MAP kinases: From intracellular signals to physiology and disease

News in Physiological Sciences

Volumn 17, Issue 2, 2002, Pages 62-67

  Schramek, Herbert ^a  

^a UNIVERSITY OF INNSBRUCK   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN D; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 2; MYOSIN HEAVY CHAIN; SYNAPTOPHYSIN;

ANGIOGENESIS; ARTICLE; CANCER; CARCINOGENESIS; CELL DIFFERENTIATION; CELL GROWTH; CELL MIGRATION; CELL PROLIFERATION; CELL SPECIFICITY; CELL SURVIVAL; CELL TRANSFORMATION; CELL TYPE; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; FIBROGENESIS; HEART VENTRICLE HYPERTROPHY; HUMAN; INFLAMMATION; METASTASIS; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION; VASCULAR ENDOTHELIUM; WOUND HEALING;

EID: 0036544842     PISSN: 08861714     EISSN: None     Source Type: Journal    
DOI: 10.1152/nips.01365.2001     Document Type: Article

References (15)

1. Two co-existing mechanisms for nuclear import of MAP kinase: Passive diffusion of a monomer and active transport of a dimer
2. Signaling angiogenesis via p42/p44 MAP kinase and hypoxia
3. Activation of extracellular signal-regulated kinase in proliferative glomerulonephritis in rats
4. The MEK1-ERK1/2 signaling pathway promotes compensated cardiac hypertrophy in transgenic mice
5. Integrin αvβ3 requirement for sustained mitogen-activated protein kinase activity during angiogenesis
6. Embryonic death of Mek1-deficient mice reveals a role for this kinase in angiogenesis in the labyrinthine region of the placenta
7. Phosphorylation of the MAP kinase ERK2 promotes its homodimerization and nuclear translocation
8. Differential expression of cell-cell adhesion proteins and cyclin D in MEK1-transdifferentiated MDCK cells
9. Constitutively active mitogen-activated protein kinase kinase MEK1 disrupts morphogenesis and induces an invasive phenotype in Madin-Darby Canine Kidney epithelial cells
10. Mitogen-activated protein kinases p42mapk and p44mapk are required for fibroblast proliferation
11. Integrating the MAP kinase signal into the G1 phase cell cycle machinery
12. Constitutively active mutant of the mitogen-activated protein kinase kinase MEK1 induces epithelial dedifferentiation and growth inhibition in Madin-Darby canine kidney cells
13. Differential long-term regulation of MEK and of p 42 MAPK in rat glomerular mesangial cells
14. Blockade of the MAP kinase pathway suppresses growth of colon tumors in vivo
15. TAK1 is activated in the myocardium after pressure overload and is sufficient to provoke heart failure in transgenic mice