Bacterial lipopolysaccharide decreases thrombomodulin expression in the sinusoidal endothelial cells of rats - A possible mechanism of intrasinusoidal microthrombus formation and liver dysfunction

Journal of Hepatology

Volumn 38, Issue 1, 2003, Pages 9-17

  Kume, Masane ^a   Hayashi, Tatsuya ^a   Yuasa, Hiroyuki ^a   Tanaka, Hitoshi ^a   Nishioka, Junji ^a   Ido, Masaru ^a   Gabazza, Esteban C ^a   Kawarada, Yoshifumi ^a   Suzuki, Koji ^a  

^a MIE UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Sepsis; Sinusoidal endothelial cells; Thrombomodulin

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; FIBRIN DEGRADATION PRODUCT; MESSENGER RNA; RECOMBINANT THROMBOMODULIN; THROMBOMODULIN; TISSUE ANTIGEN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CELL DAMAGE; CELL ISOLATION; CONTROLLED STUDY; DRUG EFFICACY; ENDOTHELIUM CELL; ENDOTOXEMIA; ENZYME IMMUNOASSAY; FIBRIN DEPOSITION; IMMUNOHISTOCHEMISTRY; LIVER DYSFUNCTION; LIVER SINUSOID; MICROTHROMBUS; NONHUMAN; PATHOPHYSIOLOGY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; THROMBOGENESIS; TISSUE LEVEL;

ANIMALS; CYTOKINES; ENDOTHELIUM, VASCULAR; ESCHERICHIA COLI; IMMUNOHISTOCHEMISTRY; LIPOPOLYSACCHARIDES; LIVER CIRCULATION; LIVER DISEASES; RATS; RECOMBINANT PROTEINS; RNA; RNA, MESSENGER; THROMBOMODULIN; THROMBOSIS;

EID: 0037235585     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-8278(02)00324-0     Document Type: Article

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