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Volumn 19, Issue 9, 2008, Pages 3812-3822

RNA-binding protein HuR interacts with thrombomodulin 5′untranslated region and represses internal ribosome entry site-mediated translation under IL-1β treatment

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 1BETA; RNA BINDING PROTEIN; RNA BINDING PROTEIN HUR; THROMBOMODULIN; THROMBOMODULIN 5; UNCLASSIFIED DRUG;

EID: 55549131174     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.E07-09-0962     Document Type: Article
Times cited : (37)

References (48)
  • 1
    • 20944436774 scopus 로고    scopus 로고
    • The N-terminal domain of thrombomodulin sequesters high-mobility group-B1 protein, a novel antiinflammatory mechanism
    • Abeyama, K. et al. (2005). The N-terminal domain of thrombomodulin sequesters high-mobility group-B1 protein, a novel antiinflammatory mechanism. J. Clin. Invest. 115, 1267-1274.
    • (2005) J. Clin. Invest , vol.115 , pp. 1267-1274
    • Abeyama, K.1
  • 2
    • 0025967559 scopus 로고
    • Heterogeneous regulation of constitutive thrombomodulin or inducible tissue-factor activities on the surface of human saphenous-vein endothelial cells in culture following stimulation by interleukin-1, tumour necrosis factor, thrombin or phorbol ester
    • Archipoff, G., Beretz, A., Freyssinet, J. M., Klein-Soyer, C., Brisson, C., and Cazenave, J. P. (1991). Heterogeneous regulation of constitutive thrombomodulin or inducible tissue-factor activities on the surface of human saphenous-vein endothelial cells in culture following stimulation by interleukin-1, tumour necrosis factor, thrombin or phorbol ester. Biochem. J. 273, 679-684.
    • (1991) Biochem. J , vol.273 , pp. 679-684
    • Archipoff, G.1    Beretz, A.2    Freyssinet, J.M.3    Klein-Soyer, C.4    Brisson, C.5    Cazenave, J.P.6
  • 3
    • 0141889091 scopus 로고    scopus 로고
    • Regulation of eotaxin gene expression by TNF-alpha and IL-4 through mRNA stabilization: Involvement of the RNA-binding protein HuR
    • Atasoy, U., Curry, S. L., Lopez de Silanes, I., Shyu, A. B., Casolaro, V., Gorospe, M., and Stellato, C. (2003). Regulation of eotaxin gene expression by TNF-alpha and IL-4 through mRNA stabilization: involvement of the RNA-binding protein HuR. J. Immunol. 171, 4369-4378.
    • (2003) J. Immunol , vol.171 , pp. 4369-4378
    • Atasoy, U.1    Curry, S.L.2    Lopez de Silanes, I.3    Shyu, A.B.4    Casolaro, V.5    Gorospe, M.6    Stellato, C.7
  • 6
    • 0036191244 scopus 로고    scopus 로고
    • Inactivation of C3a and C5a octapeptides by carboxypeptidase R and carboxypeptidase N
    • Campbell, W. D., Lazoura, E., Okada, N., and Okada, H. (2002). Inactivation of C3a and C5a octapeptides by carboxypeptidase R and carboxypeptidase N. Microbiol. Immunol. 46, 131-134.
    • (2002) Microbiol. Immunol , vol.46 , pp. 131-134
    • Campbell, W.D.1    Lazoura, E.2    Okada, N.3    Okada, H.4
  • 7
    • 0023755932 scopus 로고
    • Tumor necrosis factor suppresses transcription of the thrombomodulin gene in endothelial cells
    • Conway, E. M., and Rosenberg, R. D. (1988). Tumor necrosis factor suppresses transcription of the thrombomodulin gene in endothelial cells. Mol. Cell. Biol. 8, 5588-5592.
    • (1988) Mol. Cell. Biol , vol.8 , pp. 5588-5592
    • Conway, E.M.1    Rosenberg, R.D.2
  • 8
    • 0036719075 scopus 로고    scopus 로고
    • The lectin-like domain of thrombomodulin confers protection from neutrophil-mediated tissue damage by suppressing adhesion molecule expression via nuclear factor kappaB and mitogen-activated protein kinase pathways
    • Conway, E. M. et al. (2002). The lectin-like domain of thrombomodulin confers protection from neutrophil-mediated tissue damage by suppressing adhesion molecule expression via nuclear factor kappaB and mitogen-activated protein kinase pathways. J. Exp. Med. 196, 565-577.
    • (2002) J. Exp. Med , vol.196 , pp. 565-577
    • Conway, E.M.1
  • 10
    • 0025174705 scopus 로고
    • Structure and function of thrombomodulin: A natural anticoagulant
    • Dittman, W. A., and Majerus, P. W. (1990). Structure and function of thrombomodulin: a natural anticoagulant. Blood 75, 329-336.
    • (1990) Blood , vol.75 , pp. 329-336
    • Dittman, W.A.1    Majerus, P.W.2
  • 11
    • 0027161205 scopus 로고
    • Molecular events that control the protein C anticoagulant pathway
    • Esmon, C. T. (1993). Molecular events that control the protein C anticoagulant pathway. Thromb. Haemost. 70, 29-35.
    • (1993) Thromb. Haemost , vol.70 , pp. 29-35
    • Esmon, C.T.1
  • 12
    • 33644801469 scopus 로고    scopus 로고
    • The interactions between inflammation and coagulation
    • Esmon, C. T. (2005). The interactions between inflammation and coagulation. Br. J. Haematol. 131, 417-430.
    • (2005) Br. J. Haematol , vol.131 , pp. 417-430
    • Esmon, C.T.1
  • 15
    • 0032437667 scopus 로고    scopus 로고
    • Control of translation initiation in animals
    • Gray, N., and Wickens, M. (1998). Control of translation initiation in animals. Annu. Rev. Cell Dev. Biol. 14, 399-458.
    • (1998) Annu. Rev. Cell Dev. Biol , vol.14 , pp. 399-458
    • Gray, N.1    Wickens, M.2
  • 16
    • 0033016717 scopus 로고    scopus 로고
    • Correlation between protein and mRNA abundance in yeast
    • Gygi, S. P., Rochon, Y., Franza, B. R., and Aebersold, R. (1999). Correlation between protein and mRNA abundance in yeast. Mol. Cell. Biol. 19, 1720-1730.
    • (1999) Mol. Cell. Biol , vol.19 , pp. 1720-1730
    • Gygi, S.P.1    Rochon, Y.2    Franza, B.R.3    Aebersold, R.4
  • 17
    • 2542638533 scopus 로고    scopus 로고
    • Activated protein C in sepsis: Emerging insights regarding its mechanism of action and clinical effectiveness
    • Haley, M., Cui, X., Minneci, P. C., Deans, K. J., Natanson, C., and Eichacker, P. Q. (2004). Activated protein C in sepsis: emerging insights regarding its mechanism of action and clinical effectiveness. Curr. Opin. Infect. Dis. 17, 205-211.
    • (2004) Curr. Opin. Infect. Dis , vol.17 , pp. 205-211
    • Haley, M.1    Cui, X.2    Minneci, P.C.3    Deans, K.J.4    Natanson, C.5    Eichacker, P.Q.6
  • 18
    • 16644393476 scopus 로고    scopus 로고
    • Isolation of bona fide differentially expressed genes in the 18-hour sepsis liver by suppression subtractive hybridization
    • Hsieh, Y. C., Hsu, C., Yang, R. C., Lee, P. Y., Hsu, H. K., and Sun, Y. M. (2004). Isolation of bona fide differentially expressed genes in the 18-hour sepsis liver by suppression subtractive hybridization. Shock 21, 549-555.
    • (2004) Shock , vol.21 , pp. 549-555
    • Hsieh, Y.C.1    Hsu, C.2    Yang, R.C.3    Lee, P.Y.4    Hsu, H.K.5    Sun, Y.M.6
  • 19
    • 0035805255 scopus 로고    scopus 로고
    • Integrated genomic and proteomic analyses of a systematically perturbed metabolic network
    • Ideker, T., Thorsson, V., and Ranish, J. A. (2001). Integrated genomic and proteomic analyses of a systematically perturbed metabolic network. Science 292, 929-934.
    • (2001) Science , vol.292 , pp. 929-934
    • Ideker, T.1    Thorsson, V.2    Ranish, J.A.3
  • 21
    • 0005218668 scopus 로고
    • Influences of mRNA secondary structure on initiation by eukaryotic ribosomes
    • Kozak, M. (1986). Influences of mRNA secondary structure on initiation by eukaryotic ribosomes. Proc. Natl. Acad. Sci. USA 83, 2850-2854.
    • (1986) Proc. Natl. Acad. Sci. USA , vol.83 , pp. 2850-2854
    • Kozak, M.1
  • 22
    • 0036894711 scopus 로고    scopus 로고
    • ELAV/Hu proteins inhibit p27 translation via an IRES element in the p27 5′UTR
    • Kullmann, M., Gopfert, U., Siewe, B., and Hengst, L. (2002). ELAV/Hu proteins inhibit p27 translation via an IRES element in the p27 5′UTR. Genes Dev. 16, 3087-3099.
    • (2002) Genes Dev , vol.16 , pp. 3087-3099
    • Kullmann, M.1    Gopfert, U.2    Siewe, B.3    Hengst, L.4
  • 23
    • 0037235585 scopus 로고    scopus 로고
    • Bacterial lipopolysaccharide decreases thrombomodulin expression in the sinusoidal endothelial cells of rats - a possible mechanism of intrasinusoidal microthrombus formation and liver dysfunction
    • Kume, M., Hayashi, T., Yuasa, H., Tanaka, H., Nishioka, J., Ido, M., Gabazza, E. C., Kawarada, Y., and Suzuki, K. (2003). Bacterial lipopolysaccharide decreases thrombomodulin expression in the sinusoidal endothelial cells of rats - a possible mechanism of intrasinusoidal microthrombus formation and liver dysfunction. J. Hepatol. 38, 9-17.
    • (2003) J. Hepatol , vol.38 , pp. 9-17
    • Kume, M.1    Hayashi, T.2    Yuasa, H.3    Tanaka, H.4    Nishioka, J.5    Ido, M.6    Gabazza, E.C.7    Kawarada, Y.8    Suzuki, K.9
  • 24
    • 0036000028 scopus 로고    scopus 로고
    • Hypoxia-inducibile factor-1 alpha mRNA contains an internal ribosome entry site that allows efficiency translation during normoxia and hypoxia
    • Lang, K. J., Kappel, A., and Goodall, G. J. (2002). Hypoxia-inducibile factor-1 alpha mRNA contains an internal ribosome entry site that allows efficiency translation during normoxia and hypoxia. Mol. Biol. Cell 13, 1792-1801.
    • (2002) Mol. Biol. Cell , vol.13 , pp. 1792-1801
    • Lang, K.J.1    Kappel, A.2    Goodall, G.J.3
  • 25
    • 0030797874 scopus 로고    scopus 로고
    • A common RNA structural motif involved in the internal initiation of translation of cellular mRNAs
    • Le, S. Y., and Maizel, J. V. (1997). A common RNA structural motif involved in the internal initiation of translation of cellular mRNAs. Nucl. Acid Res. 25, 362-369.
    • (1997) Nucl. Acid Res , vol.25 , pp. 362-369
    • Le, S.Y.1    Maizel, J.V.2
  • 26
    • 33748575589 scopus 로고    scopus 로고
    • Wnt-5a mRNA translation is suppressed by the Elav-like protein HuR in human breast epithelial cells
    • Leandersson, K., Riesbeck, K., and Andersson, T. (2006). Wnt-5a mRNA translation is suppressed by the Elav-like protein HuR in human breast epithelial cells. Nucleic Acids Res. 34, 3988-3999.
    • (2006) Nucleic Acids Res , vol.34 , pp. 3988-3999
    • Leandersson, K.1    Riesbeck, K.2    Andersson, T.3
  • 27
    • 0025963529 scopus 로고
    • Regulation of thrombomodulin by tumor necrosis factor-alpha: Comparison of transcriptional and posttranscriptional mechanisms
    • Lentz, S. R., Tsiang, M., and Sadler, J. E. (1991). Regulation of thrombomodulin by tumor necrosis factor-alpha: comparison of transcriptional and posttranscriptional mechanisms. Blood 77, 542-550.
    • (1991) Blood , vol.77 , pp. 542-550
    • Lentz, S.R.1    Tsiang, M.2    Sadler, J.E.3
  • 28
    • 26444440564 scopus 로고    scopus 로고
    • Two-way interactions between inflammation and coagulation
    • Levi, M., and Van der Poll, T. (2005). Two-way interactions between inflammation and coagulation. Trends Cardiovasc. Med. 15, 254-259.
    • (2005) Trends Cardiovasc. Med , vol.15 , pp. 254-259
    • Levi, M.1    Van der Poll, T.2
  • 29
    • 24144499990 scopus 로고    scopus 로고
    • Involvement of KSRP in the post-transcriptional regulation of human iNOS expression-complex interplay of KSRP with TTP and HuR
    • Linker, K., Pautz, A., Fechir, M., Hubrich, T., Greeve, J., and Kleinert, H. (2005). Involvement of KSRP in the post-transcriptional regulation of human iNOS expression-complex interplay of KSRP with TTP and HuR. Nucleic Acids Res. 33, 4813-4827.
    • (2005) Nucleic Acids Res , vol.33 , pp. 4813-4827
    • Linker, K.1    Pautz, A.2    Fechir, M.3    Hubrich, T.4    Greeve, J.5    Kleinert, H.6
  • 30
    • 0033591465 scopus 로고    scopus 로고
    • Expanded sequence dependence of thermodynamic parameters improves prediction of RNA secondary structure
    • Mathews, D. H., Sabina, J., Zuker, M., and Turner, D. H. (1999). Expanded sequence dependence of thermodynamic parameters improves prediction of RNA secondary structure. J. Mol. Biol. 288, 911-940.
    • (1999) J. Mol. Biol , vol.288 , pp. 911-940
    • Mathews, D.H.1    Sabina, J.2    Zuker, M.3    Turner, D.H.4
  • 31
    • 34447532192 scopus 로고    scopus 로고
    • Meisner, N. C. et al. (2007). Identification and mechanistic characterization of low-molecular-weight inhibitors for HuR. Nat. Chem. Biol. 3, 508-515.
    • Meisner, N. C. et al. (2007). Identification and mechanistic characterization of low-molecular-weight inhibitors for HuR. Nat. Chem. Biol. 3, 508-515.
  • 32
    • 20144386175 scopus 로고    scopus 로고
    • The ELAV RNA-stability factor HuR binds the 5′-untranslated region of the human IGF-IR transcript and differentially represses cap-dependent and IRES-mediated translation
    • Meng, Z., King, P. H., Nabors, L. B., Jackson, N. L., Chen, C. Y., Emanuel, P. D., and Blume, S. W. (2005). The ELAV RNA-stability factor HuR binds the 5′-untranslated region of the human IGF-IR transcript and differentially represses cap-dependent and IRES-mediated translation. Nucleic Acids Res. 33, 2962-2979.
    • (2005) Nucleic Acids Res , vol.33 , pp. 2962-2979
    • Meng, Z.1    King, P.H.2    Nabors, L.B.3    Jackson, N.L.4    Chen, C.Y.5    Emanuel, P.D.6    Blume, S.W.7
  • 33
    • 0023089665 scopus 로고
    • Endotoxin enhances tissue factor and suppresses thrombomodulin expression of human vascular endothelium in vitro
    • Moore, K. L., Andreoli, S. P., Esmon, N. L., Esmon, C. T., and Bang, N. U. (1987). Endotoxin enhances tissue factor and suppresses thrombomodulin expression of human vascular endothelium in vitro. J. Clin. Invest. 79, 124-130.
    • (1987) J. Clin. Invest , vol.79 , pp. 124-130
    • Moore, K.L.1    Andreoli, S.P.2    Esmon, N.L.3    Esmon, C.T.4    Bang, N.U.5
  • 34
    • 0024589205 scopus 로고
    • Tumor necrosis factor leads to the internalization and degradation of thrombomodulin from the surface of bovine aortic endothelial cells in culture
    • Moore, K. L., Esmon, C. T., and Esmon, N. L. (1989). Tumor necrosis factor leads to the internalization and degradation of thrombomodulin from the surface of bovine aortic endothelial cells in culture. Blood 73, 159-165.
    • (1989) Blood , vol.73 , pp. 159-165
    • Moore, K.L.1    Esmon, C.T.2    Esmon, N.L.3
  • 35
    • 0035707639 scopus 로고    scopus 로고
    • Regulation of inflammatory responses by natural anticoagulants
    • Okajima, K. (2001). Regulation of inflammatory responses by natural anticoagulants. Immunol. Rev. 184, 258-274.
    • (2001) Immunol. Rev , vol.184 , pp. 258-274
    • Okajima, K.1
  • 36
    • 0023720048 scopus 로고
    • Internal initiation of translation of eukaryotic mRNA directed by a sequence derived from poliovirus RNA
    • Pelletier, J., and Sonenberg, N. (1988). Internal initiation of translation of eukaryotic mRNA directed by a sequence derived from poliovirus RNA. Nature 334, 320-325.
    • (1988) Nature , vol.334 , pp. 320-325
    • Pelletier, J.1    Sonenberg, N.2
  • 37
    • 12344281782 scopus 로고    scopus 로고
    • The implications of structured 5′ untranslated regions on translation and disease
    • Pickering, B. M., and Willis, A. E. (2005). The implications of structured 5′ untranslated regions on translation and disease. Semin. Cell Dev. Biol. 16, 39-47.
    • (2005) Semin. Cell Dev. Biol , vol.16 , pp. 39-47
    • Pickering, B.M.1    Willis, A.E.2
  • 39
    • 33845654723 scopus 로고    scopus 로고
    • IL-10-induced TNF-alpha mRNA destabilization is mediated via IL-10 suppression of p38 MAP kinase activation and inhibition of HuR expression
    • Rajasingh, J., Bord, E., Luedemann, C., Asai, J., Hamada, H., Thorne, T., Qin, G., Goukassian, D., Zhu, Y., Losordo, D. W., and Kishore, R. (2006). IL-10-induced TNF-alpha mRNA destabilization is mediated via IL-10 suppression of p38 MAP kinase activation and inhibition of HuR expression. FASEB J. 20, 2112-2114.
    • (2006) FASEB J , vol.20 , pp. 2112-2114
    • Rajasingh, J.1    Bord, E.2    Luedemann, C.3    Asai, J.4    Hamada, H.5    Thorne, T.6    Qin, G.7    Goukassian, D.8    Zhu, Y.9    Losordo, D.W.10    Kishore, R.11
  • 40
    • 0032556949 scopus 로고    scopus 로고
    • c-Myc 5′ untranslated region contains an internal ribosome entry segment
    • Stoneley, M., Paulin, F. E., Le Quesne, J. P., Chappell, S. A., and Willis, A. E. (1998). c-Myc 5′ untranslated region contains an internal ribosome entry segment. Oncogene 16, 423-428.
    • (1998) Oncogene , vol.16 , pp. 423-428
    • Stoneley, M.1    Paulin, F.E.2    Le Quesne, J.P.3    Chappell, S.A.4    Willis, A.E.5
  • 41
    • 2342633872 scopus 로고    scopus 로고
    • Cellular internal ribosome entry segments: Structures, trans-acting factors and regulation of gene expression
    • Stoneley, M., and Willis, A. E. (2004). Cellular internal ribosome entry segments: structures, trans-acting factors and regulation of gene expression. Oncogene 23, 3200-3207.
    • (2004) Oncogene , vol.23 , pp. 3200-3207
    • Stoneley, M.1    Willis, A.E.2
  • 43
    • 2942705827 scopus 로고    scopus 로고
    • Novel functions of thrombomodulin in inflammation
    • Van de Wouwer, M., and Conway, E. M. (2004). Novel functions of thrombomodulin in inflammation. Crit. Care Med. 32, S254-S261.
    • (2004) Crit. Care Med , vol.32
    • Van de Wouwer, M.1    Conway, E.M.2
  • 45
    • 0028955936 scopus 로고
    • Alternative translation of human fibroblast growth factor 2 mRNA occurs by internal entry of ribosomes
    • Vanger, S., Gensac, M. C., Maret, A., Bayard, F., Amalric, F., Prats, H., and Prats, A. C. (1995). Alternative translation of human fibroblast growth factor 2 mRNA occurs by internal entry of ribosomes. Mol. Cell. Biol. 15, 35-44.
    • (1995) Mol. Cell. Biol , vol.15 , pp. 35-44
    • Vanger, S.1    Gensac, M.C.2    Maret, A.3    Bayard, F.4    Amalric, F.5    Prats, H.6    Prats, A.C.7
  • 47
    • 0018964280 scopus 로고
    • Sepsis and septic shock-a review of laboratory models and a proposal
    • Wichterman, K. A., Baue, A. E., and Chaudry, I. H. (1980). Sepsis and septic shock-a review of laboratory models and a proposal. J. Surg. Res. 29, 189-201.
    • (1980) J. Surg. Res , vol.29 , pp. 189-201
    • Wichterman, K.A.1    Baue, A.E.2    Chaudry, I.H.3
  • 48
    • 33746855405 scopus 로고    scopus 로고
    • The identification of an internal ribosomal entry site in the 5′-untranslated region of p53 mRNA provides a novel mechanism for the regulation of its translation following DNA damage
    • Yang, D. Q., Halaby, M. J., and Zhang, Y. (2006). The identification of an internal ribosomal entry site in the 5′-untranslated region of p53 mRNA provides a novel mechanism for the regulation of its translation following DNA damage. Oncogene 25, 4613-4619.
    • (2006) Oncogene , vol.25 , pp. 4613-4619
    • Yang, D.Q.1    Halaby, M.J.2    Zhang, Y.3


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