Anti-fibroblast antibodies detected by cell-based ELISA in systemic sclerosis enhance the collagenolytic activity and matrix metalloproteinase-1 production in dermal fibroblasts

Rheumatology

Volumn 46, Issue 12, 2007, Pages 1779-1785

  Fineschi, S ^a   Cozzi, F ^b   Burger, D ^a   Dayer, J M ^a   Meroni, P L ^c   Chizzolini, C ^a,d  

^a University Hospital and Faculty of Medicine   (Switzerland)

^b UNIVERSITY HOSPITAL OF PADOVA   (Italy)

^c UNIVERSITY OF MILAN   (Italy)

^d GENEVA UNIVERSITY HOSPITALS   (Switzerland)

Author keywords

Anti fibroblast antibodies; Collagen; Fibrosis; Matrix metalloproteinase; Smad2 3

Indexed keywords

AUTOANTIBODY; AZATHIOPRINE; COLLAGEN; COLLAGEN TYPE 1; CYCLOPHOSPHAMIDE; DNA TOPOISOMERASE; FIBROBLAST ANTIBODY; ILOPROST; IMMUNOGLOBULIN G; INTERLEUKIN 1; INTERSTITIAL COLLAGENASE; MESSENGER RNA; METHOTREXATE; MONOCLONAL ANTIBODY; PENICILLAMINE; PREDNISONE; SMAD2 PROTEIN; SMAD3 PROTEIN; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG;

ADULT; ANTIBODY DETECTION; ANTIGEN BINDING; ARTICLE; CELL STIMULATION; CLINICAL ARTICLE; COLLAGEN DEGRADATION; CONTROLLED STUDY; CORRELATION ANALYSIS; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME SYNTHESIS; EXTRACELLULAR MATRIX; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOFLUORESCENCE; MALE; PLASMAPHERESIS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN PURIFICATION; SIGNAL TRANSDUCTION; SKIN BIOPSY; SKIN FIBROBLAST; STEADY STATE; SYSTEMIC SCLEROSIS; WESTERN BLOTTING;

ADULT; ANTIBODIES, ANTI-IDIOTYPIC; BLOTTING, WESTERN; CASE-CONTROL STUDIES; CELLS, CULTURED; COLLAGEN; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FIBROBLASTS; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; HUMANS; IMMUNOGLOBULIN G; INTERLEUKIN-1; MALE; MATRIX METALLOPROTEINASE 1; MIDDLE AGED; RNA, MESSENGER; SCLERODERMA, SYSTEMIC; SKIN; TISSUE INHIBITOR OF METALLOPROTEINASE-1;

EID: 36448974512     PISSN: 14620324     EISSN: 14620332     Source Type: Journal    
DOI: 10.1093/rheumatology/kem241     Document Type: Article

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