome in neuroblastoma patients Eur. J. Cancer 33 1997 1627 1633
    • (1997) Eur. J. Cancer , vol.33 , pp. 1627-1633
    • Lastowska, M.1
  • 14
    • 0033600283 scopus 로고    scopus 로고
    • Gain of chromosome arm 17q and adverse outcome in patients with neuroblastoma
    • N. Bown Gain of chromosome arm 17q and adverse outcome in patients with neuroblastoma N. Engl. J. Med. 340 1999 1954 1961
    • (1999) N. Engl. J. Med. , vol.340 , pp. 1954-1961
    • Bown, N.1
  • 15
    • 0033592951 scopus 로고    scopus 로고
    • Interaction of the Ras-related protein associated with diabetes rad and the putative tumor metastasis suppressor NM23 provides a novel mechanism of GTPase regulation
    • J. Zhu Interaction of the Ras-related protein associated with diabetes rad and the putative tumor metastasis suppressor NM23 provides a novel mechanism of GTPase regulation Proc. Natl. Acad. Sci. USA 96 1999 14911 14918
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 14911-14918
    • Zhu, J.1
  • 16
    • 0035836637 scopus 로고    scopus 로고
    • Tumor metastasis suppressor nm23H1 regulates Rac1 by interaction with Tiam1
    • Y. Otsuki Tumor metastasis suppressor nm23H1 regulates Rac1 by interaction with Tiam1 Proc. Natl. Acad. Sci. USA 98 2001 4385 4390
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 4385-4390
    • Otsuki, Y.1
  • 17
    • 17144387910 scopus 로고    scopus 로고
    • Inhibition of a new differentiation pathway in neuroblastoma by copy number defects of N-myc, cdc42, and nm23 genes
    • L.J. Valentijn Inhibition of a new differentiation pathway in neuroblastoma by copy number defects of N-myc, cdc42, and nm23 genes Cancer Res. 65 2005 3136 3145
    • (2005) Cancer Res. , vol.65 , pp. 3136-3145
    • Valentijn, L.J.1
  • 18
    • 0028902716 scopus 로고
    • The association of the nm23-M1 protein and β-tubulin correlates with cell differentiation
    • D. Lombardi, A. Sacchi, G. D'Agostino, and G. Tibursi The association of the nm23-M1 protein and β-tubulin correlates with cell differentiation Exp. Cell Res. 217 1995 267 271
    • (1995) Exp. Cell Res. , vol.217 , pp. 267-271
    • Lombardi, D.1    Sacchi, A.2    D'Agostino, G.3    Tibursi, G.4
  • 19
    • 0033080406 scopus 로고    scopus 로고
    • Cytoskeletal association of the a and B nucleoside diphosphate kinases of interphasic but not mitotic human carcinoma cell lines: Specific nuclear localization of the B subunit
    • V.P. Pinon Cytoskeletal association of the A and B nucleoside diphosphate kinases of interphasic but not mitotic human carcinoma cell lines: specific nuclear localization of the B subunit Exp. Cell Res. 246 1999 355 367
    • (1999) Exp. Cell Res. , vol.246 , pp. 355-367
    • Pinon, V.P.1
  • 20
    • 0035862187 scopus 로고    scopus 로고
    • Identification of the tumor metastasis suppressor nm23-H1/nm23-R1 as a constituent of the centrosome
    • D. Roymans Identification of the tumor metastasis suppressor nm23-H1/nm23-R1 as a constituent of the centrosome Exp. Cell Res. 262 2001 145 153
    • (2001) Exp. Cell Res. , vol.262 , pp. 145-153
    • Roymans, D.1
  • 21
    • 0037036371 scopus 로고    scopus 로고
    • Integrin cytoplasmic domain-associated protein 1α (ICAP-1α) interacts directly with the metastatic suppressor nm23-H2, and both proteins are targeted to newly formed cell adhesion sites upon integrin engagement
    • H.-N. Fournier Integrin cytoplasmic domain-associated protein 1α (ICAP-1α) interacts directly with the metastatic suppressor nm23-H2, and both proteins are targeted to newly formed cell adhesion sites upon integrin engagement J. Biol. Chem. 277 2002 20895 20902
    • (2002) J. Biol. Chem. , vol.277 , pp. 20895-20902
    • Fournier, H.-N.1
  • 22
    • 0033518131 scopus 로고    scopus 로고
    • Evidence for interaction between human PRUNE and nm23-H1 NDPKinase
    • A. Reymond Evidence for interaction between human PRUNE and nm23-H1 NDPKinase Oncogene 18 1999 7244 7252
    • (1999) Oncogene , vol.18 , pp. 7244-7252
    • Reymond, A.1
  • 23
    • 0038546517 scopus 로고    scopus 로고
    • Protein interactions provide new insight into nm23/nucleoside diphosphate kinase functions
    • D. Lombardi, and A.M. Mileo Protein interactions provide new insight into nm23/nucleoside diphosphate kinase functions J. Bioenerg. Biomembr. 35 2003 67 71
    • (2003) J. Bioenerg. Biomembr. , vol.35 , pp. 67-71
    • Lombardi, D.1    Mileo, A.M.2
  • 24
    • 0037423932 scopus 로고    scopus 로고
    • Tumor suppressor NM23-H1 is a granzyme A-activated DNase during CTL-mediated apoptosis, and the nucleosome assembly protein SET is its inhibitor
    • Z. Fan, P.J. Beresford, D.Y. Oh, D. Zhang, and J. Lieberman Tumor suppressor NM23-H1 is a granzyme A-activated DNase during CTL-mediated apoptosis, and the nucleosome assembly protein SET is its inhibitor Cell 112 2003 659 672
    • (2003) Cell , vol.112 , pp. 659-672
    • Fan, Z.1    Beresford, P.J.2    Oh, D.Y.3    Zhang, D.4    Lieberman, J.5
  • 25
    • 0027293728 scopus 로고
    • Human c-myc transcription factor PuF identified as nm23-H2 nucleoside diphosphate kinase, a candidate suppressor of tumor metastasis
    • E.H. Postel, S.J. Berberich, S.J. Flint, and C.A. Ferrone Human c-myc transcription factor PuF identified as nm23-H2 nucleoside diphosphate kinase, a candidate suppressor of tumor metastasis Science 261 1993 478 480
    • (1993) Science , vol.261 , pp. 478-480
    • Postel, E.H.1    Berberich, S.J.2    Flint, S.J.3    Ferrone, C.A.4
  • 26
    • 0037059740 scopus 로고    scopus 로고
    • NM23-H1 and NM23-H2 repress transcriptional activities of nuclease-hypersensitive elements in the platelet-derived growth factor-A promoter
    • D. Ma NM23-H1 and NM23-H2 repress transcriptional activities of nuclease-hypersensitive elements in the platelet-derived growth factor-A promoter J. Biol. Chem. 277 2002 1560 1567
    • (2002) J. Biol. Chem. , vol.277 , pp. 1560-1567
    • Ma, D.1
  • 27
    • 0037106482 scopus 로고    scopus 로고
    • Tumour metastasis suppressor, nm23-β, inhibits gelatinase a transcription by interference with transactivator Y-box protein-1 (YB-1)
    • S. Cheng, M.A. Alfonso-Jaume, P.R. Mertens, and D.H. Lovett Tumour metastasis suppressor, nm23-β, inhibits gelatinase A transcription by interference with transactivator Y-box protein-1 (YB-1) Biochem. J. 366 2002 807 816
    • (2002) Biochem. J. , vol.366 , pp. 807-816
    • Cheng, S.1    Alfonso-Jaume, M.A.2    Mertens, P.R.3    Lovett, D.H.4
  • 28
    • 0037223782 scopus 로고    scopus 로고
    • Isolation and characterization of a novel human NM23-H1B gene, a different transcript of NM23-H1
    • X. Ni Isolation and characterization of a novel human NM23-H1B gene, a different transcript of NM23-H1 J. Hum. Genet. 48 2003 96 100
    • (2003) J. Hum. Genet. , vol.48 , pp. 96-100
    • Ni, X.1
  • 29
    • 0030976107 scopus 로고    scopus 로고
    • Nm23-H4, a new member of the family of human nm23/nucleoside diphosphate kinase genes localised on chromosome 16p13
    • L. Milon Nm23-H4, a new member of the family of human nm23/nucleoside diphosphate kinase genes localised on chromosome 16p13 Hum. Genet. 99 1997 550 557
    • (1997) Hum. Genet. , vol.99 , pp. 550-557
    • Milon, L.1
  • 30
    • 0034640519 scopus 로고    scopus 로고
    • The human nm23-H4 gene product is a mitochondrial nucleoside diphosphate kinase
    • L. Milon The human nm23-H4 gene product is a mitochondrial nucleoside diphosphate kinase J. Biol. Chem. 275 2000 14264 14272
    • (2000) J. Biol. Chem. , vol.275 , pp. 14264-14272
    • Milon, L.1
  • 31
    • 0032434324 scopus 로고    scopus 로고
    • A new human nm23 homologue (nm23-H5) specifically expressed in testis germinal cells
    • A. Munier A new human nm23 homologue (nm23-H5) specifically expressed in testis germinal cells FEBS Lett. 434 1998 289 294
    • (1998) FEBS Lett. , vol.434 , pp. 289-294
    • Munier, A.1
  • 32
    • 0141854009 scopus 로고    scopus 로고
    • The human transcriptome map reveals extremes in gene density, intron length, GC content, and repeat pattern for domains of highly and weakly expressed genes
    • R. Versteeg The human transcriptome map reveals extremes in gene density, intron length, GC content, and repeat pattern for domains of highly and weakly expressed genes Genome Res. 13 2003 1998 2004
    • (2003) Genome Res. , vol.13 , pp. 1998-2004
    • Versteeg, R.1
  • 33
    • 0035846451 scopus 로고    scopus 로고
    • Human endothelin converting enzyme-2 (ECE2): Characterization of mRNA species and chromosomal localization
    • M.-N. Lorenzo Human endothelin converting enzyme-2 (ECE2): characterization of mRNA species and chromosomal localization Biochim. Biophys. Acta 1522 2001 46 52
    • (2001) Biochim. Biophys. Acta , vol.1522 , pp. 46-52
    • Lorenzo, M.-N.1
  • 34
    • 0034306769 scopus 로고    scopus 로고
    • Molecular cloning of ring finger protein 21 (RNF21)/interferon-responsive finger protein (ifp1), which possesses two RING-B box-coiled coil domains in tandem
    • A. Orimo Molecular cloning of ring finger protein 21 (RNF21)/interferon- responsive finger protein (ifp1), which possesses two RING-B box-coiled coil domains in tandem Genomics 69 2000 143 149
    • (2000) Genomics , vol.69 , pp. 143-149
    • Orimo, A.1
  • 35
    • 0033664237 scopus 로고    scopus 로고
    • Fusion of the human gene for the polyubiquitination coeffector UVE1 with Kua, a newly identified gene
    • T. Thomsom Fusion of the human gene for the polyubiquitination coeffector UVE1 with Kua, a newly identified gene Genome Res. 10 2000 1743 1756
    • (2000) Genome Res. , vol.10 , pp. 1743-1756
    • Thomsom, T.1
  • 36
    • 0034812788 scopus 로고    scopus 로고
    • The paralemmin protein family: Identification of paralemmin-2, an isoform differentially spliced to AKAP2/AKAP-KL, and of palmdelphin, a more distant cytosolic relative
    • B. Hu, N.G. Copeland, D.J. Gilbert, N.A. Jenkins, and M.W. Kilimann The paralemmin protein family: identification of paralemmin-2, an isoform differentially spliced to AKAP2/AKAP-KL, and of palmdelphin, a more distant cytosolic relative Biochem. Biophys. Res. Commun. 285 2001 1369 1376
    • (2001) Biochem. Biophys. Res. Commun. , vol.285 , pp. 1369-1376
    • Hu, B.1    Copeland, N.G.2    Gilbert, D.J.3    Jenkins, N.A.4    Kilimann, M.W.5
  • 37
    • 0036847318 scopus 로고    scopus 로고
    • An endogenous hybrid mRNA encodes TWE-PRIL, a functional cell surface TWEAK-APRIL fusion protein
    • B. Pradet-Balade An endogenous hybrid mRNA encodes TWE-PRIL, a functional cell surface TWEAK-APRIL fusion protein EMBO J. 21 2002 5711 5720
    • (2002) EMBO J. , vol.21 , pp. 5711-5720
    • Pradet-Balade, B.1
  • 38
    • 0040962391 scopus 로고    scopus 로고
    • Identification of a general transcription factor TFIIAalpha/beta homolog selectively expressed in testis
    • A.B. Upadhyaya, S.H. Lee, and J. DeJong Identification of a general transcription factor TFIIAalpha/beta homolog selectively expressed in testis Biol. Chem. 274 1999 18040 18048
    • (1999) Biol. Chem. , vol.274 , pp. 18040-18048
    • Upadhyaya, A.B.1    Lee, S.H.2    Dejong, J.3
  • 39
    • 0346732315 scopus 로고    scopus 로고
    • Gene fusion and overlapping reading frames in the mammalian genes for 4E-BP3 and MASK
    • F. Poulin, A. Brueschke, and N. Sonenberg Gene fusion and overlapping reading frames in the mammalian genes for 4E-BP3 and MASK J. Biol. Chem. 278 2003 52290 52297
    • (2003) J. Biol. Chem. , vol.278 , pp. 52290-52297
    • Poulin, F.1    Brueschke, A.2    Sonenberg, N.3
  • 40
    • 0141706658 scopus 로고    scopus 로고
    • Hodgkin's lymphoma cell lines express a fusion protein encoded by intergenically spliced mRNA for the multilectin receptor DEC-205 (CD205) and a novel C-type lectin receptor DCL-1
    • M. Kato Hodgkin's lymphoma cell lines express a fusion protein encoded by intergenically spliced mRNA for the multilectin receptor DEC-205 (CD205) and a novel C-type lectin receptor DCL-1 J. Biol. Chem. 278 2003 34035 34041
    • (2003) J. Biol. Chem. , vol.278 , pp. 34035-34041
    • Kato, M.1
  • 41
    • 0037083393 scopus 로고    scopus 로고
    • Crystal structure of human nucleoside diphosphate kinase A, a metastatic suppressor
    • K. Min Crystal structure of human nucleoside diphosphate kinase A, a metastatic suppressor Proteins 46 2002 340 342
    • (2002) Proteins , vol.46 , pp. 340-342
    • Min, K.1
  • 42
    • 0026727881 scopus 로고
    • X-ray structure of nucleoside diphosphate kinase
    • C. Dumas X-ray structure of nucleoside diphosphate kinase EMBO J. 11 1992 3203 3208
    • (1992) EMBO J. , vol.11 , pp. 3203-3208
    • Dumas, C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.