Stimulation of MAPK-phosphatase 1 gene expression by glucocorticoids occurs through a tethering mechanism involving C/EBP

Journal of Molecular Endocrinology

Volumn 41, Issue 3-4, 2008, Pages 239-249

  Johnasson Haque, Krishan ^a   Palanichamy, Elanchelian ^a   Okret, Sam ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

CCAAT ENHANCER BINDING PROTEIN BETA; GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE PHOSPHATASE 1;

ARTICLE; BINDING SITE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; ENZYME ACTIVATION; GEL MOBILITY SHIFT ASSAY; GENE EXPRESSION REGULATION; GENE INTERACTION; GENE LOCATION; GENE LOSS; HORMONE RECEPTOR INTERACTION; HUMAN; HUMAN CELL; IN VIVO STUDY; MOLECULAR DYNAMICS; MUTATIONAL ANALYSIS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; STRUCTURE ANALYSIS; TRANSACTIVATION; TRANSCRIPTION INITIATION SITE;

CCAAT-ENHANCER-BINDING PROTEINS; CELL LINE; CELL LINE, TUMOR; CHROMATIN IMMUNOPRECIPITATION; ELECTROPHORETIC MOBILITY SHIFT ASSAY; GENE EXPRESSION; GLUCOCORTICOIDS; HUMANS; MITOGEN-ACTIVATED PROTEIN KINASE 1; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; RECEPTORS, GLUCOCORTICOID; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 55749085407     PISSN: 09525041     EISSN: None     Source Type: Journal    
DOI: 10.1677/JME-08-0015     Document Type: Article

References (38)

1. Abraham SM, Lawrence T, Kleiman A, Warden P, Medghalchi M, Tuckermann J, Saklatvala J & Clark AR 2006 Antiinflammatory effects of dexamethasone are partly dependent on induction of dual specificity phosphatase 1. Journal of Experimental Medicine 203 1883-1889.
2. Adcock IM & Caramori G 2001 Cross-talk between pro-inflammatory transcription factors and glucocorticoids. Immunology and Cell Biology 79 376-384.
3. Alheim Y, Corness J, Samuelsson MK, Bladh LG, Murata T, Nilsson T & Okret S 2003 Identification of a functional glucocorticoid response element in the promoter of the cyclin-dependent kinase inhibitor p57Yip2. Journal of Molecular Endocrinology 30 359-368.
4. Bladh LG, Lidén J, Dahlman-Wright K, Reimers M, Nilsson S & Okret S 2005 Identification of endogenous glucocorticoid repressed genes differentially regulated by a glucocorticoid receptor mutant able to separate between nuclear factor-κB and activator protein-1 repression. Molecular Pharmacology 67 815-826.
5. Boruk M, Savory JC, & Haché RJ 1998 AF-2-dependent potentiation of CCAAT enhancer binding protein beta-mediated transcriptional activation by glucocorticoid receptor. Molecular Endocrinology 12 1749-1763.
6. Camps M, Nichols A & Arkinstall S 2000 Dual specificity phosphatases: a gene family for control of MAP kinase function. FASEB Journal 14 6-16.
7. Cassel TN, Nordlund-Möller L, Andersson O, Gustafsson JÅ & Nord M 2000 C/EBPα and C/EBPδ activate the clara cell secretory protein gene through interaction with two adjacent C/ EBP-binding sites. American Journal of Respiratory Cell and Molecular Biology 22 469-480.
8. Chang L & Karin M 2001 Mammalian MAP kinase signalling cascades. Nature 410 37-40.
9. Chen P, Li J, Barnes J, Kokkonen GC, Lee JC & Liu Y 2002 Restraint of proinflammatory cytokine biosynthesis by mitogen-activated protein kinase phosphatase-1 in lipopolysaccharide-stimulated macrophages. Journal of Immunology 169 6408-6416.
10. Clark AR 2007 Anti-inflammatory functions of glucocorticoid-induced genes. Molecular and Cellular Endocrinology 275 79-97.
11. Clark AR & Lasa M 2003 Crosstalk between glucocorticoids and mitogen-activated protein kinase signalling pathways. Current Opinion in Pharmacology 3 404-411.
12. Cram EJ, Ramos RA, Wang EC, Cha HH, Nishio Y & Firestone GL 1998 Role of the CCAAT/enhancer binding protein-alpha transcription factor in the glucocorticoid stimulation of p2lwafl/cipl gene promoter activity in growth-arrested rat hepatoma cells. Journal of Biological Chemistry 273 2008-2014.
13. Engelbrecht Y, de Wet H, Horsch K, Langeveldt CR, Hough FS & Hulley PA 2003 Glucocorticoids induce rapid up-regulation of mitogen-activated protein kinase phosphatase-1 and dephosphorylation of extracellular signal-regulated kinase and impair proliferation in human and mouse osteoblast cell lines. Endocrinology 144 412-422.
14. Greenbaum LE, Li W, Cressman DE, Peng Y, Ciliberto G, Poli V & Taub R 1998 CCAAT enhancer- binding protein beta is required for normal hepatocyte proliferation in mice after partial hepatectomy. Journal of Clinical Investigation 102 996-1007.
15. Horsch K, de Wet H, Schuurmans MM, Allie-Reid F, Cato AC, Cunningham J, Burrin JM, Hough FS & Holley PA 2007 Mitogen-activated protein kinase phosphatase 1/dual specificity phosphatase 1 mediates glucocorticoid inhibition of ostcoblast proliferation. Molecular Endocrinology 21 2929-2940.
16. Kassel O, Sancono A, Kratzschmar J, Kreft B, Stassen M & Cato AC 2001 Glucocorticoids inhibit MAP kinase via increased expression and decreased degradation of MKP-1. EMBO Journal 20 7108-7116.
17. Kushner PJ, Agard DA, Greene GL, Scanlan TS, Shiau AK, Uht RM & Webb P 2000 Estrogen receptor pathways to AP-1. Journal of Steroid Biochemistry and Molecular Biology 74 311-317.
18. Lasa M, Abraham SM, Boucheron C, Saklatvala J & Clark AR 2002 Dexamethasone causes sustained expression of mitogen-activated protein kinase (MAPK) phosphatase 1 and phosphatase-mediated inhibition of MAPK p38. Molecular and Cellular Biology 22 7802-7811.
19. Lidén J, Delaunay F, Rafter I, Gustafsson JÅ & Okret S 1997 A new function for the C-terminal zinc finger of the glucocorticoid receptor. Repression of RelA transactivation. Journal of Biological Chemistry 272 21467-21472.
20. Maier JV, Brema S, Tuckermann J, Herzer U, Klein M, Stassen M, Moorthy A & Cato AC 2007 Dual specificity phosphatase 1 knockout mice show enhanced susceptibility to anaphylaxis but are sensitive to glucocorticoids. Molecular Endocrinology 21 2663-2671.
21. Necela BM & Cidlowski JA 2004 Mechanisms of glucocorticoid receptor action in noninflammatory and inflammatory cells. Proceedings of the American Thoracic Society 1 239-246.
22. Noguchi T, Metz R, Chen L, Mattei MG, Carrasco D & Bravo R 1993 Structure, mapping, and expression of erp, a growth factor-inducible gene encoding a nontransmembrane protein tyrosine phosphatase, and effect of ERP on cell growth. Molecular and Cellular Biology 13 5195-5205.
23. Okret S, Wikström AC, Wrange Ö, Andersson B & Gustafsson JÅ 1984 Monoclonal antibodies against the rat liver glucocorticoid receptor. PNAS 81 1609-1613.
24. Owen GI, Richcr JK, Tung L, Takimoto G & Horwitz KB 1998 Progesterone regulates transcription of the p21 (WAF1) cyclin-dependent kinase inhibitor gene through Sp1 and CBP/p300. Journal of Biological Chemistry 273 10696-10701.
25. Pearson G, Robinson F, Beers Gibson T, Xu BE, Karandikar M, Berman K & Cobb MH 2001 Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions. Endocrine Reviews 22 153-183.
26. Phuc Le P, Friedman JR, Schug J, Brestelli JE, Parker JB, Bochkis IM & Kaestner KH 2005 Glucocorticoid receptor-dependent gene regulatory networks. PLoS Genetics 1 e16.
27. Rogatsky I, Wang JC, Derynck ME, Nonaka DF, Khodabakhsh DB, Haqq CM, Darimont BD, Garabedian MJ & Yamamoto KR 2003 Target-specific utilization of transcriptional regulatory surfaces by the glucocorticoid receptor. PNAS 100 13845-13850.
28. Schäcke H, Rehwinkel H, Asadullah K & Cato AC 2006 Insight into the molecular mechanisms of glucocorticoid receptor action promotes identification of novel ligands with an improved therapeutic index. Experimental Dermatology 15 565-573.
29. Serhan CN, Brain SD, Buckley CD, Gilroy DW, Haslett C, O'Neill LA, Perretti M, Rossi AG & Wallace JL 2007 Resolution of inflammation: state of the art, definitions and terms. FASEB Journal 21 325-332.
30. So AY, Chaivorapol C, Bolton EC, Li H & Yamamoto KR 2007 Determinants of cell- and gene-specific transcriptional regulation by the glucocorticoid receptor. PLoS Genetics 3 e94.
31. Stöcklin E, Wissler M, Gouilleux F & Groner B 1996 Functional interactions between Stat5 and the glucocor-ticoid receptor. Nature 383 726-728.
32. Subramaniam N, Campión J, Rafter I & Okret S 2003 Cross-talk between glucocorticoid and retinoic acid signals involving glucocorticoid receptor interaction with the homoeodomain protein Pbx1. Biochemical Journal 370 1087-1095.
33. Sun G, Porter W & Safe S 1998 Estrogen-induced retinoic acid receptor alpha 1 gene expression: role of estrogen receptor-Sp1 complex. Molecular Endocrinology 12 882-890.
34. Teurich S & Angel P 1995 The glucocorticoid receptor synergizes with Jun homodimers to activate AP-1-regulated promoters lacking GR binding sites. Chemical Senses 20 251-255.
35. Theodosiou A & Ashworth A 2002 MAP kinase phosphatases. Genome Biology 3 REVIEWS3009.
36. Tsai SY, Carlstedt-Duke J, Weigel NL, Dahlman Y, Gustafsson JÅ, Tsai Mj & O'Malley BW 1988 Molecular interactions of steroid hormone receptor with its enhancer element: evidence for receptor dimer formation. Cell 55 361-369.
37. Wu W, Pew T, Zou M, Pang D & Conzen SD 2005 Glucocorticoid receptor-induced MAPK phosphatase-1 (MPK-1) expression inhibits paclitaxel-associated MAPK activation and contributes to breast cancer cell survival. Journal of Biological Chemistry 280 4117-4124.
38. Zhao Q, Shepherd EG, Manson ME, Nelin LD, Sorokin A & Liu Y 2005 The role of mitogen-activated protein kinase phosphatase-1 in the response of alveolar macrophages to lipopolysaccharide: attenuation of proinflammatory cytokine biosynthesis via feedback control of p38. Journal of Biological Chemistry 280 8101-8108.