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Volumn 19, Issue 10, 2008, Pages 1951-1959

3-D tissue culture systems for the evaluation and optimization of nanoparticle-based drug carriers

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; CONTROLLED DRUG DELIVERY; MONOLAYERS; TARGETED DRUG DELIVERY; TISSUE; TISSUE CULTURE; TISSUE ENGINEERING;

EID: 55249103122     PISSN: 10431802     EISSN: None     Source Type: Journal    
DOI: 10.1021/bc800233a     Document Type: Review
Times cited : (183)

References (84)
  • 1
    • 0034193258 scopus 로고    scopus 로고
    • Role of extracellular matrix assembly in interstitial transport in solid tumors
    • Netti, P., Berk, D., Swartz, M., Grodzinsky, A., and Jain, R. (2000) Role of extracellular matrix assembly in interstitial transport in solid tumors. Cancer Res. 60, 2497-2503.
    • (2000) Cancer Res , vol.60 , pp. 2497-2503
    • Netti, P.1    Berk, D.2    Swartz, M.3    Grodzinsky, A.4    Jain, R.5
  • 3
    • 42249095831 scopus 로고    scopus 로고
    • Increased nanoparticle penetration in collagenase-treated multicellullar spheroids
    • Goodman, T. T., Olive, P. L., and Pun, S. H. (2007) Increased nanoparticle penetration in collagenase-treated multicellullar spheroids. Int. J. Nanomed. 2, 265-274.
    • (2007) Int. J. Nanomed , vol.2 , pp. 265-274
    • Goodman, T.T.1    Olive, P.L.2    Pun, S.H.3
  • 4
    • 2942715248 scopus 로고    scopus 로고
    • Human mesenchymal stem cells tissue development in 3D PET matrices
    • Grayson, W. L., Ma, T., and Bunnell, B. (2004) Human mesenchymal stem cells tissue development in 3D PET matrices. Biotechnol. Prog. 20, 905-912.
    • (2004) Biotechnol. Prog , vol.20 , pp. 905-912
    • Grayson, W.L.1    Ma, T.2    Bunnell, B.3
  • 5
    • 27644473227 scopus 로고    scopus 로고
    • Stimulatory effects of a three-dimensional microenvironment on cell-mediated fibronectin fibrillogenesis
    • Mao, Y., and Schwarzbauer, J. E. (2005) Stimulatory effects of a three-dimensional microenvironment on cell-mediated fibronectin fibrillogenesis. J. Cell Sci. 118, 4427-4436.
    • (2005) J. Cell Sci , vol.118 , pp. 4427-4436
    • Mao, Y.1    Schwarzbauer, J.E.2
  • 6
    • 0001779594 scopus 로고    scopus 로고
    • Human disc cells in monolayer vs 3D culture: Cell shape, division and matrix formation
    • Gruber, H. E., Jr. (2000) Human disc cells in monolayer vs 3D culture: cell shape, division and matrix formation. BMC Musculoskel. Dis. 1, 1.
    • (2000) BMC Musculoskel. Dis , vol.1 , pp. 1
    • Gruber Jr., H.E.1
  • 7
    • 0023879067 scopus 로고
    • Synthesis of extracellular matrix glycoproteins by a differentiated thyroid epithelial cell line
    • Garbi, C., Zurzolo, C., Bifulco, M., and Nitsch, L. (1988) Synthesis of extracellular matrix glycoproteins by a differentiated thyroid epithelial cell line. J. Cell. Physiol. 135, 39-46.
    • (1988) J. Cell. Physiol , vol.135 , pp. 39-46
    • Garbi, C.1    Zurzolo, C.2    Bifulco, M.3    Nitsch, L.4
  • 8
    • 33645791896 scopus 로고    scopus 로고
    • In vivo diffusion analysis with quantum dots and dextrans predicts the width of brain extracellular space
    • Thorne, R. G., and Nicholson, C. (2006) In vivo diffusion analysis with quantum dots and dextrans predicts the width of brain extracellular space. Proc. Natl. Acad. Sci. U.S.A. 103, 5567-72.
    • (2006) Proc. Natl. Acad. Sci. U.S.A , vol.103 , pp. 5567-5572
    • Thorne, R.G.1    Nicholson, C.2
  • 9
    • 41149086686 scopus 로고    scopus 로고
    • Extracellular barriers to in vivo PEI and PEGylated PEI polyplex-mediated gene delivery to the liver
    • Burke, R. S., and Pun, S. H. (2008) Extracellular barriers to in vivo PEI and PEGylated PEI polyplex-mediated gene delivery to the liver. Bioconjugate Chem. 19, 693-704.
    • (2008) Bioconjugate Chem , vol.19 , pp. 693-704
    • Burke, R.S.1    Pun, S.H.2
  • 10
    • 0344389048 scopus 로고    scopus 로고
    • Interactions of polymeric and liposomal gene delivery systems with extracellular glycosaminoglycans: Physicochemical and transfection studies
    • Ruponen, M., Yla-Herttuala, S., and Urtti, A. (1999) Interactions of polymeric and liposomal gene delivery systems with extracellular glycosaminoglycans: physicochemical and transfection studies. Biochim. Biophys. Acta, Biomembr. 1415, 331-341.
    • (1999) Biochim. Biophys. Acta, Biomembr , vol.1415 , pp. 331-341
    • Ruponen, M.1    Yla-Herttuala, S.2    Urtti, A.3
  • 12
    • 9144228701 scopus 로고    scopus 로고
    • Membrane-based PDMS microbioreactor for perfused 3D primary rat hepatocyte cultures
    • Ostrovidov, S., Jiang, J., Sakai, Y., and Fujii, T. (2004) Membrane-based PDMS microbioreactor for perfused 3D primary rat hepatocyte cultures. Biomed. Microdevices 6, 279-87.
    • (2004) Biomed. Microdevices , vol.6 , pp. 279-287
    • Ostrovidov, S.1    Jiang, J.2    Sakai, Y.3    Fujii, T.4
  • 13
    • 0032077407 scopus 로고    scopus 로고
    • Microfabrication of hepatocyte/fibroblast co-cultures: Role of homotypic cell interactions
    • Bhatia, S., Balis, U., Yarmush, M., and Toner, M. (1998) Microfabrication of hepatocyte/fibroblast co-cultures: Role of homotypic cell interactions. Biotechnol. Prog. 14, 378-387.
    • (1998) Biotechnol. Prog , vol.14 , pp. 378-387
    • Bhatia, S.1    Balis, U.2    Yarmush, M.3    Toner, M.4
  • 15
    • 33644794593 scopus 로고    scopus 로고
    • Three-dimensional co-culture of rat hepatocyte spheroids and NIH/3T3 fibroblasts enhances hepatocyte functional maintenance
    • Lu, H. F., Chua, K. N., Zhang, P. C., Lim, W. S., Ramakrishna, S., Leong, K. W., and Mao, H. Q. (2005) Three-dimensional co-culture of rat hepatocyte spheroids and NIH/3T3 fibroblasts enhances hepatocyte functional maintenance. Acta Biomater. 1, 399-410.
    • (2005) Acta Biomater , vol.1 , pp. 399-410
    • Lu, H.F.1    Chua, K.N.2    Zhang, P.C.3    Lim, W.S.4    Ramakrishna, S.5    Leong, K.W.6    Mao, H.Q.7
  • 16
    • 0024287687 scopus 로고
    • Metabolic interactions of parenchymal hepatocytes and dividing epithelial-cells in co-culture
    • Agius, L. (1988) Metabolic interactions of parenchymal hepatocytes and dividing epithelial-cells in co-culture. Biochem. J. 252, 23-28.
    • (1988) Biochem. J , vol.252 , pp. 23-28
    • Agius, L.1
  • 17
    • 0031608392 scopus 로고    scopus 로고
    • Maintained function of primary human hepatocytes by cellular interactions in coculture: Implications for liver support systems
    • Auth, M. K., Okamato, M., Ishida, Y., Keogh, A., Auth, S. H. G., Gerlach, J., Encke, A., McMaster, P., and Strain, A. J. (1998) Maintained function of primary human hepatocytes by cellular interactions in coculture: implications for liver support systems. Transpl. Int. 11, S439-S443.
    • (1998) Transpl. Int , vol.11
    • Auth, M.K.1    Okamato, M.2    Ishida, Y.3    Keogh, A.4    Auth, S.H.G.5    Gerlach, J.6    Encke, A.7    McMaster, P.8    Strain, A.J.9
  • 18
    • 27944497333 scopus 로고    scopus 로고
    • Tissue cells feel and respond to the stiffness of their substrate
    • Discher, D., Janmey, P., and Wang, Y. (2005) Tissue cells feel and respond to the stiffness of their substrate. Science 310, 1139-1143.
    • (2005) Science , vol.310 , pp. 1139-1143
    • Discher, D.1    Janmey, P.2    Wang, Y.3
  • 19
    • 15444368220 scopus 로고    scopus 로고
    • Cell type-specific response to growth on soft materials
    • Georges, P., and Janmey, P. (2005) Cell type-specific response to growth on soft materials. J. Appl. Phys. 98, 1547-1553.
    • (2005) J. Appl. Phys , vol.98 , pp. 1547-1553
    • Georges, P.1    Janmey, P.2
  • 21
    • 20144373766 scopus 로고    scopus 로고
    • Non-viral gene delivery regulated by stiffness of cell adhesion substrates
    • Kong, H. J., Liu, J., Riddle, K., Matsumoto, T., Leach, K., and Mooney, D. J. (2005) Non-viral gene delivery regulated by stiffness of cell adhesion substrates. Nat. Mater. 4, 460-4.
    • (2005) Nat. Mater , vol.4 , pp. 460-464
    • Kong, H.J.1    Liu, J.2    Riddle, K.3    Matsumoto, T.4    Leach, K.5    Mooney, D.J.6
  • 22
    • 0035941075 scopus 로고    scopus 로고
    • Taking cell-matrix adhesions to the third dimension
    • Cukierman, E., Pankov, R., Stevens, D., and Yamada, K. (2001) Taking cell-matrix adhesions to the third dimension. Science 294, 1708-1712.
    • (2001) Science , vol.294 , pp. 1708-1712
    • Cukierman, E.1    Pankov, R.2    Stevens, D.3    Yamada, K.4
  • 23
    • 33646032122 scopus 로고    scopus 로고
    • Probing the role of multicellular organization in three-dimensional microenvironments
    • Albrecht, D., Underhill, G., Wassermann, T., Sah, R., and Bhatia, S. (2006) Probing the role of multicellular organization in three-dimensional microenvironments. Nat. Methods 3, 369-375.
    • (2006) Nat. Methods , vol.3 , pp. 369-375
    • Albrecht, D.1    Underhill, G.2    Wassermann, T.3    Sah, R.4    Bhatia, S.5
  • 24
    • 0036906821 scopus 로고    scopus 로고
    • Three-dimensional photopatterning of hydrogels containing living cells
    • Liu, V., and Bhatia, S. (2002) Three-dimensional photopatterning of hydrogels containing living cells. Biomed. Microdevices 4, 257-266.
    • (2002) Biomed. Microdevices , vol.4 , pp. 257-266
    • Liu, V.1    Bhatia, S.2
  • 25
    • 33644529130 scopus 로고    scopus 로고
    • Capturing complex 3D tissue physiology in vitro
    • Griffith, L., and Swartz, M. (2006) Capturing complex 3D tissue physiology in vitro. Nat. Rev. Mol. Cell Biol. 7, 211-224.
    • (2006) Nat. Rev. Mol. Cell Biol , vol.7 , pp. 211-224
    • Griffith, L.1    Swartz, M.2
  • 26
    • 4944266313 scopus 로고    scopus 로고
    • High interstitial fluid pressure - An obstacle in cancer therapy
    • Heldin, C., Rubin, K., Pietras, K., and Ostman, A. (2004) High interstitial fluid pressure - An obstacle in cancer therapy. Nat. Rev. Cancer 4, 806-813.
    • (2004) Nat. Rev. Cancer , vol.4 , pp. 806-813
    • Heldin, C.1    Rubin, K.2    Pietras, K.3    Ostman, A.4
  • 27
    • 0033800091 scopus 로고    scopus 로고
    • Multicellular resistance: A paradigm for clinical resistance?
    • Desoize, B., and Jardillier, J. (2000) Multicellular resistance: a paradigm for clinical resistance? Crit. Rev. Oncol. Hematol. 36, 193-207.
    • (2000) Crit. Rev. Oncol. Hematol , vol.36 , pp. 193-207
    • Desoize, B.1    Jardillier, J.2
  • 28
    • 34648834682 scopus 로고    scopus 로고
    • The third dimension bridges the gap between cell culture and live tissue
    • Pampaloni, F., Reynaud, E., and Stelzer, E. (2007) The third dimension bridges the gap between cell culture and live tissue. Nat. Rev. Mol. Cell Biol. 8, 839-845.
    • (2007) Nat. Rev. Mol. Cell Biol , vol.8 , pp. 839-845
    • Pampaloni, F.1    Reynaud, E.2    Stelzer, E.3
  • 29
    • 33645155778 scopus 로고    scopus 로고
    • Characterization of superparamagnetic nanoparticle interactions with extracellular matrix in an in vitro system
    • Kuhn, S. J., Hallahan, D. E., and Giorgio, T. D. (2006) Characterization of superparamagnetic nanoparticle interactions with extracellular matrix in an in vitro system. Ann. Biomed. Eng. 34, 51-8.
    • (2006) Ann. Biomed. Eng , vol.34 , pp. 51-58
    • Kuhn, S.J.1    Hallahan, D.E.2    Giorgio, T.D.3
  • 30
  • 32
  • 33
    • 33644888606 scopus 로고    scopus 로고
    • Proteolytic surface functionalization enhances in vitro magnetic nanoparticle mobility through extracellular matrix
    • Kuhn, S. J., Finch, S. K., Hallahan, D. E., and Giorgio, T. D. (2006) Proteolytic surface functionalization enhances in vitro magnetic nanoparticle mobility through extracellular matrix. Nano Lett. 6, 306-312.
    • (2006) Nano Lett , vol.6 , pp. 306-312
    • Kuhn, S.J.1    Finch, S.K.2    Hallahan, D.E.3    Giorgio, T.D.4
  • 35
    • 0028063852 scopus 로고
    • Selective down-regulation of integrin receptors in spheroids of squamous cell carcinoma
    • Waleh, N. S., Gallo, J., Grant, T. D., Murphy, B. J., Kramer, R. H., and Sutherland, R. M. (1994) Selective down-regulation of integrin receptors in spheroids of squamous cell carcinoma. Cancer Res. 54, 838-43.
    • (1994) Cancer Res , vol.54 , pp. 838-843
    • Waleh, N.S.1    Gallo, J.2    Grant, T.D.3    Murphy, B.J.4    Kramer, R.H.5    Sutherland, R.M.6
  • 36
    • 0021279687 scopus 로고
    • Demonstration of an extracellular matrix in multicellular tumor spheroids
    • Nederman, T., Norling, B., Glimelius, B., Carlsson, J., and Brunk, U. (1984) Demonstration of an extracellular matrix in multicellular tumor spheroids. Cancer Res. 44, 3090-7.
    • (1984) Cancer Res , vol.44 , pp. 3090-3097
    • Nederman, T.1    Norling, B.2    Glimelius, B.3    Carlsson, J.4    Brunk, U.5
  • 37
    • 0025655510 scopus 로고
    • Cell sorting with Hoechst or carbocyanine dyes as perfusion probes in spheroids and tumors
    • Durand, R. E., Chaplin, D. J., and Olive, P. L. (1990) Cell sorting with Hoechst or carbocyanine dyes as perfusion probes in spheroids and tumors. Methods Cell Biol. 33, 509-18.
    • (1990) Methods Cell Biol , vol.33 , pp. 509-518
    • Durand, R.E.1    Chaplin, D.J.2    Olive, P.L.3
  • 38
    • 0036288924 scopus 로고    scopus 로고
    • Adeno-associated viral vectors penetrate human solid tumor tissue in vivo more effectively than adenoviral vectors
    • Enger, P. O., Thorsen, F., Lonning, P. E., Bjerkvig, R., and Hoover, F. (2002) Adeno-associated viral vectors penetrate human solid tumor tissue in vivo more effectively than adenoviral vectors. Hum. Gene Ther. 13, 1115-25.
    • (2002) Hum. Gene Ther , vol.13 , pp. 1115-1125
    • Enger, P.O.1    Thorsen, F.2    Lonning, P.E.3    Bjerkvig, R.4    Hoover, F.5
  • 40
    • 34547221119 scopus 로고    scopus 로고
    • Transfection study using multicellular tumor spheroids for screening non-viral polymeric gene vectors with low cytotoxicity and high transfection efficiencies
    • Han, M., Bae, Y., Nishiyama, N., Miyata, K., Oba, M., and Kataoka, K. (2007) Transfection study using multicellular tumor spheroids for screening non-viral polymeric gene vectors with low cytotoxicity and high transfection efficiencies. J. Controlled Release 121, 38-48.
    • (2007) J. Controlled Release , vol.121 , pp. 38-48
    • Han, M.1    Bae, Y.2    Nishiyama, N.3    Miyata, K.4    Oba, M.5    Kataoka, K.6
  • 41
    • 33646946725 scopus 로고    scopus 로고
    • pH-responsive three-layered PEGylated polyplex micelle based on a lactosylated ABC triblock copolymer as a targetable and endosome-disruptive nonviral gene vector
    • Oishi, M., Kataoka, K., and Nagasaki, Y. (2006) pH-responsive three-layered PEGylated polyplex micelle based on a lactosylated ABC triblock copolymer as a targetable and endosome-disruptive nonviral gene vector. Bioconjugate Chem. 17, 677-88.
    • (2006) Bioconjugate Chem , vol.17 , pp. 677-688
    • Oishi, M.1    Kataoka, K.2    Nagasaki, Y.3
  • 42
    • 42149163566 scopus 로고    scopus 로고
    • Enhanced growth inhibition of hepatic multicellular tumor spheroids by lactosylated poly(ethylene glycol)-siRNA conjugate formulated in PEGylated polyplexes
    • Oishi, M., Nagasaki, Y., Nishiyama, N., Itaka, K., Takagi, M., Shimamoto, A., Furuichi, Y., and Kataoka, K. (2007) Enhanced growth inhibition of hepatic multicellular tumor spheroids by lactosylated poly(ethylene glycol)-siRNA conjugate formulated in PEGylated polyplexes. ChemMedChem 2, 1290-97.
    • (2007) ChemMedChem 2 , pp. 1290-1297
    • Oishi, M.1    Nagasaki, Y.2    Nishiyama, N.3    Itaka, K.4    Takagi, M.5    Shimamoto, A.6    Furuichi, Y.7    Kataoka, K.8
  • 44
    • 0031455518 scopus 로고    scopus 로고
    • Modulation of chemosensitivity through altered expression of cell cycle regulatory genes in cancer
    • Hochhauser, D. (1997) Modulation of chemosensitivity through altered expression of cell cycle regulatory genes in cancer. Anti-Cancer Drugs 8, 903-910.
    • (1997) Anti-Cancer Drugs , vol.8 , pp. 903-910
    • Hochhauser, D.1
  • 45
    • 33750207622 scopus 로고    scopus 로고
    • Relaxin expression from tumor-targeting adenoviruses and its intratumoral spread, apoptosis induction, and efficacy
    • Kim, J. H., Lee, Y. S., Kim, H., Huang, J. H., Yoon, A. R., and Yun, C. O. (2006) Relaxin expression from tumor-targeting adenoviruses and its intratumoral spread, apoptosis induction, and efficacy. J. Natl. Cancer Inst. 98, 1482-93.
    • (2006) J. Natl. Cancer Inst , vol.98 , pp. 1482-1493
    • Kim, J.H.1    Lee, Y.S.2    Kim, H.3    Huang, J.H.4    Yoon, A.R.5    Yun, C.O.6
  • 46
    • 0030453783 scopus 로고    scopus 로고
    • Relaxin induces an extracellular matrix-degrading phenotype in human lung fibroblasts in vitro and inhibits lung fibrosis in a murine model in vivo
    • Unemori, E. N., Pickford, L. B., Salles, A. L., Piercy, C. E., Grove, B. H., Erikson, M. E., and Amento, E. P. (1996) Relaxin induces an extracellular matrix-degrading phenotype in human lung fibroblasts in vitro and inhibits lung fibrosis in a murine model in vivo. J. Clin. Invest. 98, 2739-45.
    • (1996) J. Clin. Invest , vol.98 , pp. 2739-2745
    • Unemori, E.N.1    Pickford, L.B.2    Salles, A.L.3    Piercy, C.E.4    Grove, B.H.5    Erikson, M.E.6    Amento, E.P.7
  • 48
    • 34547818203 scopus 로고    scopus 로고
    • Rat liver sinusoidal endothelial cells survive without exogenous VEGF in 3D perfused co-cultures with hepatocytes
    • Hwa, A., Fry, R., Sivaraman, A., So, P., Samson, L., Stolz, D., and Griffith, L. (2007) Rat liver sinusoidal endothelial cells survive without exogenous VEGF in 3D perfused co-cultures with hepatocytes. FASEB J. 21, 2564-2579.
    • (2007) FASEB J , vol.21 , pp. 2564-2579
    • Hwa, A.1    Fry, R.2    Sivaraman, A.3    So, P.4    Samson, L.5    Stolz, D.6    Griffith, L.7
  • 49
    • 0028067243 scopus 로고
    • Paracrine interactions between fibroblasts and endothelial-cells in a serum-free coculture model - modulation of angiogenesis and collagen gel contraction
    • Villaschi, S., and Nicosia, R. (1994) Paracrine interactions between fibroblasts and endothelial-cells in a serum-free coculture model - modulation of angiogenesis and collagen gel contraction. Lab. Invest. 71, 291-299.
    • (1994) Lab. Invest , vol.71 , pp. 291-299
    • Villaschi, S.1    Nicosia, R.2
  • 50
    • 34548421162 scopus 로고    scopus 로고
    • Evaluation of poly (glycerol-adipate) nanoparticle uptake in an in vitro 3-D brain tumor co-culture model
    • Meng, W., Kallinteri, P., Walker, D., Parker, T., and Garnett, M. (2007) Evaluation of poly (glycerol-adipate) nanoparticle uptake in an in vitro 3-D brain tumor co-culture model. Exp. Biol. Med. 232, 1100-1108.
    • (2007) Exp. Biol. Med , vol.232 , pp. 1100-1108
    • Meng, W.1    Kallinteri, P.2    Walker, D.3    Parker, T.4    Garnett, M.5
  • 51
    • 0037406639 scopus 로고    scopus 로고
    • Selective reovirus killing of bladder cancer in a co-culture spheroid model
    • Kilani, R., Tamimi, Y., Hanel, E., Wong, K., Karmali, S., Lee, P., and Moore, R. (2003) Selective reovirus killing of bladder cancer in a co-culture spheroid model. Virus Res. 93, 1-12.
    • (2003) Virus Res , vol.93 , pp. 1-12
    • Kilani, R.1    Tamimi, Y.2    Hanel, E.3    Wong, K.4    Karmali, S.5    Lee, P.6    Moore, R.7
  • 52
    • 0041343256 scopus 로고    scopus 로고
    • An in vitro airway wall model of remodeling
    • Choe, M., Sporn, P., and Swartz, M. (2003) An in vitro airway wall model of remodeling. Am. J. Physiol. 285, L427-L433.
    • (2003) Am. J. Physiol , vol.285
    • Choe, M.1    Sporn, P.2    Swartz, M.3
  • 53
    • 34250660588 scopus 로고    scopus 로고
    • Physiological 3D tissue model of the airway wall and mucosa
    • Choe, M., Tomei, A., and Swartz, M. (2006) Physiological 3D tissue model of the airway wall and mucosa. Nat. Protoc. 1, 357-362.
    • (2006) Nat. Protoc , vol.1 , pp. 357-362
    • Choe, M.1    Tomei, A.2    Swartz, M.3
  • 54
    • 40749093735 scopus 로고    scopus 로고
    • Effects of dynamic compression on lentiviral transduction in an in vitro airway wall model
    • Tomei, A., Choe, M., and Swartz, M. (2008) Effects of dynamic compression on lentiviral transduction in an in vitro airway wall model. Am. J. Physiol. 294, L79-L86.
    • (2008) Am. J. Physiol , vol.294
    • Tomei, A.1    Choe, M.2    Swartz, M.3
  • 55
    • 0038027286 scopus 로고    scopus 로고
    • The effects of cyclic stretch on gene transfer in alveolar epithelial cells
    • Taylor, W., Gokay, K. E., Capaccio, C., Davis, E., Glucksberg, M., and Dean, D. A. (2003) The effects of cyclic stretch on gene transfer in alveolar epithelial cells. Mol. Ther. 7, 542-9.
    • (2003) Mol. Ther , vol.7 , pp. 542-549
    • Taylor, W.1    Gokay, K.E.2    Capaccio, C.3    Davis, E.4    Glucksberg, M.5    Dean, D.A.6
  • 56
    • 33645664022 scopus 로고    scopus 로고
    • Lentiviral-mediated fetal gene therapy for monogenic disorders: Development of an in vitro rabbit model
    • Huang, L., Reebye, S., Yeung, A., Jia, W., and Skarsgard, E. (2006) Lentiviral-mediated fetal gene therapy for monogenic disorders: Development of an in vitro rabbit model. Fetal Diagn. Ther. 21, 241-245.
    • (2006) Fetal Diagn. Ther , vol.21 , pp. 241-245
    • Huang, L.1    Reebye, S.2    Yeung, A.3    Jia, W.4    Skarsgard, E.5
  • 58
    • 33745866920 scopus 로고    scopus 로고
    • In vitro culture of embryonic mouse intestinal epithelium: Cell differentiation and introduction of reporter genes
    • Quinlan, J., Yu, W., Hornsey, M., Tosh, D., and Slack, J. (2006) In vitro culture of embryonic mouse intestinal epithelium: cell differentiation and introduction of reporter genes. BMC Dev. Biol. 6, 24.
    • (2006) BMC Dev. Biol , vol.6 , pp. 24
    • Quinlan, J.1    Yu, W.2    Hornsey, M.3    Tosh, D.4    Slack, J.5
  • 62
    • 0036307066 scopus 로고    scopus 로고
    • Adeno-associated virus (AAV)-mediated gene transfer in respiratory epithelium and submucosal gland cells in human fetal tracheal organ culture
    • discussion 1051-7
    • Lim, F. Y., Martin, B. G., SenaEsteves, M., Radu, A., and Crombleholme, T. M. (2002) Adeno-associated virus (AAV)-mediated gene transfer in respiratory epithelium and submucosal gland cells in human fetal tracheal organ culture. J Pediatr. Surg. 37, 1051-7, discussion 1051-7.
    • (2002) J Pediatr. Surg , vol.37 , pp. 1051-1057
    • Lim, F.Y.1    Martin, B.G.2    SenaEsteves, M.3    Radu, A.4    Crombleholme, T.M.5
  • 63
    • 0028795644 scopus 로고
    • Adeno-associated virus vectors transduce primary cells much less efficiently than immortalized cells
    • Halben, C. L., Alexander, I. E., Wolgamot, G. M., and Miller, A. D. (1995) Adeno-associated virus vectors transduce primary cells much less efficiently than immortalized cells. J. Virol. 69, 1473-9.
    • (1995) J. Virol , vol.69 , pp. 1473-1479
    • Halben, C.L.1    Alexander, I.E.2    Wolgamot, G.M.3    Miller, A.D.4
  • 64
    • 0032992225 scopus 로고    scopus 로고
    • Transduction of well-differentiated airway epithelium by recombinant adeno-associated virus is limited by vector entry
    • Bals, R., Xiao, W., Sang, N., Weiner, D. J., Meegalla, R. L., and Wilson, J. M. (1999) Transduction of well-differentiated airway epithelium by recombinant adeno-associated virus is limited by vector entry. J. Virol. 73, 6085-8.
    • (1999) J. Virol , vol.73 , pp. 6085-6088
    • Bals, R.1    Xiao, W.2    Sang, N.3    Weiner, D.J.4    Meegalla, R.L.5    Wilson, J.M.6
  • 66
    • 33745228071 scopus 로고    scopus 로고
    • High-density culture of hepatocytes in a packed-bed bioreactor using a fibrous scaffold from plant
    • Chen, J. P., and Lin, T. C. (2006) High-density culture of hepatocytes in a packed-bed bioreactor using a fibrous scaffold from plant. Biochem. Eng. J. 30, 192-198.
    • (2006) Biochem. Eng. J , vol.30 , pp. 192-198
    • Chen, J.P.1    Lin, T.C.2
  • 67
    • 38349063305 scopus 로고    scopus 로고
    • Development of an osteoblast-based 3D continuous-perfusion microfluidic system for drug screening
    • Jang, K., Sato, K., Igawa, K., Chung, U., and Kitamori, T. (2008) Development of an osteoblast-based 3D continuous-perfusion microfluidic system for drug screening. Anal. Bioanal. Chem. 390, 825-832.
    • (2008) Anal. Bioanal. Chem , vol.390 , pp. 825-832
    • Jang, K.1    Sato, K.2    Igawa, K.3    Chung, U.4    Kitamori, T.5
  • 68
    • 33846032329 scopus 로고    scopus 로고
    • A microfluidic platform for 3-dimensional cell culture and cell-based assays
    • Kim, M., Yeon, J., and Park, J. (2007) A microfluidic platform for 3-dimensional cell culture and cell-based assays. Biomed. Microdevices 9, 25-34.
    • (2007) Biomed. Microdevices , vol.9 , pp. 25-34
    • Kim, M.1    Yeon, J.2    Park, J.3
  • 69
    • 34547905048 scopus 로고    scopus 로고
    • Microfluidic tissue model for live cell screening
    • Lee, P., Gaige, T., Ghorashian, N., and Hung, P. (2007) Microfluidic tissue model for live cell screening. Biotechnol. Prog. 23, 946-951.
    • (2007) Biotechnol. Prog , vol.23 , pp. 946-951
    • Lee, P.1    Gaige, T.2    Ghorashian, N.3    Hung, P.4
  • 71
    • 19744379722 scopus 로고    scopus 로고
    • Three-dimensional micro-culture system with a silicon-based cell array device for multi-channel drug sensitivity test
    • Torisawa, Y., Shiku, H., Yasukawa, T., Nishizawa, M., and Matsue, T. (2005) Three-dimensional micro-culture system with a silicon-based cell array device for multi-channel drug sensitivity test. Sens. Actuators, B 108, 654-659.
    • (2005) Sens. Actuators, B , vol.108 , pp. 654-659
    • Torisawa, Y.1    Shiku, H.2    Yasukawa, T.3    Nishizawa, M.4    Matsue, T.5
  • 72
    • 40349113355 scopus 로고    scopus 로고
    • A high throughput perfusion-based microbioreactor platform integrated with pneumatic micropumps for three-dimensional cell culture
    • Wu, M., Huang, S., Cui, Z., Cui, Z., and Lee, G. (2008) A high throughput perfusion-based microbioreactor platform integrated with pneumatic micropumps for three-dimensional cell culture. Biomed. Microdevices 10, 309-319.
    • (2008) Biomed. Microdevices , vol.10 , pp. 309-319
    • Wu, M.1    Huang, S.2    Cui, Z.3    Cui, Z.4    Lee, G.5
  • 73
    • 0037563810 scopus 로고    scopus 로고
    • Microfluidic patterning of cells in extracellular matrix biopolymers: Effects of channel size, cell type, and matrix composition on pattern integrity
    • Tan, W., and Desai, T. A. (2003) Microfluidic patterning of cells in extracellular matrix biopolymers: effects of channel size, cell type, and matrix composition on pattern integrity. Tissue Eng. 9, 255-67.
    • (2003) Tissue Eng , vol.9 , pp. 255-267
    • Tan, W.1    Desai, T.A.2
  • 74
  • 75
    • 41049093795 scopus 로고    scopus 로고
    • A perfusable 3D cell-matrix tissue culture chamber for in situ evaluation of nanoparticle vehicle penetration and transport
    • Ng, C. P., and Pun, S. H. (2008) A perfusable 3D cell-matrix tissue culture chamber for in situ evaluation of nanoparticle vehicle penetration and transport. Biotechnol. Bioeng. 99, 1490-1501.
    • (2008) Biotechnol. Bioeng , vol.99 , pp. 1490-1501
    • Ng, C.P.1    Pun, S.H.2
  • 76
    • 0033302303 scopus 로고    scopus 로고
    • Transport of molecules, particles, and cells in solid tumors
    • Jain, R. K. (1999) Transport of molecules, particles, and cells in solid tumors. Annu. Rev. Biomed. Eng. 1, 241-263.
    • (1999) Annu. Rev. Biomed. Eng , vol.1 , pp. 241-263
    • Jain, R.K.1
  • 78
    • 2942632966 scopus 로고    scopus 로고
    • PEGylation significantly affects cellular uptake and intracellular trafficking of non-viral gene delivery particles
    • Mishra, S., Webster, P., and Davis, M. E. (2004) PEGylation significantly affects cellular uptake and intracellular trafficking of non-viral gene delivery particles. Eur. J. Cell. Biol. 83, 97-111.
    • (2004) Eur. J. Cell. Biol , vol.83 , pp. 97-111
    • Mishra, S.1    Webster, P.2    Davis, M.E.3
  • 80
    • 34248136491 scopus 로고    scopus 로고
    • Programmed drug delivery: Nanosystems for tumor targeting
    • Wagner, E. (2007) Programmed drug delivery: nanosystems for tumor targeting. Expert Opin. Biol. Ther. 7, 587-593.
    • (2007) Expert Opin. Biol. Ther , vol.7 , pp. 587-593
    • Wagner, E.1
  • 81
    • 1242292972 scopus 로고    scopus 로고
    • Collagenolytic proteases from bacteria
    • Watanabe, K. (2004) Collagenolytic proteases from bacteria. Appl. Microbiol. Biotechnol. 63, 520-526.
    • (2004) Appl. Microbiol. Biotechnol , vol.63 , pp. 520-526
    • Watanabe, K.1
  • 82
    • 0042358985 scopus 로고    scopus 로고
    • Cell culture: Biology's new dimension
    • Abbott, A. (2003) Cell culture: Biology's new dimension. Nature 424, 870-872.
    • (2003) Nature , vol.424 , pp. 870-872
    • Abbott, A.1
  • 84
    • 34648837293 scopus 로고    scopus 로고
    • Culture of HepG2 liver cells on three dimensional polystyrene scaffolds enhances cell structure and function during toxicological challenge
    • Bokhari, M., Carnachan, R. J., Cameron, N. R., and Przyborski, S. A. (2007) Culture of HepG2 liver cells on three dimensional polystyrene scaffolds enhances cell structure and function during toxicological challenge. J. Anat. 211, 567-76.
    • (2007) J. Anat , vol.211 , pp. 567-576
    • Bokhari, M.1    Carnachan, R.J.2    Cameron, N.R.3    Przyborski, S.A.4


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