PspA and PspC: Their potential for use as pneumococcal vaccines

Microbial Drug Resistance

Volumn 3, Issue 4, 1997, Pages 401-408

  Briles, David E ^a,b,f   Hollingshead, Susan K ^a   Swiatlo, Edwin ^a,c   Brooks Walter, Alexis ^a   Szalai, Alex ^b,c   Virolainen, Anni ^a   McDaniel, Larry S ^a   Benton, Kimberly A ^a   White, Peter ^d   Prellner, Karin ^d   Hermansson, Anne ^d   Aerts, Piet C ^e   Van Dijk, Hans ^e   Crain, Marilyn J ^a,b  

^a University of Alabama at Birmingham   (United States)

^b University of Alabama at Birmingham   (United States)

^c University of Alabama at Birmingham   (United States)

^d LUND UNIVERSITY   (Sweden)

^e UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^f UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; PNEUMOCOCCUS VACCINE;

DRUG RESEARCH; INFECTION PREVENTION; NONHUMAN; PRIORITY JOURNAL; REVIEW; STREPTOCOCCUS INFECTION; STREPTOCOCCUS PNEUMONIAE; VACCINATION;

BACTERIA (MICROORGANISMS); PNEUMOCOCCUS; STREPTOCOCCUS; STREPTOCOCCUS PNEUMONIAE;

EID: 0031405882     PISSN: 10766294     EISSN: None     Source Type: Journal    
DOI: 10.1089/mdr.1997.3.401     Document Type: Review

References (15)

1. Aaberge, I.S., B. Hvalbye, and M. Løvik. 1996. Enhancement of Streptococcus pneumoniae serotype 6B infection in mice after passive immunization with human serum. Microb. Pathog. 21:125-137.
2. Anderson, P.M., Pichichero, R. Insel, P. Farsad, and M. Santosham. 1985. Capsular antigens noncovalently or covalently as-sociated with protein as vaccines to Haemophilus influenzae type b: Comparison in two-year-old children. J. Infect. Dis. 152:634-636.
3. Austrian, R. 1979. Pneumococcal vaccine: Development and prospects. Am. J. Med. 67:547-549.
4. Benson, C.E., and C.R. Sweeney. 1984. Isolation of Streptococcus pneumoniae type 3 from equine species. J. Clin. Microbiol. 20:1028-1030.
5. Benton, K.A., M.P. Everson, and D.E. Briles. 1995. A pneumolysin-negative mutant of Streptococcus pneumoniae causes chronic bactermia rather than acute sepsis in mice. Infect. Immun. 63:448-455.
6. Benton, K.A., J.C. Paton, and D.E. Briles. 1997. Differences in virulence for mice among Streptococcus pneumoniae strains of capsular types 2, 3, 4, 5, and 6 are not attributable to differences in pneumolysin production. Infect. Immun. 65:1237-1244.
7. Briles, D.E., C. Forman, J.C. Horowitz, J.E. Volanakis, W.H. Benjamin, Jr., L.S. McDaniel, J. Eldridge, and J. Brooks. 1989. Antipneumococcal effects of C-reactive protein and monoclonal antibodies to pneumococcal cell wall and capsular antigens. Infect. Immun. 57:1457-1464.
8. Briles, D.E., J.D. King, M.A. Gray, L.S. McDaniel, E. Swiatlo, and K.A. Benton. 1996. PspA, a protection-eliciting pneumococcal protein: Immunogenicity of isolated native PspA in mice. Vaccine 14:858-867.
9. Briles, D.E., E. Swiatlo, and K. Edwards. In Press. Vaccine strategies for Streptococcus pneumoniae. In D.L. Stevens and E. Kaplan (ed.), Streptococci. Oxford University Press, New York.
10. Briles, D.E., R.C. Tart, I. Swiatlo, J.P. Dillard, P. Smith, K.A Benton, B.A. Ralph, A. Brooks-Walter, M.J. Crain, S.K. Hollingshead, and L.S. McDaniel. Submitted. Pneumococcal diversity: Considerations for new vaccine strategies with an emphasis on pneumococcal surface protein A (PspA). Clin. Microbiol. Rev.
11. Briles, D.E., R.C. Tart, H.-Y. Wu, B.A. Ralph, M.W. Russell, and L.S. McDaniel. 1996. Systemic and mucosal protective immunity to pneumococcal surface protein A. New York Acad. Sci. 797:118-126.
12. Brooks-Walter, A., R.C. Tart, D.E. Briles, and S.K. Hollingshead. 1997. The pspC gene encodes a second pneumococcal surface protein homologous to the gene encoding the protection-eliciting PspA protein of Streptococcus pneumoniae.ASM Annual Meeting, 1997, p. 35.
13. Cowan, M.J., A.J. Ammann, D.W. Wara, V.M. Howie, L. Schultz, N. Doyle, and M. Kaplan. 1978. Pneumococcal polysaccharide immunization in infants and children. Pediatrics 62:721-727.
14. Crain, M.J., J.S. Scott, D.A. Robinson, T.J. Coffey, A. Brooks-Walter, L.S. McDaniel, and D.E. Briles. 1996. Evidence for the simultaneous expression of two PspAs by a clone of capsular serotype 6B Streptococcus pneumoniae. Microb. Pathog. 21:265-275.
15. Crain, M.J., W.D. Waltman, II, J.S. Turner, J. Yother, D.E. Talkington, L.M. McDaniel, B.M. Gray, and D.E. Briles. 1990. Pneumococcal surface protein A (PspA) is serologically highly variable and is expressed by all clinically important capsular serotypes of Streptococcus pneumoniae. Infect. Immun. 58:3293-3299.