Phorbol 12-myristate 13-acetate (PMA) responsive sequence in G?q promoter during megakaryocytic differentiation Regulation by EGR-1 and MAP kinase pathway

Thrombosis and Haemostasis

Volumn 100, Issue 5, 2008, Pages 821-828

  Jalagadugula, Gauthami ^a   Dhanasekaran, Danny N ^a   Rao, A Koneti ^a  

^a TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

EGR 1; G q; MAP kinase; Megakaryocytic differentiation; PMA responsive sequence

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; EARLY GROWTH RESPONSE FACTOR 1; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; LUCIFERASE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; PHORBOL 13 ACETATE 12 MYRISTATE;

ACUTE MEGAKARYOCYTIC LEUKEMIA; ARTICLE; CELL DIFFERENTIATION; CELL TRANSFORMATION; CONTROLLED STUDY; DRUG EFFECT; DRUG INHIBITION; DRUG RESPONSE; ERYTHROLEUKEMIA CELL; GENE DELETION; GENE SEQUENCE; GENE SILENCING; HUMAN; HUMAN CELL; INHIBITION KINETICS; MEGAKARYOCYTE; NUCLEOTIDE SEQUENCE; OLIGONUCLEOTIDE PROBE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN SYNTHESIS INHIBITION; RECEPTOR UPREGULATION; REPORTER GENE; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; UPREGULATION;

5' FLANKING REGION; CELL DIFFERENTIATION; CELL LINE, TUMOR; EARLY GROWTH RESPONSE PROTEIN 1; ELECTROPHORETIC MOBILITY SHIFT ASSAY; GENES, REPORTER; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; HUMANS; MEGAKARYOCYTES; MITOGEN-ACTIVATED PROTEIN KINASES; OLIGONUCLEOTIDES, ANTISENSE; PROTEIN KINASE INHIBITORS; RESPONSE ELEMENTS; SIGNAL TRANSDUCTION; TETRADECANOYLPHORBOL ACETATE; UP-REGULATION;

EID: 55549143361     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1160/TH08-07-0496     Document Type: Article

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