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Volumn 97, Issue 8, 1996, Pages 1852-1859

Leukemia Inhibitory Factor (LIF) stimulates proopiomelanocortin (POMC) expression in a corticotroph cell line: Role of STAT pathway

Author keywords

ACTH; Cytokines; Leukemia inhibitory factor; Pituitary gene regulation; Pituitary signaling

Indexed keywords

CORTICOTROPIN; CORTICOTROPIN RELEASING FACTOR; DEXAMETHASONE; LEUKEMIA INHIBITORY FACTOR; MESSENGER RNA; PROOPIOMELANOCORTIN;

EID: 0029875561     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI118615     Document Type: Article
Times cited : (136)

References (39)
  • 2
    • 0026489221 scopus 로고
    • Interleukin-2 and interleukin-2 receptor expression in human corticotrophic adenoma and murine pituitary cell cultures
    • Arzt, E., G. Stelzer, U. Renner, M. Lange, O.A. Muller, and G.K. Stalla. 1992. Interleukin-2 and interleukin-2 receptor expression in human corticotrophic adenoma and murine pituitary cell cultures. J. Clin Invest 90:1944-1951.
    • (1992) J. Clin Invest , vol.90 , pp. 1944-1951
    • Arzt, E.1    Stelzer, G.2    Renner, U.3    Lange, M.4    Muller, O.A.5    Stalla, G.K.6
  • 4
    • 0023640247 scopus 로고
    • Release of multiple hormones by a direct action of interleukin-1 on pituitary cells
    • Bernton, E.W, J.E. Beach, J.W. Holaday, R.C. Smallndge and H C. Fein 1987. Release of multiple hormones by a direct action of interleukin-1 on pituitary cells Science (Wash DC) 238:519-521.
    • (1987) Science (Wash DC) , vol.238 , pp. 519-521
    • Bernton, E.W.1    Beach, J.E.2    Holaday, J.W.3    Smallndge, R.C.4    Fein, H.C.5
  • 5
    • 0024510284 scopus 로고
    • Effects of protein kinase-C related adrenocorticotrophin secretogogues and interleukin-1 on proopiome-lanocortin gene expression in rat anterior pituitary cells
    • Suda, T., F. Tozawa, T. Ushiyama, N. Tomori, T Sumitomo, Y Nakagami, M. Yamada, H. Demura, and K. Shizume. 1989. Effects of protein kinase-C related adrenocorticotrophin secretogogues and interleukin-1 on proopiome-lanocortin gene expression in rat anterior pituitary cells. Endocrinology. 124 1444-1449
    • (1989) Endocrinology , vol.124 , pp. 1444-1449
    • Suda, T.1    Tozawa, F.2    Ushiyama, T.3    Tomori, N.4    Sumitomo, T.5    Nakagami, Y.6    Yamada, M.7    Demura, H.8    Shizume, K.9
  • 6
    • 0024309583 scopus 로고
    • Interleukin-6 stimulates anterior pituitary hormone release in vitro
    • Spangelo, B.L., A.M. Judd, P.C. Isakson, and R.M. MacLeod. 1989 Interleukin-6 stimulates anterior pituitary hormone release in vitro. Endocrinology. 125:575.
    • (1989) Endocrinology , vol.125 , pp. 575
    • Spangelo, B.L.1    Judd, A.M.2    Isakson, P.C.3    MacLeod, R.M.4
  • 7
    • 0026584255 scopus 로고
    • Pituitary follicular cells secrete an inhibitor of aortic endothelial cell growth. identification as leukemia inhibitory factor
    • Ferrara, N., J. Winer, and W.J. Henzel. 1992. Pituitary follicular cells secrete an inhibitor of aortic endothelial cell growth. identification as leukemia inhibitory factor. Proc Natl Acad. Sci USA 89:698-702
    • (1992) Proc Natl Acad. Sci USA , vol.89 , pp. 698-702
    • Ferrara, N.1    Winer, J.2    Henzel, W.J.3
  • 8
    • 0028911746 scopus 로고
    • Human and murine pituitary expression of leukemia inhibitory factor: Novel intrapituitary regulation of adrenocorticotropin synthesis and secretion
    • Akita, S., J. Webster, S.G. Ren, H. Takino, J. Said, O. Zand, and S. Melmed. 1995. Human and murine pituitary expression of leukemia inhibitory factor: novel intrapituitary regulation of adrenocorticotropin synthesis and secretion. J Clin Invest. 95:1288-1298.
    • (1995) J Clin Invest. , vol.95 , pp. 1288-1298
    • Akita, S.1    Webster, J.2    Ren, S.G.3    Takino, H.4    Said, J.5    Zand, O.6    Melmed, S.7
  • 9
    • 0027585161 scopus 로고
    • The molecular biology of the CNTF receptor
    • Davis, S., and G.D. Yancopoulos. 1993. The molecular biology of the CNTF receptor Curr Opin Cell Biol. 5.281-285.
    • (1993) Curr Opin Cell Biol. , vol.5 , pp. 281-285
    • Davis, S.1    Yancopoulos, G.D.2
  • 10
    • 0027328343 scopus 로고
    • The alpha, betas, and kinases of cytokine receptor complexes
    • Stahl, N., and G.D. Yancopoulos. 1993. The alpha, betas, and kinases of cytokine receptor complexes. Cell. 74.587-590.
    • (1993) Cell , vol.74 , pp. 587-590
    • Stahl, N.1    Yancopoulos, G.D.2
  • 11
    • 0028117163 scopus 로고
    • Cytokine signal transduction
    • Kishimoto, T., T Taga, and S. Akira 1994 Cytokine signal transduction. Cell. 76:253-262.
    • (1994) Cell , vol.76 , pp. 253-262
    • Kishimoto, T.1    Taga, T.2    Akira, S.3
  • 19
    • 0028952414 scopus 로고
    • Activation of acute phase response factor (APRF)/STAT3 transcription factor by growth hormone
    • Campbell, G S . D J. Meyer, R. Raz, D.E. Levy, J. Schwartz, and C. Carter-Su. 1995. Activation of acute phase response factor (APRF)/STAT3 transcription factor by growth hormone. J Biol Chem 270:3974-3979.
    • (1995) J Biol Chem , vol.270 , pp. 3974-3979
    • Campbell, G.S.1    Meyer, D.J.2    Raz, R.3    Levy, D.E.4    Schwartz, J.5    Carter-Su, C.6
  • 20
    • 0026723419 scopus 로고
    • A transcription factor with SH2 and SH3 domains is directly activated by an interferon alpha-induced cytoplasmic protein kinase(s)
    • Fu, X.-Y. 1992 A transcription factor with SH2 and SH3 domains is directly activated by an interferon alpha-induced cytoplasmic protein kinase(s). Cell. 70:323-335
    • (1992) Cell , vol.70 , pp. 323-335
    • Fu, X.-Y.1
  • 21
    • 0026725868 scopus 로고
    • Proteins of transcription factor ISGF3: One gene encodes the p91 and p84kDa proteins that are activated by interferon alpha
    • Schindler, C., X.-Y Fu, T. Improta, R. Aebersold, and J.E. Darnell. 1992. Proteins of transcription factor ISGF3: one gene encodes the p91 and p84kDa proteins that are activated by interferon alpha. Proc. Natl Acad Sci. USA. 89:7836-7839.
    • (1992) Proc. Natl Acad Sci. USA , vol.89 , pp. 7836-7839
    • Schindler, C.1    Fu, X.-Y.2    Improta, T.3    Aebersold, R.4    Darnell, J.E.5
  • 22
    • 0027090310 scopus 로고
    • Activation of transcription by interferon gamma: Tyrosine phosphorylation of a 91 kDa DNA binding protein
    • Schuai, K , C Schindler, V.R. Prezioso, and J.E. Darnell 1992. Activation of transcription by interferon gamma: tyrosine phosphorylation of a 91 kDa DNA binding protein. Science (Wash. DC). 258:1808-1812.
    • (1992) Science (Wash. DC) , vol.258 , pp. 1808-1812
    • Schuai, K.1    Schindler, C.2    Prezioso, V.R.3    Darnell, J.E.4
  • 23
    • 0028848026 scopus 로고
    • In vivo growth hormone treatment rapidly stimulates the tyrosine phosphorylation and activation of STAT-3
    • Gronowski, A M., Z. Zhong, Z. Wen, M.J Thomas, J. E. Darnell, and P Rotwein. 1995. In vivo growth hormone treatment rapidly stimulates the tyrosine phosphorylation and activation of STAT-3. Mol. Endocrinol. 9:171-177.
    • (1995) Mol. Endocrinol. , vol.9 , pp. 171-177
    • Gronowski, A.M.1    Zhong, Z.2    Wen, Z.3    Thomas, M.J.4    Darnell, J.E.5    Rotwein, P.6
  • 24
    • 0028338714 scopus 로고
    • Prolactin activates the interferon-regulated p91 transcription factor and the JAK-2 kinase by tyrosine phosphorylation
    • David, M., E.F. Petricoin, K.-I. Igarashi, G.M. Feldman, D.S. Finbloom, and A.C. Larner. 1994. Prolactin activates the interferon-regulated p91 transcription factor and the JAK-2 kinase by tyrosine phosphorylation Proc. Natl. Acad. Sci. USA. 91:7174-7178.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 7174-7178
    • David, M.1    Petricoin, E.F.2    Igarashi, K.-I.3    Feldman, G.M.4    Finbloom, D.S.5    Larner, A.C.6
  • 25
    • 0027327484 scopus 로고
    • Jak2 associates with the erythropoietin receptor and is tyrosine phosphorylated and activated following stimulation with erythropoietin
    • Witthuhn, B.A., F.W. Quelle, O. Silvennoinen, T. Yi, B. Tang, S. Miura, and J.N. Ihle. 1993. Jak2 associates with the erythropoietin receptor and is tyrosine phosphorylated and activated following stimulation with erythropoietin. Cell. 74:227-236.
    • (1993) Cell , vol.74 , pp. 227-236
    • Witthuhn, B.A.1    Quelle, F.W.2    Silvennoinen, O.3    Yi, T.4    Tang, B.5    Miura, S.6    Ihle, J.N.7
  • 26
    • 0028099408 scopus 로고
    • Differential tyrosine phosphorylation of JAK1, JAK2 and STAT1 by growth hormone and interferon gamma in IM-9 cells
    • Silva, C.M., H. Lu, M.J Weber, and M.O. Thorner. 1994. Differential tyrosine phosphorylation of JAK1, JAK2 and STAT1 by growth hormone and interferon gamma in IM-9 cells. J. Biol. Chem. 269:27532-27539.
    • (1994) J. Biol. Chem. , vol.269 , pp. 27532-27539
    • Silva, C.M.1    Lu, H.2    Weber, M.J.3    Thorner, M.O.4
  • 27
    • 0027493650 scopus 로고
    • A single phosphotyrosine residue of STAT91 required for gene activation by interferon-gamma
    • Shuai, K., G.R. Stark, I.M Kerr, and J.E. Darnell. 1993. A single phosphotyrosine residue of STAT91 required for gene activation by interferon-gamma Science (Wash. DC). 261:1744-1746
    • (1993) Science (Wash. DC) , vol.261 , pp. 1744-1746
    • Shuai, K.1    Stark, G.R.2    Kerr, I.M.3    Darnell, J.E.4
  • 28
    • 0028175969 scopus 로고
    • Interferon gamma induces tyrosine phosphorylation of interferon gamma receptor and regulated association of protein tyrosine kinases. Jak1 and Jak2, with its receptor
    • Igarashi, K.-I., G Garott, L Ozmen, A. Ziemiecki, A.F. Wilks, A.G. Harpur, A.C. Larner, and D S. Finbloom. 1994. Interferon gamma induces tyrosine phosphorylation of interferon gamma receptor and regulated association of protein tyrosine kinases. Jak1 and Jak2, with its receptor. J. Biol Chem. 269: 14333-14336.
    • (1994) J. Biol Chem. , vol.269 , pp. 14333-14336
    • Igarashi, K.-I.1    Garott, G.2    Ozmen, L.3    Ziemiecki, A.4    Wilks, A.F.5    Harpur, A.G.6    Larner, A.C.7    Finbloom, D.S.8
  • 29
    • 0027511822 scopus 로고
    • In vitro activation of the transcription factor gamma interferon. evidence for a tyrosine phosphatase/kinase signalling cascade
    • Igarashi, K.-I., M David, D.S. Finbloom, and A.C. Larner 1993. In vitro activation of the transcription factor gamma interferon. evidence for a tyrosine phosphatase/kinase signalling cascade. Mol. Cell. Biol. 13:1634-1640.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 1634-1640
    • Igarashi, K.-I.1    David, M.2    Finbloom, D.S.3    Larner, A.C.4
  • 30
    • 0028234529 scopus 로고
    • Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signalling proteins
    • Darnell, J.E., I.M. Kerr, and G.R. Stark. 1994. Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signalling proteins Science (Wash. DC) 264:1415-1421.
    • (1994) Science (Wash. DC) , vol.264 , pp. 1415-1421
    • Darnell, J.E.1    Kerr, I.M.2    Stark, G.R.3
  • 31
    • 0026377660 scopus 로고
    • The protooncogene c-fos is induced by corticotropin-releasing factor and stimulates proopiomelanocortin gene transcription in pituitary cells
    • Boutellier, A -M., P. Sassone-Corsi, and J.P. Loeffler. 1991. The protooncogene c-fos is induced by corticotropin-releasing factor and stimulates proopiomelanocortin gene transcription in pituitary cells. Mol Endocrinol. 5: 1301-1310.
    • (1991) Mol Endocrinol. , vol.5 , pp. 1301-1310
    • Boutellier, A.M.1    Sassone-Corsi, P.2    Loeffler, J.P.3
  • 33
    • 0028303977 scopus 로고
    • Molecular cloning of APRF, a novel interferon-stimulated gene factor3 p91-related transcription factor involved in the gp130-mediated signaling pathway
    • Akira, S., Y. Nishio, M. Inoue, X.-J. Wang, S. Wei, T. Matsusaka, K. Yoshida, T. Sudo, M Naruto, and T. Kishimoto. 1994. Molecular cloning of APRF, a novel interferon-stimulated gene factor3 p91-related transcription factor involved in the gp130-mediated signaling pathway. Cell. 77:63-71.
    • (1994) Cell , vol.77 , pp. 63-71
    • Akira, S.1    Nishio, Y.2    Inoue, M.3    Wang, X.-J.4    Wei, S.5    Matsusaka, T.6    Yoshida, K.7    Sudo, T.8    Naruto, M.9    Kishimoto, T.10
  • 34
    • 0026408605 scopus 로고
    • Proopiomelanocortin gene promoter elements required for constitutive and glucocorticoid-repressed transcription
    • Riegel, A.T , Y. Lu, J. Remenick, R.G. Wolford, D.S. Berard, and G.L. Hager. 1991. Proopiomelanocortin gene promoter elements required for constitutive and glucocorticoid-repressed transcription. Mol. Endocrinol. 5:1971-1982.
    • (1991) Mol. Endocrinol. , vol.5 , pp. 1971-1982
    • Riegel, A.T.1    Lu, Y.2    Remenick, J.3    Wolford, R.G.4    Berard, D.S.5    Hager, G.L.6
  • 35
    • 0028090266 scopus 로고
    • Characterization of a corticotropin-releasing hormone-responsive element in the rat proopiomelanocortin gene promoter and molecular cloning of its binding protein
    • Jin, W.D., A.-M. Boutellier, M.J. Glucksman, S.R J. Salton, J.-P. Loeffler, and J.L Roberts. 1994. Characterization of a corticotropin-releasing hormone-responsive element in the rat proopiomelanocortin gene promoter and molecular cloning of its binding protein. Mol. Endocrinol. 8:1377-1388
    • (1994) Mol. Endocrinol. , vol.8 , pp. 1377-1388
    • Jin, W.D.1    Boutellier, A.-M.2    Glucksman, M.J.3    Salton, S.R.J.4    Loeffler, J.-P.5    Roberts, J.L.6
  • 36
    • 0027997814 scopus 로고
    • Hypothalamic-pituitary-adrenal axis activation and stimulation of systemic vasopressin secretion by recombinant interleukin-6 in humans: Potential implications for the syndrome of inappropriate vasopressin secretion
    • Mastorakos, G , J.S. Weber. A.-M. Magiakou, H. Gunn, and G.P. Chrousos. 1994. Hypothalamic-pituitary-adrenal axis activation and stimulation of systemic vasopressin secretion by recombinant interleukin-6 in humans: potential implications for the syndrome of inappropriate vasopressin secretion. J. Clin. Endocrinol. & Metab. 79:934-939.
    • (1994) J. Clin. Endocrinol. & Metab. , vol.79 , pp. 934-939
    • Mastorakos, G.1    Weber, J.S.2    Magiakou, A.-M.3    Gunn, H.4    Chrousos, G.P.5
  • 37
    • 0029038988 scopus 로고
    • Corticotropin-releasing hormone stimulates proopiomelanocortin transcription by c-fos dependent and independent pathways: Characterization of an AP-1 site in exon
    • Boutellier, A.-N.M., D. Maurer, D. Larang, J.R. Lundblad, J.L Roberts, and J.P. Loeffler. 1995. Corticotropin-releasing hormone stimulates proopiomelanocortin transcription by c-fos dependent and independent pathways: characterization of an AP-1 site in exon. Mol. Endocrinol. 9:745-755.
    • (1995) Mol. Endocrinol. , vol.9 , pp. 745-755
    • Boutellier, A.-N.M.1    Maurer, D.2    Larang, D.3    Lundblad, J.R.4    Roberts, J.L.5    Loeffler, J.P.6
  • 38
    • 0029037126 scopus 로고
    • The hypothalamic pituitary adrenal axis and immune-mediated inflammation
    • Chrousos, G.P. 1995. The hypothalamic pituitary adrenal axis and immune-mediated inflammation. N. Engl. J. Med. 332:1351-1362.
    • (1995) N. Engl. J. Med. , vol.332 , pp. 1351-1362
    • Chrousos, G.P.1
  • 39
    • 0026585860 scopus 로고
    • Paradoxical responses of hypothalamic corticotropin-releasing factor (CRF) messenger ribonucleic acid (mRNA) and CRF-A1 peptide and adenohypophysical proopiomelanocortin mRNA during chronic inflammatory stress
    • Harbuz, M.S., R.G. Rees, D. Eckland, D.S. Jessop, D. Brewerton, and S.L Lightman. 1992. Paradoxical responses of hypothalamic corticotropin-releasing factor (CRF) messenger ribonucleic acid (mRNA) and CRF-A1 peptide and adenohypophysical proopiomelanocortin mRNA during chronic inflammatory stress. Endocrinology. 130:1394-1400.
    • (1992) Endocrinology , vol.130 , pp. 1394-1400
    • Harbuz, M.S.1    Rees, R.G.2    Eckland, D.3    Jessop, D.S.4    Brewerton, D.5    Lightman, S.L.6


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