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Volumn 15, Issue 10, 2008, Pages 1529-1535

Development of antibodies to PspA families 1 and 2 in children after exposure to Streptococcus pneumoniae

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; BACTERIAL PROTEIN; PNEUMOCOCCAL SURFACE PROTEIN A; UNCLASSIFIED DRUG; VIRULENCE FACTOR; BACTERIUM ANTIBODY; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G;

EID: 55449095065     PISSN: 15566811     EISSN: 1556679X     Source Type: Journal    
DOI: 10.1128/CVI.00181-08     Document Type: Article
Times cited : (22)

References (43)
  • 1
    • 0033984377 scopus 로고    scopus 로고
    • Intranasal immunization of mice with a mixture of the pneumococcal proteins PsaA and PspA is highly protective against nasopharyngeal carriage of Streptococcus pneumoniae
    • Briles, D. E., E. Ades, J. C. Paton, J. S. Sampson, G. M. Carlone, R. C. Huebner, A. Virolainen, E. Swiatlo, and S. K. Hollingshead. 2000. Intranasal immunization of mice with a mixture of the pneumococcal proteins PsaA and PspA is highly protective against nasopharyngeal carriage of Streptococcus pneumoniae. Infect. Immun. 68:796-800.
    • (2000) Infect. Immun , vol.68 , pp. 796-800
    • Briles, D.E.1    Ades, E.2    Paton, J.C.3    Sampson, J.S.4    Carlone, G.M.5    Huebner, R.C.6    Virolainen, A.7    Swiatlo, E.8    Hollingshead, S.K.9
  • 2
    • 0033680686 scopus 로고    scopus 로고
    • Immunization of humans with recombinant pneumococcal surface protein A (rPspA) elicits antibodies that passively protect mice from fatal infection with Streptococcus pneumoniae bearing heterologous PspA
    • Briles, D. E., S. K. Hollingshead, J. King, A. Swift, P. A. Braun, M. K. Park, L. M. Ferguson, M. H. Nahm, and G. S. Nabors. 2000. Immunization of humans with recombinant pneumococcal surface protein A (rPspA) elicits antibodies that passively protect mice from fatal infection with Streptococcus pneumoniae bearing heterologous PspA. J. Infect. Dis. 182:1694-1701.
    • (2000) J. Infect. Dis , vol.182 , pp. 1694-1701
    • Briles, D.E.1    Hollingshead, S.K.2    King, J.3    Swift, A.4    Braun, P.A.5    Park, M.K.6    Ferguson, L.M.7    Nahm, M.H.8    Nabors, G.S.9
  • 3
    • 0042665483 scopus 로고    scopus 로고
    • Briles, D. E., S. K. Hollingshead, J. C. Paton, E. W. Ades, L. Novak, F. W. van Ginkel, and W. H. Benjamin, Jr. 2003. Immunizations with pneumococcal surface protein A and pneumolysin are protective against pneumonia in a murine model of pulmonary infection with Streptococcus pneumoniae. J. Infect. Dis. 188:339-348.
    • Briles, D. E., S. K. Hollingshead, J. C. Paton, E. W. Ades, L. Novak, F. W. van Ginkel, and W. H. Benjamin, Jr. 2003. Immunizations with pneumococcal surface protein A and pneumolysin are protective against pneumonia in a murine model of pulmonary infection with Streptococcus pneumoniae. J. Infect. Dis. 188:339-348.
  • 6
    • 36749007140 scopus 로고    scopus 로고
    • Fusion proteins containing family 1 and family 2 PspA fragments elicit protection against Streptococcus pneumoniae that correlates with antibody-mediated enhancement of complement deposition
    • Darrieux, M., E. N. Miyaji, D. M. Ferreira, L. M. Lopes, A. P. Lopes, B. Ren, D. E. Briles, S. K. Hollingshead, and L. C. Leite. 2007. Fusion proteins containing family 1 and family 2 PspA fragments elicit protection against Streptococcus pneumoniae that correlates with antibody-mediated enhancement of complement deposition. Infect. Immun. 75:5930-5938.
    • (2007) Infect. Immun , vol.75 , pp. 5930-5938
    • Darrieux, M.1    Miyaji, E.N.2    Ferreira, D.M.3    Lopes, L.M.4    Lopes, A.P.5    Ren, B.6    Briles, D.E.7    Hollingshead, S.K.8    Leite, L.C.9
  • 7
    • 0019256014 scopus 로고    scopus 로고
    • Gray, B. M., G. M. Converse III, and H. C. Dillon, Jr. 1980. Epidemiologic studies of Streptococcus pneumoniae in infants: acquisition, carriage, and infection during the first 24 months of life. J. Infect. Dis. 142:923-933.
    • Gray, B. M., G. M. Converse III, and H. C. Dillon, Jr. 1980. Epidemiologic studies of Streptococcus pneumoniae in infants: acquisition, carriage, and infection during the first 24 months of life. J. Infect. Dis. 142:923-933.
  • 9
    • 0033003470 scopus 로고    scopus 로고
    • Identification of pneumococcal surface protein A as a lactoferrin-binding protein of Streptococcus pneumoniae
    • Hammerschmidt, S., G. Bethe, P. H. Remane, and G. S. Chhatwal. 1999. Identification of pneumococcal surface protein A as a lactoferrin-binding protein of Streptococcus pneumoniae. Infect. Immun. 67:1683-1687.
    • (1999) Infect. Immun , vol.67 , pp. 1683-1687
    • Hammerschmidt, S.1    Bethe, G.2    Remane, P.H.3    Chhatwal, G.S.4
  • 10
    • 0345689464 scopus 로고    scopus 로고
    • From nose to lung: The regulation behind Streptococcus pneumoniae virulence factors
    • Hava, D. L., J. LeMieux, and A. Camilli. 2003. From nose to lung: the regulation behind Streptococcus pneumoniae virulence factors. Mol. Microbiol. 50:1103-1110.
    • (2003) Mol. Microbiol , vol.50 , pp. 1103-1110
    • Hava, D.L.1    LeMieux, J.2    Camilli, A.3
  • 11
    • 32044457408 scopus 로고    scopus 로고
    • Pneumococcal surface protein A (PspA) family distribution among clinical isolates from adults over 50 years of age collected in seven countries
    • Hollingshead, S. K., L. Baril, S. Ferro, J. King, P. Coan, and D. E. Briles. 2006. Pneumococcal surface protein A (PspA) family distribution among clinical isolates from adults over 50 years of age collected in seven countries. J. Med. Microbiol. 55:215-221.
    • (2006) J. Med. Microbiol , vol.55 , pp. 215-221
    • Hollingshead, S.K.1    Baril, L.2    Ferro, S.3    King, J.4    Coan, P.5    Briles, D.E.6
  • 12
    • 0033801656 scopus 로고    scopus 로고
    • Diversity of PspA: Mosaic genes and evidence for past recombination in Streptococcus pneumoniae
    • Hollingshead, S. K., R. Becker, and D. E. Briles. 2000. Diversity of PspA: mosaic genes and evidence for past recombination in Streptococcus pneumoniae. Infect. Immun. 68:5889-5900.
    • (2000) Infect. Immun , vol.68 , pp. 5889-5900
    • Hollingshead, S.K.1    Becker, R.2    Briles, D.E.3
  • 13
    • 28344441389 scopus 로고    scopus 로고
    • Development of natural antibodies to pneumococcal surface protein A, pneumococcal surface adhesin A and pneumolysin in Filipino pregnant women and their infants in relation to pneumococcal carriage
    • Holmlund, E., B. Quiambao, J. Ollgren, H. Nohynek, and H. Kayhty. 2006. Development of natural antibodies to pneumococcal surface protein A, pneumococcal surface adhesin A and pneumolysin in Filipino pregnant women and their infants in relation to pneumococcal carriage. Vaccine 24:57-65.
    • (2006) Vaccine , vol.24 , pp. 57-65
    • Holmlund, E.1    Quiambao, B.2    Ollgren, J.3    Nohynek, H.4    Kayhty, H.5
  • 15
    • 0034934568 scopus 로고    scopus 로고
    • Bacteriology of acute otitis media in a cohort of Finnish children followed for the first two years of life
    • Kilpi, T., E. Herva, T. Kaijalainen, R. Syrjanen, and A. K. Takala. 2001. Bacteriology of acute otitis media in a cohort of Finnish children followed for the first two years of life. Pediatr. Infect. Dis. J. 20:654-662.
    • (2001) Pediatr. Infect. Dis. J , vol.20 , pp. 654-662
    • Kilpi, T.1    Herva, E.2    Kaijalainen, T.3    Syrjanen, R.4    Takala, A.K.5
  • 16
    • 2542585520 scopus 로고    scopus 로고
    • Age-specific immunoglobulin G (IgG) and IgA to pneumococcal protein antigens in a population in coastal
    • Laine, C., T. Mwangi, C. M. Thompson, J. Obiero, M. Lipsitch, and J. A. Scott. 2004. Age-specific immunoglobulin G (IgG) and IgA to pneumococcal protein antigens in a population in coastal Kenya. Infect. Immun. 72:3331-3335.
    • (2004) Kenya. Infect. Immun , vol.72 , pp. 3331-3335
    • Laine, C.1    Mwangi, T.2    Thompson, C.M.3    Obiero, J.4    Lipsitch, M.5    Scott, J.A.6
  • 17
    • 0037017388 scopus 로고    scopus 로고
    • The immune response to pneumococcal proteins during experimental human carriage
    • McCool, T. L., T. R. Cate, G. Moy, and J. N. Weiser. 2002. The immune response to pneumococcal proteins during experimental human carriage. J. Exp. Med. 195:359-365.
    • (2002) J. Exp. Med , vol.195 , pp. 359-365
    • McCool, T.L.1    Cate, T.R.2    Moy, G.3    Weiser, J.N.4
  • 18
    • 0141780964 scopus 로고    scopus 로고
    • Serum immunoglobulin G response to candidate vaccine antigens during experimental human pneumococcal colonization
    • McCool, T. L., T. R. Cate, E. I. Tuomanen, P. Adrian, T. J. Mitchell, and J. N. Weiser. 2003. Serum immunoglobulin G response to candidate vaccine antigens during experimental human pneumococcal colonization. Infect. Immun. 71:5724-5732.
    • (2003) Infect. Immun , vol.71 , pp. 5724-5732
    • McCool, T.L.1    Cate, T.R.2    Tuomanen, E.I.3    Adrian, P.4    Mitchell, T.J.5    Weiser, J.N.6
  • 19
    • 0028603597 scopus 로고
    • Localization of protection-eliciting epitopes on PspA of Streptococcus pneumoniae between amino acid residues 192 and 260
    • McDaniel, L. S., B. A. Ralph, D. O. McDaniel, and D. E. Briles. 1994. Localization of protection-eliciting epitopes on PspA of Streptococcus pneumoniae between amino acid residues 192 and 260. Microb. Pathog. 17:323-337.
    • (1994) Microb. Pathog , vol.17 , pp. 323-337
    • McDaniel, L.S.1    Ralph, B.A.2    McDaniel, D.O.3    Briles, D.E.4
  • 20
    • 0036718276 scopus 로고    scopus 로고
    • Analysis of serum cross-reactivity and cross-protection elicited by immunization with DNA vaccines against Streptococcus pneumoniae expressing PspA fragments from different clades
    • Miyaji, E. N., D. M. Ferreira, A. P. Lopes, M. C. Brandileone, W. O. Dias, and L. C. Leite. 2002. Analysis of serum cross-reactivity and cross-protection elicited by immunization with DNA vaccines against Streptococcus pneumoniae expressing PspA fragments from different clades. Infect. Immun. 70:5086-5090.
    • (2002) Infect. Immun , vol.70 , pp. 5086-5090
    • Miyaji, E.N.1    Ferreira, D.M.2    Lopes, A.P.3    Brandileone, M.C.4    Dias, W.O.5    Leite, L.C.6
  • 21
    • 0034002412 scopus 로고    scopus 로고
    • Immunization of healthy adults with a single recombinant pneumococcal surface protein A (PspA) variant stimulates broadly cross-reactive antibodies to heterologous PspA molecules
    • Nabors, G. S., P. A. Braun, D. J. Herrmann, M. L. Heise, D. J. Pyle, S. Gravenstein, M. Schilling, L. M. Ferguson, S. K. Hollingshead, D. E. Briles, and R. S. Becker. 2000. Immunization of healthy adults with a single recombinant pneumococcal surface protein A (PspA) variant stimulates broadly cross-reactive antibodies to heterologous PspA molecules. Vaccine 18:1743-1754.
    • (2000) Vaccine , vol.18 , pp. 1743-1754
    • Nabors, G.S.1    Braun, P.A.2    Herrmann, D.J.3    Heise, M.L.4    Pyle, D.J.5    Gravenstein, S.6    Schilling, M.7    Ferguson, L.M.8    Hollingshead, S.K.9    Briles, D.E.10    Becker, R.S.11
  • 22
    • 0034114443 scopus 로고    scopus 로고
    • Immunization of mice with combinations of pneumococcal virulence proteins elicits enhanced protection against challenge with Streptococcus pneumoniae
    • Ogunniyi, A. D., R. L. Folland, D. E. Briles, S. K. Hollingshead, and J. C. Paton. 2000. Immunization of mice with combinations of pneumococcal virulence proteins elicits enhanced protection against challenge with Streptococcus pneumoniae. Infect. Immun. 68:3028-3033.
    • (2000) Infect. Immun , vol.68 , pp. 3028-3033
    • Ogunniyi, A.D.1    Folland, R.L.2    Briles, D.E.3    Hollingshead, S.K.4    Paton, J.C.5
  • 24
    • 0033800920 scopus 로고    scopus 로고
    • Natural development of antibodies to pneumococcal surface protein A, pneumococcal surface adhesin A, and pneumolysin in relation to pneumococcal carriage and acute otitis media
    • Rapola, S., V. Jantti, R. Haikala, R. Syrjanen, G. M. Carlone, J. S. Sampson, D. E. Briles, J. C. Paton, A. K. Takala, T. M. Kilpi, and H. Kayhty. 2000. Natural development of antibodies to pneumococcal surface protein A, pneumococcal surface adhesin A, and pneumolysin in relation to pneumococcal carriage and acute otitis media. J. Infect. Dis. 182:1146-1152.
    • (2000) J. Infect. Dis , vol.182 , pp. 1146-1152
    • Rapola, S.1    Jantti, V.2    Haikala, R.3    Syrjanen, R.4    Carlone, G.M.5    Sampson, J.S.6    Briles, D.E.7    Paton, J.C.8    Takala, A.K.9    Kilpi, T.M.10    Kayhty, H.11
  • 25
    • 10344233687 scopus 로고    scopus 로고
    • The virulence function of Streptococcus pneumoniae surface protein A involves inhibition of complement activation and impairment of complement receptor-mediated protection
    • Ren, B., M. A. McCrory, C. Pass, D. C. Bullard, C. M. Ballantyne, Y. Xu, D. E. Briles, and A. J. Szalai. 2004. The virulence function of Streptococcus pneumoniae surface protein A involves inhibition of complement activation and impairment of complement receptor-mediated protection. J. Immunol. 173:7506-7512.
    • (2004) J. Immunol , vol.173 , pp. 7506-7512
    • Ren, B.1    McCrory, M.A.2    Pass, C.3    Bullard, D.C.4    Ballantyne, C.M.5    Xu, Y.6    Briles, D.E.7    Szalai, A.J.8
  • 26
    • 0346881409 scopus 로고    scopus 로고
    • Effects of PspA and antibodies to PspA on activation and deposition of complement on the pneumococcal surface
    • Ren, B., A. J. Szalai, S. K. Hollingshead, and D. E. Briles. 2004. Effects of PspA and antibodies to PspA on activation and deposition of complement on the pneumococcal surface. Infect. Immun. 72:114-122.
    • (2004) Infect. Immun , vol.72 , pp. 114-122
    • Ren, B.1    Szalai, A.J.2    Hollingshead, S.K.3    Briles, D.E.4
  • 27
    • 0037222829 scopus 로고    scopus 로고
    • Both family 1 and family 2 PspA proteins can inhibit complement deposition and confer virulence to a capsular serotype 3 strain of Streptococcus pneumoniae
    • Ren, B., A. J. Szalai, O. Thomas, S. K. Hollingshead, and D. E. Briles. 2003. Both family 1 and family 2 PspA proteins can inhibit complement deposition and confer virulence to a capsular serotype 3 strain of Streptococcus pneumoniae. Infect. Immun. 71:75-85.
    • (2003) Infect. Immun , vol.71 , pp. 75-85
    • Ren, B.1    Szalai, A.J.2    Thomas, O.3    Hollingshead, S.K.4    Briles, D.E.5
  • 28
    • 0042265132 scopus 로고    scopus 로고
    • Relative roles of genetic background and variation in PspA in the ability of antibodies to PspA to protect against capsular type 3 and 4 strains of Streptococcus pneumoniae
    • Roche, H., B. Ren, L. S. McDaniel, A. Hakansson, and D. E. Briles. 2003. Relative roles of genetic background and variation in PspA in the ability of antibodies to PspA to protect against capsular type 3 and 4 strains of Streptococcus pneumoniae. Infect. Immun. 71:4498-4505.
    • (2003) Infect. Immun , vol.71 , pp. 4498-4505
    • Roche, H.1    Ren, B.2    McDaniel, L.S.3    Hakansson, A.4    Briles, D.E.5
  • 29
    • 33645111218 scopus 로고    scopus 로고
    • Multilocus sequence types, serotypes, and variants of the surface antigen PspA in Streptococcus pneumoniae isolates from meningitis patients in Poland. Clin
    • Sadowy, E., A. Skoczynska, J. Fiett, M. Gniadkowski, and W. Hryniewicz. 2006. Multilocus sequence types, serotypes, and variants of the surface antigen PspA in Streptococcus pneumoniae isolates from meningitis patients in Poland. Clin. Vaccine Immunol. 13:139-144.
    • (2006) Vaccine Immunol , vol.13 , pp. 139-144
    • Sadowy, E.1    Skoczynska, A.2    Fiett, J.3    Gniadkowski, M.4    Hryniewicz, W.5
  • 30
    • 4544281498 scopus 로고    scopus 로고
    • Shaper, M., S. K. Hollingshead, W. H. Benjamin, Jr., and D. E. Briles. 2004. PspA protects Streptococcus pneumoniae from killing by apolactoferrin, and antibody to PspA enhances killing of pneumococci by apolactoferrin. Infect. Immun. 72:5031-5040. (Erratum, 72:7379.)
    • Shaper, M., S. K. Hollingshead, W. H. Benjamin, Jr., and D. E. Briles. 2004. PspA protects Streptococcus pneumoniae from killing by apolactoferrin, and antibody to PspA enhances killing of pneumococci by apolactoferrin. Infect. Immun. 72:5031-5040. (Erratum, 72:7379.)
  • 31
  • 32
    • 0037108670 scopus 로고    scopus 로고
    • Pneumococcal carriage and otitis media induce salivary antibodies to pneumococcal capsular polysaccharides in children
    • Simell, B., T. M. Kilpi, and H. Kayhty. 2002. Pneumococcal carriage and otitis media induce salivary antibodies to pneumococcal capsular polysaccharides in children. J. Infect. Dis. 186:1106-1114.
    • (2002) J. Infect. Dis , vol.186 , pp. 1106-1114
    • Simell, B.1    Kilpi, T.M.2    Kayhty, H.3
  • 33
    • 0035869106 scopus 로고    scopus 로고
    • Pneumococcal carriage and otitis media induce salivary antibodies to pneumococcal surface adhesin A, pneumolysin, and pneumococcal surface protein A in children
    • Simell, B., M. Korkeila, H. Pursiainen, T. M. Kilpi, and H. Kayhty. 2001. Pneumococcal carriage and otitis media induce salivary antibodies to pneumococcal surface adhesin A, pneumolysin, and pneumococcal surface protein A in children. J. Infect. Dis. 183:887-896.
    • (2001) J. Infect. Dis , vol.183 , pp. 887-896
    • Simell, B.1    Korkeila, M.2    Pursiainen, H.3    Kilpi, T.M.4    Kayhty, H.5
  • 34
    • 38449107305 scopus 로고    scopus 로고
    • Antibodies to pneumococcal surface protein A families 1 and 2 in serum and saliva of children and the risk of pneumococcal acute otitis media
    • Simell, B., M. Melin, M. Lahdenkari, D. E. Briles, S. K. Hollingshead, T. M. Kilpi, and H. Kayhty. 2007. Antibodies to pneumococcal surface protein A families 1 and 2 in serum and saliva of children and the risk of pneumococcal acute otitis media. J. Infect. Dis. 196:1528-1536.
    • (2007) J. Infect. Dis , vol.196 , pp. 1528-1536
    • Simell, B.1    Melin, M.2    Lahdenkari, M.3    Briles, D.E.4    Hollingshead, S.K.5    Kilpi, T.M.6    Kayhty, H.7
  • 35
    • 0035450277 scopus 로고    scopus 로고
    • Natural development of antibodies to pneumococcal capsular polysaccharides depends on the serotype: Association with pneumococcal carriage and acute otitis media in young children
    • Soininen, A., H. Pursiainen, T. Kilpi, and H. Kayhty. 2001. Natural development of antibodies to pneumococcal capsular polysaccharides depends on the serotype: association with pneumococcal carriage and acute otitis media in young children. J. Infect. Dis. 184:569-576.
    • (2001) J. Infect. Dis , vol.184 , pp. 569-576
    • Soininen, A.1    Pursiainen, H.2    Kilpi, T.3    Kayhty, H.4
  • 36
    • 55449086779 scopus 로고    scopus 로고
    • Suzumoto, M., M. Hotomi, D. S. Billal, D. E. Briles, S. K. Hollingshead, N. Yasui, and N. Yamanaka. 2003. Abstr. 43rd Intersci. Conf. Antimicrob. Agents Chemother., abstr. G-276.
    • Suzumoto, M., M. Hotomi, D. S. Billal, D. E. Briles, S. K. Hollingshead, N. Yasui, and N. Yamanaka. 2003. Abstr. 43rd Intersci. Conf. Antimicrob. Agents Chemother., abstr. G-276.
  • 37
    • 0035882435 scopus 로고    scopus 로고
    • Nasopharyngeal carriage of Streptococcus pneumoniae in Finnish children younger than 2 years old
    • Syrjänen, R. K., T. M. Kilpi, T. H. Kaijalainen, E. E. Herva, and A. K. Takala. 2001. Nasopharyngeal carriage of Streptococcus pneumoniae in Finnish children younger than 2 years old. J. Infect. Dis. 184:451-459.
    • (2001) J. Infect. Dis , vol.184 , pp. 451-459
    • Syrjänen, R.K.1    Kilpi, T.M.2    Kaijalainen, T.H.3    Herva, E.E.4    Takala, A.K.5
  • 38
    • 0030034830 scopus 로고    scopus 로고
    • Truncated Streptococcus pneumoniae PspA molecules elicit cross-protective immunity against pneumococcal challenge in mice
    • Tart, R. C., L. S. McDaniel, B. A. Ralph, and D. E. Briles. 1996. Truncated Streptococcus pneumoniae PspA molecules elicit cross-protective immunity against pneumococcal challenge in mice. J. Infect. Dis. 173:380-386.
    • (1996) J. Infect. Dis , vol.173 , pp. 380-386
    • Tart, R.C.1    McDaniel, L.S.2    Ralph, B.A.3    Briles, D.E.4
  • 39
    • 0032797913 scopus 로고    scopus 로고
    • Pneumococcal surface protein A inhibits complement activation by Streptococcus pneumoniae
    • Tu, A. H., R. L. Fulgham, M. A. McCrory, D. E. Briles, and A. J. Szalai. 1999. Pneumococcal surface protein A inhibits complement activation by Streptococcus pneumoniae. Infect. Immun. 67:4720-4724.
    • (1999) Infect. Immun , vol.67 , pp. 4720-4724
    • Tu, A.H.1    Fulgham, R.L.2    McCrory, M.A.3    Briles, D.E.4    Szalai, A.J.5
  • 41
    • 0032820153 scopus 로고    scopus 로고
    • Effects of active immunization with a pneumococcal surface protein (PspA) and of locally applied antibodies in experimental otitis media
    • White, P., A. Hermansson, C. Svanborg, D. Briles, and K. Prellner. 1999. Effects of active immunization with a pneumococcal surface protein (PspA) and of locally applied antibodies in experimental otitis media. ORL J. Otorhinolaryngol. Relat. Spec. 61:206-211.
    • (1999) ORL J. Otorhinolaryngol. Relat. Spec , vol.61 , pp. 206-211
    • White, P.1    Hermansson, A.2    Svanborg, C.3    Briles, D.4    Prellner, K.5
  • 42
    • 0030934988 scopus 로고    scopus 로고
    • Intranasal immunization of mice with PspA (pneumococcal surface protein A) can prevent intranasal carriage, pulmonary infection, and sepsis with Streptococcus pneumoniae
    • Wu, H. Y., M. H. Nahm, Y. Guo, M. W. Russell, and D. E. Briles. 1997. Intranasal immunization of mice with PspA (pneumococcal surface protein A) can prevent intranasal carriage, pulmonary infection, and sepsis with Streptococcus pneumoniae. J. Infect. Dis. 175:839-846.
    • (1997) J. Infect. Dis , vol.175 , pp. 839-846
    • Wu, H.Y.1    Nahm, M.H.2    Guo, Y.3    Russell, M.W.4    Briles, D.E.5
  • 43
    • 0026501145 scopus 로고
    • Structural properties and evolutionary relationships of PspA, a surface protein of Streptococcus pneumoniae, as revealed by sequence analysis
    • Yother, J., and D. E. Briles. 1992. Structural properties and evolutionary relationships of PspA, a surface protein of Streptococcus pneumoniae, as revealed by sequence analysis. J. Bacteriol. 174:601-609.
    • (1992) J. Bacteriol , vol.174 , pp. 601-609
    • Yother, J.1    Briles, D.E.2


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