Cyclic nucleotide-gated channels: A familiar channel family with a new function?

Future Cardiology

Volumn 4, Issue 5, 2008, Pages 505-515

  Wong, Ching On ^a   Yao, Xiaoqiang ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Ca2+; Cardiovascular; Cyclic nucleotide gated channel; Cyclic nucleotides; Endothelial cell

Indexed keywords

6 ANILINO 5,8 QUINOLINEQUINONE; ADRENOMEDULLIN; CALCITONIN GENE RELATED PEPTIDE; CALCIUM ION; CATION CHANNEL; CYCLIC AMP; CYCLIC GMP; CYCLIC NUCLEOTIDE; CYCLIC NUCLEOTIDE GATED CHANNEL; DILTIAZEM; GUANYLATE CYCLASE; SODIUM CALCIUM EXCHANGE PROTEIN; SODIUM ION; UNCLASSIFIED DRUG;

CALCIUM TRANSPORT; CARDIOVASCULAR SYSTEM; CELL FUNCTION; CHANNEL GATING; CHANNELOPATHY; ENZYME ACTIVATION; HUMAN; MEMBRANE POTENTIAL; NONHUMAN; OLFACTORY RECEPTOR; OLFACTORY SYSTEM; PHOTOTRANSDUCTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN FUNCTION; REVIEW; SIGNAL TRANSDUCTION; SODIUM TRANSPORT; VISUAL SYSTEM;

EID: 55249116794     PISSN: 14796678     EISSN: 17448298     Source Type: Journal    
DOI: 10.2217/14796678.4.5.505     Document Type: Review

References (69)

1. Fesenko EE, Kolesnikov SS, Lyubarsky AL: Induction by cyclic GMP of cationic conductance in plasma membrane of retinal rod outer segment. Nature 313(6000), 310-313 (1985).
2. Kaupp UB, Niidome T, Tanabe T et al.: Primary structure and functional expression from complementary DNA of the rod photoreceptor cyclic GMP-gated channel. Nature 342(6251), 762-776 (1989).
3. Kaupp UB, Seifert R: Cyclic nucleotide-gated ion channels. Physiol. Rev. 82(3), 769-824 (2002).
4. Kramer RH, Molokanova E: Modulation of cyclic-nucleotide-gated channels and regulation of vertebrate phototransduction. J. Exp. Biol. 204(Pt 17), 2921-2931 (2001).
5. Zagotta WN, Siegelbaum SA: Structure and function of cyclic nucleotide-gated channels. Annu. Rev. Neurosci. 19, 235-263 (1996).
6. 2+-binding site in the pore of cyclic nucleotide-gated channels: S5/S6 segments control affinity of intrapore glutamates. EMBO J. 18(1), 119-130 (1999).
7. Korschen HG, Illing M, Seifert R et al.: A 240 kDa protein represents the complete beta subunit of the cyclic nucleotide-gated channel from rod photoreceptor. Neuron 15(3), 627-636 (1995).
8. Bönigk W, Altenhofen W, Müller F et al.: Rod and cone photoreceptor cells express distinct genes for cGMP-gated channels. Neuron 10(5), 865-877 (1993).
9. Dhallan RS, Yau KW, Schrader KA, Reed RR: Primary structure and functional expression of a cyclic nucleotide-activated channel from olfactory neurons. Nature 347(6289), 184-187 (1990).
10. Gerstner A, Zong X, Hofmann F, Biel M: Molecular cloning and functional characterization of a new modulatory cyclic nucleotide-gated channel subunit from mouse retina. J. Neurosci. 20(4), 1324-1332 (2000).
11. Biel M, Zong X, Ludwig A, Sartter A, Hofmann F: Molecular cloning and expression of the Modulatory subunit of the cyclic nucleotide-gated cation channel. J. Biol. Chem. 271(11), 6349-6355 (1996).
12. Paoletti P, Young EC, Siegelbaum SA: C-linker of cyclic nucleotide-gated channels controls coupling of ligand binding to channel gating. J. Gen. Physiol. 113(1), 17-34 (1999).
13. Johnson JP Jr, Zagotta WN: Rotational movement during cyclic nucleotide-gated channel opening. Nature 412(6850), 917-921 (2001).
14. Nache V, Schulz E, Zimmer T et al.: Activation of olfactory-type cyclic. nucleotide-gated channels is highly cooperative. J. Physiol. 569(Pt 1), 91-102 (2005).
15. Meyer MR, Angele A, Kremmer E, Kaupp UB, Muller F: A cGMP-signaling pathway in a subset of olfactory sensory neurons. Proc. Natl Acad. Sci. USA 97(19), 10595-10600 (2000).
16. Gutièrrez-Mecinas M, Blasco-Ibáñez JM, Nàcher J, Varea E, Martínez-Guijarro FJ, Crespo C: Distribution of the A3 subunit of the cyclic nucleotide-gated ion channels in the main olfactory bulb of the rat. Neuroscience 153(4), 1164-1176 (2008).
17. Firestein S, Werblin F: Odor-induced membrane currents in vertebrate-olfactory receptor neurons. Science 244(4900), 79-82 (1989).
18. Bradley J, Bönigk W, Yau KW, Frings S: Calmodulin permanently associates with rat olfactory CNG channels under native conditions. Nat. Neurosci. 7(7), 705-710 (2004).
19. Dryja IP, Finn JI, Peng YW, McGee IL, Berson EL, Yau KW: Mutations in the gene encoding the a subunit of the rod cGMP-gated channel in autosomal recessive retinitis pigmentosa. Proc. Natl Acad. Sci. USA 92(22), 10177-10181 (1995).
20. Bareil C, Hamel CP, Delague V, Arnaud B, Demaille J, Claustres M: Segregation of a mutation in CNGB1 encoding the β-subunit of the rod cGMP-gated channel in a family with autosomal recessive retinitis pigmentosa. Hum. Genet. 108(4), 328-334 (2001).
21. Kohl S, Baumann B, Broghammer M et al.: Mutations in the CNGB3 gene encoding the β-subunit of the cone photoreceptor cGMP-gated channel are responsible for achromatopsia (ACHM3) linked to chromosome 8q21. Hum. Mol. Genet. 9(14), 2107-2116 (2000).
22. Biel M, Seeliger M, Pfeifer A et al.: Selective loss of cone function in mice lacking the cyclic nucleotide-gated channel CNG3. Proc. Natl Acad Sci. USA 96(13), 7553-7557 (1999).
23. Brunet LJ, Gold GH, Ngai J: General anosmia caused by a targeted disruption of the mouse olfactory cyclic nucleotide-gated cation channel. Neuron 17(4), 681-693 (1996).
24. 2+-calmodulin-dependent: odor adaptation. Science 294(5549), 2172-2175 (2001).
25. Kelliher KR, Ziesmann J, Munger SD, Reed RR, Zufall F: Importance of the CNGA4 channel gene for odor discrimination and adaptation in behaving mice. Proc. Natl Acad. Sci. USA 100(7), 4299-4304 (2003).
26. Hardman JG: Cyclic nucleotides and regulation of vascular smooth muscle. J. Cardiovasc. Pharmacol. 4, S639-S645 (1984).
27. 2+ influx pathways in vascular endothelial cells. Clin. Hemorheol. Microcirc. 37(1-2), 63-70 (2007).
28. Cheng KT, Chan FL, Huang Y, Chan WY, Yao X: Expression of olfactory-type cyclic nucleotide-gated channel (CNGA2) in vascular tissues. Histochem. Cell. Biol. 120(6), 475-481 (2003).
29. Cassar SC, Chen J, Zhang D, Gopalakrishnan M: Tissue specific expression of alternative splice forms of human cyclic nucleotide gated channel subunit CNGA3. Mol. Vis. 10, 808-813 (2004).
30. Yao X, Leung PS, Kwan HY, Wong TP, Fong MW: Rod-type cyclic nucleotide-gated cation channel is expressed in vascular endothelium and vascular smooth muscle cells. Cardiovasc. Res. 41(1), 282-290 (1999).
31. Ding C, Potter ED, Qiu W, Coon SL, Levine MA, Guggino SE: Cloning and widespread distribution of the rat rod-type cyclic nudeotide-gated cation channel. Am. J. Physiol. 272(4 Pt 1), C1335-C1344 (1997).
32. Ahmad I, Redmond LJ, Barnstable CJ: Developmental and tissue-specific expression of the rod photoreceptor cGMP-gated ion channel gene. Biochem. Biophys. Res. Commun. 173(1), 463-470 (1990).
33. Kruse LS, Sandholdt NT, Gammeltoft S, Olesen J, Kruuse C: Phosphodiesterase 3 and 5 and cyclic nucleotide-gated ion channel expression in rat trigeminovascular system. Neurosci. Lett. 404(1-2), 202-207 (2006).
34. Ruiz ML, London B, Nadal-Ginard B: Cloning and characterization of an olfactory cyclic nucleotide-gated channel expressed in mouse heart. J. Mol. Cell. Cardiol. 28(7), 1453-1461 (1996).
35. Biel M, Altenhofen W, Hullin R et al.: Primary stxucture and functional expression of a cyclic nucleotide-gated channel from rabbit aorta. FEBS Lett. 329(1-2), 134-138 (1993).
36. Biel M, Zong X, Distler M et al.: Another member of the cyclic nucleotide-gated channel family, expressed in testis, kidney, and heart. Proc. Natl Acad. Sci. USA 91(9), 3505-3509 (1994).
37. Distler M, Biel M, Flockerzi V, Hofmann F: Expression of cyclic nucleotide-gated cation channels in non-sensory tissues and cells. Neuropharmacology 330(11), 1275-1282 (1994).
38. Yao X, Garland CJ: Recent developments in vascular endothelial cell transient receptor potential channels. Circ. Res. 97(9), 853-863 (2005).
39. 2+ cycling in the heart. Biochem. Soc. Trans. 34(Pt 4), 489-491 (2006).
40. Chan HY, Yao X, Tsang SY, Bourreau JP, Chan FL, Huang Y: Isoproterenol amplifies 17 β-estradiol-mediated vasorelaxation: role of endothelium/nitric oxide and cyclic AMP. Cardiovasc. Res. 53(3), 627-633 (2002).
41. 2+ entry into endothelial cells by activation of potassium channels and membrane hyperpolarization. Biochem. J. 291 (Pt 1), 263-267 (1993).
42. Wu S, Moore TM, Brough GH et al.: Cyclic nucleotide-gated channels mediate membrane depolarization following activation of store-operated calcium entry in endothelial cells. J. Biol. Chem. 275(25), 18887-18896 (2000).
43. Zhang J, Xia SL, Block ER, Patel JM: NO upregulation of a cyclic nucleotide-gated channel contributes to calcium elevation in endothelial cells. Am. J. Physiol. Cell. Physiol. 283(4), C1080-C1089 (2002).
44. 2+ influx in vascular endothelial cells. Arterioscler. Thromb. Vasc. Biol. 28(5), 913-918 (2008).
45. Hewavitharana T, Deng X, Soboloff J, Gill DL: Role of STIM and Orai proteins in the store-operated calcium signaling pathway. Cell Calcium 42(2), 173-182 (2007).
46. Rump LC, Jabbari-T J, von Kügelgen I, Oberhauser V: Adenosine mediates nitric-oxide-independent renal vasodilation by activation of A2A receptors. J. Hypertens. 17(12 Pt 2), 1987-1993 (1999).
47. Kuo L, Chancellor JD: Adenosine potentiates flow-induced dilation of coronary arterioles by activating KATP channels in endothelium. Am. J. Physiol. 269(2 Pt2), H541-H549 (1995).
48. Brawley L, Shaw AM, MacDonald A: Role of endothelium/nitric oxide in atypical β-adrenoceptor-mediated relaxation in rat isolated aorta. Eur. J. Pharmacol. 398(2), 285-296 (2000).
49. Trochu JN, Leblais V Rautureau Y et al.: β3-adrenoceptor stimulation induces vasorelaxation mediated essentially by endothelium-derived nitric oxide in rat thoracic aorta. Br. J. Pharmacol. 128(1), 69-76 (1999).
50. Rubanyi G, Vanhoutte PM: Endothelium-removal decreases relaxations of canine coronary arteries caused by β-adrenergic agonists and adenosine. J. Cardiovasc. Pharmacol. 7(1), 139-144 (1985).
51. Busse R, Edwards G, Félétou M, Fleming I, Vanhoutte PM, Weston AH: EDHF: bringing the concepts together. Trends Pharmacol. Sci. 23(8), 374-380 (2002).
52. Fleming I, Busse R: Molecular mechanisms involved in the regulation of the endothelial nitric oxide synthase. Am. J. Physiol. Regul. Integr. Comp. Physiol. 284(1), R1-R12 (2003).
53. Tabrizchi R, Bedi S: Pharmacology of adenosine receptors in the vasculature. Pharmacol. Ther. 91(2), 133-147 (2001).
54. 2+. Am. J. Physiol. Heart. Circ. Physiol. 285(1), H26-H37 (2003).
55. Dessy C, Moniotte S, Ghisdal P, Havaux X, Noirhomme P, Balligand JL: Endothelial beta3-adrenoceptors mediate vasorelaxation of human coronary microarteries through nitric oxide and endothelium-dependent hyperpolarization. Circulation 110(8), 948-954 (2004).
56. Busse R, Fleming I: Regulation of endothelium-derived vasoactive autacoid production by hemodynamic forces. Trends Pharmacol. Sci. 24(1), 24-29 (2003).
57. Graier WF, Groschner K, Schmidt K, Kukovetz WR: Increases in endothelial cyclic AMP levels amplify agonist-induced formation of endothelium-derived relaxing factor (EDRF). Biochem. J. 288(Pt 2), 345-349 (1992).
58. 2+ influx in vascular endothelial cells is mediated by CNGA2 channels. J. Mol. Cell. Cardiol. DOI:10.1016/j.yjmcc. 2008.06.005 (2008) (Epub ahead of print).
59. Brain SD, Grant AD: Vascular actions of calcitonin gene-related peptide and adrenomedullin. Physiol. Rev. 84(3), 903-934 (2004).
60. Sayner S, Stevens T: Soluble adenylate cyclase reveals the significance of compartmentalized cAMP on endothelial cell barrier function. Biochem. Soc. Trans. 34(Pt 4), 492-494 (2006).
61. Ostrom RS, Liu X, Head BP, Gregorian C, Seasholtz TM, Insel PA: Localization of adenylyl cyclase isoforms and G protein-coupled receptors in vascular smooth muscle cells: expression in caveolin-rich and noncaveolin domains. Mol. Pharmacol. 62(5), 983-992 (2002).
62. Brady JD, Rich TC, Le X et al.: Functional role of lipid raft microdomains in cyclic nucleotide-gated channel activation. Mol. Pharmacol. 65(3), 503-511(2004).
63. Ding XQ, Fitzgerald JB, Matveev AV, McClellan ME, Elliott MH: Functional activity of photoreceptor cyclic nucleotide-gated channels is dependent on the integrity of cholesterol- and sphingolipid-enriched membrane domains. Biochemistry 47(12), 3677-3687 (2008).
64. 2 binding to bovine aortic endothelial cells. Biochim. Biophys. Acta 1570(2), 113-120 (2002).
65. Leinders-Zufall T, Zufall F: Block of cyclic nucleotide-gated channels in salamander olfactory receptor neurons by the guanylyl cyclase inhibitor LY83583. J. Neurophysiol. 74(6), 2759-2762 (1995).
66. Mülsch A, Lückhoff A, Pohl U et al.: LY83583 (6-anilino-5,8-quinolinedione) blocks nitrovasodilator-induced cyclic GMP increases and inhibition of platelet activation. Naunyn-Schmiedeberg's Arch. Pharmacol. 340, 119-125 (1989).
67. Frings S, Lynch JW, Lindemann B: Properties of cyclic nucleotide-gated channels mediating olfactory transduction. Activation, selectivity, and blockage. J. Gen. Physiol. 100(1), 45-67 (1992).
68. Haynes LW: Block of the cyclic GMP-gated channel of vertebrate rod and cone photoreceptors by L-cis-diltiazem. J. Gen. Physiol. 100(5), 783-801 (1992).
69. Hashimoto Y, Yabana H, Murata S: Electrophysiological effect of L-cis-diltiazem, the stereoisomer of D-cis-diltiazem, on isolated guinea-pig left ventricular myocytes. Eur. J. Pharmacol. 391(3), 217-223 (2000).