Development and validation of a novel bioreactor system for load- and perfusion-controlled tissue engineering of chondrocyte-constructs

Biotechnology and Bioengineering

Volumn 101, Issue 4, 2008, Pages 714-728

  Schulz, Ronny M ^a   Wüstneck, Nico ^a   Van Donkelaar, Corrinus C ^b   Shelton, Julia C ^c   Bader, Augustinus ^a  

^a UNIVERSITY OF LEIPZIG   (Germany)

^b EINDHOVEN UNIVERSITY OF TECHNOLOGY   (Netherlands)

^c QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

Biomedical engineering; Bioreactor; Cartilage; Chondrocytes; Physical stimulation; Tissue engineering

Indexed keywords

BIOCONVERSION; BIOMECHANICS; BIOMEDICAL ENGINEERING; BIOREACTORS; BODY FLUIDS; CARTILAGE; CELL CULTURE; COLLOIDS; ENGINEERING; FORESTRY; GELATION; INDUSTRIAL CHEMICALS; LIGAMENTS; LOADING; MAGNETIC FIELDS; MECHANICAL PROPERTIES; NUCLEIC ACIDS; ORGANIC ACIDS; PROXIMITY SENSORS; SCAFFOLDS; TISSUE;

AGAROSE; AGAROSE GELS; AGGRECAN; APPLIED MAGNETIC FIELDS; ARTICULAR CARTILAGES; AXIAL LOADINGS; BENEFICIAL EFFECTS; BIOREACTOR SYSTEMS; CALIBRATION PROCEDURES; CELL VIABILITIES; CHONDROCYTE; CHONDROCYTES; CONTACTLESS; CULTIVATION PROCEDURES; CULTURE DEVICES; CYCLIC MECHANICAL LOADINGS; DNA QUANTIFICATIONS; EXPERIMENTAL DATUMS; FOCAL CARTILAGE DEFECTS; IMMUNOSTAINING; LIVE/DEAD STAINING; LOAD CELLS; LOADING FREQUENCIES; LOADING SYSTEMS; MECHANICAL LOADINGS; OSTEO ARTHRITISES; PHYSICAL STIMULATION; PRECISE MEASUREMENTS; PROOF OF PRINCIPLES; REPRODUCIBILITY; SULFATED GLYCOSAMINOGLYCAN; TIME FEEDBACKS; TREATMENT MODALITIES;

TISSUE ENGINEERING;

AGAROSE; AGGRECAN; ALCIAN BLUE; GLYCOSAMINOGLYCAN POLYSULFATE;

ARTICLE; ARTICULAR CARTILAGE; BIOREACTOR; CARTILAGE CELL; CELL VIABILITY; FLOW RATE; FLUOROMETRY; HYDROGEL; IMMUNOHISTOCHEMISTRY; LOAD CARRYING CAPACITY; MAGNETIC FIELD; PERFUSION; SHEAR STRESS; STAINING; TISSUE ENGINEERING;

BIOREACTORS; CARTILAGE; CARTILAGE, ARTICULAR; CHONDROCYTES; EQUIPMENT DESIGN; MECHANOTRANSDUCTION, CELLULAR; TISSUE ENGINEERING;

EID: 55549090760     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.21955     Document Type: Article

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