Inhibition by a selective IκB kinase-2 inhibitor of interleukin-1-induced collagen degradation by corneal fibroblasts in three-dimensional culture

Investigative Ophthalmology and Visual Science

Volumn 49, Issue 11, 2008, Pages 4850-4857

  Kondo, Yukiko ^a   Fukuda, Ken ^a   Adachi, Tadafumi ^a   Nishida, Teruo ^a  

^a YAMAGUCHI UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

[5 (4 FLUOROPHENYL) 2 UREIDO]THIOPHENE 3 CARBOXAMIDE; COLLAGEN GEL; DEXAMETHASONE; GELATINASE A; GELATINASE B; HYDROXYPROLINE; I KAPPA B ALPHA; I KAPPA B KINASE INHIBITOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERSTITIAL COLLAGENASE; MESSENGER RNA; STROMELYSIN; UNCLASSIFIED DRUG; 2 ((AMINOCARBONYL)AMINO) 5 (4 FLUOROPHENYL) 3 THIOPHENECARBOXAMIDE; 2-((AMINOCARBONYL)AMINO)-5-(4-FLUOROPHENYL)-3-THIOPHENECARBOXAMIDE; AMIDE; COLLAGEN TYPE 1; I KAPPA B KINASE; THIOPHENE DERIVATIVE;

ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; CELLULAR DISTRIBUTION; COLLAGEN DEGRADATION; CONTROLLED STUDY; CORNEA; CORNEA ULCER; ENZYME ACTIVATION; FIBROBLAST; HYDROLYSIS; IMMUNOBLOTTING; IMMUNOFLUORESCENCE; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; RABBIT; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPECTROPHOTOMETRY; ZYMOGRAPHY; ANIMAL; BIOSYNTHESIS; CELL CULTURE; COMPARATIVE STUDY; DISEASE MODEL; DRUG ANTAGONISM; DRUG EFFECT; FLUORESCENCE MICROSCOPY; GENE EXPRESSION; GENETICS; IMMUNOHISTOCHEMISTRY; METABOLISM; PATHOLOGY;

AMIDES; ANIMALS; CELLS, CULTURED; COLLAGEN TYPE I; CORNEA; CORNEAL ULCER; DISEASE MODELS, ANIMAL; FIBROBLASTS; GENE EXPRESSION; I-KAPPA B KINASE; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; INTERLEUKIN-1BETA; MALE; MATRIX METALLOPROTEINASE 1; MATRIX METALLOPROTEINASE 3; MATRIX METALLOPROTEINASE 9; MICROSCOPY, FLUORESCENCE; RABBITS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SPECTROPHOTOMETRY; THIOPHENES;

EID: 55749102169     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.08-1897     Document Type: Article

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