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Volumn 130, Issue 44, 2008, Pages 14739-14744

Redox-triggered contents release from liposomes

Author keywords

[No Author keywords available]

Indexed keywords

AGGLOMERATION; AMPHIPHILES; ENZYME ACTIVITY; ENZYMES; HISTOLOGY; LIPIDS; PHOSPHOLIPIDS;

EID: 55549102682     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja8050469     Document Type: Article
Times cited : (176)

References (69)
  • 30
    • 55549107309 scopus 로고    scopus 로고
    • 3rd ed, Gregoriadis, G, Ed, CRC Press: Boca Raton, FL
    • Huang, Z.; Szoka, F. C. In Liposome Technology, 3rd ed.; Gregoriadis, G., Ed.; CRC Press: Boca Raton, FL, 2006; Vol. 3, pp 165-196.
    • (2006) Liposome Technology , vol.3 , pp. 165-196
    • Huang, Z.1    Szoka, F.C.2
  • 48
    • 55549098709 scopus 로고    scopus 로고
    • The following nomenclature will be adapted throughout the article: Q and HQ refer to the oxidized and reduced forms of the quinone, respectively, regardless of whether HQ is generated in situ (e.g., 1-HQ3) or synthesized (e.g., 3-HQ1). For instance, 1-HQ1 is the reduced form of 1-Q1.
    • The following nomenclature will be adapted throughout the article: "Q" and "HQ" refer to the oxidized and reduced forms of the quinone, respectively, regardless of whether "HQ" is generated in situ (e.g., 1-HQ3) or synthesized (e.g., 3-HQ1). For instance, 1-HQ1 is the reduced form of 1-Q1.
  • 61
    • 0033004706 scopus 로고    scopus 로고
    • Calcein is known to be quenched by Triton, and this quenching is Triton concentration dependent. See:, and references therein for more information on this topic
    • Calcein is known to be quenched by Triton, and this quenching is Triton concentration dependent. See: Memoli, A.; Palermiti, L. G.; Travagli, V.; Alhaique, F. J. Pharm. Biomed. Anal. 1999, 19, 627-632, and references therein for more information on this topic.
    • (1999) J. Pharm. Biomed. Anal , vol.19 , pp. 627-632
    • Memoli, A.1    Palermiti, L.G.2    Travagli, V.3    Alhaique, F.4
  • 62
    • 55549088700 scopus 로고    scopus 로고
    • 0 is the initial emission intensity.
    • 0 is the initial emission intensity.
  • 63
    • 55549123171 scopus 로고    scopus 로고
    • It is assumed here that the quinone units located in the outer layer of the liposomes are kinetically and equally accessible, such that probability of reduction of the liposomal lipids (1-Q1 and 1-Q3) can be approximated by the thermodynamic reduction potentials of the model quinones 2-Q1 and 2-Q3
    • It is assumed here that the quinone units located in the outer layer of the liposomes are kinetically and equally accessible, such that probability of reduction of the liposomal lipids (1-Q1 and 1-Q3) can be approximated by the thermodynamic reduction potentials of the model quinones (2-Q1 and 2-Q3).
  • 64
    • 0032573128 scopus 로고    scopus 로고
    • 4 is non-membrane-permeable and is therefore incapable of reducing the lipids located in the interior layer of the liposome. For instance, see: Angeletti, C.; Nichols, J. W. Biochemistry 1998, 37, 15114-15119.
    • 4 is non-membrane-permeable and is therefore incapable of reducing the lipids located in the interior layer of the liposome. For instance, see: Angeletti, C.; Nichols, J. W. Biochemistry 1998, 37, 15114-15119.
  • 66
    • 55549112035 scopus 로고    scopus 로고
    • Intraliposomal bilayer-bilayer contact in oligolamellar Q-DOPE liposomes may also contribute to liposome collapse and contents release. The mechanism of Q-DOPE liposome collapse is currently being investigated in detail
    • Intraliposomal bilayer-bilayer contact in oligolamellar Q-DOPE liposomes may also contribute to liposome collapse and contents release. The mechanism of Q-DOPE liposome collapse is currently being investigated in detail.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.